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* In ''Film/HitmansWifesBodyguard'', Sonya gives Bryce some pills to help his broken ribs. The pills turn out to be lithium, causing Bryce to fall asleep during in the back of a van during a lengthy car chase.
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* In Creator/CharlieChaplin's short film ''Film/TheCure'', the protagonist has gone to a health spring resort to cure himself of alcoholism. The management finds his secret stash of alcohol and gets rid of it . . . by throwing it out the window, and right into the health spring. A wild party ensues.

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* In Creator/CharlieChaplin's short film ''Film/TheCure'', ''Film/TheCure1917'', the protagonist has gone to a health spring resort to cure himself of alcoholism. The management finds his secret stash of alcohol and gets rid of it . . . by throwing it out the window, and right into the health spring. A wild party ensues.
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* In the WebVideo/YuGiOhTheAbridgedSeries fanfic ''FanFic/DecksFallEveryoneDies'', Tristan gets drunk on "[[ParodyName Abysmalinth]]," not realizing how strong it is until he starts hallucinating.
* In ''FanFic/DiariesOfAMadman'', Nav and Pinkie spice up the Gala by placing out food laced with various drugs.

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* In the WebVideo/YuGiOhTheAbridgedSeries fanfic ''FanFic/DecksFallEveryoneDies'', ''Fanfic/DecksFallEveryoneDies'', Tristan gets drunk on "[[ParodyName Abysmalinth]]," not realizing how strong it is until he starts hallucinating.
* In ''FanFic/DiariesOfAMadman'', ''Fanfic/DiariesOfAMadman'', Nav and Pinkie spice up the Gala by placing out food laced with various drugs.



* In ''[[VideoGame/HarvestMoonAnimalParade Harvest Moon: Animal Parade]]'' fanfic ''[[https://www.fanfiction.net/s/11308945/20/Stumbling-Out-of-the-Shadows Stumbling Out of the Shadows]]'', protagonist [[ShrinkingViolet Kasey]] winds up in the clinic ([[RunningGag for the third time in the story]]) after being frozen from the inside out and nearly dying in the process. He's put on painkillers and ends up rambling at length about craving hamburgers and what his hypothetical cows would think about that, asking if [[spoiler: he's a zombie now since he briefly died from his injuries]], nonchalantly [[StraightGay outing himself]] to half the room (compared to having an [[{{Gayngst}} anxiety attack]] a few chapters earlier when Anissa figured it out on her own), [[OfficialCouple hitting on Toby]] (...sort of), revealing that he knows more than he let on about why Castanet is dying, and accusing Jin of stabbing off his arm because there's an IV drip running into it. Even [[ProperLady Anissa]], [[TheStoic Jin]], and [[TheQuietOne Toby]] have trouble keeping straight faces while he's going off on his tangents.
* In the ''Manga/DeathNote'' fic ''FanFic/TiredAndEmotional'' L apparently gets very, ''very'' drunk off a few drops of brandy.
* This trope sums up ''[[FanFic/TheVinylAndOctaviaSeries Vinyl and Octavia Get Incredibly Drunk]]'' quite nicely.

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* In ''[[VideoGame/HarvestMoonAnimalParade Harvest Moon: Animal Parade]]'' ''VideoGame/HarvestMoonAnimalParade'' fanfic ''[[https://www.fanfiction.net/s/11308945/20/Stumbling-Out-of-the-Shadows Stumbling Out of the Shadows]]'', protagonist [[ShrinkingViolet Kasey]] winds up in the clinic ([[RunningGag for the third time in the story]]) after being frozen from the inside out and nearly dying in the process. He's put on painkillers and ends up rambling at length about craving hamburgers and what his hypothetical cows would think about that, asking if [[spoiler: he's a zombie now since he briefly died from his injuries]], nonchalantly [[StraightGay outing himself]] to half the room (compared to having an [[{{Gayngst}} anxiety attack]] a few chapters earlier when Anissa figured it out on her own), [[OfficialCouple hitting on Toby]] (...sort of), revealing that he knows more than he let on about why Castanet is dying, and accusing Jin of stabbing off his arm because there's an IV drip running into it. Even [[ProperLady Anissa]], [[TheStoic Jin]], and [[TheQuietOne Toby]] have trouble keeping straight faces while he's going off on his tangents.
* In the ''Manga/DeathNote'' fic ''FanFic/TiredAndEmotional'' ''Fanfic/TiredAndEmotional'' L apparently gets very, ''very'' drunk off a few drops of brandy.
* This trope sums up ''[[FanFic/TheVinylAndOctaviaSeries ''[[Fanfic/TheVinylAndOctaviaSeries Vinyl and Octavia Get Incredibly Drunk]]'' quite nicely.



* LiveActionTV/ComedyCentralRoastOfPamelaAnderson: Several of the roasters got noticeably drunk and drunker over the course of the show. This goes double for Courtney Love, who started off trashed and got worse from there.

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* LiveActionTV/ComedyCentralRoastOfPamelaAnderson: ''Series/ComedyCentralRoastOfPamelaAnderson'': Several of the roasters got noticeably drunk and drunker over the course of the show. This goes double for Courtney Love, who started off trashed and got worse from there.
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* On ''Series/MikeAndMolly'', Mike accidentally ingests marijuana from gelato made by Victoria's pot dealer. He then wanders the streets of Chicago in a series of scenes spoofing ''Film/{{Frankenstein 1931}}''.

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* On ''Series/MikeAndMolly'', Mike accidentally ingests marijuana from gelato made by Victoria's pot dealer. He then wanders the streets of Chicago in a series of scenes spoofing ''Film/{{Frankenstein 1931}}''.''Film/Frankenstein1931''.



* In ''VideoGame/{{Guild Wars 2}}'', if the player joins the Order of Whispers, the order agent, Tybalt, decides to distract a group of pirates by challenging them to a drinking contest on the player character's behalf. Your character consequently sounds very tipsy during the next few cutscenes.

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* In ''VideoGame/{{Guild Wars 2}}'', ''VideoGame/GuildWars2'', if the player joins the Order of Whispers, the order agent, Tybalt, decides to distract a group of pirates by challenging them to a drinking contest on the player character's behalf. Your character consequently sounds very tipsy during the next few cutscenes.



* In ''VideoGame/{{Metro 2033}}'', there is a room with bad air. It's so bad that it seeps through your gas mask and gets you and Burbon high. Bourbon starts babbling on about a "Great Gate" and "marvellous songs". You get a "Hallucination" play-type, no shooting and lurching movements.

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* In ''VideoGame/{{Metro 2033}}'', ''VideoGame/Metro2033'', there is a room with bad air. It's so bad that it seeps through your gas mask and gets you and Burbon high. Bourbon starts babbling on about a "Great Gate" and "marvellous songs". You get a "Hallucination" play-type, no shooting and lurching movements.



* ''VideoGame/{{Persona 4}}'', during the school field trip, the Investigation team (particularly Rise, Yukiko, and Teddie) get a little tipsy when hanging out at a local night club. This leads to the downright hilarious "King's Game" incident. How they managed to get drunk from non-alcoholic beverages (since the club explicitly stopped selling alcohol several years prior due to a rash of drunk-driving incidents) is something we will never figure out[[note]]The other characters are pretty sure they're just playing it up, using the "alcohol" as a convenient excuse[[/note]].

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* ''VideoGame/{{Persona 4}}'', ''VideoGame/Persona4'', during the school field trip, the Investigation team (particularly Rise, Yukiko, and Teddie) get a little tipsy when hanging out at a local night club. This leads to the downright hilarious "King's Game" incident. How they managed to get drunk from non-alcoholic beverages (since the club explicitly stopped selling alcohol several years prior due to a rash of drunk-driving incidents) is something we will never figure out[[note]]The other characters are pretty sure they're just playing it up, using the "alcohol" as a convenient excuse[[/note]].



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** A rare [[DefiedTrope defiance]] of this Trope appears in the episode "Homer Goes To College" (as part of the running plot point that he [[WrongGenreSavvy doesn't understands]] a [[ThisIsReality "real" University]] is ''not'' a place for WackyFratboyHijinks a la ''Film/AnimalHouse''): Homer spikes the punch of the admittance party of Springfield University in order to "cause some ruckus" and two seconds after he slinks away a chaperone takes a sip of the punch, immediately notices that it's got alcohol, hurls what he's sipped into a handkerchief, and picks up a microphone to warn everybody else in the room to not drink it.

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** A rare [[DefiedTrope defiance]] of this Trope appears in the episode "Homer Goes To College" (as part of the running plot point that he [[WrongGenreSavvy doesn't understands]] understand]] a [[ThisIsReality "real" University]] is ''not'' a place for WackyFratboyHijinks a la ''Film/AnimalHouse''): Homer spikes the punch of the admittance party of Springfield University in order to "cause some ruckus" and two seconds after he slinks away a chaperone takes a sip of the punch, immediately notices that it's got alcohol, hurls what he's sipped into a handkerchief, and picks up a microphone to warn everybody else in the room to not drink it.



* ''WesternAnimation/TeenTitans'' features a much darker version of this trope when [[spoiler:Robin inhales a hallucinogen and believes the assumed-dead Slade to be plotting to destroy the city and attacking him - he's so convinced it's real that he actually reacts to the nonexistent blows and comes out of the ordeal bruised and battered, with [[ClothingDamage tattered clothes]], as if they had been real. FridgeHorror ensues...''he was doing this to himself.'']] Ironically lampshaded by Robin himself with the following line: "Do you think I'm doing this to myself?!"

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* ''WesternAnimation/TeenTitans'' ''WesternAnimation/TeenTitans2003'' features a much darker version of this trope when [[spoiler:Robin inhales a hallucinogen and believes the assumed-dead Slade to be plotting to destroy the city and attacking him - he's so convinced it's real that he actually reacts to the nonexistent blows and comes out of the ordeal bruised and battered, with [[ClothingDamage tattered clothes]], as if they had been real. FridgeHorror ensues...''he was doing this to himself.'']] Ironically lampshaded by Robin himself with the following line: "Do you think I'm doing this to myself?!"
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(''[[AnswerCut cut to Russell standing on the roof of the house'']])\\

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(''[[AnswerCut cut to Russell standing on the roof of the house'']])\\house]]'')\\

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* ''Film/AlmostFamous'': Russell and William go to a party, and Russell drinks from a cup of beer laced with acid, leading to this exchange:
-->'''William''': (''on the phone'') How do I know when the acid kicks in?\\
(''[[AnswerCut cut to Russell standing on the roof of the house'']])\\
'''Russell''': I AM A GOLDEN GOD!



* In the ''Series/BuffyTheVampireSlayer'' episode "[[Recap/BuffyTheVampireSlayerS2E3SchoolHard School Hard]]", recounts an incident where he "fed off a flower person" at Woodstock. ("...and I spent the next six hours [[ContemplatingYourHands watching my hand move]].") Vampires in the Buffyverse are especially susceptible to unwittingly taking drugs by drinking the blood of users, and one episode depicts a designer drug meant to be shared by a human and a vampire.

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* In the ''Series/BuffyTheVampireSlayer'' episode "[[Recap/BuffyTheVampireSlayerS2E3SchoolHard School Hard]]", Spike recounts an incident where he "fed off a flower person" at Woodstock. ("...and I spent the next six hours [[ContemplatingYourHands watching my hand move]].") Vampires in the Buffyverse are especially susceptible to unwittingly taking drugs by drinking the blood of users, and one episode depicts a designer drug meant to be shared by a human and a vampire.



* President Bartlet on ''Series/TheWestWing'' complains in a first-season episode that his back medication makes him loopy...and is proven right, as when on the painkillers (two different opiates) at the end of the episode, he spaces out, confuses the names of his staff, and announces -- with all the gravitas of the President of the United States -- that he's been seriously thinking about getting a dog.

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* President Bartlet on ''Series/TheWestWing'' complains in a the first-season episode "Five Votes Down" that his back medication makes him loopy...and is proven right, as when on the painkillers (two different opiates) at the end of the episode, he spaces out, confuses the names of his staff, and announces -- with all the gravitas of the President of the United States -- that he's been seriously thinking about getting a dog.
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* ''Series/DerryGirls'': Granda Joe eats one of [[HardDrinkingPartyGirl Michelle]]'s scones, not knowing they contained hash. Erin realizes that he's high because he's nice to her father for once.
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-->-- '''[[WebAnimation/HomestarRunner Strong Sad]]''', after drinking orange juice laced with several heaping spoonfuls of (decaffeinated) [[ICantBelieveItsNotHeroin instant coffee]], ''WebAnimation/StrongBadEmail'' #91 [[Recap/StrongBadEmailE88Caffeine "caffeine"]]

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-->-- '''[[WebAnimation/HomestarRunner Strong Sad]]''', after drinking orange juice laced with several heaping spoonfuls of (decaffeinated) [[ICantBelieveItsNotHeroin instant coffee]], ''WebAnimation/StrongBadEmail'' #91 [[Recap/StrongBadEmailE88Caffeine [[Recap/StrongBadEmailE91Caffeine "caffeine"]]
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-->-- '''Strong Sad''', after drinking orange juice laced with several heaping spoonfuls of (decaffeinated) [[ICantBelieveItsNotHeroin instant coffee]], ''WebAnimation/HomestarRunner''

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-->-- '''Strong Sad''', '''[[WebAnimation/HomestarRunner Strong Sad]]''', after drinking orange juice laced with several heaping spoonfuls of (decaffeinated) [[ICantBelieveItsNotHeroin instant coffee]], ''WebAnimation/HomestarRunner''
''WebAnimation/StrongBadEmail'' #91 [[Recap/StrongBadEmailE88Caffeine "caffeine"]]
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* In 2014, BBC Middle East correspondent Quentin Sommerville and his crew were reporting on the destruction of over eight tons of narcotics in [[UsefulNotes/TheWarOnTerror Afghanistan]], but stood a little too close to the flames. The result? [[https://www.youtube.com/watch?v=kLYVTdiACRA One very giggly correspondent.]]

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* In 2014, BBC Middle East correspondent Quentin Sommerville and his crew were reporting on the destruction burning of over eight and a half tons of heroin, opium, hash and other assorted narcotics in [[UsefulNotes/TheWarOnTerror Afghanistan]], but stood a little too close to the flames. The result? [[https://www.youtube.com/watch?v=kLYVTdiACRA One very giggly correspondent.]]
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*** In an even more questionable move, some parents advocate drugging their children with medicines such as Benadryl and Codeine (both known to cause somnolence at therapeutic doses), or even plying them with alcohol so they're completely paralytic; this, for many reasons, is a bad idea, not least because it's literally ''(over)dosing a child with medicines just so you don't have to parent them'', but also because a phenomenon called a [[https://en.wikipedia.org/wiki/Paradoxical_reaction paradoxical reaction]] to the meds may take place. In the case of medicines that normally cause drowsiness and somnolence, these parents can have fun trying to wrangle a miserable, overtired child who's disoriented, scared, and completely inconsolable.
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* The ''WesternAnimation/{{Amphibia}}'' episode "Adventures in Catsitting" ends with Anne returning home high on dental painkillers and extremely delirious as a result, blurting out an [[WordSaladPhilosophy incredibly nonsensical]] IceCreamKoan about Domino while squeezing Hop Pop's cheeks.

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* The ''WesternAnimation/{{Amphibia}}'' episode "Adventures in Catsitting" ends with Anne returning home high on dental painkillers and extremely delirious and incoherent as a result, blurting out an [[WordSaladPhilosophy incredibly nonsensical]] IceCreamKoan about Domino while squeezing Hop Pop's cheeks.
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* LiveActionTV/ComedyCentralRoastOfPamelaAnderson: Several of the roasters got noticeably drunk and druker over the course of the show. This goes double for Courtney Love, who started off trashed and got worse from there.

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* LiveActionTV/ComedyCentralRoastOfPamelaAnderson: Several of the roasters got noticeably drunk and druker drunker over the course of the show. This goes double for Courtney Love, who started off trashed and got worse from there.
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** There was also the time they all got sick for the first time, where Dick makes an ass out of himself at Mary's friend's wedding after chugging a whole bottle of cough syrup.
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* The ''WesternAnimation/WanderOverYonder'' episode "The Fremergency Fronfract" involves Wander and Sylvia hanging around with Lord Hater, who is extremely loopy from the painkillers given to him during his dentist appointment. Wander sees this as an opportunity to sway Hater from the side of evil and strike up a friendship with him. Sylvia is skeptical, but she goes along with Wander because she finds Hater's antics while high on anesthetics [[ItAmusedMe to be funny.]] In the end, Wander realizes that he shouldn't to try to be friends with Hater while he's high on the anesthetics because "true friendship comes from the heart, not an electric squid to the face."
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[[folder:Mythology and Religion]]
* In Myth/EgyptianMythology, Sekhmet went on [[OmnicidalManiac an omnicidal rampage]], trying to wipe out all of humanity. To stop her slaughter, Ra exploited her habit of drinking the blood of her victims and covered the location of her next rampage with alcohol made to look like blood (either red wine, or beer mixed with red dye). Once she got there, she figured that she must have already killed everyone there before and just forgot about it, so she skipped straight to the blood-drinking part. The result got her so drunk that in some versions of the myth, she underwent a HeelFaceTurn and became Hathor, goddess of love and, appropriately enough, drinking and partying.
[[/folder]]
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* The ''WesternAnimation/{{Amphibia}}'' episode "Adventures in Catsitting" ends with Anne returning home high on dental painkillers and extremely delirious as a result, blurting out an [[WordSaladPhilosophy incredibly nonsensical]] IceCreamKoan about Domino while squeezing Hop Pop's cheeks.
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* In ''Manga/CaseClosed'', Heiji gives Conan some Chinese wine as a medicine, and is scolded by Ran when he becomes totally wasted. Made funnier in the dub because Conan starts hitting on Ran.



* In ''Manga/DetectiveConan'', Heiji gives Conan some Chinese wine as a medicine, and is scolded by Ran when he becomes totally wasted. Made funnier in the dub because Conan starts hitting on Ran.

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* In ''Manga/DetectiveConan'', Heiji gives Conan some Chinese wine as a medicine, and is scolded by Ran when he becomes totally wasted. Made funnier in the dub because Conan starts hitting on Ran.
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** At some point in the series, Meatwad under questionable supervision from Carl, gets into the medicine cabinet. When Frylock and Shake find him, he's taken the shape of a potted flower saying "I am harmony, these is some good jellybeans. When he looks at Frylock, what he sees is... twisted to say the least.

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** At some point in the series, Meatwad under questionable supervision from Carl, gets into the medicine cabinet. When Frylock and Shake find him, he's taken the shape of a potted flower saying "I am harmony, these is some good jellybeans. When he looks at Frylock, what he sees is... twisted [[https://styles.redditmedia.com/t5_ds0z4/styles/profileIcon_d8e3d7gpeiq61.jpg twisted]] to say the least.
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* In an episode of ''Series/MysteryScienceTheater3000'', Crow creates a GargleBlaster called a "Killer Shrew" out of about a dozen different sugary substances. A single sip sends TV's Frank on a hyperglycemic bender as he races around the lab jabbering madly, then passes out.

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* In an episode of ''Series/MysteryScienceTheater3000'', Crow creates a GargleBlaster ScrewballSerum called a "Killer Shrew" out of about a dozen different sugary substances. A single sip sends TV's Frank on a hyperglycemic bender as he races around the lab jabbering madly, then passes out.
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->[excited] '''''I FEEL GREAT! I FEEL GREAT! I FEEL GREAT!''''' [suddenly depressed and dejected] ''I feel bad.'' [suddenly excited again] ''I don't even watch football! I don't even watch football! I can't remember my legs!''

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->[excited] '''''I "'''''I FEEL GREAT! I FEEL GREAT! I FEEL GREAT!''''' GREAT!'''''" [suddenly depressed and dejected] ''I "''I feel bad.'' ''" [suddenly excited again] ''I "''I don't even watch football! I don't even watch football! I can't remember my legs!''legs!''"
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* ''WesternAnimation/TotalDrama World Tour'': Gwen accidentally injects herself with Cody's [=EpiPen=] and goes erratic, with EyeTwitch and a MotorMouth. This proves counterproductive to the pickle she's in, rambling over a walkie-talkie about how [[ItMakesSenseInContext she's been captured with her hand in Cody's pants]].
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* In ''Webcomic/{{Narbonic}}'' storyline ''Professor Madblood and the Wetware Interface'', Madblood aquires Dave's brain (ItMakesSenseInContext) which he then uses as WetwareCPU in a robot he's built. Problem is, he puts the brain in an ''alcohol solution''. This would have killed it if laws of physics were obeyed, but since Madblood has TheSparkOfGenius, it merely makes Dave more drunk than he's ever been on page. And amorous towards Helen for the first time, even though he can't really do what he wants to do.
--> '''Helen''' (shocked): I don't think any human is equipped for ''that''.
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---> "Urg... I think there was something funny in that hippie. People of Earth - oh, that hippie's starting to kick in - we have all learned a important lesson today! I realize now that - dude! My hands are huge! They can touch anything but themselves. ''(touches them together)'' Oh, wait."

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---> "Urg...--->"Urg... I think there was something funny in that hippie. People of Earth - oh, that hippie's starting to kick in - we have all learned a important lesson today! I realize now that - dude! My hands are huge! They can touch anything but themselves. ''(touches them together)'' Oh, wait."



---> [[ContemplatingYourHands Clack... clack.]] And then minutes later: "Oh God, ''I'm coming down!!''"

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---> [[ContemplatingYourHands --->[[ContemplatingYourHands Clack... clack.]] And then minutes later: "Oh God, ''I'm coming down!!''"



* WesternAnimation/BugsBunny, typically [[OnlySaneMan one of the only sane characters]] in ''WesternAnimation/TheLooneyTunesShow'', gets high on energy drinks in one episode and goes completely off the rails.

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* WesternAnimation/BugsBunny, typically [[OnlySaneMan one of the only sane characters]] in ''WesternAnimation/TheLooneyTunesShow'', gets high hopped up on energy drinks in one episode and goes completely off the rails.
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* In ''[[https://www.fanfiction.net/s/13823122/1/Crushed-Spirit Crushed Spirit]]'', [[WesternAnimation/ThomasAndFriends Emily]] and [[OriginalCharacter David]] get drunk on [[ItMakesSenseInContext water that's had alcohol added to it]] (it was Diesel's fault).
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* LiveActionTV/ComedyCentralRoastOfPamelaAnderson: Several of the roasters got noticeably drunk and druker over the course of the show. This goes double for Courtney Love, who started off trashed and got worse from there.
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Disambiguating Series.Kingdom


* In a third-season episode of ''Series/{{Kingdom}}'', the title character, Peter Kingdom, eats an omelet containing some special mushrooms. It's doubly funny because it's Creator/StephenFry.

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* In a third-season episode of ''Series/{{Kingdom}}'', ''Series/Kingdom2007'', the title character, Peter Kingdom, eats an omelet containing some special mushrooms. It's doubly funny because it's Creator/StephenFry.
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* In ''WesternAnimation/TheLionKingIISimbasPride'', Vitani and Nuka travel to [[CallBack the elephant graveyard]] so they can use the geothermal vents to make fire. One of the vents erupts [[TooDumbToLive right as Nuka is looking into it]]. He's visibly high as a kite for several scenes afterwards, which also apparently awakened his {{Pyromaniac}} tendencies.
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* ''Series/CriminalMinds'' has perhaps the ''[[{{Deconstruction}} darkest]]'' take on this trope anywhere, when [[TheWoobie Reid]] is kidnapped by a man with three personalities: His abusive father, the angel Raphael, and the man himself, Tobias, who is meek and afraid of the others. After the first two torture Reid, Tobias gives him his own personal drug blend to help with the pain...and [[UnwittingInstigatorOfDoom ends up causing more trouble than the other two combined]], [[RealityEnsues since Reid becomes addicted. He has to struggle to get clean and it is mentioned in later seasons that he still goes to support meetings.]]

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* ''Series/CriminalMinds'' has perhaps the ''[[{{Deconstruction}} darkest]]'' take on this trope anywhere, when [[TheWoobie Reid]] is kidnapped by a man with three personalities: His abusive father, the angel Raphael, and the man himself, Tobias, who is meek and afraid of the others. After the first two torture Reid, Tobias gives him his own personal drug blend to help with the pain...and [[UnwittingInstigatorOfDoom ends up causing more trouble than the other two combined]], [[RealityEnsues [[SurprisinglyRealisticOutcome since Reid becomes addicted. He has to struggle to get clean and it is mentioned in later seasons that he still goes to support meetings.]]
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* ''Series/{{Ramy}}'': In the third episode, Ramy impulsively takes an entire CBD gummy (well above the recommended intake amount, especially for someone who has never done drugs) meant as a painkiller for his friend Steve, and spends the rest of the episode high.
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* In ''Film/LooseScrews'', Miss Von Blow, the matriarch of the girls' dorm at Cockswell Academy, takes one of the joints from the girls and starts smoking it, thinking it's a "Turkish blend" cigarette, and eventually gets her orders for the girls all mixed up in the process.

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