Mythology Gag / Resident Evil 6

• Leon and Ada's campaigns are full of gags towards 2 and 4.
  • Leon's first chapter in particular has him running into a rookie cop on the streets of Tall Oaks in the midst of a full-blown Zombie Apocalypse, at a gas station, no less. Sure enough, it's the cop's first day on the job as well. He doesn't make it, however.
• The Ustanak is pretty much a moving Mythology Gag to all the Implacable Man bosses of the franchise.
• Helicopters and their pilots still have a hard time. Main character driven or not.
• Jake and Sherry can pick up a revolver called Elephant Killer.
• When you FINALLY kill Derek Simmons, it ends with him impaled on a spire and oozing blood into a floor mosaic. When seen from above, the four massive puddles, interspersed with still-white tiles, creates a giant Umbrella Corporation symbol.
• Simultaneous bioterrorist attacks and outbreaks both in the U.S. and China was the original plan by Morpheus D. Duval of Resident Evil: Dead Aim in-universe 2002. Although by coincidence, Carla Radammes launches it eleven years later using a similar tactic Morpheus planned: airburst missiles armed with the virus and let it infect an entire city.
• Neo-Umbrella J'avo are inhuman monsters wielding guns and wearing armor and gas masks, just like the real Umbrella's Under Takers.
• Chris Redfield having PTSD mirrors the "It Came from Kijuju" ad campaign for Resident Evil 5, which focused on Chris suffering flashbacks to his time in Kijuju.
• You have to roam through Iluzija's lair, avoiding deadly ambushes, and kill it by shooting it in its open mouth. Very much like the fights against Yawn in Resident Evil: The Umbrella Chronicles.