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* ''Literature/TheLaundrySeries'': Main protagonist Bob Howard's best friends, and roommates at the start of the series, are a gay couple nicknamed Pinky (CampGay) and the Brain (StraightGay).
[[AC: Video Games]]
* In ''Videogame/EscapeFromMonkeyIsland'', examining a dead rat leads Guybrush to say "What are we going to do tonight? Try to take over the Caribbean!
[[AC: Video Games]]
* In ''Videogame/EscapeFromMonkeyIsland'', examining a dead rat leads Guybrush to say "What are we going to do tonight? Try to take over the Caribbean!
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* ''Literature/TheLaundrySeries'': ''Literature/TheLaundryFiles'': Main protagonist Bob Howard's best friends, and roommates at the start of the series, are a gay couple nicknamed Pinky (CampGay) and the Brain (StraightGay).
[[AC: Video [[AC:Video Games]]
* In''Videogame/EscapeFromMonkeyIsland'', ''VideoGame/EscapeFromMonkeyIsland'', examining a dead rat leads Guybrush to say "What are we going to do tonight? Try to take over the Caribbean!
* In
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[[AC: Western Animation]]
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* In ''VideoGame/InfiniteCraft'', "Pinky and the Brain" is a possible crafting recipe.
* A late Season 2 episode of ''WesternAnimation/{{Grossology}}'' is titled "Pinkeye and the Brain".
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** A sketch from "Eviscerated Post-Coital by a Six-Foot Mantis" features Pinky and The Brain going on a psychedelic trip. Creator/MauriceLaMarche reprised his role as The Brain for this sketch.
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** A sketch from "Eviscerated Post-Coital by a Six-Foot Mantis" features Pinky and The Brain going on a psychedelic trip. Creator/MauriceLaMarche reprised his role as The Brain for this sketch.sketch.
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* ''WebVideo/BumReviews'': In the review of ''WesternAnimation/KungFuPanda'', Chester A. Bum describes the character of Master Shifu as "A mousie who looks like Pinky and the Brain's lovechild."
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* ''WebVideo/BumReviews'': In the review of ''WesternAnimation/KungFuPanda'', ''WesternAnimation/KungFuPanda1'', Chester A. Bum describes the character of Master Shifu as "A mousie who looks like Pinky and the Brain's lovechild."
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%% Image selected via crowner in the Image Suggestion thread: https://tvtropes.org/pmwiki/posts.php?discussion=1452266899092104700
%% https://tvtropes.org/pmwiki/crowner.php?crowner_id=fc17zbjw
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[[quoteright:350:[[WebAnimation/CampCamp https://static.tvtropes.org/pmwiki/pub/images/campcamp_pinky_0.png]]]]
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[[quoteright:350:[[WebAnimation/CampCamp https://static.tvtropes.org/pmwiki/pub/images/campcamp_pinky_0.png]]]]
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[[AC:Literature]]
* ''Literature/TheLaundrySeries'': Main protagonist Bob Howard's best friends, and roommates at the start of the series, are a gay couple nicknamed Pinky (CampGay) and the Brain (StraightGay).
* ''Literature/TheLaundrySeries'': Main protagonist Bob Howard's best friends, and roommates at the start of the series, are a gay couple nicknamed Pinky (CampGay) and the Brain (StraightGay).
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* ''WebAnimation/IdolCorp'': Roca Rourin's backstory, as revealed on her debut stream, consists of being summoned by a pair of Pinky and Brain expies [[ItMakesSenseInContext from a rock pet game]].
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* ''Webvideo/TheNostalgiaCritic'', when reviewing ''Film/ThePurge'', had to deal with a rumor that Pinky and the Brain were splitting. It even led to an animated segment where the mice had an argument, featuring the voices of Rob Paulsen and Maurice La Marche themselves!
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* ''Webvideo/TheNostalgiaCritic'', when ''WebVideo/BumReviews'': In the review of ''WesternAnimation/KungFuPanda'', Chester A. Bum describes the character of Master Shifu as "A mousie who looks like Pinky and the Brain's lovechild."
* ''WebVideo/TheNostalgiaCritic'':
** When reviewing ''Film/ThePurge'', the Critic had to deal with a rumor that Pinky and the Brain were splitting. It even led to an animated segment where the mice had an argument, featuring the voices of Rob Paulsen and Maurice La Marchethemselves!themselves!
** The Critic has reviewed the ''WesternAnimation/PinkyElmyraAndTheBrain'' spin-off.
* ''WebVideo/TheNostalgiaCritic'':
** When reviewing ''Film/ThePurge'', the Critic had to deal with a rumor that Pinky and the Brain were splitting. It even led to an animated segment where the mice had an argument, featuring the voices of Rob Paulsen and Maurice La Marche
** The Critic has reviewed the ''WesternAnimation/PinkyElmyraAndTheBrain'' spin-off.
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* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': In "The Ending of the End - Part 2" after Twilight's return to form, Pinkie asks, "What are we gonna do, Twilight?" Twilight replies, "The same thing we do every time, Pinkie: Try to save the world!"
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* ''WesternAnimation/{{MAD}}'': One skit featuring WesternAnimation/MickeyMouse as a [[FurryConfusion Pest Control member]] has Pinky and the Brain among the mice and rats that Mickey catches.
* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': In "The Ending of the End - Part 2" after Twilight's return to form, Pinkie asks, "What are we gonna do, Twilight?" Twilight replies, "The same thing we do every time, Pinkie: Try to save theworld!"world!"
* ''WesternAnimation/RobotChicken'':
** A sketch from "Kramer Vs. Showgirls" has Michael Moore interview Pinky, who reveals that the Brain's big noggin was the result of Paget's Disease. Pinky also reveals that he has a giant human ear on his back, a reference to the "Vacanti mouse"[[note]]a lab mouse who had been seeded by cow cartilage cells, causing the growth of a cartilage structure resembling a human ear[[/note]].
** A sketch from "Eviscerated Post-Coital by a Six-Foot Mantis" features Pinky and The Brain going on a psychedelic trip. Creator/MauriceLaMarche reprised his role as The Brain for this sketch.
* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': In "The Ending of the End - Part 2" after Twilight's return to form, Pinkie asks, "What are we gonna do, Twilight?" Twilight replies, "The same thing we do every time, Pinkie: Try to save the
* ''WesternAnimation/RobotChicken'':
** A sketch from "Kramer Vs. Showgirls" has Michael Moore interview Pinky, who reveals that the Brain's big noggin was the result of Paget's Disease. Pinky also reveals that he has a giant human ear on his back, a reference to the "Vacanti mouse"[[note]]a lab mouse who had been seeded by cow cartilage cells, causing the growth of a cartilage structure resembling a human ear[[/note]].
** A sketch from "Eviscerated Post-Coital by a Six-Foot Mantis" features Pinky and The Brain going on a psychedelic trip. Creator/MauriceLaMarche reprised his role as The Brain for this sketch.
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[[AC: Video Games]]
* In ''Videogame/EscapeFromMonkeyIsland'', examining a dead rat leads Guybrush to say "What are we going to do tonight? Try to take over the Caribbean!
* In ''Videogame/EscapeFromMonkeyIsland'', examining a dead rat leads Guybrush to say "What are we going to do tonight? Try to take over the Caribbean!
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[[AC: Web Animation]]
* ''Webanimation/CampCamp'' had in one episode a mouse with a pinky finger for a head and another with an enlarged brain labeled "taking cartoons literally".
[[AC: Web Video]]
* ''Webvideo/TheNostalgiaCritic'', when reviewing ''Film/ThePurge'', had to deal with a rumor that Pinky and the Brain were splitting. It even led to an animated segment where the mice had an argument, featuring the voices of Rob Paulsen and Maurice La Marche themselves!
* ''Music/PostModernJukebox'' [[https://www.youtube.com/watch?v=OqMs9WsJg2k covered the show's theme]]... while featuring Rob Paulsen and Maurice La Marche as the mice in "human outfits", working as bartenders.
* ''Webanimation/CampCamp'' had in one episode a mouse with a pinky finger for a head and another with an enlarged brain labeled "taking cartoons literally".
[[AC: Web Video]]
* ''Webvideo/TheNostalgiaCritic'', when reviewing ''Film/ThePurge'', had to deal with a rumor that Pinky and the Brain were splitting. It even led to an animated segment where the mice had an argument, featuring the voices of Rob Paulsen and Maurice La Marche themselves!
* ''Music/PostModernJukebox'' [[https://www.youtube.com/watch?v=OqMs9WsJg2k covered the show's theme]]... while featuring Rob Paulsen and Maurice La Marche as the mice in "human outfits", working as bartenders.
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[[AC: Western Animation]]
* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': In "The Ending of the End - Part 2" after Twilight's return to form, Pinkie asks, "What are we gonna do, Twilight?" Twilight replies, "The same thing we do every time, Pinkie: Try to save the world!"
* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': In "The Ending of the End - Part 2" after Twilight's return to form, Pinkie asks, "What are we gonna do, Twilight?" Twilight replies, "The same thing we do every time, Pinkie: Try to save the world!"
