History Main / YoureInsane

*** PlayedForLaughs in "[[Recap/StarTrekDeepSpaceNineS05E19TiesOfBloodAndWater Ties of Blood and Water]]" when Weyoun 5 drinks a shot of poisoned kanar just to demonstrate how Vorta can't be killed with poison.

* ''VideoGame/MetalGearSolid2'':

* ''Neo VideoGame/{{Contra}}'' has many moments of these in spades:

** As the incensed Vera and her fellow nobles argue about her act of [[spoiler:using them to fulfill her own vendetta]] in Chapter 30, Alan tells her that before he would have said her grandfather would be ashamed of her, but given everything they've learned about [[TheButcher his actions]] against the Mogriffs, he might have been completely mad, just like Vera herself. Vera [[ShutUpKirk replies that they're the only ones mad for not even trying to fight]] before [[spoiler:she breaks free from her Samurai Khan escorts in a final attempt to attack Metalbeak]].

* In ''ComicBook/TheTransformersDrift Empire of Stone'', Ratchet says this to Hellbat during his OmnicidalManiac-flavored MotiveRant. Hellbat doesn't even blink.

* ''Fanfic/ShadowsOverMeridian'': Elyon has this reaction in Chapter 10 when [[KnightTemplar Caleb]] declares that Kage must be killed to stop Phobos, especially since he's making this statement literally ''right after'' Elyon just said that she's trying to [[MustMakeAmends make amends]] and peace with Kage.

* ''Literature/SinisterSixTrilogy'': In ''Spider-Man: Revenge of the Sinister Six'', Spider-Man calls [[BigBad the Gentleman]], a novel-only villain, insane. The Gentleman retorts that he's not insane at all -- "[[CardCarryingVillain just evil]]."

* The former page quote came from ''ComicBook/ThePunisherMAX'' where Wilson Fisk utters this to newly hired hitman Bullseye. More or less summing up his first impressions of him.
* In ''ComicBook/RedRobin'' Tam Fox accuses Tim of being crazy after she's kidnapped by the League of Assassins and his infiltration of the group makes her think he's an assassin as well. He doesn't really correct her about his mental state but he does make it clear he's not a killer or on the League's side.
* In the ''Franchise/SpiderMan'' novel trilogy ''[[Literature/SinisterSixTrilogy Revenge of the Sinister Six]]'', Spider-Man calls [[BigBad the Gentleman]], a novel-only villain, insane. The Gentleman retorts that he's not insane at all -- "[[CardCarryingVillain just evil]]."
* In the ''ComicBook/{{Superman}}'' story arc ''ComicBook/KryptonNoMore'', super-villain Radion gets this reaction from Superman when he explains his master plan: he wants to cause a meltdown in all the world's nuclear reactors because he thinks the resulting Armageddon will lead man to the next level of evolution. Many will die. Many will become twisted mutations, but some will become supermen. And he will rule them. Superman's reaction is understandable:
-->'''Superman:''' Great Galaxies... the man's '''INSANE!'''
* In ''ComicBook/SupermanVsTheAmazingSpiderMan'', when [[Characters/MarvelComicsOttoOctavius Doctor Octopus]] finally discovers [[Characters/SupermanLexLuthor Lex Luthor]]'s real goal [[spoiler:(destroying the world)]], he blurts out: "Dear Lord -- he's mad!"
* In ''ComicBook/SinCity: A Dame to Kill For'' Dwight calls Ava insane after [[spoiler:she reveals her having manipulated him into murdering her husband for her]]. Ava's retort sums up very well where this trope can fall flat.

* The ''Film/{{Transformers}}'' live-action movie follow-up comic ''Reign of Starscream'' had this chilling exchange [[spoiler:right before Starscream murders her]]:
-->'''Elita-One:''' You're insane!\\
'''Starscream:''' No... I'm ''in charge''.
* Used in ''ComicBook/{{Nextwave}}'', but the BigBad's logic doesn't even try to make sense.
* In an issue of ''ComicBook/TheTick'' comic, the [[MadArtist art-themed villain]] the Impressionist is called crazy by his roommate. (At the time, the Impressionist was trying to eat a paint omelet.) Impressionist's retort?
-->'''The Impressionist:''' I am not crazy! I am an artist! Was Creator/{{Michelangelo|Buonarroti}} crazy? Was [[https://en.wikipedia.org/wiki/Pierre-Auguste_Renoir Renior]] crazy? ''Was [[Creator/VincentVanGogh Van Gogh]] crazy?'' [[NotHelpingYourCase OK, bad example]], but still...
* ''ComicBook/XMen'':
** During his first clash with the team in ''ComicBook/UncannyXMen'' #124, Arcade is told he's insane. His reply? "Crazy as a loon. Been that way for years."
** [[ComicBook/XManCounterX Towards the end of his solo run]], after becoming somewhat... ''strange'' and taking up the mantle of a mutant 'Shaman', [[ComicBook/XMan Nate Grey]] gets this, word for word. His entirely unfazed response? "Probably."
** From a side-story to the ''ComicBook/AvengersVsXMen'' crossover, in response to a MotiveRant:
--->'''Colossus:''' You're insane.\\
'''[[spoiler:Magik]]:''' Oh, thank you! Thank you! I knew eventually you'd understand.
* From ''ComicBook/SonicTheComic'' Robotnik's right hand man Grimer says this to Robotnik after Chaos absorbs the Chaos Emeralds;

* ''ComicBook/JudgeDredd'':
** In "The Day the Law Died", the mad-as-a-nuthouse [[TheCaligula Chief Judge Cal]] is called out on being an insane dictator numerous times. He was liberal with the death sentence to anyone who brought this up.
** When the formerly-human Judge Death [[SelfMadeOrphan executed his own mother]] by hurling her off a cliff, she shrieked that he'd gone completely mad. When he carried out the deed, she changed her accusation to YouMonster.
%% This is a zero context example. Please do not unhide until further context has been added. * ''ComicBook/BlakeAndMortimer'': This is Mortimer's eventual reaction to [[spoiler:Septimus]] in ''Recap/The YellowM''. Said character [[Berserk Button does not take it well]].

* ''ComicBook/IronMan:'' In ''Fatal Frontier'', Iron Man says this to an AlternateUniverse Characters/DoctorDoom after hearing the man describe his latest plan. Doom isn't fazed.
-->'''Doctor Doom:''' I'd be insane if I couldn't achieve it. As it is, I am merely ambitious.
* ''ComicBook/TheTransformersDrift Empire of Stone'': Ratchet says this to Hellbat during his OmnicidalManiac-flavored MotiveRant. Hellbat doesn't even blink.
-->'''Hellbat:''' Why? [[AtLeastIAdmitIt Because I admit to enjoying it?]] I don't need a war to hide behind.

* Creator/DashiellHammett's ''Literature/TheDainCurse'' concludes with one of the most effective "You're insane"s in literature.
* ''Literature/AlexRider'':
** Alex Rider says this to Herod Sayle, Dr. Grief, Sarov, Damian Cray, Julia Rothman, Nikolei Drevin and Winston Yu.
** ''Scorpia Rising'': A captured french agent says this to Razim when he explains his plans to create a unit for measuring pain. Razim [[InsultBackfire calmly states that a little bit of madness is important for scientific research]].
** ''Russian Roulette'': Yassen Gregorovich breaks into Vladimar Sharkovsky's house, and plays the title game with himself to decide if he should live or die. When Sharkovsky calls him mad, Yassen tells that he is what Sharkovsky made him, and then guns him down.
* In the ''Literature/ArtemisFowl'' short story "[=LEPrecon=]" Julius Root is tricked into a human settlement (which is magically forbidden by Fairy law) by his [[CainAndAbel evil brother Turnball]], he calls him insane. Turnball's reply is "No. What I am is tired. Tired of being chased across the globe by my own brother. [[LampshadeHanging The whole thing is too melodramatic]]."
* ''Literature/HarryPotter'':
** In ''Literature/HarryPotterAndTheGobletOfFire'', Harry comes out of the maze and Mad-Eye Moody [[spoiler:who was actually Barty Crouch Jr, who up until then Harry had respected and sought advice from, drags Harry off to his office so he can gleefully tell him how he had orchestrated the entire scheme and would now have the honor of killing Harry for Voldemort.]] Harry sums this up by telling him that he's crazy.
** A more mild example in ''Literature/HarryPotterAndTheOrderOfThePhoenix'' when Hermione says, ''"'Are - you - insane?'"'' in response to hearing that Harry's half-thought out plan for talking to Sirius involves breaking into Umbridge's office to use her fireplace.
* In ''Literature/TheFountainhead'', Ellsworth Toohey beats his victim to the punch:
-->'''Keating:''' Ellsworth... you're...\\
'''Toohey:''' Insane? Afraid to say it? There you sit and the word's written all over you, your last hope. Insane? Look around you. Pick up any newspaper and read the headlines. Isn't it coming? Isn't it here? Every single thing I told you?
* In ''Literature/TheDresdenFiles'' novel ''Literature/DeadBeat'' Dresden calls [[BigBad Cowl]] insane after learning of his plan to [[AscendToAHigherPlaneOfExistence become a dark god]]. This causes Cowl to briefly pause to consider the question, noting that if he ''were'' insane, than he might be unable to tell. This provides a parallel to when the question of whether Dresden would know if he was insane came up.
* In ''Literature/ThePictureOfDorianGray'', Alan Campbell calls Dorian Gray mad after [[spoiler:having been asked by Dorian to help dispose of Basil Hallward's body]].
* "You Don't Have to Be Mad...", a short story from the ''Literature/DiogenesClub'' series by Creator/KimNewman. Psychic detective Richard Jeperson investigates a clinic run by [[MeaningfulName Dr. I. M. Ballance]] which is turning people into functioning psychopaths (some of whom are implied to be infamous politicians and entrepreneurs of TheEighties). Dr. Ballance gives a MotiveRant over how Britain has always used mad people to achieve greatness, and how one day his madness will [[TakeOverTheWorld spread across the world]].
-->"I suppose it would be redundant to call ''you'' mad?" Richard ventured.\\
Dr. Ballance giggled.

* ''Literature/JourneyToChaos'': [[Literature/LoomingShadow Mr.15 explains his]] EvilPlan to Eric, which involves brainwashing, cloning, familicide, and Eric realizes that he is at the mercy of a madman. [[spoiler: He uses this as part of his IShallTauntYou.]]
* ''Literature/MassEffectAnnihilation:'' When Annax discovers who the villain is and why they did what they did (a bunch of salarians pulled a prank on them years ago [[note]]admittedly, one that nearly killed them.[[/note]]), she declares "you're insane", then adds that while it sounds [[LampshadeHanging like a line from a stupid vid]], the culprit really is out of their mind.
* ''Literature/ShadowOfTheConqueror'':
** Sain is completely unprepared for [[HamToHamCombat how intense things get]] between the main characters when he overhears a conversation about whether Daylen will TurnOutLikeHisFather.
--->'''Daylen:''' Trust me, if I do, [[DrivenToSuicide I'll kill myself]].\\
'''Ahrek:''' No, Daylen, if you truly become anything like your father, ''I'' will kill you.\\
''[beat]''\\
'''Daylen:''' [[SincerityMode Thank you. You're a better friend than I thought.]]\\
'''Ahrek:''' You're more than welcome.\\
'''Sain:''' You two are completely insane!
** Ahrek says this to [[spoiler: Daylen, [[MyGrandsonMyself after his identity is revealed]]]], while Lyrah provides [[YouMonster some moral support]].
* In the original novel of ''Film/TheLastKingOfScotland'', a British tabloid newspaper interviews a psychiatrist on [[TheCaligula Idi Amin's bizarre behaviour]] and their conclusion is spelled out in the headline: "HE'S MAD--IT'S OFFICIAL."
* ''The Devils Of D-Day'' by Creator/GrahamMasterton. The protagonist responds this way when offered a DealWithTheDevil. The demon making the offer just laughs. "Insanity is a human word which almost always describes the activities of devils."
* ''Literature/VillainessLevel99'': Pretty much everyone's reaction when Yumiella tells them what she did to get her level so high. This includes hunting monsters in the forest as a preteen, going alone into dungeons meant for parties, wearing magic equipment that boosts experience gains rather than offering any protection, and using a monster-summoning flute over and over to kill the summoned monsters for experience. She, not understanding the norms of society, doesn't realize why they are shocked.
* ''Literature/TheChroniclesOfDorsa'': The deathless king gives Joslyn an offer to [[WeCanRuleTogether rule the world with him]]. She scoffs at the idea, saying only madmen like him want that. Naturally, he brushes this off.

* In ''Film/{{Beauty and the Beast|2017}}'', this is Belle's [[SurprisinglyRealisticOutcome rather realistic]] reaction to Beast asking her out for dinner ''after'' locking her up in her father's place.

--->'''Valerie''': And just when I thought we had enough crazy here…\\
'''Nataline''': I'm not crazy for wanting to keep the world safe.\\
'''Valerie''': Then let me rephrase: for attacking someone you don't know… you're insane!

* ''WebVideo/BackstrokeOfTheWest'': Rather than Obi-Wan telling Anakin: "Then you are lost!", the GagDub has Ratio Tile telling Allah Gold: "Friend you are crazy!"

-->'''Rocko:''' You idiot! You almost got me killed! What's the matter with you?! You risk your life to get back to that chick and give her that blasted pebble! You're crazy! You're insane! You're… you're ''AMAZING!'' (''laughs'')

-->'''Jack Napier/The Joker:''' ''[{{laughing|Mad}}]'' Antoine got a little hot under the collar. ''[{{laugh|ingMad}}s]''\\

'''Lex Luthor:''' That is a three syllable word for any thought too big for little minds.

* Creator/JohnWoo's ''[[Film/BrokenArrow1996 Broken Arrow]]'' does it as well.

* ''Film/IndianaJonesAndTheTempleOfDoom'': Indy is about the cut the rope bridge with everyone still on it.[[note]]Just before, he told Short Round (in Chinese) to wrap his wrist with one of the ropes, with Short Round telling Willie that they're "going for a ride".[[/note]]

'''Short Round (a.k.a. "Shorty"):''' [[YouNoTakeCandle He no nuts.]] [[DepartmentOfRedundancyDepartment He's crazy!]]

** ''Film/GoldenEye'': Bond gives a KirkSummation to Janus/[[spoiler:Alec Trevelyan aka 006]] on his plot to ruin the world, though [[spoiler:006]] [[ShutUpKirk chews him out]] on his FailureHero tendency to lose allies on missions, his FatalFlaw for women[[note]]it's implied Bond's womanizing is a mask to hide the grief of losing the only woman he truly loved, Tracy di Vincenzo, to Ernst Blofeld in ''On Her Majesty's Secret Service[[/note]], and clinging on to outdated ideals.

** ''Film/{{Spectre}}'': Using PsychologicalProjection, Franz Oberhauser/[[spoiler:Ernst Stavro Blofeld]] claims that he and [[spoiler:C]] are "visionaries", alongside giving a NotSoDifferentRemark / HannibalLecture to 007. But Bond, aware that he and [[spoiler:C]] are nothing more than insane loons, [[ShutUpHannibal retorts that both of them are deranged]], in an homage to Bond's quote to Film/DrNo regarding world domination. "Psychiatric wards are full of them."

** After learning Thor's plan at the end of ''Film/ThorRagnarok'', Loki mutters to himself "This is madness".
** In ''Film/IronMan3'', Tony Stark says a varient of this to [[spoiler:[[TheManBehindTheMan Aldrich Killian]]]] after [[spoiler:he murders Maya Hansen just to put more misery on him]].

** ''Film/Godzilla2014'': A variation. When the military officers are [[IdiotBall seriously considering]] trying to kill Godzilla and the [=MUTOs=] by ''[[NukeEm dropping a nuke]]'' ([[NukeEm which Godzilla survived decades ago with no lasting damage and which will produce radioactive fallout that the kaiju can ''feast'' on]]), a horrified [[Characters/MonsterVerseMonarch Dr. Graham]] says, "This is crazy!"
** ''Film/GodzillaKingOfTheMonsters2019'': After hearing the extensive MotiveRant of [[spoiler:Emma Russell, his own ex-wife]], revealing she was in cahoots with [[EcoTerrorist Alan Jonah]] and that they intend to set all the Titans loose indiscriminately to bring GaiasVengeance and UtopiaJustifiesTheMeans, an outraged [[Characters/MonsterVerseMarkRussell Mark Russell]] tells her she's insane, then he directly calls her out for both [[spoiler:putting their daughter in danger]] and thinking she has the right to decide by herself the fate of the world.

** One time was when he attempts to escape from Lord Beckett's ship in ''Film/PiratesOfTheCaribbeanAtWorldsEnd'' by [[spoiler:blasting its mast down with a cannon and riding its rigging]] back to the ''Black Pearl''. When Beckett sees this, he tells Jack ''"You're mad."'' To which Jack replies "Thank goodness for that, because if I wasn't, this would probably never work."[[note]]In classic Sparrow fashion, it ''does'' work... and as revealed moments later, it worked without a drop of rum in his system.[[/note]]

* ''Film/SherlockHolmes2009'' pulls a somewhat more subtle version when Sherlock Holmes meets the SerialKiller BigBad Lord Blackwood.

* ''Film/TheWickerMan1973'':

* Spoken by the FinalGirl to the family in ''Film/TheTexasChainsawMassacre1974''.

--->'''Daylen:''' "Trust me, if I do, [[DrivenToSuicide I'll kill myself]]."\\
'''Ahrek:''' "No, Daylen, if you truly become anything like your father, ''I'' will kill you."\\
({{beat}})\\
'''Daylen:''' "[[SincerityMode Thank you. You're a better friend than I thought.]]"\\
'''Ahrek:''' "You're more than welcome."\\
'''Sain:''' "You two are completely insane!"

* In the original novel of ''Film/TheLastKingOfScotland'', a British tabloid newspaper interviews a psychiatrist on [[TheCaligula Idi Amin's bizarre behaviour]] and their conclusion is spelt out in the headline: HE'S MAD--IT'S OFFICIAL.
* ''The Devils Of D-Day'' by Creator/GrahamMasterton. The protagonist responds this way when offered a DealWithTheDevil. The demon making the offer just laughs. “Insanity is a human word which almost always describes the activities of devils."

--> '''Dick''': YOU'RE INSANE! And not Gallagher insane, just INSANE!

--->'''Oliver:''' Reiter, you're insane!
--->'''Baron Reiter:''' The difference between insanity and belief lies only in the number of believers.

--->'''Morden''': You're insane.\\
'''Londo''': Any other day, Mr. Morden, you would be wrong. Today is a very different day.

--->'''Buffy:''' [[DatingCatwoman I was insane to ever think]] you could just hang out with my friends.
--->'''Spike:''' And ''I'' was insane to think... No, wait. You were right. ''You're'' insane.

** "[[Recap/DoctorWhoS9E4TheMutants The Mutants]]": The Doctor gives this trope to the Marshal of Solos, who retorts, [[WrittenByTheWinners "Only if I lose."]]

* ''Series/TheFlash1990''. What Barry Allen says to Nicolas Pike after he's seen what his nemesis has done to Central City during his ten-year absence through accidental time travel.
* ''Series/GetSmart''. In "Shock It To Me", Smart and Agent 99 are captives of MadScientist Dr. Zharko:

--->'''Graham:''' Now you might say I'm a loony...
--->'''Bill and Tim:''' [[RhetoricalQuestionBlunder You're a loony!]]

* ''Series/StarTrekTheOriginalSeries'': A variant is used in the episode "[[Recap/StarTrekS1E7WhatAreLittleGirlsMadeOf What Are Little Girls Made of?]]", where a scientist tries to convince Capt. Kirk to participate in a twisted scheme to take over a planet of the Federation.
-->'''Kirk''': You've convinced me; you've convinced me that you're dangerous!
* ''Series/StarTrekDeepSpaceNine'':
** Spoken by Kira in the episode "[[Recap/StarTrekDeepSpaceNineS01E19Duet Duet]]" when a Cardassian war criminal starts gleefully boasting about his horrific crimes. [[spoiler:Only he's invoked the trope; he's intentionally behaving over-the-top in the hopes of forcing the Cardassian atrocities into the open. He isn't even the actual criminal; he's a file clerk who is impersonating the real criminal, with the intent of being ''executed'' for the man's crimes, because of his own traumatic memories of witnessing what happened and his guilt at being unable to stop it.]]
** PlayedForLaughs in "[[Recap/StarTrekDeepSpaceNineS05E19TiesOfBloodAndWater Ties of Blood and Water]]" when Weyoun 5 drinks a shot of poisoned kanar just to demonstrate how Vorta can't be killed with poison.
--->'''Weyoun:''' ''[shudders]'' Oh my. That is ''quite'' toxic, isn't it?\\

** And in [[Recap/StarTrekDeepSpaceNineS06E26TearsOfTheProphets "Tears of the Prophets"]], Weyoun gives the trope to Dukat.
--->'''Weyoun:''' You're right, Dukat, you have changed. You've gone from being a self-important egoist to a self-deluded madman. [[SarcasmMode I hardly call that an improvement.]]
* ''Series/StarTrekVoyager'': Said verbatim by Harry Kim in "[[Recap/StarTrekVoyagerS3E3TheChute The Chute]]" when he and Tom Paris are in a HellholePrison where all prisoners are implanted with a synaptic stimulator that increasingly impairs their mental function. Kim befriends an inmate who appears to be the OnlySaneMan among the prison population, but it's not long before the man's true colors start showing: while he's not violent the way the other prisoners are, he's a whole other kind of crazy.
-->'''Inmate:''' You've got a chance to make something of your life in here, but as long as that carcass [a badly injured Tom Paris] is in my hut, we'll never be able to go on to more important things.\\

* ''Series/StarTrekDiscovery'': Used in the episode "[[Recap/StarTrekDiscoveryS1E07MagicToMakeTheSanestManGoMad Magic to Make the Sanest Man Go Mad]]".
-->'''Michael Burnham:''' You are mad!\\

* ''Series/StarTrekPicard'':
** In "[[Recap/StarTrekPicardS1E02MapsAndLegends Maps and Legends]]", when Laris learns of Picard's plans to get BackInTheSaddle, she wonders if he has dementia.
--->'''Laris:''' What?! Have you gone mad? Is it dementia?\\

** In "[[Recap/StarTrekPicardS1E04AbsoluteCandor Absolute Candor]]", Raffi questions Picard's sanity after she finds out that he ordered Rios to change course for Vashti.
--->'''Raffi:''' You wanna go to Vashti?! Are you out of your goddamn mind?! [...] That you even suggest it makes me seriously question your mental state.
** In "[[Recap/StarTrekPicardS1E07Nepenthe Nepenthe]]", it's lampshaded by Rios, who believes Elnor is out of his mind for staying on the Artifact, which is crawling with Tal Shiar (the ArchEnemy of the Qowat Milat), instead of transporting back to ''La Sirena''.
--->'''Rios:''' Everyone here thinks you're ''crazy''.

* In ''Series/{{John Adams}}'', Alexander Hamiltons suggests to Adams, at the time President of the United States, in the name of "universal empire", to invade Central America in case of France winning the Napoleonic War. Adams reaction is less than enthusiastic.
-->'''Adams''' May I inform you as well, Sir, that I am in possession of intelligence which confirms that we are as likely to find a French army on these shores, as we are on the moon! You dream of "empire", Mr. Hamilton? \\
'''Hamilton''' You question my loyalty, Sir? \\
'''Adams''' Oh no, Mr. Hamilton, I question your ''sanity''! Now either you are stark raving mad, ''OR I AM''! Good day, Sir!

-->'''Trevor:''' No, this is insane...You're insane.

'''Andre:''' Pick on someb- THIS IS INSANE! I'm just farming, trying to grow enough food for my family... then you tiny people show up, start infesting my yard, beat up my cat and then you '''POISON MY SON!!!'''\\

-->'''Mom:''' You need to repent. You need to confess your sins, and become saved! Let His light inside you! CLEANSE YOUR SOUL!
-->'''Dad:''' You. Are. Insane. You are taking this too far! Can't you hear how you sound?
-->'''Mom:''' Pray with me! Pray for your salvation! Come, pray with us, Isaac...

* There was this exchange in ''Webcomic/PepsiaPhobia'', during the "Lord Night-Sorrow" story arc... before it was changed by a {{Retcon}}:

* Lieutenant Piebald (of ''Webcomic/SchlockMercenary'') is a MadBomber Demolitions Expert that is self-aware enough to pull this [[https://www.schlockmercenary.com/2012-02-26 on himself]]:
-->'''TAGON:''' Give me your favorite scenario for taking this base intact.\\
'''PI:''' "Favorite," or "most likely? See, I'm a little crazy, and my favorite scenario is '''''really''''' expensive.\\
'''TAGON:''' The Doctor briefs me weekly regarding exactly how crazy you are.

-->'''PI:''' With an enemy budget that big, sir, I'd have to be crazy to work on your side.\\
'''TAGON:''' Then it's a good thing you're not on your meds this week, Lieutenant.

* ''WebVideo/TheSpoonyExperiment'': "What is it about the name ''[[MadScientist Dr. Insano]]'' that eludes you people?!"

* This was the reaction the rest of the Creator/AchievementHunter team had in ''[[LetsPlay/AchievementHunterMinecraftSeries Let's Play Minecraft]]'' when they found out not only did Ryan had a cow in a hole in his home in Achievement City, he went out of his way to get another one to foil Michael's rescue attempt with the declaration of "Edgar's the one in the hole." His reigns as "King" have turned into "Mad King" and this was even shown in ''WebAnimation/XRayAndVav'' with his character the Mad King.

* ''WesternAnimation/DuckTales1987'':

* ''Literature/VillainessLevel99IMayBeTheHiddenBossButImNotTheDemonLord'': Pretty much everyone's reaction when Yumiella tells them what she did to get her level so high. This includes hunting monsters in the forest as a preteen, going alone into dungeons meant for parties, wearing magic equipment that boosts experience gains rather than offering any protection, and using a monster-summoning flute over and over to kill the summoned monsters for experience. She, not understanding the norms of society, doesn't realize why they are shocked.

** Towards the end of his solo run, after becoming somewhat... ''strange'' and taking up the mantle of a mutant 'Shaman', [[Characters/MarvelComicsXMan Nate Grey]] gets this, word for word. His entirely unfazed response? "Probably."

* ''Franchise/{{Transformers}}:
** WesternAnimation/BeastWars'' has [[MadScientist Tarantulas]] happily shrug this one off with a casual "So they say," and a particularly indulgent and spittle-y EvilLaugh.

* ''Franchise/{{Transformers}}: WesternAnimation/BeastWars'' has [[MadScientist Tarantulas]] happily shrug this one off with a casual "So they say," and a particularly indulgent and spittle-y EvilLaugh.

** WebVideo/TheNostalgiaCritic was on the other end of this during his review of ''Film/TheRoom''. Other reviewers kept showing up to try and talk him out of it: when he refused to listen to [[WebVideo/AtopTheFourthWall Linkara]]...

** EvilutionaryBiologist Nathaniel Essex's [[TheSocialDarwinist Social Darwinist]] rhetoric elicits a "Good heavens! You're... you're quite mad!" from UsefulNotes/CharlesDarwin himself.

** [[LoudOfWar Shriek]] is blackmailing Commissioner Gordon in exchange for Batman's life.

** When Xander outlines his plan to wipe out the world through triggered volcanic eruptions, while his followers will survive by turning themselves into dinosaurs and thriving off the excess heat.

-->'''El Seed:''' You are the glorious army of El Seed! I am on a big power trip, and you are coming with me!!! My assistants, the lovely Bee Twins, will hand out medical waiver forms and ball-point pens. [[LargeHam PLEASE... PRIIIINT... CLEEEEEARRRRLYYYYYYYY!!!]]\\

* In the ''WesternAnimation/{{Gargoyles}}'' episode "Temptation", Brooklyn, disillusioned by the problems of humanity, is manipulated by Demona to steal a spellbook in order to help his leader, Goliath, "see the truth of the world". Brooklyn cooperates, but when Demona attacks Goliath with a spell from the book that makes him a mind-controlled slave, the young gargoyle protests that he only wanted to Goliath to see the truth. Demona intones with flashing eyes, "You wanted him to know the truth. Now, our truth will the only truth he ever knows!" At that brazenly evil pronouncement, Brooklyn yells to Demona, "You're insane!" and attacks her to get the book back.

** In "Come the Apocalypse", Rogue recalls Xavier's earlier words and calls Apocalypse insane for turning mutants into mindless slaves and using them to destroy the world.

* In the ''WesternAnimation/SupermanTheAnimatedSeries'' episode "Stolen Memories", Superman meets Brainiac, the surviving major computer consciousness from Krypton. Although Superman is pleased to meet someone from his native planet, he later learns of Brainiac's true reason for coming to Earth. The intelligence has been ravaging the cosmos, gathering all the knowledge of worlds and then destroying them so he is the sole possessor of that information, and now wants to do the same with Earth. At this smug justification of serial omnicide, Superman yells, "You're insane!" and leaps into battle.
* A cousin to InsultBackfire happens in an episode of ''WesternAnimation/JusticeLeague'' where Superman is sent far into the future, AfterTheEnd:
-->'''Vandal Savage:''' The earth belongs to the cockroaches now... Oh, and me.\\

'''Vandal Savage:''' ... [[TheMadHatter True]]. But that doesn't mean I'm not good company. Say, you wanna come over to my house?\\
'''Superman:''' ...\\
'''Vandal Savage:''' Like you've got something ''better'' to do.
** Another one, in an episode of ''Justice League''
--->'''Solomon Grundy:''' ''[to Luthor]'' You're crazy!\\
'''The Joker:''' ''[[[WalkInChimeIn bursts into the room]]]'' And what's wrong with that? It's done ''wonders'' for me!

** "[[Recap/TheSimpsonsS8E2YouOnlyMoveTwice You Only Move Twice]]" spoofed this with their famous line (in thick Scottish accent): "Scorpio, you're mad!" And the equally memorable reply: "Hah, I wouldn't point fingers, you jerk!"
** {{Parodied|Trope}} in another episode, when Sideshow Bob is released from prison for the umpteenth time. Bart protests, calling Bob a maniac, and Mayor Quimby, who authorized Bob's release, replies, "Bob is no maniac. He explained his reasons for trying to kill us all, and I assure you they were perfectly sane."

** In "[[Recap/TheSimpsonsS8E1TreehouseOfHorrorVII Treehouse of Horror VII]]", Bart tells his [[ConjoinedTwins conjoined twin]] Hugo, "You're crazy!", to which Hugo replies, "Am I? Well, perhaps we're all a little crazy. I know I am."

** In the episode "Sozin's Comet, Part 1", when Team Avatar learns about [[BigBad Fire Lord Ozai's]] plans to use Sozin's comet to [[FinalSolution launch genocidal campaigns against the entire Earth Kingdom]], which will result in the deaths of countless innocents, they can only react with horror and shock. Sokka even lampshades on this.
--->'''Sokka:''' I always knew the Fire Lord was a bad guy, but his plan is just pure evil.
** A non-villainous example occurs in season one when an old herbalist hermit with only her ancient cat as a friend tells Aang to make his friends suck on frozen frogs to cure their illness.

** Occurs in the fourth season of ''WesternAnimation/TheLegendOfKorra'', when Varrick turns out to have [[spoiler:built a bomb ([[CrazyPrepared with both a timer and a manual switch]]) to destroy himself, Bolin and the spirit vine samples rather than let Kuvira and Baatar Jr. get their hands on [[GoneHorriblyRight the accidental fruits of his research]]. Thanks to some quick thinking from Bolin, they escape.]]
--->'''Baatar Jr.:''' You're insane!\\

** The Joker gets this quite a lot, as while people already know he's loony, he can still boggle their minds;
*** In "Joker's Favor", Charlie Collins has lived in terror over what 'favor' Joker will have him, to the point of changing his name and moving across the country (To no avail), so he's a little thunderstruck that all Joker wants from him is to open a door and let Harley Quinn push a cake to Commissioner Gordon's dinner.
-->'''Charlie:''' Wait, that's the favor? You called me out here just to open a door?\\

'''Charlie:''' ''(Aside)'' He's nuts...

* From the Ruby-Spears ''WesternAnimation/{{Mega Man|RubySpears}}'' cartoon, in the episode "Ice Age" (sound clip available about a third of the way down [[http://www.mmhp.net/Marketing/ShowList.html this page]]):

* ''Series/{{MASH}}''. In "The Light That Failed", the characters argue over who committed the murder in a mystery novel with the last page missing. They're no wiser by the end of the episode, so Hawkeye confesses to the murders. When BJ responds with this trope, he pretends to go LaughingMad and hauls off a willing nurse to have his wicked way with her.

* On ''Series/{{Yellowjackets}}'', Misty Quigley's biggest secret is that she [[BurningTheShips sabotaged]] the emergency transmitter that might have allowed the Yellowjackets to be rescued from being stranded in the wilderness. Throuhgout the second season, Misty develops a friendship with a fellow survivor named Crystal. She eventually decides to reveal to her that she sabotaged the transmitter. Instead of whatever reaction she expected, Crystal tells her "You're a psycho."

* There was this exchange in ''Webcomic/GastroPhobia'', during the "Lord Night-Sorrow" story arc... before it was changed by a {{Retcon}}:

* ''Fanfic/AbraxasHrodvitnon'': In Chapter 8 of this ''Film/GodzillaKingOfTheMonsters2019'' fanfiction, [[Characters/AbraxasHrodvitnonHumans Mark Russell]], who is currently in the midst of one of his infamous tempers at hearing the news (which he's convinced is a lie) that Vivienne Graham is BackFromTheDead, says this ad verbatim to Mariko (who originally broke the news) in response to Mariko calling Mark out on his ArbitrarySkepticism of the idea that Vivienne's resurrection is even possible.

** ''Film/GodzillaKingOfTheMonsters2019'': After hearing the extensive MotiveRant of [[spoiler:Emma Russell, his own ex-wife]], revealing she was in cahoots with [[EcoTerrorist Alan Jonah]] and that they intend to set all the Titans loose indiscriminately to bring GaiasVengeance and UtopiaJustifiesTheMeans, an outraged [[Characters/MonsterVerseFamilies Mark Russell]] tells her this, then directly calls her out for both [[spoiler:putting their daughter in danger]] and thinking she has the right to decide by herself the fate of the world.

* ''Film/{{The WickerMan|1973}}'':

* ''Series/{{Arrow}}''

* ''Series/BlakesSeven''. In "Rescue", VillainOfTheWeek Dorian tells Avon he has a room that gives him youth and immortality (it's ''Literature/ThePictureOfDorianGray'' InSpace). When Avon responds with this trope, Dorian admits that if it weren't for his Room purging all negativity, he probably would be.

* ''Series/StarTrekVoyager'': Said verbatim by Harry Kim when he and Tom Paris are in a HellholePrison where all prisoners are implanted with a synaptic stimulator that increasingly impairs their mental function. Kim befriends an inmate who appears to be the OnlySaneMan among the prison population, but it's not long before the man's true colors start showing: while he's not violent the way the other prisoners are, he's a whole other kind of crazy.

* ''Series/StarTrekDiscovery'': Used in the episode "Magic to Make the Sanest Man Go Mad".

** In "Maps and Legends", when Laris learns of Picard's plans to get BackInTheSaddle, she wonders if he has dementia.
--->'''Laris''': What?! Have you gone mad? Is it dementia?\\
'''Picard''': I beg your pardon?\\
'''Laris''': Sorry, but you're not a stupid man, so when I hear you say such a stupid idea, I have to ask for other explanations.

--->'''Raffi''': You wanna go to Vashti?! Are you out of your goddamn mind?! [...] That you even suggest it makes me seriously question your mental state.
** In "Nepenthe", it's lampshaded by Rios, who believes Elnor is out of his mind for staying on the Artifact, which is crawling with Tal Shiar (the ArchEnemy of the Qowat Milat), instead of transporting back to ''La Sirena''.
--->'''Rios''': Everyone here thinks you're ''crazy''.