History Main / IntoxicationEnsues

* Team Rocket get stoned in the infamous "Shuckle Juice" ''{{Anime/Pokemon}}'' episode after being told it attracts Pokemon. It also makes them want to kiss each other.

* [[TropeNamer The]] MushroomSamba from ''Anime/CowboyBebop''. The crew (minus Ed) eat some mushrooms that cause them to start hallucinating, with Spike imagining walking up an endless flight of stairs and talking to a frog, Jet talking to his bonsai trees and "discovering the secret of the universe", and Faye swimming through air while imagining she's swimming in the ocean.

* ''Manga/InuYasha'':

** The ride in question is at the beer-themed "Duffland," so there's at least a possibility it's not actually water.

** In "D'oh-in in the Wind", he destroys the hippies' vegetable juice business by accidentally jamming the bottling machine with a novelty flying disc. He makes up for it by picking all the other vegetables and putting them in the juicer, which turn out to be the hippies' "private vegetables"; we see a montage of townsfolk hallucinations and such, and Chief Wiggum tastes it and comments that "it's nothing but carrot juice and peyote."

* The fandom isn't sure ''just'' what happened in the ''LightNovel/HaruhiSuzumiya'' short story ''Remote Island Syndrome''; all we know is that [[UnreliableNarrator Kyon]] mentions secondhand stories from Itsuki that he and Haruhi got drunk and acted "[[NoodleIncident quite disgracefully]]", which isn't shown in the anime. Naturally, {{WMG}}s abound.

* The entire plot of ''Series/{{Star Trek|The Original Series}}'' episode "The Naked Time". The entire crew is exposed to an intoxicating substance and those with any sense left must figure out how to run the ship and save the crew while their crewmates go crazy and their own brains threaten to turn on them.

** In "Three of a Kind", Agent Scully is injected with a brainwashing drug to make her forget some evidence she's uncovered, one of its side-effects being the inhibition of higher reasoning. We later see her enthusiastically flirting with an all-male group of defense contractors and TheMenInBlack; fortunately Melvin Frohike hauls her away, much to their disappointment.
** The episode "Bad Blood" featured a drugged Mulder singing the theme from "Shaft".
*** [[SuspiciouslySpecificDenial HE DID NOT]].
** In "Anasazi", the conspirators have been drugging water in Mulder's building to make him irrational and violent. There was a murder due to the drugs.
** "Never Again": Ed Jerse's tattoo of a seductive girl named Betty talks to him and forces him to do horrible things. It's revealed that the red tattoo ink was made from rye and contained ergot alkaloid which caused his auditory and visual hallucinations. Scully got a tattoo as well, but was not affected to that extent.

* [[WesternAnimation/TheAmazingWorldOfGumball The Amazing World of Gumball]]: The episode “The Flakers” is about the kids being forced to watch Richard while he is on anesthetics after a dentist’s appointment. He spends the entire episode in his underwear and mistakes literally everything for food, such as a telephone as an ice cream cone and Rocky as a burger.

* In ''WesternAnimation/CentralPark'', Season 1 "[[Recap/CentralParkS1E4GarbageBallet Garbage Ballet]]", Paige is sick and may have took too much cough syrup as she starts acting delirious, like imagining Cole's sock as a rat and starts getting paranoid about rats.

* An episode of ''WesternAnimation/DextersLaboratory'' has him and Dee-Dee try coffee to see what all the fuss is about. They end up consuming all the coffee in the house and going on a hyperactive bender. Meanwhile their parents learn that they are out of coffee and go through the effects of withdrawal. Interesting fact: while Dee-Dee spent her excessive energy playing plenty of different games and activities, Dexter keeps tightening the same bolt for possibly ''hours'', all while smiling like a stoner.

** Brian ingests a large handful (er, [[TalkingAnimal pawful]]) of magic mushrooms ([[OrSoIveHeard one or two is usually more than sufficient)]] and having a really bad trip that Stewie helps him through.

* ''Series/TheAfterparty'': Aniq takes a swig from Chelsea's flask, thinking it's a regular drink. He gets woozy very fast when he arrives at the party and starts spouting nonsense and mistaking candles for jello shots before passing out. Chelsea's testimony reveals he had actually drank [[spoiler:cat tranquilizers]].
* ''Series/ComedyCentralRoastOfPamelaAnderson'': Several of the roasters got noticeably drunk and drunker over the course of the show. This goes double for Courtney Love, who started off trashed and got worse from there.

** In a darker inversion, in "[[Recap/AngelS01E17Eternity Eternity]]", a lonely movie star on season one of gives Angel a happiness inducing drug without him realizing it. What she doesn't know is that she doesn't want Angel to get happy, as he (this time temporarily) turns evil and tries to kill her.

* Ever watch a cat come off of tranquilizers? HilarityEnsues

* ''WebOriginal/MultituberculateEarth'': Liberal use of a picture of a ''Nunduapis tricolor'' getting drunk on fermented fruit occurs in several pages, such as the start of the entry to the [[https://multituberculateearth.wordpress.com/2022/03/27/eocene/ Eocene]]. Notably, the picture was commissioned before the project, but since reappropriated.

* The ''WesternAnimation/{{Amphibia}}'' episode "Adventures in Catsitting" ends with Anne returning home high on dental painkillers and extremely delirious and incoherent as a result, blurting out an [[WordSaladPhilosophy incredibly nonsensical]] IceCreamKoan about Domino while squeezing Hop Pop's cheeks.

* In 2014, BBC Middle East correspondent Quentin Sommerville and his crew were reporting on the burning of over eight and a half tons of heroin, opium, hash and other assorted narcotics in [[UsefulNotes/TheWarOnTerror Afghanistan]], but stood a little too close to the flames. The result? [[https://www.youtube.com/watch?v=kLYVTdiACRA One very giggly correspondent.]]

%%* [[http://notalwaysrelated.com/graduated-to-schedule-one/37113 Pot brownies]] at a graduation party, and a 12-year-old cousin who thought they were normal brownies, courtesy of ''[[Website/NotAlwaysRelated Not Always Related]]''.

%%* [[http://notalwaysrelated.com/graduated-to-schedule-one/37113 Pot brownies]] at a graduation party, and a 12-year-old cousin who thought they were normal brownies, courtesy of ''[[NotAlwaysRight/SisterSites Not Always Related]]''.

* ''Series/CriminalMinds'' has perhaps the ''[[{{Deconstruction}} darkest]]'' take on this trope anywhere, when [[TheWoobie Reid]] is kidnapped by a man with three personalities: His abusive father, the angel Raphael, and the man himself, Tobias, who is meek and afraid of the others. After the first two torture Reid, Tobias gives him his own personal drug blend to help with the pain...and [[UnwittingInstigatorOfDoom ends up causing more trouble than the other two combined]], [[SurprisinglyRealisticOutcome since Reid becomes addicted. He has to struggle to get clean and it is mentioned in later seasons that he still goes to support meetings.]]

* Morwenna from ''Series/DocMartin'' became inexplicably, hilariously, hyper after trying some of her Grandad's old [=WW2=] energy pills. Turned out they were methamphetamine[[note]]yes, during [=WW2=] both sides issued methamphetamine pills to their soldiers to keep them awake[[/note]]. MoodWhiplash ensues when those same pills cause her Grandad to have a heart-attack.

* In the ''Series/MorkAndMindy'' episode, "Mork and the Family Reunion", Mindy accidentally eats [[AlienLunch an Orkan delicacy called flek]], and begins performing spontaneous gymnastics and acting, well, Mork-like. Later, Mindy's uncle (played by none other than Creator/RobinWilliams' RapidFireComedy idol, Jonathan Winters) eats some and HilarityEnsues big time.

** Aang is trying to unleash the Avatar State so the Earth Kingdom can attack the Fire Nation. He is given a tea that's supposed to stimulate his energy. He ends up going into CaffeineBulletTime instead.

* ''Series/IClaudius'' has a rare serious version where after Claudius finds out that his wife Messalina has been cuckolding him (something everyone else in Rome has known for years) and that she is on the verge of having him overthrown, his [[EvilChancellor evil]] [[PoisonousFriend but loyal chancellor]] gives him some drug which is supposed to calm his nerves. While on the substance, Claudius experiences delusions of grandeur and is able to calmly sign the death warrants of Messalina and the other 500 people at a party she held when plotting treason, something he would have been too kindly to do with a clear head.

* Creator/StephenColbert marked the demise of (father of LSD) Albert Hoffman when his interns made him a sheet of [[IntoxicationEnsues little stamps]]. [[http://www.colbertnation.com/the-colbert-report-videos/167613/may-08-2008/r-i-p--albert-hoffman He decides to pre-lick the entire sheet right away]]. The results start at ContemplatingYourHands and go all the way to an epic [[BreakingTheFourthWall fourth-wall-breaking]] freakout over whether he's a real person and why he does the things he does. He ends the show in his set's "fireplace" (a set piece looking like a brick fireplace with a flat-screen TV showing a burning fireplace fire) and claims that the fire looks fake. He had a similar reaction when he briefly ran out of the prescription painkillers he'd become addicted to.

** In a side chapter, Nemugasa gets drunk off of liquor infused chocolates, during which Maya takes the opportunity to engage in some sexual activity with Nemugasa that he knows sober [[InVinoVeritas Nemugasa would absolutely protest doing]].

* ''[[Machinima/FreemansMindSpinoffs Shepard's Mind]]'', a spinoff of ''Machinima/FreemansMind'', has this happen to the titular character in [[https://www.youtube.com/watch?v=1x_mcTSZXXA episode 19]], after consuming oxycodone [[BrickJoke found in Gordon Freeman's locker]] from the previous episode.

* Mike Birbiglia has a few routines about the effects painkillers and alcohol have on him. One has about how he had a drink while in a laundromat and believed himself to be in "a submarine in a sea of dirty clothes, with an all-Spanish crew. This resulted in him shouting for a course to be set for "permanent press" and for someone to bring him more quarters and a drink because "this place is starting to look like a laundromat!" Another involves him being whacked out on painkillers while with his mother in the waiting room of a doctor's office. As he put it, "this was not the first time I was high while in the same room as my mother, but it was the first time she knew about it."

* The notorious "Guacamole Incident" from the early years of ''WebOriginal/{{Fenspace}}'', which resembles (and was very likely directly inspired by) the actions of the "Merry Pranksters" as mentioned in the RealLife section... Except that unlike LSD, the effects of ingesting Handwavium are [[BalefulPolymorph a lot more drastic, and permanent]]. The incident contributed to massive public hysteria about the substance and soured relations between the United States and the nascent Fenspace Convention members for nearly a decade.

* In ''Film/TheHitmansWifesBodyguard'', Sonya gives Bryce some pills to help his broken ribs. The pills turn out to be lithium, causing Bryce to fall asleep during in the back of a van during a lengthy car chase.

* In ''Film/HitmansWifesBodyguard'', Sonya gives Bryce some pills to help his broken ribs. The pills turn out to be lithium, causing Bryce to fall asleep during in the back of a van during a lengthy car chase.