History Main / ModifiedClone

->'''Mewtwo''': Am I only a copy? Nothing but Mew's shadow?
->'''Dr. Fuji''': You are greater than Mew, improved through the power of human ingenuity.

* Most clones in ''Franchise/LyricalNanoha'' are modified in some manner, even before ClonesArePeopleToo is factored in. Almost all of them are more powerful mages than their originals and the combat cyborgs in particular have been adjusted to keep their bodies from rejecting all their mechanical implants.

* ''Manga/TwinSpica'' has [[spoiler:Marika]]--who isn't so much modified as was born and raised almost a generation after her original, after the invention of a treatment for the fatal hereditary condition she and her original share. Later on in the series, she takes care of a tree which plays this trope straight--a genetically modified tree which is tougher against cold and higher elevation, and could be suitable for early biospheres on Mars.
* ''Manga/WorldsEndHarem'': [[spoiler:This is revealed to be the reason for the resemblance between Mira Suou and Elisa Tachibana, as Mira was directly cloned from Elisa, but modified to be physically more endowed and with a mole on her face]].

* Several authors of ''Franchise/WonderWoman'' present the titular character as essentially a magically created clone of her mother Hippolyta with added boons of power from Aphrodite, and/or the other goddesses with have been associated with her creation over the various reboots.
* ''ComicBook/XMen'': The Stepford Cuckoos (or the Five-in-One, or Weapon XV) are five genetically modified clones of Emma Frost. They're TheAgeless and are telepathically linked. Oh, and they're a living superweapon designed to help wipe out Mutantkind. (There were thousands more of their 'sisters', but they got incinerated.)

** A recurring subplot of ''Comicbook/AllNewWolverine'' and ''X-23 Vol. 4'' is Dr. Chandler's attempts to duplicate X-23, first with the Sisters, and later with the X-Assassins:

*** The X-Assassins were modified by completely eliminating their HealingFactor altogether, attempting to bypass Laura's pesky morality by making them disposable cyborgs. Further experiments building off the same project led to Laura's DNA being used to create genetically modified...[[spoiler:''turkeys'']].
* ''ComicBook/JudgeDredd'' had a clone named Nimrod who was modified to have SuperSenses. Unfortunately, the modifications also caused CloneDegeneration, debilitating Nimrod to the point where he had frequent seizures. Due to his injuries and his condition, Dredd is forced to MercyKill him after he saves Vienna from a would be rapist.

* ''Franchise/{{Godzilla}}''

* ''Franchise/StarWars'': ''Film/AttackOfTheClones'': The CloneArmy are modified to age at twice the normal rate, and follow orders practically without question. Their genetic template, Jango Fett, commissioned an unmodified clone to raise as a son, Boba.

* In the sequel to ''VideoGame/DestroyAllHumans'', after Natalya is killed, Crypto uses the cloning machine to bring her back. However, he makes a few adjustments, which are for her to be head over heels in love with him.
* The main plot of VideoGame/{{MUGEN}}'s fullgame ''VideoGame/AntiGoukiProject'' is about clones of [[VideoGame/StreetFighterII Akuma]] made with this fighter's DNA but implanted with different personalities and powers, being the game a TournamentArc that decides which clone will lead the CloneArmy to TakeOverTheWorld.
* ''Franchise/{{Pokemon}}''. Mewtwo is a genetically modified clone of [[OlympusMons the mythical Mew]], looking more humanoid and being larger and stronger than it. At its introduction it was the strongest Pokemon of the game, and thanks to [[SuperMode Mega Evolution]] contests that position with Mega Rayquaza. [[GoneHorriblyRight Unfortunately for its creators, Mewtwo proved too strong]]. In ''Manga/PokemonAdventures'', the Mew DNA sample was incomplete so the scientists spliced it with human DNA; in ''Anime/PokemonTheFirstMovie'' (at least its Western dubs) they simply chose to make him stronger.
* ''VideoGame/SaintsRowTheThird'': The Syndicate's muscle mooks, the "Brutes", are heavily dumbed-down and hyper-weaponized clones of ex-KGB agent Oleg Kirrlov. His contribution to their development wasn't exactly voluntary, and after being liberated he helps the Saints bring down the Syndicate.
* ''VideoGame/UtawarerumonoMaskOfTruth'': [[spoiler:Anju, the Imperial Princess]], turns out to be a heavily altered clone of Chii, a human girl who lived before [[spoiler:humanity was wiped out]]. While we don't see what Chii actually looked like, it's a pretty good bet she didn't have the animal ears and tail common to the people in ''Utawarerumono'', not to mention SuperStrength, super stamina, or poison resistance.

* ''Webcomic/ElGoonishShive:'' When used to remove curses from someone, the Dewitchery Diamond creates a duplicate of that person's cursed form, which has all the original's memories up to the moment of divergence, but its own mind and soul thereafter.
* In ''Webcomic/GenocideMan'' Fumiaki made some "improvements" to his clone-son Kenshiro's genome, better looks, no astigmatism, [[spoiler:replacing his brain with an AI core.]]

* ''WesternAnimation/StarWarsTheBadBatch'': The titular characters are a squad of clone troopers who were made with mutations or enhancements that make them superior to ordinary clones and result in each them having different appearances and builds. Most notably [[spoiler:the biochips that compel "regs" to follow Order 66 don't work on them.]] SixthRanger and LivingMacguffin Omega, a product of the same experiment, is a plain OppositeSexClone of the original Jango with no other apparent modifications, even the RapidAging all clones share. [[spoiler:Then subverted when it turns out she ''isn't'' a product of the same experiment; she's a pure clone of Jango Fett like Boba is, which raises a lot of questions.]]

SuperTrope of OppositeSexClone.

* ''Literature/ACertainMagicalIndex'': The MISAKA series are a CloneArmy based on the teenage Misaka "Railgun" Mikoto, one of the world's strongest espers; while their [[ShockAndAwe electric powers]] are far inferior to the original's, they receive "programming" at birth which allows them to link their brainwaves into a HiveMind ([[spoiler:which was in fact the true reason for the project, as there are a ''lot'' of ways to abuse such a large mass of psychic energy]]). Much later, the series introduces [=MISAKA Worst=], a clone that's been aged to around sixteen and modified into a SuperSoldier; Worst's powers are much closer to the original's, though she mostly uses them to [[HavingABlast create explosions]].

* ''Literature/VorkosiganSaga'': This is [[InvertedTrope Inverted]] with Miles's clone-brother Mark. As Mark was growing up, he was altered to match Miles's appearance, because otherwise he would have come out looking rather like their cousin Ivan.

* ''TabletopGame/{{Battletech}}'': The Clans don't go in for literal cloning, or even much direct genetic manipulation beyond mundane selective breeding, but the DesignerBabies they raise with their [[UterineReplicator "iron womb"]] technology have a couple of very distinct Warrior sub-castes optimised for a particular task. Elementals are larger and stronger than average in order to make better infantry[[note]]Which ended up being a bit pointless, as by the time the first generation reached maturity they were in the process of rolling out [[PoweredArmour battlearmour]], but for whatever reason they carried on with the project[[/note]], whereas the aerospace pilot phenotype are the exact opposite (and would probably look "chibi" in an extremely un-kawaii way in real life), being smaller and lighter with disproportionately large eyes. The practical value of these programs ultimately proved to be rather limited.