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Fan Animators
Game Mods
The Game Itself
- Auri Mod
- The Binding of Isaac: Antibirth (Would later be altered and merged with the base game when The Binding Of Isaac: Repentance was released.)
- The Binding Of Isaac: Epiphany
- The Binding of Isaac: Revelations
- The Binding Of Isaac Whybirth
- Fiend Folio
- Isaac Survivors (based on Vampire Survivors)
- Rebekah: The Cursed and Brokenhearted Expansion
- Reverie - Touhou Combinations (Crossover with Touhou Project)
- Samael
Other
- Vs Isaac (Crossover mod for Friday Night Funkin')
Fan Games