For references to Pinky and the Brain, see this page.
- The third issue of the miniseries Harley & Ivy has Harley Quinn engrossed in watching a cartoon titled Acromegliacs, which isn't shown on-panel, but the names of the main characters are Yucko, Rondo and Splat in reference to the Warner Siblings being named Yakko, Wakko and Dot, plus the theme song is an obvious imitation of the one for Animaniacs.It's time for Acromegliacs
And we're ugly to the max
We kinda look like cows with big lumps on our brows
We're Acromegliaaacs!
- Bolt: The pigeons that Bolt meets in New York are very similar to the Goodfeathers.
- Teen Titans Go! To the Movies: Starfire recognizes the Warner Bros. water tower as the home of the Warner Siblings, incorrectly referring to them as "the Animaniacs".
- Several episodes of ER contain characters with Animaniacs merchandise.
- An episode of New York News featured a Yakko costume character at a kid's birthday party.
- LEGO DC Super-Villains: One of the civilians in Smallville will occasionally mention that he likes to imagine the local water tower as the comfortable home for a family of orphaned cartoon characters.
- An event in Monster Prom has a cult try to come up with a theme song for their leader, Zoe, only to state that they blatantly ripped of the Animaniacs theme song and rejected it.
- Square Root of Minus Garfield: This strip
is a collection of Garfield panels accompanied by the lyrics of "I Am the Very Model of a Cartoon Individual", a song that Yakko performs in "H.M.S. Yakko".
- SCP Foundation: SCP-674 is a Zapper light gun for the NES that acts like a real gun if someone fires it at a character in a movie or a TV show. Its previous owner first discovered its unique properties when he was watching Animaniacs and fired it at Yakko during his performance of "Nations of the World." After Yakko regenerated, he wagged a finger sternly and warned him that the SCP Foundation was "going to get him" if he continued using the device in such a manner.
- In an episode of Console Wars, Greg and Dan see whether the SNES or the Sega Genesis had the better Licensed Game based on the show.
- The Nostalgia Critic has done several videos about the show, including a tribute that featured several cast members, one going over adult jokes in the show and one counting down his favorite sketches. Additionally, he has reviews the Direct-To-Video Film Wakko’s Wish.
- Batman: The Animated Series: In "Torch Song", when Bruce asks Barbara what she's doing that night, she replies "The same thing we do every night, Pinky." Bruce doesn't get the joke. (BTAS and Animaniacs had some of the same writers and crew.)
- The Duck Dodgers episode "Pig Planet", features Eager Young Space Cadet's niece and nephews, "Porko, Puerco and Sow" who are even voiced by Yakko, Wakko and Dot's voice actors.
- Freakazoid!:
- The first episode features a segment in which Yakko, Wakko and Dot sing a song called "Freakazoid and Friends" to the tune of the Animaniacs theme.
- "The Freakazoid" has a scene where Wakko randomly shows up after a person calls the titular character a wacko. He tells Freakazoid that he thinks Animaniacs is Steven Spielberg's favorite show. Then, the Brain shows up to argue that his show is better. Then, all three begin a big argument about it. When they address the problem to Steven himself, he wonders who these three characters are.
- MAD: One skit featuring Mickey Mouse as a Pest Control member has Pinky and the Brain among the mice and rats that Mickey catches.
- The Mask: One episode has Stanley meeting his favorite cartoon characters, the Goofalotatots: a skunk, a beaver, and a squirrel who are very obvious spoofs of Yakko, Wakko and Dot — and are actually voiced by Rob Paulsennote , Jess Harnell and Tress MacNeille.
- Robot Chicken:
- A sketch from "Kramer Vs. Showgirls" has Michael Moore interview Pinky, who reveals that the Brain's big noggin was the result of Paget's Disease. Pinky also reveals that he has a giant human ear on his back, a reference to the "Vacanti mouse"note .
- A sketch from "Eviscerated Post-Coital by a Six-Foot Mantis" features Pinky and The Brain going on a psychedelic trip. Maurice LaMarche reprised his role as The Brain for this sketch.
- A sketch from "Cheese Puff Mountain" features Yakko singing the Kama Sutra, parodying the "Yakko's World" and "All the Words in the English Language" sketches from the show.
- South Park: In "Cartman's Silly Hate Crime 2000", the juvie kids consider Cartman on their side after he says he doesn't like Animaniacs.
- Tiny Toon Adventures:
- In the Spring Break Special, the deer in the prologue is from Bumbie's Mom. In the same special, Pinky and the Brain make cameo appearances as two of the caged pets when Elmyra announces that she is going to catch the Easter Bunny, who she believes is Buster Bunny. (The epilogue to the special confirms this to be true.) The Warner siblings make a brief cameo as well, once again doing their literal Running Gag of being chased by Ralph.
- In "Night Ghoulery", Fifi is dressed like Dot in the opening credits. In the same special, Baloney and Mr. Director appear in "The Devil and Daniel Webfoot" sketch, where they are in line for the Devil's autograph. The Brain also makes a brief cameo in the "Frankenmyra and Dizzygor" sketch, and the gag credit for the special acknowledges his cameo.
