Pre-series
- Cretaceous Period: Gorisaki Banana is sent back to this period somewhere in Northern Laurasia as a result of an unstable time vortex generated by the combined power of the five Phantom Ranger Keys, along with the Pink Phantom Ranger Key. He is recovered by Usada Lettuce, who followed him in Buster Machine RH-03 using the system data of GoZyuDrill. The Phantom Ranger Key ends up being taken by Zangyack. (Go-Busters vs. Gokaiger)
- 1972: Masato Jin/Beet Buster is born.
- 1984: Ryuji Iwasaki/Blue Buster is born.
- 1991: Hiromu Sakurada/Red Buster is born.
- 1995: Yoko Usami/Yellow Buster is born.
- 1999:
- Ryuji Iwasaki enters a robotics competition, but his mentor Masato Jin only gives him 2nd place for his work due to it being too perfect. (Mission 15)
- December 24: A computer virus infects the systems of the Transport Research Center, evolving rapidly into a powerful sentient form feeding on Enetron, an experimental energy source, and given the nickname of Messiah. In order to stop it's further spread, the center and many of it's workers, including the parents of Hiromu Sakurada, the mother of Yoko Usami and the senior of Ryuji Iwasaki were transported into Hyper Space so it would not conquer all systems on Earth. In order to protect them from the transport, the three children at the center are given a special anti-transport injection that grants them special abilities and computer-like nature which would allow them to fight back against Messiah when it began to attack Earth again. In another part of the abducted complex, researcher Masato Jin is likewise abducted but is able to evade Messiah; but is forced to work in secret on a means to be able to assist the survivors of the disaster outside of Hyperspace. (Mission 2)
- December 25, 2000: One year after the Messiah incident, Commander Kuroki and Ryuji Iwasaki begin to hold Christmas parties for young orphans at the Dainan Children's Center so they did not gain a hard heart for the day despite what happened a year prior. Yoko Usami likewise attends due to being in training with them from a young age. (Mission 43)
Series
- February 26, 2012: Now a widely-used power source in urban areas, Enetron is being targeted by a mysterious figure named Enter who leads the Vaglass, the term conned by the Energy Management Center for Messiah's followers. Having trained for this day, two agents who were the two of the three only known survivors of the events of Messiah's creation thirteen years ago are joined by the other survivor Hiromu Sakurada to fight the Vaglass as the Tokumei Sentai Go-Busters. The Go-Busters defeat Shovelloid/zord. (Mission 1)
- The Go-Busters defeat Burnerloid/zord. (Mission 2)
- The Go-Busters defeat Needleloid/zord. (Mission 3)
- The Go-Busters defeat Cutterloid/zord. (Mission 4)
- The Go-Busters defeat Tireloid/zord. (Mission 5)
- The Go-Busters defeat Sprayloid/zord. (Mission 6)
- The Go-Busters defeat Denshaloid/zord. (Mission 7)
- Masato Jin's blueprints for BC-04 are stolen when an inside man promises to provide Enter with it. Though the inside man goes back on his promise, Enter still manages to acquire them. However, making himself known to Kuroki, Masato sends his Buddyloid Beet J Stag from subspace to project an Avatar for the human to act through. The Go-Busters defeat Drilloid/zord. (Mission 8)
- The Go-Busters are embroiled in the battle between Tsukasa Kadoya (Kamen Rider Decade), Great Leader of Dai-Shocker, and Dai-Zangyack led by Emperor (formerly Captain) Marvelous (Gokai Red) who are hunting the Kamen Riders. (Super Hero Taisen)
- The Go-Busters rescue Yoko's Buddyroid, Usada Lettuce, from thugs. (Mission 9)
- The Go-Busters defeat Danganloid/zord. (Mission 10)
- The Go-Busters defeat Fanloid/zord. (Mission 11)
- The Go-Busters defeat Copyloid/zord. (Mission 12)
- The Go-Busters defeat Tubaloid/zord. (Mission 13)
- The Go-Busters defeat Tubaloid/zord 2. (Mission 14)
- Initially working on their own for Enetron resources, Masato eventually works with the Energy Management Center while providing the completed BC-04 and the SJ-05 to the EMC arsenal. The Go-Busters defeat Soujikiloid/zord. (Mission 15)
- Masato reveals his real body is still in subspace at another part of the transported facility. The Go-Busters defeat Parabolaloid/zord. (Mission 16)
- The Go-Busters defeat Forkloid/zord. (Mission 17)
- The Go-Busters defeat Drilloid/zord 2. (Mission 18)
- The Go-Busters defeat Spannerloid/zord. (Mission 19)
- The Go-Busters test drive the first generation Buster Machine FS-0O. Enter plots to use Tokyo Enetower to transport a dozen of its surrounding Enetron tanks to Hyper Space. The Go-Busters thwart his plan with the help of the combination Go-Buster Kero-Oh. (The Movie)
- Though his plan with the Filmzord failed with the formation of Great Go-Buster, Enter had the Subspace projection system installed in future megazord models. (Mission 20)
- The Go-Busters defeat Dumbbelloid/zord. (Mission 21)
- Enter's intent to delight Messiah's lust for human suffering results in the creation of Escape. The Go-Busters defeat Keyloid/zord. (Mission 22)
- The Go-Busters test the "protectors", a prototype for a future advancement in Go-Buster technology. Yoko and Jin forced to use it against Escape. The Go-Busters defeat Jisyakuloid/zord. (Mission 23)
- August 5, 2012: The Go-Busters defeat Wataameloid/zord. (Mission 24)
- The Go-Busters defeat Rousokuloid/zord. (Mission 25)
- The Go-Busters defeat Keshigomuloid/zord. (Mission 26)
- Using the work of a scientist who created a self-evolving program, Enter manages to use it on Messiah with the transformation slightly delayed. The Go-Busters defeat Mushikagoloid/zord. (Mission 27)
- September 2, 2012: Rika Sakurada wins an award for her work as a children's book illustrator. While looking through her works, Hiromu realizes that Escape's guns Gog & Magog are based on two dog statues formerly at the Sakurada home. The Go-Busters defeat Sprayloid/zord 2. (Mission 28)
- Despite Enter and Escape's attempt to stop them, the Go-Busters enter subspace where they face Messiah Cell, a physical construct of Messiah. (Mission 28)
- Eventually, Masato hiding the truth from them for the sake of mission, the primary Go-Busters learn that Enter and Escape are actually created from the digitized people (Hiromu and Yoko's parents included) that Messiah assimilated. Left to no choice but to honor the scientists' wishes to destroy Messiah so their family and friends can rest in peace, Hiromu uses Go-Buster Ace to destroy Messiah's core while fighting Enter in his Megazord Epsilon. (Mission 30)
- The Go-Busters encounter Shelly and Gavan Type G who are tracking an enemy from Makuu Space. Together they defeat Rhino Doubler. However, Enter is revealed to have survived the destruction of Messiah. (Mission 31, 32)
- The Go-Busters defeat Sunadokeiloid/zord. Enter later reveals that he was fighting Red Buster long enough to create back up data from Messiah: The Messiah Cards that he intends to use to have Messiah evolve by gathering data through the virus's Messiah Metaloid incarnations. As a countermeasure to the new Metaloid type. the primary Go-Busters use the finished "protectors" by merging with their Buddyroid to "Powered Custom" mode. (Mission 33)
- The Go-Busters defeat Puppetloid/zord. (Mission 34)
- The Go-Busters are joined by Tategami Li-Oh, a BuddyZord built by Dr. Hazuki to be compatible with Go-Buster Ace. (Mission 35)
- The Go-Busters defeat Bulldozerloid/zord. (Mission 36)
- November 4, 2012: Fearing Enter's plans for Messiah's data, Escape reach new heights by upgrading herself into "Escape Evolve" to undermine Enter. The Go-Busters defeat Tiaraloid/zord. (Mission 37)
- November 11, 2012: The Go-Busters defeat Domeloid/zord. (Mission 38)
- The Go-Busters defeat Karateloid/zord. (Mission 39)
- After taking a Messiah card while J. needed to restore Masato's real body, Enter wins Escape's loyalty by revealing that he assimilated another card prior that evolved him into "Enter Unite". The Go-Busters defeat Paraboloid/zord. (Mission 40)
- The Go-Busters defeat Loupeloid. (Mission 41)
- The Go-Busters team up with the Gokaigers to defeat Bacchus Gill. (Go-Busters Vs. Gokaiger)
- Enter arranged for a scheme to create Escape's personal Megazord Zeta, a vessel for Messiah's data. The Go-Busters defeat Denshaloid 2. (Mission 42)
- Once Escape learns of Enter's true intent to create a new Messiah rather than restore their creator to former glory, she seemingly destroys him and evolves Megazord Zeta into Messiah Reboot. (Mission 43)
- Having no more need of her, Messiah absorbs Escape's data and nearly defeats the Go-Busters before being finally destroyed. However, having assimilated the card he took from J. prior, Enter manages to reconstitute his data. (Mission 44)
- While celebrating New Year's Eve, the Go-Busters meet their match against Great Demon Lord Azazel and are killed in battle. However, meeting God, Nick attempted to avert this event by unknowingly creating an alternate continuity where Messiah never existed with the Doubutsu Sentai Go-Busters fighting the Machine Empire Mechalius. But when the results of Azazel killing the Go-Busters ends the same, Nick is inspired to have both Go-Buster teams join forces to defeat Azazel. But as the second wish negated the first, the second Go-Busters ceased to be. (Tokumei Sentai Go-Busters Returns vs. Doubutsu Sentai Go-Busters)
- Holiday Episode. (Mission 45)
- With only one Messiah Card to find, the Go-Busters find themselves in a new predicament when Enter resurfaces and obtained the power to create Metaloids from living organisms as he revealed by creating a flower-based version of Escape whose memory is reset between her destruction and recreation. Proclaiming himself as the new Messiah and confident to eventually higher life forms, Enter reveals that his back up is within the final Messiah Card that is located inside Hiromu's body. Enter further explains that the card has been gathering the data from its card siblings and thus gave Enter a better understanding on human nature. (Mission 46, 47, 48)
- As the other Go-Busters finally destroy an unstable animal-assimilating Escape, Red Buster's attempt to force Enter to remove the Messiah Card only resorted in Enter gaining the ability to become Dark Buster. Now able to convert all forms of matter, Enter proceeds to turn an Enetron plant and most of the people in it into a MegaZord Omega and repeat the process through out the city. However, being told of Masato's plan to remove the Messiah Card in the unstable Hyperspace, the Go-Busters manage to take Enter with them. (Mission 49)
- Though Enter attempts to grab Hiromu to bring him back to their reality, the others hold him off long enough for Masato to transfer the Messiah Card into his body, destroying them both as a result. With Enter unable to counter the turn of events, he dies fighting the Go-Busters before Masato's Avatar completely derezzes and the entire subspace dissolves. Luckily, the Go-Busters manage to return to their reality in time. With their mission finally over, the Go-Busters resume civilian life. (Final Mission)
Post-series
- 2013: The Go-Busters participate in the battle against Space Crime Syndicate Madou's army of revived monsters. (Super Hero Taisen Z)
- 2014: The Go-Busters team up with the Kyoryugers (As well as the Zyurangers and the Abarangers) to defeat Space War God Voldos. (Kyoryuger Vs. Go-Buster)
- 2017: The Go-Busters, among the first 38 Super Sentai, provide their power for the Ninningers and Zyuohgers to defeat Gillmarda. (Zyuohger vs. Ninninger)
- 2019: The Go-Busters are embroiled in the Super Sentai Strongest Battle. (Super Sentai Strongest Battle)
- 2021: The Go-Busters, among the first 44 Super Sentai, are embroiled in the Zenkaigers' conflict with the Kikaitopia Dynasty Tojitendo. (Kikai Sentai Zenkaiger)
