Asav is Superhuman
The Uncharted series does have supernatural elements. Asav said that the blood of the old kings ran through his veins. He might not be joking, and even worse the "Old Kings" might have been Deities or Demi-Gods, who passed down super human physiology to him. Maybe not at the level of Lazarevic in Among Thieves after he drank the sap from Tree Of Life, but his jumps and attacks have a supernatural weight behind them. Which might explain why Nadine was able to beat Nathan and Sam’s ass (Who themselves routinely take down crowds of goons in hand to hand combat) but got bested by a military geek. In other words Asav > Nadine > Nathan Drake.
