- Approval of God: The real Stephen Hawking liked the film so much that he allowed them to use his synthesised voice during the latter part of the film (as Hawking had his voice copyrighted, they had initially tried to remake it from scratch, but were not happy with the result).
- Dueling Movies: With The Imitation Game, starring Benedict Cumberbatch as Alan Turing. Amusingly, Cumberbatch himself played Stephen Hawking in the BBC film Hawking early in his career.
- Dyeing for Your Art: Besides studying Stephen Hawking, Eddie Redmayne spent time with other ALS patients to prepare him for the role. He also lost weight by skipping meals.
- Fake American: British actor Enzo Cilenti plays American physicist Kip Thorne.
- Star-Making Role: Eddie Redmayne, Felicity Jones, and Charlie Cox's careers all took off after the release of this movie.
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