Please sort new titles alphabetically to avoid double-entries.
- PandoraHearts: A cheerful, 15-year-old boy tries to figure out how he became the main character in Alice in Wonderland.
- Alternatively: A teenage boy who is secretly 25 tries to get his daddy's approval with his useless servant and a bunny girl. Alice in Wonderland references are everywhere. Similar to a story written by CLAMP, minus the noodles.
- Alternatively: A 15-year-old boy is actually 25 years old and not actually a boy, but a rabbit, which is actually a stuffed toy, which is actually a monster from a world-altering hell pit. His current "boy" body actually belongs to a historic hero who is actually the villain.
- Pani Poni Dash!: An eleven-year-old college graduate and her mopey, long-suffering pet teach an eccentric high school class in Japan.
- Panty & Stocking with Garterbelt: A nympho and a glutton fight the demonic personifications of everything disgusting in a city under siege using their frilly things that turn into energy weapons. Gainax ensues and the biggest mindfuck in the studio's history ends it.
- Or: Two siblings use their various undergarments to fight off the forces of evil. The art design could easily be confused for The Powerpuff Girls.
- Or: A group of people known for making some of the weirdest anime known to man get drunk. This is the result.
- Paradise Kiss: Stiff and dull student is abducted by technicolor-haired aspiring fashion designers. Flamboyant jerkass dandy makes her his muse. The author loves Vivienne Westwood.
- Paranoia Agent: A girl has a period cramp, and because of this her dog dies. Tokyo is destroyed as an indirect result.
- Or: A dog dies. Weird shit happens. At some point, the Blob attacks.
- Parasyte: A teenager's hand turns into a sentient penis. They fight aliens.
- Peach Girl: A tan girl falls in love.
- Pecola: A flightless bird Funny Animal goes around town playing pranks on the other Funny Animal townspeople. Every character is comprised of cube shapes.
- Penguindrum: A hat threatens to let a girl die unless her brothers can find something for it. Nobody really seems to know what it is they're actually looking for.
- Perfect Blue: A pop idol becomes an actress, but her manager isn't sure that she should. At least one character is insane.
- The Pet Girl of Sakurasou: Kindhearted Cat Lover receives a Idiot Savant girlfriend.
- Pet Shop of Horrors: Mysterious Bishōnen runs evil pet shop with poor customer service and no return policy.
- Phantom Thief Jeanne: Two thieves compete to steal cursed artwork.
- Piano: A high-school girl helps her best pal find a boyfriend. She plays piano too. Sometimes.
- A Place Further than the Universe: Teenage girls go south for the... summer? One of them saves a lot of money for the trip, but never gets around to spending it.
- Planetes: Garbage collectors IN SPACE!.
- Alternatively: Garbage collectors discuss morality and associated political issues.
- Or: Garbage collector is nearly driven insane by trauma, seeks to make something of himself. Terrorists and a romantic side-plot almost screw everything up for him.
- Please Save My Earth: Babysitter knocks charge off balcony. They get engaged.
- Please Teacher!: Alien teacher marries a narcoleptic high-school student.
- Pluto: German robot seeks information from Robo-Hannibal Lecter and Saddam Hussein. Is thwarted by evil teddy bear.
- Pokémon: The Series: Boy walks the Earth with his collection of compactified combat critters while being stalked by a redhead, a runaway heir to the world's biggest fortune and a talking cat.
- Pokémon Mystery Dungeon: Explorers of Time and Darkness: An amnesiac kid with psychic powers teams up with a different geek and a hyperactive girl. They go out to defeat a perverted dragon and get a scale.
- Pokémon Mystery Dungeon: Beyond Time and Darkness: Said amnesiac psychic kid causes a time paradox.
- Pokémon: The First Movie: Clone gets the Clone Angst and wants revenge on the world. He stops after nearly killing somebody.
- Pokémon 2000: A collector of rare things accidentally triggers severe climate change. The fate of the world is saved through a pun.
- Pokémon 3: Little girl who loses her parents uses a magic alphabet to replace them. The alphabet accomplishes this by providing a fire-breathing beast for the dad and brainwashing someone else's mom.
- Pokémon: Mewtwo Returns: Former genocidal maniac attempts to become a martyr. The main protagonist finally meets his arch-nemesis and declines to battle him.
- Pokémon 4Ever: Nature Spirit escapes capture by Time Travelling into the future, only to be captured anyway.
- The Legend of Thunder: A generator draws electric Mons toward it, and a legendary beast is caught in the confusion.
- Pokémon Heroes: Two thieves try to steal strange gem. Two voluntary shapeshifters who can make themselves invisible fight back.
- Pokémon: Jirachi: Wish Maker: Magician makes a wish to summon a beast with the powers over the earth. He gets an Eldritch Abomination instead.
- Pokémon: Destiny Deoxys: Aliens pay a visit and are mistaken for invaders.
- Pokémon: Lucario and the Mystery of Mew: A tree is collapsing and a desperate struggle is underway to save it. Meanwhile, two cats and a mouse play in a tree.
- Pokémon: The Mastermind of Mirage Pokémon: A scientist creates life through blatant hacking. Fans instead debate the morality of replacing voice actors.
- Pokémon Ranger and the Temple of the Sea: Young girl becomes a mommy at the age of ten. A pirate demands sole custody.
- Pokémon: The Rise of Darkrai: Two Kaiju with powers over the entire universe threaten the existence of a single town. Meanwhile an Eldritch Abomination tries to convince people that he is not evil.
- Pokémon: Giratina and the Sky Warrior: Another Kaiju is ticked off at the previous two for trashing its home. But first it needs a hedgehog with an attitude in order to leave home.
- Pokémon: Arceus and the Jewel of Life: The above three Kaiju's parent awakens due to their fighting. It's God and it's enraged at the humans about its missing jewelry.
- Pokémon: Zoroark: Master of Illusions: A Mama Fox goes on a shapeshifting rampage after her baby gets kidnapped.
- Victini and the Black Hero: Zekrom/Victini and the White Hero: Reshiram: One Film For The Price Of Two
- Pokémon: Kyurem vs. The Sword of Justice: A hero-in-training heads out to slay a vicious dragon. Everyone is happy when he loses.
- Pokémon: Genesect and the Legend Awakened: Heavily-armed, violent scientific experiments try to conquer Central Park. They stop after several flowers die.
- Pokémon: Diancie and the Cocoon of Destruction: A bejewelled creature brings about mass murder as she tries to find a deer to make a jewel look better.
- Pokémon: Hoopa and the Clash of Ages: A genie's Superpowered Evil Side decides to remake Destroy All Monsters. God Himself eventually says "knock it off."
- Pokémon: Volcanion and the Mechanical Marvel: An Obviously Evil politician and an Oxymoronic Being fight over a robot girl's heart. Sadly, it is not a Romantic Comedy featuring robosexuals.
- Pokémon: I Choose You!: A ten year old Walking the Earth fights a rainbow god and is executed by firing squad.
- Pokémon: The Power of Us: A town is choked with Deadly Gas until a large fan is turned on.
- Pokemon Mewtwo Strikes Back Evolution: Clone gets the Clone Angst and decides to end the world. He stops when a kid throws himself into the line of fire and dies.
- Pokémon Adventures: A bunch of kids walk the Earth, keep befriended animals in portable habitats and battle with them. Has a more serious tone than the above. A plant with glasses draws some of it.
- Pom Poko: A group of forest animals become eco-terrorists, with unpleasant consequences.
- Ponyo on the Cliff by the Sea: A fish drinks human blood and transforms into a little girl; her endeavor to reunite with the boy she loves inadvertently leads to the whole town reverting to the Cambrian era.
- Popee the Performer: A sociopathic clown boy frequently abuses a dog. His dad is there too and he's really creepy. It's early 2000's TV CGI, and the sound design will worm its way into your brain. Also, everyone dies a lot.
- Pop Team Epic: The adventures of two girls with one facial expression and 48 voice actors between them.
- Porco Rosso: A pilot becomes the other white meat, then beats up pirates and a pushy American.
- Italian fascists don't like it when pigs fly. Harmless pirates and a lounge singer are involved.
- Potemayo: Daily life of a boy and his new pet.
- Alternatively, the daily life of a Huge Schoolgirl and her wild, laser-firing new pet.
- Powerpuff Girls Z: Transvestite Satan gets less screen time than in the American series, and this is a bad thing.
- Prétear: A girl is hired by a group of Bishōnen to help fix changing weather patterns. Though it's actually more complicated, they appear to turn into clothes.
- Pretty Cure: Magical Girls use shounen fighting tactics and magic to defeat evil forces.
- Pretty Face: Through the magic of plastic surgery, a teenage boy comes back from the dead as his crush's twin sister.
- Pretty Sammy: Pre-teen becomes magical girl. Hates it because her skirt's too short.
- The Prince of Tennis: Skill at sport bestows ability to defy physics and commit genocide against the dinosaurs.
- Or: Hitting a fuzzy rubber ball better than anyone else is more important than grades, a future job, or one's physical well-being.
- Or: A sports anime where the opposing players are way more interesting than the protagonists.
- Or: Ho Yay: The Sports Manga.
- Princess Jellyfish: A cross dressing man tries to save a group of geeky girls' apartment building.
- Princess Mononoke: A dying man helps a misanthropic woman save her home from governmental development.
- Or: Exiled prince shouts at everyone. They don't listen.
- Princess Nine: Going against tradition, nine high school girls form a baseball team and compete against the boys in the national baseball tournament.
- Princess Princess: Three boys improve the school's morale by crossdressing.
- Princess Principal: Five schoolgirls are tasked with espionage between two warring superpowers, with lots of frilly dresses, steam, and gravity-defying rocks. One of them is a princess.
- Princess Resurrection: A princess and her siblings find some... interesting ways to avert a Succession Crisis.
- Princess Tutu: If you simply make a wish, fairy tales do come true. Giving them happy endings is a lot harder.
- A duck, a girl who can't dance, and a magical girl ballerina princess are the same person. She/they heal people with the power of dance.
- A duck dances strangers' problems away because she can't confess her love to a boy with no pants.
- The Nutcracker and Swan Lake do coke lines off a Magical Girl duck ballerina's back. Drama ensues.
- A dead man tries to write a tragedy. His characters revolt.
- A duckling confronts a raven.
- Project A-Ko: Girls with lettered names fight off an alien invasion when they aren't fighting each other.
- Promare: The Earth is going to explode in the near future, so the biggest leader of the world wants to gather as many people as he can and migrate them to another planet they can terraform. It's up to a bunch of firefighters, and one rebellious young man, to prevent that migration from happening.
- The Promised Neverland: The top students at a school for genius children decide they'll stop attending. One of them is caught, however, and is forced to attend a school for children who are even more gifted.
- Prunus Girl: Girl claims to be boy, but may in fact actually be a girl. Male lead is confused.
- Psychic Squad: Man plays babysitter to three prepubescent weapons of mass destruction while an 80-year-old fights for their romantic affection.
- Psycho-Pass: Futuristic police department hunts down mentally unstable people and makes them explode. Many members of the department have serious mental issues themselves. They are opposed by a pretentious bookworm with a mullet.
- Psyren: Teenagers with psychic powers travel to the future to change the past.
- Puella Magi Madoka Magica: A Weasel Mascot recruits young girls to fight Eldritch Abominations. Recruitment involves Faustian deals.
- Alternatively, being a Magical Girl is... traumatizing.
- Alternately: A Magical Girl travels through time to convince her best friend to refuse jewelry.
- Alternatively: The anime you already know everything about.
- Alternately: Girl fights off suicidal, soul-crushing depression by getting in touch with her spiritual side.
- Alternatively: Like a "Thomas Covenant" novel by Stephen Donaldson, but with Magical Girls! (and shorter and less depressing)
- Alternately: Several middle schoolers sell their souls for magic Faberge eggs and die horribly.
- Puella Magi Madoka Magica The Movie: Rebellion: God attempts to save her beloved angel. Said angel refuses salvation, remakes the world in her own image.
- Teenage girl overthrows God and becomes Satan so her best friend/girlfriend can live a normal life.
- Puella Magi Kazumi Magica: Amnesiac magical girl finds out she's a clone of a dead one created to defy the Weasel Mascot.
- Puella Magi Oriko Magica: Well-Intentioned Extremist magical girl kills magical girls to try and stop a world-ending Eldritch Abomination.
- Puella Magi Tart Magica: The story of Joan of Arc: Magical Girl Edition.
- Magia Record: Puella Magi Madoka Magica Side Story: A Magical Girl tries to find her missing sister and ends up dealing with a supremacist cult run by eleven-year-olds.
- Puni Puni☆Poemi: Magical girl with severe mania uses a dead fish to save planet from aliens who watched our porn.
- RahXephon: Boy meets girl. Boy is trapped in Human Alien time-slowing orb of death for many years. Boy uses Mecha against his will to kick copious amounts of ass.
- Neon Genesis Evangelion on its meds. Half the time. Roughly.
- Lost continent of Mu is sick of those Atlantis jerks getting all the attention, shows world what for with giant clay dolls powered by singing.
- Rakugo Tennyo Oyui: Wannabe comedienne and friends go back in time to fight demons.
- Ranma ½: An extremely masculine boy/girl attracts loads and loads of fiancées, girlfriends, and psycho stalkers. Of both genders. Completely against his/her will. Hilarity Ensues.
- Teenaged boy goes swimming with panda against tour guide's advice and loses his manhood, delighting and/or horrifying everybody he knows.
- Rave Master: Some people travel the world to find four stones and destroy a bunch of other stones.
- Ray the Animation: Girl makes like Black Jack (who shows up) while looking for her eyes; her replacements have X-Ray Vision.
- Read or Die (OVA): Shy bookworm must kill Beethoven and other historical figures with paper.
- Read or Die (Manga): Said shy bookworm has her ex's best friend trying to beat her to the library for stealing said ex from him.
- Read Or Dream (Manga): Three blood-sisters use their powers to solve book-related cases in Hong Kong.
- R.O.D the TV: Blood-sisters protect a famous author from the bookworm's former boss.
- Reborn! (2004): A baby trains a kid to be a Mafia boss by repeatedly shooting him in the head.
- The Record of a Fallen Vampire: Dhampyrs chase vampire. Then there are aliens.
- Record of Lodoss War: A typical D&D party teams up to save the world from an evil witch that wears purple lipstick.
- Recovery of an MMO Junkie: When a guy and a G.I.R.L. meet online, nerd love happens.
- Re:CREATORS: A normal boy, some mangakas, a librarian, a warrior, a villain and a mecha driver try to prevent the end of the world planned by a girl with a military uniform.
- Red Garden: Four dead girls fight middle-aged men in suits.
- Red Line: A technical pacifist wants to join the galaxies most illegal and deadly street race. This makes chaotic evil cyborgs angry. Enough Scenery Porn to make some officially declare every frame should be a screenshot.
- Can aptly be described as "Whacky Racers tripping on LSD."
- The Red Ranger Becomes an Adventurer in Another World: A Sentai hero ends up in the wrong genre.
- Reign: The Conqueror: Alexander the Great is persuaded not to take a trip to India. Man-thongs are common attire.
- Revolutionary Girl Utena: A girl enrolls in a mysterious academy where fencing is practically a way of life and everyone has issues.
- Or: Jumped-up preps duel each other in order to gain metaphysical powers to solve their problems instead of learning common sense and proper communication skills.
- Or: A pervert with a mullet encourages pretty teenagers to solve their problems through metaphorical violence and pop philosophy for no particular reason.
- Or: Girl insists she is straight despite spending the entire series fighting with Bishōnen boys to remain engaged to a girl.
- Adolescence of Utena: Same thing, only with more mind screw and lesbianism. Also, the heroine turns into a car because the director wanted to.
- Requiem from the Darkness: Darker and Edgier Scooby-Doo in Feudal Japan.
- Ringing Bell: Sheep Bambi pulls a Face–Heel Turn as an attempt at revenge.
- The Rising of the Shield Hero: Four otakus become legendary heroes, and the one without an actual weapon is treated like shit just for showing up.
- Rizel Mine: Boy likes older women, but he's forced to be with a younger girl. She cries Nitroglycerin. In the end, the younger girl was an older woman all along.
- Japanese teen is forced to marry a little girl by the government to keep her from crying despite not being a lolicon. No one sympathizes with him for not wanting to consummate their marriage.
- Robot Carnival: Robots reenact Fantasia.
- Robotech: First giant human aliens attack the Earth. Then their normal sized human bosses attack the Earth themselves. Finally, their older own enemies, alien quasi snail/insectoids sometimes taking human form, attack the Earth.
- Or American company decides to combine three unrelated series into one and stop the originals from reaching the United States.
- Rocket Girls: A Japanese company can't build a rocket capable of lifting a full grown man into space, so they use a teenage girl instead.
- Rockman EXE: Boy surfs the internet, saves the world.
- Shooting Star Rockman: Boy gets on radio, saves the world.
- Rolling Girls: In a world where super-powered vigilantes solve land disputes, four ordinary girls travel across Japan on motorcycles, helping people in exchange for their hearts.
- Romeo × Juliet: Crossdressing rebel falls for dictator's son.
- Alternately: Shakespeare IN SPACE with flying horses, starring William Shakespeare himself (kind of).
- Rosario + Vampire: Boy stumbles into an Extranormal Institute and becomes popular. Come for the panties, stay for the plot.
- Alternately: A mother gives her sickly daughter a blood transfusion. Through a complicated series of events, this causes the death of Satan.
- Alternately: An ordinary human boy with a psychotic split personality, a vampire girl who also has a psychotic split personality, a lustful teen genius, a Sugar-and-Ice Personality stalker, a racist flower child, and an ethical succubus decide to go fight an Eldritch Abomination.
- The Rose of Versailles: Sparkly, alcoholic Bifauxnen protects the Queen of France from everything except her own passions.
- Roujin Z: A parable on health care and the elderly.
- Alternately: A nursing student tries to help an elderly couple go to the beach, but the military won't let them.
- Rozen Maiden: Seven sisters fall asleep in the Victorian era and awaken in the 2000s. They begin to congregate around a reclusive Japanese boy while searching for their father, never once thinking that he might have died of old age.
- Seven wind-up girls with Verbal Tics compete to become the perfect Victorian ideal of maidenhood by killing their sisters and ripping out their hearts for daddy. Meanwhile, a shut-in ignores real girls to play with toys.
- Rurouni Kenshin: In Meiji-era Japan, a former assassin fights evil with a backwards sword.
- Alternatively: A swordsman who likes to wear purple is attacked by Marvel Universe look-a-likes.
- Scryed: A rebellious man with a powerful arm fights a stoic guy with a killer robot named after his dead dog. Otherwise, pretty much X-Men with more rainbows. The theme song can only be described as 'Japanese Mexican salsa'.
- The Sacred Blacksmith: Katanas Are Just Better: The Anime
- The Saga of Tanya the Evil: Nihilistic, atheist salaryman is pushed into a running train by one of the employees he fired, and gets reincarnated into a sadistic warlord loli in World War I. Philosophical and metaphysical arguments ensue.
- Saijou no Meii: A Manchild slices open children, and gains friends and followers for doing so.
- Or, the exact same as the author's previous manga, but with a different silly subject.
- Saikano: Boy has sex with dead robot. Everyone dies.
- Sailor Moon: Overdeveloped girls in underdeveloped uniforms live vicariously through past-life regression.
- Sailor Moon: An overdeveloped teenage girl becomes a superhero and gains powers over stock footage. She meets other girls with similar powers over stock footage. They all die in the end.
- Sailor Moon (DiC): A strangely told abridged version of the story where the main characters have different names, the girls teach you life lessons, and everything is funnier.
- Sailor Moon R: Overdeveloped teenage girl gains her stock footage powers back, becomes a single mother and gets locked in a custody battle with aliens. She blows up a tree, but its not canon.
- Sailor Moon S: A group of mad scientists rip peoples' hearts out. A lesbian couple appears and nearly kills our protagonist. She receives a more impractical outfit from a cup.
- Sailor Moon Super S: The daughter of the overdeveloped teenage girl falls in love with a horse.
- Sailor Moon Stars: Overdeveloped teenage girl gets an even more impractical outfit from another cup and becomes an adoptive sister. All of her friends die again.
- Pretty Guardian Sailor Moon: A group of high school girls marked by their matching plastic jewelry can never quite be sure if they're all friends or not.
- Saint Seiya: Five young men wearing magical armor fight for an heiress who is later revealed to be a goddess.
- Or: Orphaned children are forced to endure Training from Hell and do a girl's bidding.
- Saint Seiya Omega: You got HeartCatch Pretty Cure! in my Saint Seiya!
- Saint Seiya: Saintia Sho: You got Sailor Moon in my Saint Seiya!
- Saint Young Men: Jesus and Buddha celebrate their divine bromance by moving to Japan and renting an apartment together.
- Saitama Chainsaw Shoujo: A boy breaks up with his girlfriend. She goes Chainsaw Crazy.
- Saiyuki: Four guys are sent west in a very small jeep by a hermaphroditic deity. Hilarity Ensues.
- Saki: Ahem, er, so twenty Ambiguously Gay schoolgirls walk into a mahjong bar...
- Sakura Gari: Rōnin in Taishou Era Japan comes to work for screwed-up noble family, gets sexually harassed, eats Korokke
. Also, everyone is crazy.
- Sakura Trick: Cast Full Of lesbians make out. That's pretty much it actually...
- Samurai Champloo: A tavern waitress cons a ronin and a bandit into following her around Japan, looking for a guy she can only recognize by smell. They do it all to the tune of a hip-hop soundtrack.
- Or: Admittedly a Very Loosely Based on a True Story version of Feudal Japan.
- Samurai Flamenco: A delusional male model fights petty crime as a superhero.
- Samurai 7: A retelling of a classic Japanese tale, only this time with the heroes facing down an evil emperor and Humongous Mecha.
- Sandland: Satan's son looks for water.
- Sankarea: A boy turns a girl into a zombie. And then dates her.
- Sasami-san@Ganbaranai: Japanese Mythology "reimagined" by a drugged-out, incestuous hikikomori.
- Sasami: Magical Girls Club: Witch disguised as chef and her talking rabbit recruit five outcasts to become witches themselves. Some of them look familiar.
- Sayonara, Zetsubou-Sensei: A teacher copes with his dissatisfaction with society by encouraging people to kill themselves. Hilarity Ensues.
- Or: Large Ham teacher is suicidally depressed. His entire class falls for him. He's the sane one.
- Or: I'M IN DESPAIR!: The Anime.
- School Days: A young man gets himself into a twisted Love Triangle... with heavy emphasis on "twisted".
- High school harem show happens without a Chaste Hero. Consequences ensue.
- School Rumble: Reformed delinquent turned closet mangaka falls heavily in love with a ditzy girl with wiggly pigtails. Comic misunderstandings and love dodecahedrons result.
- Or: A tale of love and morons that tends to wander off course.
- Science Fell in Love, So I Tried to Prove it: A Love Confession gets a very bad case of Derailed for Details.
- Science Ninja Team Gatchaman: Ninja superheroes battle evil organization led by masked freak with weird secret.
- Or: Five kids with bad hair and bellbottoms change into bird costumes to fight evil.
- Scott Pilgrim Takes Off: A guy from Toronto falls in love with a girl from New York and loses in the first fight derailling the script. The rest of the cast, including the evil exes, gets more screetime as a result.
- Scrapped Princess: Girl was chucked off a cliff by her parents because they didn't want to deal with her sweet sixteen.
- Seitokai Yakuindomo: Boy is forced to join the student council at a former all-girls school while the President and secretary (along with just about every other girl) make all of the sex jokes.
- Or: Hentai protagonist decides he'd rather be in a Slice of Life.
- Seiyu's Life!: An informative look at the voice-acting industry where the main characters only spend half their time voice-acting.
- Sengoku Basara: Historical Samurai do almost nothing that they did in real life and fight obvious evil with the power of Engrish, hot blood, explosions and cameo appearances based on a video game.
- Seraph of the End: A young man enlists in the army so he can go look for his very thirsty long-lost childhood friend and give him something to drink.
- Serial Experiments Lain: Middle school girl gets computer so she can go online and stay there.
- Girl is not using a computer. Girl is using a computer. Girl is a computer.
- In a high-tech world, everything is intriguing and nothing makes sense.
- Girl is not using a computer. Girl is using a computer. Girl is a computer.
- Servamp: High school boy gets lazy vampire roommate when all he wanted was to adopt a cat, decides to fight a Mood-Swinger villain who's trying to get his siblings' attention by killing them.
- The Seven Deadly Sins: A group of rebels with an evil-sounding name fight a group of knights with a virtuous-sounding name.
- Seven of Seven: A girl becomes her own best friends and gets through middle school by dressing up as a sentai heroine.
- The Severing Crime Edge: Boy meets girl. Boy cuts girl's hair. Boy is charged with protecting girl from insane murderers.
- Or: The only one who can save a girl with Rapid Hair Growth is her barber.
- Sgt. Frog: A quintet of easily-distracted aliens plot to take over the Earth. They are regularly thwarted by a teenaged girl and her nerdy brother.
- Alternatively: A loser, a psycho, a pedophile, a creepazoid and a decent human being try to become dictators. They fail every time.
- Shadow Star: A cute girl finds an adorable star-shaped friend during summer vacation. Things go downhill... fast.
- Shakugan no Shana: An Ordinary High-School Student becomes the servant of a hot-headed demon hunter after a monster erases him and his friends from existence.
- Shaman King: Every 500 years, Native Americans have fun making people kill each other with dead people so they can control God.
- Shattered Angels: A Japanese teenager with an increasingly messed-up family tries to murder three expies and a blonde girl (each of whom can summon magic mecha) because he thinks that's what his dead brother probably wanted. The blonde one falls in love with him and helps him in his quest. He falls in love with one of the expys. His brother wasn't dead and he gives up eventually.
- Shigurui: Two crippled men hate each other, a sadistic noble makes them fight to the death, and the audience learns a lot about internal human anatomy.
- Shiki: House, Wilson, and the Rail Tracer take on an army of vampires, no one really wins. Everyone's hair is extremely silly.
- Shimoneta: A series that pokes fun at at censorship, by having a pervy girl in a bedsheet draft a generic guy to co-found an ero terrorist group called "SOX," to rebel against the oppressive Japanese government.
- Shin Mazinger: That giant robot with a lot of firsts gets to destroy monsters by turning into a fist!
- Shinesman: Man joins a company and is recruited to fight evil with office Supplies. Hilarity Ensues.
- Shingu: Secret of the Stellar Wars: Aliens attack earth with Giant robot acorns, unraveling a millennia-old Masquerade. More importantly, a Tsundere can't decide whether she likes the narrator or the mysterious transfer student.
- Shoujo Shounen: A boy dresses up as a girl, joins the entertainment business, gets exposed, and finds love, in no particular order. Each volume showcases a new Wholesome Crossdresser!
- SHUFFLE!!: God and Satan are now BFF's and move their families in together. Nobody really notices. However, their daughters fight over a human high school student that will one day succeed one of them. Hilarity ensues.
- Shugo Chara!!: A schoolgirl who hates her personality uses magical eggs to break out of her shell.
- OR: Some kids fight corporate evil with the help of magic eggs.
- Shut Hell: A psychotic murderer is taught how to read and write by a kid trying to protect a bag of rocks from his dad.
- Silent Möbius: A very special team of policewomen battle monsters.
- Silver Spoon: A burned-out academic high-achiever attends an agricultural high school in Hokkaido.
- Simoun: Lesbian Space Muslims[/Catholics?] doodle in the sky. Stuff blows up.
- Sister Princess: Unlucky Everydude gets exiled to an island to live with a dozen or so inhabitants that all attach themselves to him in borderline-illegal ways.
- Sketchbook ~full color'S: Shy girl becomes involved in local art club, draws scenery. Also, there's a Canadian.
- Sket Dance: Gintama set in high school.
- Skip Beat!!: Unlucky Childhood Friend attempts to take revenge upon the man who dumped her by beating him at his own game...show business.
- Slam Dunk: A guy proclaims himself to be a genius on a sport he hates out of spite to impress the girl of his dreams.
- Slayers: Hot-headed sorceress/thief teams up with empty-headed swordsman to fight evil.
- Or: A greedy, vain, violent, underdeveloped sorceress. An idiotic, easily-distracted swordsman. A girl who thinks she's in a Magical Girl anime and is very destructive as a result. A broody mutant who tends to be dark at best. They're the heroes.
- Or alternately - The quest for food and treasure is key, but keeps being interrupted to save the world.
- Sleepy Princess in the Demon Castle: Girl seeks out methods for a good night's sleep. Millions die as a result.
- So, I Can't Play H!: A harem series, where the fate of two worlds depends on our pervy protagonist, who unwittingly makes a contract with a redheaded shinigami.
- Sola: "A skywatching guy with a Delicate and Sickly albino sister meets a mysterious girl being hunted by the Highlander, who has connections to an Elegant Gothic Lolita who hangs out in garbage cans eating riceballs." (- Description taken from the show's page.)
- SoltyRei: Grumpy old man forms Odd Friendship with Robot Girl whose life he saved.
- Sonic the Hedgehog: The Movie: Speedy mammal and his friends fall for the oldest trick in the book, end up fighting mammal's Evil Doppelgänger.
- Sonic X: Illegal immigrants must stay hidden from the authorities, though they aren't very good at it. Later, they go home, only to find that they have to fight aliens that think they're doing the right thing but are really destroyers of worlds.
- Or: A group of animals have adventures with a clingy, rich kid that has some serious issues to work out.
- Season 3: The worst possible outcome of Meet the In-Laws in any form of media.
- Sound of the Sky: A young girl joins the army so that she can learn to play the trumpet. She is assigned to a platoon situated in a Spanish-inspired town. They spend their time fixing a tank and waiting for the phone to ring.
- Or: Treason Apologism: The Anime
- Or: After the End, K-On Expies are sent to the front lines; nothing happens. Amazing Grace always works.
- Soreike! Anpanman: A living loaf of bread fights crime and feeds himself to the hungry. His archenemy is a germ from space.
- Soul Eater:
- A scythe and the daughter of a scythe attend an Extranormal Institute and fight a snake witch.
- Death employs children to fight a mad god, and watches while they end up going mad in the process. Author is pop culture fan who does it for the lulz and the cool over, and over again.
- A girl with self-esteem issues and her Jerk with a Heart of Gold non-boyfriend fight insect-related or pop culture-related villains with their dysfunctional friends, including an arrogant ninja (and his non-girlfriend) and a boy with severe OCD who eventually goes mad. Other characters include a klutzy teacher who smokes a lot and a teenager with an ambiguous gender.
- Or "Tim Burton: The Anime."
- An apprentice of the Grim Reaper gets superpowers when she hears music played on the piano by her shiny magic stick, which she may or may not be in love with.
- Or: A teenage guy and a girl in his class go do stuff and she catches a rare disease from him.
- Straight from its Laconic: The world starts reeking of insanity, and a bunch of Almighty Janitors try to stop its spread.
- A girl hits many things with a book, including her own weapon, a ninja runs around shouting, and the son of Death falls in love with symmetry while two pistols complain.
- The SoulTaker: The hero dies in the first scene. His little sister has multiple personality disorder, except worse. There's also a guy with a toothache.
- Nurse Witch Komugi: Earth has to be cured of its supernatural ills by an amateur cosplay idol.
- Genesis of Aquarion: Robot powered by orgasms fights every fairy tale ever.
- Shirokuma Cafe: A bunch of zoo animals hang out in a cafe.
- Space Adventure Cobra: A Jean Paul Belmondo look-a-like teams up with scantily-clad women and travels through space to look for treasure. He often encounters an evil bald guy made of glass.
- Space Battleship Yamato: A World War II-era battleship is equipped with a really powerful gun and sent off into space to fight alien invaders.
- Space Patrol Luluco: The most Trigger thing that Trigger ever Trigger'd.
- Or: Middle school student becomes a contortionist and falls in love because her father didn't pay attention to his breakfast. Crossovers ensue.
- Space Runaway Ideon: Everyone dies over the course of 39 episodes and a movie... especially in the movie. By the man himself.
- Speed Grapher: Man who hates his superpower travels with technically-prepubescent girl. Romance develops.
- A combination of drugs and fetishes gives superpowers to many people who probably should not have them.
- Speed Racer: Racing heavily modified cars is Serious Business.
- Spirited Away: A ten-year-old girl helps and is helped by a spa employee with partial amnesia after her parents' bad table manners nearly cause her to fade from existence.
- A-ten-year old girl works in a bathhouse. Not like that, you pervert.
- Alice's Adventures in Wonderland in a bathhouse.
- Greedy family pigs out and leaves their grade-school daughter stuck with the bill. She works hard to pay it off and falls in love with a river.
- Spy X Family: A superspy invents a fake family in order to investigate a prestigious member of society who's suspected of trying to start a war. Little does he know that his wife is a Professional Killer and their daughter can read minds. Cue Slice of Life hijinks.
- Squid Girl: Sgt. Frog with a moe-ized squid.
- Or: A one-girl invasion of Earth is sabotaged by her own adorableness.
- Or: A Japanese series about a tentacle monster trying to take over the world, with a cast largely consisting of young females and with almost every episode taking place on a beach.
- SSSS.GRIDMAN: Amnesiac kid who sees funny clouds in the sky uses Transformers technology to fight giant monsters created by a lonely girl.
- Star Driver: A boy swims across ocean because he was late to school. He proceeds to become the Galactic Pretty Boy and pilot a giant robot which fights other giant robots powered by libido. Lots of hot blood and faaaaaaabulousness ensues.
- Starship Operators: Reality TV meets Embedded Reporting... IN SPACE!
- Steam Boy: A boy's father is killed for a new power source that he invented. He turns out to be not so dead. London freezes.
- Steel Angel Kurumi: Android in maid outfit is very overprotective of her priest-in-training master.
- Stitch!:
- Madhouse's two seasons (Stitch! and Stitch! ~The Mischievous Alien's Great Adventure~): An Okinawan girl lives with a chaotic alien, helping the alien get good deeds to get his wish to become the most powerful being in the universe granted. Also, there's youkai and other aliens.
- Shin-Ei Animation's season (Stitch! ~Best Friends Forever~): The girl and the alien move to a big city while a tall alien woman wants to capture a power cell within said alien. Also, there are more aliens.
- The Story of Saiunkoku: A girl agrees to marry an emperor in order to get him to rule his country properly.
- Str.A.In.: Strategic Armored Infantry: Sibling rivalry on an intergalactic scale.
- Strawberry Marshmallow: Obnoxious narcissist seeks attention from an implied pedophile.
- Strawberry Panic!:
- Members of a girls-only Absurdly Powerful Student Council engage in a Love Dodecahedron. The only men involved are those in the audience.
- Glorified beauty pageants are serious business. Add in a bit of Gayngst and lesbians for extra flavor.
- Maria Watches Over Us without the subtext.
- Stray Little Devil: A high school girl gets pulled into a spirit world and turned into a devil. Hilarity and Les Yay ensue.
- Strike Witches: Lesbians from all over the world strap airplane engines to their legs in order to fight aliens. Fans largely discuss clothing choices.
- Sugar Sugar Rune: An overly shy princess and her tomboyish best friend are cute witches. They go to the Human World to make guys fall in love with them, then about half way through things get worse.
- Summer Wars: A computer programmer, his "girlfriend" and her extended family fight a supervirus.
- Or: Computer whiz responds to a spam email; the spambot steals his password for Animal Crossing: The MMORPG.
- Sunday Without God: A girl buries dead people.
- Super Dreadnought Girl 4946: A boy routinely helps his girlfriend fight alien monsters by letting her eat him.
- Super Lovers: 13-year old boy wonders why his 21-year old brother doesn't want to have sex with him.
- Super Robot Wars Original Generation: Divine Wars: Scientist warns of alien invasion, makes his own team to stop them. Mecha otaku turned pilot and his team stop him. Then it turns out the scientist was right.
- Super Robot Wars Original Generation The Inspector: Beings from different dimensions come to invade us. Android with a stuttering problem decides to help us.
- Superior: Guy teams up with his girlfriend (and some other people) to hunt down his girlfriend, who he doesn't realize is his girlfriend. Deals with racism.
- Suzuka: Ordinary High-School Student becomes a world class sprinter to impress the title character, who hates him for being a more socially awkward stand-in for her dead ex-boyfriend.
- Sweet Blue Flowers: Cool upperclassman basketball player picks up a rebound but fails to score.
- Sword Art Online: A well-renown genius tries to keep his small, fragile world from coming to a brutal end, much to the displeasure of its other inhabitants.
- Sword of the Stranger: Swordless samurai murders drug addicts.
- Symphogear: Magic Idol Singer sings while fighting Eldritch Abominations.
