Trivia / Lorenzo's Oil

• And Introducing: Zach O'Malley-Greenberg made his acting debut as Lorenzo Odone. It was his only film role, and he later went into journalism.
• Fake Nationality: American Nick Nolte as Italian Augusto Odone.
• Two Voices, One Character: While Zach O'Malley-Greenberg speaks in a majority of the film, some of the parts where Lorenzo was crying were voiced over by E.G. Daily.