Game Breaker / HoloCure

In your pursuit to save the fans, you'll come across several things that can be a massive help.

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Weapons

While most weapons are generally used to combine collabs, a few weapons in particular stand out for being quite powerful even on their own. In fact, 0.6's nerf to collabs have made certain weapons outright stronger on their own.

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• EN's Curse fires off curses that have a high chance to chain to another target. At max level, for every time the curse chains, its damage increases by 10% with no cap to how high it can go. Within a huge horde of enemies, this makes EN's Curse capable of reaching damage in the thousands quite easily. It's easily among the best choices for your final weapon late in a run, if you aren't using it for Eldritch Horror.
• Wamy Water stands out for being an exceptional weapon for crowd control, especially in the late game. At max level, the water spray knocks back enemies quite a bit and also stuns them for good measure, allowing for a lot of breathing room in the more difficult stages.
• CEO's Tears are a powerful supplement to damage output, firing off tears that deal damage quite rapidly. At max level, with a little bit of haste, the tears basically shoot endlessly, creating a strong damage supplement as a final weapon once all of your collabs have been assembled.
• Spider Cooking is not crazy powerful as a late-game pick like the abovementioned weapons, but it's one hell of a Disc-One Nuke. Its ability to protect from all sides is appreciated by most characters early on, especially those who, like Baelz, lack reliable starting weapons to do this job. At max level, it has knockback, and does a very good job at creating a pocket of relative safety around the character, especially when enchanted for size, hit rate or knockback. If all that wasn't enough, it's a component in not one, but two collabs that are Game Breakers of their own right, Jingisukan (a must-pick on all characters with healing synergies) and Eldritch Horror (a must-pick on almost all other characters due to its massive damage), so the characters that don't want to grab Spider Cooking as soon as it's available can be counted on one hand.

Collabs

• Super Collabs, introduced in 0.6, have taken the place of regular collabs as the Purposely Overpowered Infinity +1 Sword, dealing impressive damage and also providing incredible utility. They can only be crafted starting at level 50, and require a Golden Hammer alongside the Golden Anvil. Since the Golden Hammer only drops once, you can only have one per run. Since they also use up an item in its creation, this frees up another item slot for even more broken build potential.
  • Idol Live (Idol Concert + Idol Costume) sends out rapid bursts of glowsticks and music, reduces Special cooldowns by 30%, and adds in an effect that boosts all stats by 50% for 10 seconds after activating a Special. This is obviously useful for characters with very powerful specials, like Bae and Kobo, and those whose specials buff them in the first place, like Calli, turning them into juggernauts for the duration, or just for those with shorter special cooldowns that can maximize the buff's uptime like Gura or Miko. Another interesting note is that if the Super Idol Costume is used to create Idol Live, the super collab retains the super item's ability to use the Special twice despite not listing it in its description.
  • Jingisukan (Elite Cooking + Uber Sheep) takes the constant damage zones from Elite Cooking and adds in rapid HP regeneration when standing in the zones. It also boosts max HP by a massive 100 points, to further compound on survivability. This collab has absurd synergy with characters with healing synergies, including Fauna, Choco and Sora, ramping up their already high survivability and damage output through the roof. It also provides a hefty boost to characters building Piki Piki Piman, the power of which is based on HP.
  • Holy Fire (Dragon Fire + Gorilla Paw) combines the rapid fire flames with powerful fists and equally fast blue flames that fly all over the screen, on top of multiplying all damage dealt by 1.3 and nullifying the Crit rate penalty. This is the most general super collab, fitting all playstyles since no character will ever not need bonus damage.
  • Snow Queen (Snow Flower Sake + Sake) summons a screen wide blizzard that deals constant damage and freezes all enemies it touches, and also boosts critical rate by a static 20%, nullifying Sake's downsides. While it's most obviously meant for Critical Hit Classes, the usefulness of its freezing power in builds that value control over raw damage is not to be underestimated.
• Even after the nerfing of collabs in 0.6, a few still remain relevant:
  • Rap Dog (Idol Song + X-Potato) continuously throws potatoes all over the screen that cause all enemies hit to take 20% more damage, letting you kill much faster. While its damage has been decreased, the power of Rap Dog was never in its damage, but rather in its impressive debuff.
  • Eldritch Horror (Spider Cooking + EN's Curse), previously seen as an underwhelming collab, has been Rescued from the Scrappy Heap and buffed at the same time most others have been nerfed into the ground, making it now stand very far above the rest. Just about the only thing holding it back from being a must-have in every run is that it competes for one of its components with the powerful Super Collab Jingisukan, and its other component happens to be a Game-Breaker by itself.
  • Frozen Sea (Wamy Water + BL Book) has been slightly buffed instead of nerfed, which is not saying much considering its low damage. However, it remains a useful crowd control tool and a must-pick on Aki due to her debuff synergies.
  • Snow Flower Sake (Wamy Water + Glowstick) got to keep its damage output unchanged, in addition to carrying a 30% chance to freeze enemies in their tracks, creating some much needed breathing room.

Items

• Super items are Super-powerful versions of normal passive items and can greatly decide the run in your favour, but you'll have to be Super-lucky, because they only appear from HoloZon boxes.
  • If you're lucky enough to get the Super Super Chatto Time and combine it with the Greed stamp and Halu, you'll not only be picking up a ridiculously high amount of coins, you'll also be powered up to ungodly high levels with it as well, being easily capable of killing every single thing in the stage and hold yourself against the YAGOO horde for a good amount of time.
  • The Super Idol Outfit will make certain characters unstoppable if they manage to grab this because not only does it fully charge specials in roughly less than a minute, you get two uses of a Special off a single full charge.
  • The Super Gorilla Paw outright multiplies all damage dealt by 1.5, without the drawback of reduced critical chance.
  • The Super Energy Drink grants a massive 30% boost to Haste and 60% boost to Speed, without the drawback of reduced max HP, speeding your character up immensely.
  • The Super Credit Card halves the cost of upgrading items and doubles the spawn rate of anvils, and guarantees an anvil will appear every minute, giving it fantastic synergy with the Blacksmith's Gear. 0.6 reduced the discount rate to 40% (same as a level 5 normal credit card), but it doesn't affect its value.
  • Perhaps more than other Super items, the Super Chicken Feather can turn run around with 5 revives and on top of the usual effects, each one gives 20% Attack and 10% Speed, which is enough for most characters to turn things around.
  • The Super Hope Soda boosts critical damage by a hefty 50% without the drawback of increased Special cooldown, and also guarantees that every 10th hit is guaranteed to crit, making it amazing for characters with rapid-fire attacks.
• The Greed Stamp gives your default weapon a chance of yielding a Coin each time it hits an enemy. It's fantastic with multi-hit weapons like IRyS's, as the combo litters the stage with Coins, letting you line your pockets really quickly without even needing Halu! For bonus points, combine it with Supa Chatto Time, which can auto-collect any coins that drop. If you're really lucky and acquire a Super Supa Chatto Time (see above), which also permanently buffs Attack based on Holocoins collected, IRyS can reach a damage output almost comparable to that of pre-fix Mumei. The Greed Stamp was adjusted in 0.6 such that its base trigger rate is lower but has a higher chance of activation and higher coin yield on more damaging hits, so it now benefits any character, not just the rapid-fire ones.
• Blacksmith's Gear has become a must-get item for all runs. Just getting the item alone allow the use of normal anvils twice before they disappear, effectively giving the main benefit of a max level Credit Card for only one level. Leveling it up further increases the strength of enhancements, providing a much appreciated boost during endless mode/late-Stage mode. Combine with the Credit Card and watch as all your items and weapons max out faster than even with max level Glasses, allowing level ups to be used to boost up stats, and extra anvils to be put towards enhancements.
• The Kusogaki Shackles are a game changer of an item that, when fully leveled, completely negates the negative effects brought on by other items. This means that at the cost of one of your item slots you can use risky items like Injection Type Asacoco and Face Mask without having to worry about becoming a Glass Cannon, run Candy Kingdom Sweets without dropping your damage, or use Gorilla's Paw on [[Critical Hit Class]]es. In the right build, Kusogaki Shackles can essentially read "Increase your maximum health by 20, reduce damage taken by 30%, increase weapon damage by 25%, increase critical hit chance by 20%..." which is obviously an item you'd take in a heartbeat. Do note however, that it does not work on the Halu.
• The Beetle is a powerful item that boosts the damage potency of character skills by 100% at max level, increasing further by 1% per character level. With this item, certain character skills that deal damage become even deadlier (Aki's Belly Dance + Mukirose, Ollie's Zombie Jutsu, Moona's Lunar Construction + Moon Song to name a few), and can contribute to even higher DPS. Its potent power boost is well worth the difficulty in unlocking it (clear a stage with no character skills learned). While not all characters benefit from it equally, or at all, the very existence of this item is enough to turn some otherwise underwhelming characters, like Shion, into powerhouses.
• The humble non-super Gorilla's Paw provides the coveted damage multiplier effect, which is found on only a select few items, which tend to have crippling drawbacks. This includes the Paw itself, but the price of its power (a 20% drop to critical hit rate) is a non-issue for most characters, considering that at maximum level, the boost it provides (1.4 multiplier) is very close to being the equivalent of a crit on every single weapon hit. Only dedicated Critical Hit Classes should ever really pass on it... unless of course they're building Holy Fire, which completely negates the Paw's drawback altogether.
• The Candy Kingdom Sweets inflicts a negative damage multiplier of 0.75, which might not seem very good at first glance. In exchange however, it also grants up to a massive 60% boost to haste, greatly boosting attack speed for all weapons. Additionally, there is a 10% chance for every attack to deal an additional hit worth 33% of its base damage, which adds up very quickly. The greatly hastened rate of fire for all weapons more than makes up for the negative damage multiplier, and there are ways to get around it such as the Gorilla's Paw listed above. Like the Beetle, its incredible power is well worth the difficulty in unlocking it (level up haste 10 times in a single run).
• Halu, an item that boosts the spawn rate and strength of oncoming fans with a huge coin bonus, is generally a Difficult, but Awesome double-edged sword that can quickly end your run if you're way too cocky or have a less optimized build, but if your character setup and build is well optimized (especially if your character is focused on crowd control), you'll be able to slice through those buffed foes like bread while having more opportunities to increase your level and strength (especially if you have Study Glasses, especially with it's buff in 0.6) at a quicker rate. Some characters good with this include Mumei, Reine, and Roboco-san).
• The Weapon Limit shop upgrade limits the amount of weapons that can be gained through level-ups and HoloZon box drops, and at its max upgrade your character can only attack with her default weapon. While it can make the game more difficult as you have less capacity to obtain other weapons to expand your offensive options, in practice, you can narrow your level-up options very easily to optimize your character. You cap out on items and upgrades quicker so your level-ups will offer stat boosts sooner, too. This is also where the Solo stamp (gives a damage boost depending on the number of empty weapon slots, capping at +75% at max upgrade and 5 empty slots) and Piki Piki Piman, which also enhances the damage of the main weapon significantly, truly start shining.
• The Pacifist Stamp became a very powerful stamp after its buff in 0.6, granting it a chance to destroy enemy projectiles alongside the stun chance. Notably, it is capable of cancelling Mikodanye's infamous fire breath, and can easily destroy A-chan and Nodoka's Bullet Hell spam. Combined with a fast-shooting character like IRyS, Risu, and Reine, you have a very powerful tool to help you in later stages.
• The Marking Stamp is rather mediocre and unnoticeable when used on regular enemies, but it is an excellent stamp for boss killing. It makes the first attack from the main weapon mark an enemy, who takes up to 30% of the damage dealt to any other enemy. Said mark lasts permanently until the enemy dies, which combined with the fact that bosses always spawn with mooks, can massively amplify the damage dealt against them, allowing for faster kills.

Characters

• The healing-focused characters frequently give you the staying power to go very far in a stage, and it would take a lot to get overwhelmed.
  • Ceres Fauna's skills include Guardian Tree, which will attack enemies from the ground when you get healed (even if you're already at full health), Whisper which gives you gradual healing over time and layers of damage negation, and Sapling which spawns health-giving saplings for every enemy defeated to continuously proc Guardian Tree. And just in case you get surrounded, her ultimate will give her temporary invincibility. Fauna's base skills give her a near-endless supply of health, and that's before you account for other sources of healing or defense.
  • IRyS is another character who can casually tank and outheal every mob up until the 30 minute mark once you max out all of her skills, pick up some collabs that cover a lot of area for maximum chances of proccing her healing abilities, and push her health and critical hit chance as far as you can. 0.4 gave her a native critical chance increase to make her less reliant on random items and boosted the power of her Half-Demon skill. 0.5 buffs her by having her shots be aimable and its high multi-hit nature when awakened makes it a good greed stamp money printer. 0.6's changes made low attack coin milking unviable, but her weapon with enough attack is still effective at greed builds.
  • Tokino Sora has the key skill Idol Healing, which turns any healing into a pulse that damages foes in her vicinity. While her former game-breaking combo of Piki Piki Piman + Idol Wings (see in Currently Nerfed, below) that allowed her to rule Endless with an iron fist was removed from existence, 0.6 gave her new key items: Beetle to make Idol Healing go nuclear, and Jingisukan to provide a reliable source of constant healing. The result is a character with what amounts to an "Instant Death" Radius and a Healing Factor to recover from any injuries within seconds.
  • Yuzuki Choco starts out a little weak but quickly turns into an unstoppable juggernaut. Her healing directly translates into massive area damage (much more so than Sora, the last character to have a similar gimmick), and the result is a character that is almost impossible to take down while still outputting insane damage numbers. In case that wasn't quite enough, with one or two items to boost her crit rating, she can turn fans into her own minions, taking them out of the battle and turning them into even more damage output in one fell swoop.
  • Yozora Mel is a Friendly Neighborhood Vampire, so her skills are focused on Life Drain. Her toolkit is very synergistic: a skill that spawns food, another that temporarily buffs her and gives her lifesteal on attacks when she eats food, and the last one releases damaging bats when she lifesteals health. Lifestealing attacks are a very powerful thing and it ensures that Mel heals to full from basically any food, no matter how weak its effect (including her own... exotic cooking), but it's balanced around the fact that you're probably not eating food all the time... or are you? The super collab Jingisukan heals for 3 health every second, which is not much, but it counts as a food-based heal, allowing Mel to refresh Acerola Juice every second, essentially giving all of her attacks lifesteal, and releasing gratuitous amounts of bats in the process. With this build, Mel becomes Sora 2.0, essentially unable to die to anything until the YAGOO swarm grows powerful enough to kill her in fractions of a second before she can heal the damage off.
• Tsukumo Sana is a character that basically plays itself once you have acquired her unique skills (minus Astrology, which is not as important as the rest) and raised her basic attack to level 7. With her Awakened attack knocking away all enemies around herself and her Gravity pulses blasting and staggering everything on the screen, most enemies simply cannot even reach her, even if she just stands in place. This kit already gives you a good base and only gets stronger with other area-based attacks. In the rare cases she is actually overwhelmed, she can simply turn giant, becoming invulnerable, and reposition herself more favorably. She's the easiest character to earn the "Couch Potato" achievement with, which requires you to clear a stage without moving.
• Ouro Kronii's passives crank her Haste, ATK and SPD which makes her quite the Lightning Bruiser when paired up with defensive items to maintain her Full Health Bonus. If things get dicey, her Time Bubble can create openings to escape or the breathing room to mop up waves, and the same goes for her special.
• Hakos Baelz's skillset heavily relies on the number of weapons you picked up but once you upgrade them to the point where you max out her base skills and weapons she can craft collabs, you can easily obliterate bosses with her special. "Down Under" is a boon for later waves, as it applies to any weapon hit, and considering how many you can equip, you have a deceptively high chance to keep an enemy stunned. Boosting your critical chance to the fullest tier through stats ups and various items, on top dense waves in the later minutes of Bae's "RatNG" skill, ensures that "CRATical Hit" almost always procs, resulting in obscene amounts of damage.
• Even after her nerfs, Nanashi Mumei is still a fantastically powerful character. Her Civilization skill boosts her ATK up to 150% for every target on screen, ramping up her killpower in huge hordes, her Friend skill is an extra supplement to her high damage output, copying up to 2 of her weapons, and her Bloodthirsty skill is yet another sizeable ATK boost alongside HP restoration. Additionally, her previously unhelpful True Horror special was buffed in 0.6 to no longer delete pickups, but now grants her a Haste buff for 10 seconds equivalent to how many enemies were killed by the special, which can be a lot of Haste especially in the lategame.
• Roboco-san at first seems like a bit of a letdown with a measly peashooter ill-suited to dealing with large hordes and skills that don't provide much benefit at first. However her emphasis on leveling up means that with the right build she can soon snowball into insane levels of power. The Study Glasses getting a buff in 0.6 (which not only increases experience rate, but also slightly increases her power too) also makes her even more powerful. It can even get to the point where she can hold back the YAGOO horde for a considerable amount of time even with a fully leveled Halu.
• Aki Rosenthal is a character that feels like she should, by all means, not work. But she does. Boy does she ever. Aromatherapy combines with Mukirose for impressive amounts of damage over time to hordes despite Aki's lack of a traditional attack boost, and her auto-aim Aiks encourage the player to simply run in circles around a bunch of crippled enemies as they slowly die... all the while building up Belly Dance stacks just in case something does go horribly awry. Did we mention that she has essentially two panic buttons instead of one? Of which one can deal damage that puts most proper specials to shame, and the other not only slows enemies to a pathetic crawl while simultaneously brutalizing them with Mukirose punches, but also heals Aki in the process? For about ten seconds, she can just walk right up to the much-dreaded Nodoka spewing Bullet Hell everywhere and say "no, this is my battlefield".
• Nakiri Ayame, the dual Katana wielding Oni shows everyone why she is to be feared. With the right items after maxing out her main weapon, Ayame can slice and dice almost anyone to shreds in seconds especially when her "Spirit of the Oni" special is activated. Additionally, there's 40% chance that any defeated mobs will become "spirits" that will circulate around Ayame and deal damage to said mobs. Furthermore, her "Nakirium" allows Ayame to gain 20% bonus EXP within 120px, "Lady of Oni" buffs her speed per target killed and "Ayame Defense Field" can make Ayame invincible for 4 seconds after taking certain amount of hits. She is particularly strong on one-weapon runs since that allows her to take full advantage of her special and the impressive power of her main weapon.
• Akai Haato seems unassuming, but her main weapon is an Orbiting Particle Shield that provides 360 degree coverage. Combining this with the right stamps to unleash more projectiles and control enemies through stun (or knockback) means that most enemies can't reach her. On top of that, she has a whopping 30% damage reduction and passive healing. With a tanky build and a good amount of speed, she can evade the YAGOO swarm for an impressive amount of time by stunning the ones in close proximity. She is not half-bad in stage mode either, with Haachama's poisoned hearts doing a good job thinning out enemy hordes and melting bosses, Haato's resilience getting her out of sticky situations, and their monstrous Coexistence form making short work of the challenges neither of them can get through alone.
• Ayunda Risu is an incredible wave clearer with the rapid-fire nature of her attacks. Her "Deez" skill gives her main weapon a chance to deal damage equal to 25% of the enemy's max HP, letting her Nuts kill faster than its quick-but-weak hits would suggest. She also has "Nonstop Nuts", which causes the enemy to explode into a burst of nuts when killed, which deals multiple hits for even more damage. For even more carnage, Risu also has the "DLC" skill, which creates a clone of herself when Holocoins are collected 5 times, up to a maximum of 3. Yes, these clones will also throw Nuts, and yes, those nuts can also trigger "Deez"'s effect.. Combined with the Greed Stamp and Super Chatto Time, Risu can keep these clones up indefinitely and tear through hordes of enemies very quickly, which coincidentally also makes her an excellent money farmer.
• Kureiji Ollie has a ton of very strong abilities all crammed into a single character. She has an Awakened main weapon that is extremely strong and fantastic at abusing stamps due to its spinning nature. Simp of All Time boosts her haste to levels that only Kronii outmatches. Undeath not only gives her second chances at life, something that only Kiara could previously boast of, but also boosts her already impressive damage output even further while its maximum health debuff is active. Finally, like Aki, she effectively has a second panic button in the form of Zombie Jutsu.
• Kaela Kovalskia is a character focused on Gathering Steam, with her key skill "Material Grind" which gradually buffs the damage of all her weapons depending on how many mineral deposits (dropping from enemies) she has mined. She also has a skill that deals massive damage to a few enemies, but most importantly it has a chance to create an anvil. Pair her with an early Study Glasses, which also increases the damage of weapons based on levels gained, and her own Blacksmith's Gear, and a late-game Kaela can easily get collabs to shine with all their former glory if not moreso. Unlike other Gathering Steam characters, such as Roboco, Kaela does not have a weak early game thanks to "No Pressure", a damaging and slowing skill with an insane radius, best described as Spider Cooking on steroids, which Beetle can buff to utterly ridiculous levels.
• Following her buffs in 0.6, AZKi went from a fairly weak character to one of the best, if not the best, coin farmers in the game, beating out even IRyS. She comes with a decently strong early game with her "Encore!" skill, sending out a damaging wave every 7 seconds, growing in potency based on how many enemies she kills within those 7 seconds. She also has with "Virtual Diva" and "Performance", the former boosting her attack speed, the latter enhancing her movement speed and dodge rate. However, her main draw is none of these skills, but rather her main weapon, Diva Song, which when maxed out has a 75% chance to split into 2 musical notes that also pierce through enemies. As of 0.6, these sub-notes can also trigger Stamps, and crucially, each individual hit from this weapon deals much more damage than those from IRyS's rapid-fire beam. When combined with the reworked Greed Stamp (the output of which now depends on damage) and the Bomb Stamp, this results in massive amounts of coins. Played optimally, AZKi can easily farm millions of Holocoins in a single Endless run! As Diva Song also hits quite hard, AZKi is no slouch in Stage Mode, combining her great speed with potent killpower that rips through mobs easily.
• Apex predator of HoloEN Gawr Gura is one of the original queens of Endless and still holds up fantastically to this day. Her key skill is Shark Bite, which gives every hit a chance to reduce the enemy's defense (stacking up to 5 times, to a whopping 60%) and enemies marked this way may also heal Gura when defeated. The debuff is a multiplier, meaning that it scales well into the late game, and with just a bit of haste and the right rapid-fire collabs, applying 5 stacks consistently is child's play. Power of Atlantis traps enemies and also reduces their defense, and between that and Shark Bite, Gura can hit like a truck. Finally, Short Height gives her a fairly high chance to just negate damage and significantly boosts her speed, helping her dodge precarious situations (and kite YAGOO swarms on Endless). So she offers a mix of damage, battlefield control, healing and defense and each ability is potent enough to make her into a Master of All rather than a mere Jack of All Stats. Her only period of vulnerability is before she can acquire the collabs needed to make Shark Bite truly shine, but her special, a Disc-One Nuke that doesn't do very much in the late game, will do wonders to carry her through any Early Game Hell.

Former Game Breakers, currently nerfed

• Collab weapons were Purposely Overpowered, but since they can be acquired fairly early into a run if you know what you are doing, 0.6 sought to reduce their impact to make them more of an Infinity -1 Sword, in some cases making them arguably weaker than their components. Prior to the nerf, here are some collabs that saw widespread use which are no longer anywhere as powerful as they used to be:
  • Bone Bros (EN's Curse + Cutting Board) rapidly shoots out highly damaging sword beams in the front and bullets in the back, making for a potent waveclearing tool.
  • I'm Die, Thank You Forever (Holo Bomb + X-Potato) sticks a ticking time bomb to an unlucky mook, and killing said mook creates a humongous screen-filling explosion. Depending on your haste, you can stick multiple bombs and detonate them for a chain of screen-wide nukes all over the place!
  • MiComet (Psycho Axe + Elite Lava Bucket) drops down a powerful meteor that explodes into a massive pool of lava, continuing to burn enemies. Notably, Baelz's Special can make this fire rapidly for absolute devastation.
  • Dragon Fire (Plug-in Type Asacoco + Fan Beam) is an extremely fast stream of fire that quickly vaporizes any enemy in front. It used to scale amazingly well with base damage upgrades from the anvil, but the calculation was changed to bring fast-hitting weapons more in line with their slower counterparts. However, it remains highly sought-after due to being a component of the Super Collab Holy Fire.
  • Elite Cooking (Spider Cooking + Elite Lava Bucket) doesn't deal a lot of damage on its face, but covers a wide area and has a tremendous hit rate, making it a weapon of choice for idols who have a chance to trigger certain effects on hit, such as Gura, Miko and Bae. These same characteristics initially made it scale extremely well with weapon upgrades, but like Dragon Fire, it suffered from 0.6's changes in damage calculation in that regard. However, it's also a component of the Super Collab Jingisukan.
• In the earliest builds of the game, the Plushie used to be a supreme Game-Breaker by providing invulnerability frames whenever the character got hit, with no cooldown. This was insane on literally every talent, and particularly so on Ninomae Ina'nis due to her Harmless Takodachi being able to connect with her without dealing damage while still counting as enemies for the Plushie's purposes, retriggering the invincibility frames before the previous ones could run out, creating a loop that ensured complete invincibility.
• While Kronii on the whole is still strong, her Time Bubble is no longer the Game-Breaker it used to be. Before a haste cap was implemented on it, the bubbles could start overlapping if enough haste (around 200%) was achieved, allowing Kronii to escape a YAGOO swarm indefinitely.
• For a while, Tokino Sora was the queen of Endless due to the synergy between her special, which heals her, and Piki Piki Piman, which at that point would recharge the Special gauge when the character took hits, this allowed for an infinite loop of Sora reactivating her special before it could run out and ensuring that nothing short of a One-Hit KO could put an end to her. These shenanigans were put to an end in 0.5 when the chance of her special healing her on hit were halved. In addition, in 0.6 Piki Piki Piman's effect was changed to something entirely different (although the Spicy Seafood Udon meal from HoloHouse has a similar effect to its former description).
• Calliope Mori was seen as one for some time after a significant buff gave her the ability to clear massive hordes in basically a single scythe swing with her Death ability, allowing her to easily obliterate early stages. Since then, several nerfs over time and the introduction of stages with much tougher hordes against which Calli struggles to get her Disaster Dominoes going have taken her firmly out of Game-Breaker territory, making her more of a Crutch Character.
• Nanashi Mumei was an absurd Game-Breaker in the early days of Holocure due to two oversights: History scaling endlessly instead of capping out like intended, which let her accumulate absurd amounts of ATK in Endless runs, and Friend suddenly going insane the second she reached 100% haste, firing massive volleys of every weapon Mumei has, flooding the entire field in powerful collabs. Both were subsequently nerfed. As of 0.6, Mumei is once again capable of scaling endlessly, but only at a rate of 1% ATK per 100 kills, which is far slower than her original rate and no longer capable of keeping up with Yagoo growth.
• The Solo Stamp used to provide a damage boost of up to 40% to the character's main weapon for each empty slot, capping out at +200% with 5 empty slots. This obviously made it a be-all end-all stamp on one-weapon runs, but beyond that, getting it early enough into a regular run could also allow a character to snowball out of control right past the Early Game Hell. For 95% of a stage's duration, there was basically no reason to run the normal Attack stamp as even with a single empty slot, the Solo Stamp would outclass it. The Solo stamp was nerfed into the ground in 0.6, going from 40% to 15% damage per slot (with a ceiling of 75%). While the update introduced a few new tools for one-weapon runs to compensate (most obviously the reworked Piki Piki Piman), the Solo stamp is no longer something every single build will pick up on sight unless it drops 3 minutes before the final boss.