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Tiago Marques
Voiced by: Peter Marinker, Emma Tate (young)
- Dark Is Not Evil: He and the Gnostics treat Lucifer as a god like Jehovah.
- Follow in My Footsteps: He wants her daughter Eva to continue their family tradition. Unfortunately, this causes Eva to leave her father.
- Grumpy Old Man: Complains that his thighs are aching after he climbs up the stairs.
- Last-Name Basis: He is addressed by George and Nico through his last name.
- Mr. Exposition: He explains the history of Gnosticism as well as his ancestors, the Cathars.
- Plot-Triggering Death: His death is the reason why Eva decides to continue their tradition.
- The Prankster: When George shows Trevor to Marques, Marques tells him that when he was a child he had fun keeping ferrets in his pants.
- Senior Sleep-Cycle: He falls asleep easily whenever he's tired.
- Tragic Keepsake: He has the Ouroboros necklace, which belonged to his father.
Eva Marques
Voiced by: Shelley Longworth
- Action Girl: She's willing to kick henchmen's butt and shown that she's capable of handling a rifle.
- Agent Scully: She doesn't understand her father's dedication in Gnosticism. She changes her mind after remembering what Langham did to her father.
- I Just Want to Be Normal: She doesn't want to experience the same tragedy in her family again. At the end of the game, she accepts her responsibility as a Gnostic leader after she saw her father's death.
- Like Father, Like Son: She inherited her temperament from her father.
- Meaningful Name: Eva is the Spanish counterpart of "Eve", which derived from a Hebrew name meaning "life" or "living one". Also, she is named after the first woman that God created.
- Miss Kitty: She owns a bar in Marseilles.
- Missing Mom: Her mother died a long time ago.
- Precision F-Strike: She's about to say something offensive about her father's religion when George stops her.
- The Runaway: She left her father at the age of eighteen because she couldn't stand her father's interest in Gnosticism. She returns back home after she finds out that her father is in danger.
- Shipper on Deck: She thinks that George and Nico are a couple.
- Tomboy: Eva has some shades of this. She is less interested with men and hates flowers.
- You Killed My Father: Eva is angry and devastated after she sees Langham shoot her father.
Richard Langham
Voiced by: Nicholas Boulton
- Dead Guy Junior: He was named after his grandfather.
- Dead Person Impersonation: In Episode 2, he is revealed as the grandson of Gehnen and shares his name. Richard Langham is a stolen identity, the real Langham "went for a swim in the Seine". Despite this, George continues to call him Langham because he finds it easier.
- Dirty Cop: At the end of part one, he leaves George and Nico stranded in a burning building.
- Foreshadowing: At the gallery, he is surprised when George mentions the devil.
- Identical Grandson: He looks like his grandfather Gehnen.
- Interpol Special Agent: Major in art theft.
- Last-Name Basis: He is addressed by George and Nico through his last name.
- Not-So-Well-Intentioned Extremist: He claims that raising Lucifer and killing Jehovah will set humanity free. But more sinister motifs become apparent towards the end.
- Parody Name: Of Robert Langdon.
- Reasonable Authority Figure: Subverted. When Langham enters the picture, he believes George and Nico's story, unlike Navet. However, it turns out Langham is not who he pretends to be.
- Smug Snake: He acts nice to everyone, but he couldn't care less besides getting the power of Lucifer for himself.
- Stripped to the Bone: Like Karzac before him, he also becomes a skeleton upon death before his bones disintegrate.
- Walking Spoiler: This article is covered with spoilers: There's a lot more to this detective gentleman than meets the eye.
Roman Medovsky
Voiced by: Kerry Shale
- Good Smoking, Evil Smoking: He has a cigarette box on his study room.
- Husky Russkie: Medovsky has a Russian-like accent.
- Last-Name Basis: His first name is rarely mentioned in the game.
- No Celebrities Were Harmed: Many fans notice that he looks a lot like Vladimir Putin.
- Red Herring: In Episode 2, Medovsky is shown to have no interest in the painting other than its value. In fact, he only attempts to kill George because one of his rare Russian coins entered George's deep pockets and never returned!
- Russian Guy Suffers Most: Subverted. He does die, but his death isn't gruesome compared to Langham.
- Villain with Good Publicity: He has a picture of him shaking hands with Muammar Gaddafi.
Shears
Voiced by: Rob Rackshaw
- Accidental Murder: It is revealed in Episode 2 that he shot Henri, however he claims that this was not his intention and he only wanted to hurt him a little.
- Call to Agriculture: He likes to tend the topiary.
- Camp Cook: He's preparing kebabs while George and Nico are inside the Eden. Unfortunately, he uses Donna as a main ingredient.
- Cultured Badass: He's Medovsky's assistant who loves art and philosophy.
- Desperately Looking for a Purpose in Life: He asks Nico about free will in Monserrat cable car station.
- Easily Forgiven: By George and Nico.
- Friend to All Living Things: He likes goats as much as Nico does.
- Karma Houdini: Accidental Murder or not, he's still responsible of the death of Henri, yet doesn't seem to receive any kind of punishment in the end.
- Line-of-Sight Name: In Episode 1, George wonders if Shears' mother christened her son after a tool for cutting plants.
- Moment Killer: To George and Nico at the end of the game.
- MookâFace Turn: During a standoff late in Episode 2, Nico convinces him to be his own man, so he shoots his former boss to save George. He then accompanies the heroes to the end of the game.
- Tattoo as Character Type: He has a tattoo on the back of his arm. It reads "Head Hunters".
Father Simeon
Voiced by: Terry Wilton
- Dark Is Evil: He believes that Lucifer represents the evil force.
- Dead Person Conversation: He appears in George's dream. He tells George not to believe in Tiago or Hobbs.
- Killed Mid-Sentence: He is killed in Le Lizard Bleu before he tells George who the murderer is.
- Large Ham: He always says that the painting is cursed by the devil.
- Mr. Exposition: He provides some information regarding the Gnostics and Tabula Veritatis.
- Turbulent Priest: He and other Dominican priests are seeking the remaining Gnostics to destroy them.
Henri Dubois
Voiced by: Neil Richards
- Idol Singer: He was a singer to his own band "The Hairy Lobsters"
- New-Age Retro Hippie: He has a lot of hippie related stuff in his office.
- Nice Guy: He seems to be a good person who genuinely loves Bijou to the point where he buys expensive things for her.
- Posthumous Character: He is killed while trying to protect the painting.
Bijou Dubois
Voiced by: Roz Landor
- Gold Digger: She spends a lot of money, but she still loves Henri.
- Jerkass: She and Mr. Hobbs faked the provenance and forged the La Maledicció. They hid the real painting in Hobb's studio.
- Love Triangle: She was in one with Henri and Hobbs. Unlike Imelda, Bijou loves her men.
- Meaningful Name: Her name means "jewel", and she often receives gifts from her husband.
- Reclining Reigner: She does this pose while her husband's grave is inside their apartment.
Wilfred "Wilfy" Hobbs
Voiced by: Toby Longworth
- The Alcoholic: He prefers whiskey and carries a bottle of it on his van.
- All Men Are Perverts: He receives a letter complaint from some agencies for having sexual relationships with the models.
- Dead Person Conversation: He appears in George's dream. He tells George that he must side with Lucifer and enjoy the pleasures instead of saving mankind.
- Asshole Victim: He is killed by Langham in his studio.
- Affectionate Nickname: Bijou calls him "Wilf".
- Can't Hold His Liquor: He has weakness for whiskey and loses his concentration in painting pictures.
- Jerkass: He and Bijou forged the provenance and the La Maledicció. They hid the real painting in Hobbs' studio.
- Secret Relationship: He has a love affair with Bijou.
Gehnen
Voiced by: Charles Cecil (Episode One), Rolf Saxon (Episode Two)
- Adventurer Archaeologist: In the game's comic, he wears one when he travelled in Turkey.
- Ambition Is Evil: His efforts to find Jehova and Lucifer's powers result in his death.
- Ate His Gun: Gehnen was trapped in the secret chapel cave. However, unlike Klausner in Syria, Gehnen simply blew his own brains out.
- Bad Boss: According to Ramon, the henchmen who invaded Xavier's house hated Gehnen and they were forced to search him in Catalonia for weeks.
- Corrupt Corporate Executive: He is the owner of a mining company.
- Dead Man Writing: In his last letter, he says that he managed to translate the Tabula Veritatis. The letter also contains five locations he pinpointed based on the Tabula.
- Doomed Predecessor: He is first mentioned in the Distant Prologue, set in 1937, where he gains access to information about the Tabula Veritatis. We learn that he spent weeks making notes and studying maps before disappearing without a trace. Some 85 years later, George and Nico find his corpse in a secret cavity at Santa Cova. He got trapped there because of a missing object, a medallion now in George's possession which leads the way out of the cave. Gehnen Ate His Gun before dying of dehydration. Next to his corpse George finds the Tabula Veritatis and also a map with clues to the location of the "Paradise" that Gehnen scripted down before his death.
- Villain Opening Scene: The opening starts out when he drives his car to Xavier's house. He enters the library and steals the La Melledicció.
Inspector Auguste Navet
Voiced by: Tim Bentinck
- Bad Boss: Not a very pleasant person with his subordinate.
- Clueless Detective: He displays no talent whatsoever at solving the crime despite the praise we hear from Sergeant Moue. How this guy managed to become a detective is the true mystery of the game. Navet can't even tell the difference between blood and tomato sauce!
- Declarative Finger: Usually when he starts the investigation.
- Glad I Thought of It: Navet's reaction after George got his crime reconstruction machine to work.
- Jerkass: A grandiloquent idiot who immediately antagonizes George and is not very nice with his underling, Sergeant Moue.
- The Lab Rat: He's more interested in examining biological samples than investigating other cases.
- Never My Fault: He blames Moue for breaking the crime reconstruction machine.
- Small Name, Big Ego: For all his talks of being an "expert" when it comes to biological samples, he can't see the difference between blood and tomato sauce.
- What Happened to the Mouse?: He isn't mentioned in the second episode.
Ramon
Voiced by: David Shaw-Parker, Joe Richards (young)
- Drowning My Sorrows: He closed the library and drank a lot of brandy on the memory of Xavier and Hernandez's death. As a result, Ramon lost the library key and never remembered where it is.
- Friendless Background: He even lampshades it.
- Intergenerational Friendship: With Xavier and Hernandez.
- Named After Somebody Famous: Ramon is named after Xavier's favorite saint, St Ramon, the patron of falsely accused. The name also means "protector".
- Tap on the Head: According to the game's storyboard, he was knocked out by one of Gehnen's henchmen.
- Undying Loyalty: He served Tiago's family since he was a boy.
Bassam
Voiced by: Wayne Forester
- Abandoned Area: His stall is located in a dead mall, where every store but the one for Vera Security is long gone. As a result, he's really happy to get business from George.
- Flat Character: He doesn't really have any personality beyond being a shopkeeper, but is quite happy to help George with his investigation.
- Leitmotif: "Bassam's Kingdom".
- Meaningful Name: To his store, "Aladdin" (named at George's suggestion). The phrase 'Aladdin's Cave' is often used to describe a store that sells a variety of unusual things.
- Non-Specifically Foreign: He's originally from an Arabic country and speaks perfect English, and likes selling stuff from all over the world. It's not stated why he decided to study in France, but it's possible he may be from a North African country (and therefore know French well too), which would be Truth in Television.
- Starving Student: He tries his best to enter college by selling strange trinkets from different countries.
Annette Maxim
Voiced by: Nicolette McKenzie
- The Gambling Addict: She often bets on race horsing.
- Why Did It Have to Be Snakes?: She hates cockroaches like Trevor.
Adam
- Collector of the Strange: He likes to collect coins and stuff with pugs.
- Friend to All Living Things: He likes pugs.
Kat D
- Curtain Camouflage: Kat hides in the closet to avoid Langham and his henchmen.
El Serp
- All There in the Manual: It is revealed from the game's character sheets that his real name is Hernandez.
- Meaningful Name: It means "The Serpent" in Spanish. He was named after the Ouroboros symbol.
Xavier Marques
- Death by Origin Story: His death is the reason why Tiago becomes a Gnostic leader.
- Intergenerational Friendship: With Ramon.
- The Leader: He was a leader of the Gnostics.
- Posthumous Character: He was killed by the fascists after taking the painting.
Hernandez
Voiced by: Juan Manuel Delfin
- Hidden Depths: He was El Serp, the painter who created La Maledicció.
- Intergenerational Friendship: With Ramon.