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* Colress from ''VideoGame/PokemonBlack2AndWhite2'' is a MadScientist obsessed with [[INeedYouStronger discovering the limits to the strength of Pokémon]] and becomes TheDragon to [[BigBad Ghetsis]] to take advantage of Team Plasma's resources while helping them weaponize the [[OlympusMons legendary dragon Kyurem]]. However, he was ultimately a PunchClockVillain and becomes TheAtoner after Ghetsis' defeat upon realizing he was going about it the wrong way.
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* In ''VideoGame/{{Palworld}}'', the FinalBoss Victor Ashford is a MadScientist in an EerieArcticResearchStation who seeks to use the game's {{mon}}s to create {{Bioweapon Beast}}s, with his partner Shadowbeak being [[UltimateLifeForm his first success]]. While the game is an AffectionateParody of ''Franchise/{{Pokemon}}'' rife with BlackComedy directed at the mons, Victor's PlayingWithSyringes is decidedly ''not'' PlayedForLaughs as he speaks of them in a cold, clinical tone through his journals. He melted them down into slurry that was fed to their fellow Pals, merged them together in horrifying ways and discarded them when the results failed to live more than a few seconds, and generally tore into them just to find out how they ticked.
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* ''Literature/SpaceTrilogy'': Professor Weston develops interplanetary travel so humanity and their descendants (whatever they evolve into) could go out into the stars and survive throughout the cosmos. However, Weston doesn't care that this plan may involve wiping out other intelligent life. (In the second book, he abandons this goal in favor of a New Age-y philosophy he dubs "Spiritual Evolution", which has nothing to do with this trope.) The trope is taken further in the third book, where the N.I.C.E. plans to replace all organic life with a machine life.

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* ''Literature/SpaceTrilogy'': ''Literature/TheSpaceTrilogy'': In [[Literature/OutOfTheSilentPlanet the first book]], Professor Weston develops interplanetary travel so humanity and their descendants (whatever they evolve into) could go out into the stars and survive throughout the cosmos. However, Weston doesn't care that this plan may involve wiping out other intelligent life. (In [[Literature/{{Perelandra}} the second book, book]], he abandons this goal in favor of a New Age-y philosophy he dubs "Spiritual Evolution", which has nothing to do with this trope.) The trope is taken further in [[Literature/ThatHideousStrength the third book, where book]], in which the N.I.C.E. plans to replace all organic life with a machine life.



* ''Literature/{{Tarzan}}'': In ''Tarzan and the Lion-Man'', "God" was an English MadScientist who came to Africa to conduct genetic and evolutionary experiments on gorillas. He rejuvenated himself with gorilla genes, but gradually assumed their physical characteristics.

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* ''Literature/{{Tarzan}}'': In "God" from ''Tarzan and the Lion-Man'', "God" was Lion-Man'' is an English MadScientist who came to Africa to conduct genetic and evolutionary experiments on gorillas. He rejuvenated himself with gorilla genes, but gradually assumed their physical characteristics.

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** ''ComicBook/TheIncredibleHulk'' villain the Leader is a man granted super-intelligence by gamma radiation. Among his various obsessions is that he wants to create more gamma mutates, and he has repeatedly launched schemes to expose the public to gamma radiation, hoping that the few survivors would develop powers. He successfully gamma bombed a little town and did wind up with a handful of new mutates, along with a whole town full of dead innocent people.



** ComicBook/TheIncredibleHulk's enemy the Leader is a man granted super-intelligence by gamma radiation. Among his various obsessions is that he wants to create more gamma mutates, and he has repeatedly launched schemes to expose the public to gamma radiation, hoping that the few survivors would develop powers. He successfully gamma bombed a little town and did wind up with a handful of new mutates, along with a whole town full of dead innocent people.
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** The ComicBook/IncredibleHulk's enemy the Leader is a man granted super-intelligence by gamma radiation. Among his various obsessions is that he wants to create more gamma mutates, and he has repeatedly launched schemes to expose the public to gamma radiation, hoping that the few survivors would develop powers. He successfully gamma bombed a little town and did wind up with a handful of new mutates, along with a whole town full of dead innocent people.

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** The ComicBook/IncredibleHulk's ComicBook/TheIncredibleHulk's enemy the Leader is a man granted super-intelligence by gamma radiation. Among his various obsessions is that he wants to create more gamma mutates, and he has repeatedly launched schemes to expose the public to gamma radiation, hoping that the few survivors would develop powers. He successfully gamma bombed a little town and did wind up with a handful of new mutates, along with a whole town full of dead innocent people.
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* ''VideoGame/{{Fallout}}'':

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* ''VideoGame/{{Fallout}}'':''Franchise/{{Fallout}}'':
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** The ComicBook/IncredibleHulk's enemy the Leader is a man granted super-intelligence by gamma radiation. Among his various obsessions is that he wants to create more gamma mutates, and he has repeatedly launched schemes to expose the public to gamma radiation, hoping that the few survivors would develop powers. He successfully gamma bombed a little town and did wind up with a handful of new mutates, along with a whole town full of dead innocent people.
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* ''Fanfic/TheGreatRedPandaRescue'': Mei is [[KidnappedForExperimentation kidnapped by scientists]] who want to learn how her panda powers work.

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* ''Fanfic/TheGreatRedPandaRescue'': Mei [[WesternAnimation/TurningRed Mei]] is [[KidnappedForExperimentation kidnapped by scientists]] who want to learn how her panda powers work.

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* Dr. Octopus is this in ''WesternAnimation/TheSpectacularSpiderMan'' and its successor ''WesternAnimation/UltimateSpiderMan''. In the former, he's been recruited to assist a shady organization with their genetic experimentation by turning criminals/hired thugs into enhanced super humans. In the latter, he starts out working for Norman Osborn to replicate Spider-Man's powers, leading to the creation of Venom, [[spoiler: the Green Goblin, the Lizard, the Rhino, etc]].
* ''WesternAnimation/StreetSharks'': Dr. Paradigm starts out like this, as evidenced by his monologue about how great his human test subjects will be post-transformation and sans those silly human morals. He abandons that pretty early and switches to simply taking over the town/world though. This is after getting a taste of his own medicine makes him seven kinds of AxCrazy, though.
* ''WesternAnimation/TeenageMutantNinjaTurtles2012'': The Kraang are either directly or indirectly responsible for every mutant created in the series due to their creating the mutagen that started it all. While some of their "creations" escape (i.e. Splinter and the baby!Turtles), many of them are kept prisoner and experimented on (like Leatherhead).

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* In ''WesternAnimation/TheSpectacularSpiderMan'', Dr. Octopus Octavius (who eventually becomes Dr. Octopus) is this in ''WesternAnimation/TheSpectacularSpiderMan'' and its successor ''WesternAnimation/UltimateSpiderMan''. In the former, he's been recruited to assist a shady organization with their genetic experimentation by turning criminals/hired thugs into enhanced super humans. In the latter, he starts out working for Norman Osborn to replicate Spider-Man's powers, leading to the creation of Venom, [[spoiler: the Green Goblin, the Lizard, the Rhino, etc]].
superhumans.
* ''WesternAnimation/StreetSharks'': Dr. Paradigm starts out like this, as evidenced by his monologue about how great his human test subjects will be post-transformation and sans those silly human morals. He abandons that this goal pretty early and switches to simply taking over the town/world though.town/world. This is after getting a taste of his own medicine makes him seven kinds of AxCrazy, though.
* ''WesternAnimation/TeenageMutantNinjaTurtles2012'': The Kraang are either directly or indirectly responsible for every mutant created in the series due to their creating the mutagen that started it all. While some of their "creations" escape (i.e. , Splinter and the baby!Turtles), baby Turtles), many of them are kept prisoner and experimented on (like Leatherhead).


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* In ''WesternAnimation/UltimateSpiderMan2012'', Dr. Octopus starts out working for Norman Osborn to replicate Spider-Man's powers, leading to the creation of Venom, [[spoiler:the Green Goblin, the Lizard, the Rhino, et cetera]].
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* ''VideoGame/DeadSpace'' features two {{Mad Scientist}}s; one relatively helpful and benign despite his insanity, and one who is more clearly villainous. The evil one is an evilutionary biologist, and more than happy to sic his nigh-invulnerable genetically engineered super monster on you.

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* ''VideoGame/DeadSpace'' ''VideoGame/DeadSpace1'' features two {{Mad Scientist}}s; one relatively helpful and benign despite his insanity, and one who is more clearly villainous. The evil one is an evilutionary biologist, and more than happy to sic his nigh-invulnerable genetically engineered super monster on you.
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* ''Fanfic/HonorTrip'': [[MadScientist Ratsura]] plays this trope straight as an arrow, [[DepravedBisexual though he himself]] [[AxeCrazy is not straight]] [[JustForPun in the least.]]

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* ''Fanfic/HonorTrip'': [[MadScientist Ratsura]] plays this trope straight as an arrow, [[DepravedBisexual though he himself]] he]] himself [[AxeCrazy is not straight]] [[JustForPun in [[{{Pun}} the least.]]
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* ''Fanfic/{{Spider-Ninja}}'': [[spoiler: Dr. Connors]] has shades of this from the moment he appears, and admits that he finds the Turtles and Petra "fascinating". He's a more sympathetic version than most examples here, as he dabbles in modifying human DNA because he wants to find a way to regrow his lost arm. However, by the end [[spoiler: the narrative reveals that [[InSpiteOfANail he's been trying to create a serum based on modified animal DNA to regrow his lost arm]]. He resorts to [[OrganTheft stealing a blood sample from Raph]] to further his experiments. The ending heavily implies that he'll use the sample to [[DoomedByCanon become the Lizard]].]]

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* ''Fanfic/TheGreatRedPandaRescue'': Mei is [[KidnappedForExperimentation kidnapped by scientists]] who want to learn how her panda powers work.



* ''Fanfic/{{Spider-Ninja}}'': [[spoiler: Dr. Connors]] has shades of this from the moment he appears, and admits that he finds the Turtles and Petra "fascinating". While he manages to keep his curiousity in check, by the end [[spoiler: the narrative reveals that [[InSpiteOfANail he's been trying to create a serum based on modified animal DNA to regrow his lost arm]]. He resorts to [[OrganTheft stealing a blood sample from Raph]] to further his experiments. The ending heavily implies that he'll use the sample to [[DoomedByCanon become the Lizard]].]]

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* ''Fanfic/{{Spider-Ninja}}'': [[spoiler: Dr. Connors]] has shades of this from the moment he appears, and admits that he finds the Turtles and Petra "fascinating". While He's a more sympathetic version than most examples here, as he manages dabbles in modifying human DNA because he wants to keep find a way to regrow his curiousity in check, lost arm. However, by the end [[spoiler: the narrative reveals that [[InSpiteOfANail he's been trying to create a serum based on modified animal DNA to regrow his lost arm]]. He resorts to [[OrganTheft stealing a blood sample from Raph]] to further his experiments. The ending heavily implies that he'll use the sample to [[DoomedByCanon become the Lizard]].]]
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** Unlike most Genestealer Cults, the Cult of the Twisted Helix was created by the deliberate machinations of its human subjects. The scientists and researchers of the medical-industrial world Vejovium III were able to produce a serum from the dissection and study of captive Genestealers that they believed would allow them to achieve immortality and biological perfection. The original batches of the serum simply transformed their test subjects into Genestealer hybrids, but the cult's leadership, now long-since transformed into equivalents of magi and biophagi, continues to experiment and seek true perfection. Most of their experiments result in their test subjects becoming twisted monsters -- aberrants, metamorphs and more unique horrors -- that are put to use as shock troops to fuel the cult's hunger for resources and fresh guinea pigs.
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Regardless, because of his dedication, the Evilutionary Biologist is willing to break laws, engage in [[PlayingWithSyringes experimental alterations upon other human beings]], and ruin lives for [[UtopiaJustifiesTheMeans the higher goal]]. Their creations are no less exempt; whether they're ReplacementGoldfish, with CloneAngst, or genetically "programmed" to have [[VillainousLineage evil]], their "children" are doomed to live sad, short, [[TurnedAgainstTheirMasters rebellious]] lives, unless they really ''do'' feel [[TrulySingleParent parental]]. They will never realize that EvilEvolves and will never be able to identify themselves as the villains.

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Regardless, because of his dedication, the Evilutionary Biologist is willing to [[KidnappedForExperimentation break laws, laws]], engage in [[PlayingWithSyringes experimental alterations upon other human beings]], and ruin lives for [[UtopiaJustifiesTheMeans the higher goal]]. Their creations are no less exempt; whether they're ReplacementGoldfish, with CloneAngst, or genetically "programmed" to have [[VillainousLineage evil]], their "children" are doomed to live sad, short, [[TurnedAgainstTheirMasters rebellious]] lives, unless they really ''do'' feel [[TrulySingleParent parental]]. They will never realize that EvilEvolves and will never be able to identify themselves as the villains.
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* ''Fanfic/{{Spider-Ninja}}'': [[spoiler: Dr. Connors]] has shades of this from the moment he appears, and admits that he finds the Turtles and Petra "fascinating". While he manages to keep his curiousity in check, by the end [[spoiler: the narrative reveals that [[InSpiteOfANail he's been trying to create a serum based on modified animal DNA to regrow his lost arm]]. He resorts to [[OrganTheft stealing a blood sample from Raph]] to further his experiments. The ending heavily implies that he'll use the sample to [[DoomedByCanon become the Lizard]].]]


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* The scientists of ''WesternAnimation/TheSecretOfNimh'' knowingly injected several dozen rodents with a serum that gave them human-level intelligence for the purpose of medical research (meaning that they were likely [[FridgeHorror going to kill the rodents via experimentation]]). Good thing they escaped.
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* Dr. Octopus is this in ''WesternAnimation/TheSpectacularSpiderMan'' and its successor ''WesternAnimation/UltimateSpiderMan''. In the former, he's been recruited to assist a shady organization with their genetic experimentation by turning criminals/hired thugs into enhanced super humans. In the latter, he starts out working for Norman Osborn to replicate Spider-Man's powers, leading to the creation of Venom, [[spoiler: the Green Goblin, the Lizard, the Rhino, etc]].


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* ''WesternAnimation/TeenageMutantNinjaTurtles2012'': The Kraang are either directly or indirectly responsible for every mutant created in the series due to their creating the mutagen that started it all. While some of their "creations" escape (i.e. Splinter and the baby!Turtles), many of them are kept prisoner and experimented on (like Leatherhead).
* ''WesternAnimation/TransformersPrime'': MECH wanted to steal the deadliest technology available so they could further their goals of remaking the world in their image. As such, they become ''very'' interested in the Cybertronians when they learn of their existence. This leads to their kidnapping/trying to dissect Breakdown, almost gutting Arcee, [[OrganTheft stealing Bumblebee's and Starscream's T-cogs]], and creating Nemesis Prime (a remote-controlled Cybertronian with the power of Optimus Prime). They cross the MoralEventHorizon when they [[spoiler: put Silas' barely alive body inside and basically turn him into a human-Cybertronian hybrid]]. You know a group is bad when both the Autobots ''and'' [[EveryoneHasStandards the Decepticons]] hate them.
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** ''VideoGame/ResidentEvil5'' takes it to a new level with Project W. Ironically, this was one of the ''first'' projects Umbrella started in the timeline. Umbrella founder Ozwell Spencer envisioned the rise of a superior breed of humans [[spoiler:(consisting of humans infused with the Progenitor Virus at a young age)]] indoctrinated with his own SocialDarwinist values and presumably his interest in biological studies. In other words, this was an Evilutionary project ''to manufacture more Evilutionary Biologists''. Fortunately, the project was ultimately a failure since [[spoiler:Albert Wesker and his sister Alex Wesker were the only children to survive the virus injections all the other Wesker children received]].

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** ''VideoGame/ResidentEvil5'' takes it to a new level with Project W. Ironically, this was one of the ''first'' projects Umbrella started in the timeline. Umbrella founder Ozwell Spencer envisioned the rise of a superior breed of humans [[spoiler:(consisting of humans infused with the Progenitor Virus at a young age)]] indoctrinated with his own SocialDarwinist [[TheSocialDarwinist Social Darwinist]] values and presumably his interest in biological studies. In other words, this was an Evilutionary project ''to manufacture more Evilutionary Biologists''. Fortunately, the project was ultimately a failure since [[spoiler:Albert Wesker and his sister Alex Wesker were the only children to survive the virus injections all the other Wesker children received]].
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* ''VideoGame/SuperCatboy'': Dr. Ungefog, the game's BigBad creates his personal army of hyper-obediant soldiers by experimenting on animals like cats and dogs. For some reason, cats are consderably on the "superior" side, with felines like the titular Catboy being reserved as SuperSoldiers.
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* In ''Literature/TheBeginningAfterTheEnd'', The Vritra Clan according to Windsom are considered an anomaly among asuras as they are scientists who are constantly studying insights on the workings of mana to evolove their mana arts.[[spoiler: After Agrona Vritra StartOfDarkness and becoming the BigBad of the story when he attempted to reveal the truth about the Djinn genocide committed by the Indrath clan regarding aether knowledge. Agrona began experimenting and interbreeding with all of Alacrya to get revenge against Kezess Indrath and all of the Epheotus for betraying and exiling him unjustly. Agrona's experiments lasted for a hundred generations resulted in creation of the wraiths, Vritra blooded Alacryans, scythes, retainers and a very powerful alacryan war machine making a case of a BadAssArmy and an averted case of CripplingOverSpecialization despite that it resulted in the death of many Alacryans as a failed experiments]].
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Regardless, because of his dedication, the Evilutionary Biologist is willing to break laws, engage in [[PlayingWithSyringes experimental alterations upon other human beings]], and ruin lives for [[UtopiaJustifiesTheMeans the higher goal]]. Their creations are no less exempt; whether they're ReplacementGoldfish, with the CloningBlues, or genetically "programmed" to have [[VillainousLineage evil]], their "children" are doomed to live sad, short, [[TurnedAgainstTheirMasters rebellious]] lives, unless they really ''do'' feel [[TrulySingleParent parental]]. They will never realize that EvilEvolves and will never be able to identify themselves as the villains.

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Regardless, because of his dedication, the Evilutionary Biologist is willing to break laws, engage in [[PlayingWithSyringes experimental alterations upon other human beings]], and ruin lives for [[UtopiaJustifiesTheMeans the higher goal]]. Their creations are no less exempt; whether they're ReplacementGoldfish, with the CloningBlues, CloneAngst, or genetically "programmed" to have [[VillainousLineage evil]], their "children" are doomed to live sad, short, [[TurnedAgainstTheirMasters rebellious]] lives, unless they really ''do'' feel [[TrulySingleParent parental]]. They will never realize that EvilEvolves and will never be able to identify themselves as the villains.



* ''Anime/MagicalGirlLyricalNanohaStrikers'': Dr. Jail Scaglietti, the MadScientist behind [[CloningBlues Project F]] and several other ArtificialHuman related experiments. According to [[SmugSnake Quattro]], his ultimate goal is the completion of biomanipulation technology and the creation of a space to do that. That at least several hundred thousand people would die in the process is acceptable collateral damage.

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* ''Anime/MagicalGirlLyricalNanohaStrikers'': Dr. Jail Scaglietti, the MadScientist behind [[CloningBlues Project F]] F and several other ArtificialHuman related experiments. According to [[SmugSnake Quattro]], his ultimate goal is the completion of biomanipulation technology and the creation of a space to do that. That at least several hundred thousand people would die in the process is acceptable collateral damage.
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* ''Film/GuardiansOfTheGalaxyVol3'': The High Evolutionary is such a heinous villain because of how he experiments on any living organism to create the "perfect species". Some notable despicable acts he committed include torturing a young Rocket Raccoon, creating a machine that causes animals to rapidly (and painfully) evolve into sentient anthropomorphized beings and destroying an entire planet of his own living creations because of their imperfections.

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* ''Literature/VorkosiganSaga'': The Cetagandan haut [[FantasticCasteSystem caste]], especially the women, are basically running a very long-term genetic engineering project to turn themselves into TranshumanAliens.



* ''Literature/VorkosiganSaga'': The Cetagandan haut [[FantasticCasteSystem caste]], especially the women, are basically running a very long-term genetic engineering project to turn themselves into TranshumanAliens.

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* ''Literature/VorkosiganSaga'': The Cetagandan haut [[FantasticCasteSystem caste]], especially ''Literature/XWingSeries'': Dr. Edda Gast was a biologist working at Project Chubar "humanizing" alien species so Zsing could make use of them as minions. This involves tortuously altering them to "improve" them against their will. While the women, are basically running a very long-term genetic engineering project uncle, who originally led the project, had eventually [[DrivenToSuicide killed himself in guilt]] along with his favorite subjects after coming to turn themselves into TranshumanAliens.love them, Gast feels absolutely no remorse. Indeed, she never displays any caring [[TheSociopath for anyone else at all]].
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* ''Literature/ACertainMagicalIndex'': Creator/AleisterCrowley ([[BeethovenWasAnAlienSpy yes, that one]]) is, in this universe, the founder and leader of [[{{Tomorrowland}} Academy City]], a scientifically advanced city located within Tokyo that is comprised mostly of students. Said students are [[DifferentlyPoweredIndividual espers]] whose studies are mainly focused on the development of PsychicPowers, which they gain through a combination of drug treatment and hypnosis, and the usefulness of which are ranked from [[PowerLevels Levels]] [[WhatKindOfLamePowerIsHeartAnyway 1]] through [[PersonOfMassDestruction 5]]. Every esper is essentially a human guinea pig in a massive citywide experiment conducted by the scientists that run Academy City, who range from the [[ForScience amoral]] to the downright [[MadScientist insane]] (the Kihara family), and Aleister himself [[spoiler: is a former magician who turned his back on magic after growing disillusioned with a world in which humans allowed their destiny to be controlled by the magical "phases" that can affect a person's fortune. It's implied that his ultimate goal for the espers is to use the unique energy they unconsciously emit, known as [[AppliedPhlebotinum AIM fields]], to rid the world of magic, which he believes will direct humanity towards its ideal course in which people are freed from fate and mysticism, and the world is built up from the efforts of individuals rather than that of [[RageAgainstTheHeavens the gods]]]].

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* ''Literature/ACertainMagicalIndex'': Creator/AleisterCrowley ([[BeethovenWasAnAlienSpy yes, that one]]) is, in this universe, the founder and leader of [[{{Tomorrowland}} Academy City]], a scientifically advanced city located within Tokyo that is comprised mostly of students. Said students are [[DifferentlyPoweredIndividual espers]] whose studies are mainly focused on the development of PsychicPowers, which they gain through a combination of drug treatment and hypnosis, and the usefulness of which are ranked from [[PowerLevels Levels]] [[WhatKindOfLamePowerIsHeartAnyway 1]] through [[PersonOfMassDestruction 5]]. Every esper is essentially a human guinea pig in a massive citywide experiment conducted by the scientists that run Academy City, who range from the [[ForScience amoral]] to the downright [[MadScientist insane]] (the Kihara family), and Aleister himself [[spoiler: is [[spoiler:is a former magician who turned his back on magic after growing disillusioned with a world in which humans allowed their destiny to be controlled by the magical "phases" that can affect a person's fortune. It's implied that his ultimate goal for the espers is to use the unique energy they unconsciously emit, known as [[AppliedPhlebotinum AIM fields]], to rid the world of magic, which he believes will direct humanity towards its ideal course in which people are freed from fate and mysticism, and the world is built up from the efforts of individuals rather than that of [[RageAgainstTheHeavens the gods]]]].



** ''VideoGame/BioShock2'' has [[KnightTemplar Sofia Lamb]]. An insane Altruist, her life experiences [[spoiler:(and the events of the first game)]] led her to believe that [[TheEvilsOfFreeWill free will is a evolutionarily conditioned illusion]]. In order to release Rapture from the "burden" of self-awareness, she's decided to [[spoiler: ''[[AssimilationPlot fuse all its people into a single, non-aware being using the body of her own daughter]]]]'', believing the result will be a "[[UtopiaJustifiesTheMeans True Utopian]]".

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** ''VideoGame/BioShock2'' has [[KnightTemplar Sofia Lamb]]. An insane Altruist, her life experiences [[spoiler:(and the events of the first game)]] led her to believe that [[TheEvilsOfFreeWill free will is a evolutionarily conditioned illusion]]. In order to release Rapture from the "burden" of self-awareness, she's decided to [[spoiler: ''[[AssimilationPlot ''[[spoiler:[[AssimilationPlot fuse all its people into a single, non-aware being using the body of her own daughter]]]]'', believing the result will be a "[[UtopiaJustifiesTheMeans True Utopian]]".



* ''WesternAnimation/ActionMan2000'': Doctor X is a textbook Evilutionary Biologist obsessed with triggering the [[EvolutionaryLevels next step in human evolution]] by causing all sorts of disasters in the hopes of culling unfit humans and cause beneficial mutations in the survivors.

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* ''WesternAnimation/ActionMan2000'': Doctor X is a textbook Evilutionary Biologist obsessed with triggering the [[EvolutionaryLevels next step in human evolution]] by causing all sorts of disasters in the hopes of culling unfit humans and cause causing beneficial mutations in the survivors.
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** In ''ComicBook/ScareTactics'', Slither was experimented on by his biologist father with the result that he transformed into a LizardFolk.

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** In ''ComicBook/ScareTactics'', ''ComicBook/ScareTacticsDCComics'', Slither was experimented on by his biologist father with the result that he transformed into a LizardFolk.
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* [[spoiler:Sanji's father]] Vinsmoke Judge from ''Manga/OnePiece''. He rules a kingdom with an iron fist and is very abusive to his son [[spoiler:Sanji]]. [[spoiler:He specializes in CreatingLife and genetically engineering humans at the peak of physical prowess. Not to mention he modified his own children to become SuperSoldier {{Tyke Bombs}}s with the cost of their human emotions and empathy.]]

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* [[spoiler:Sanji's father]] Vinsmoke Judge from ''Manga/OnePiece''. He rules a kingdom with an iron fist and is very abusive to his son [[spoiler:Sanji]]. [[spoiler:He specializes in CreatingLife and genetically engineering humans at the peak of physical prowess. Not to mention he modified his own children to become SuperSoldier {{Tyke Bombs}}s Bomb}}s with the cost of their human emotions and empathy.]]
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->''[[Music/ThePolice Oh, can't you see/You've got subpar genes/How the planet aches/From every breath you take...]]''
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* ''VideoGame/{{Warframe}}'': [[WickedCultured Tyl Regor]] is the lead geneticist of the [[CloneArmy Grineer Empire]], working to solve the Grineers' major problem with CloneDegradation. He is fiercely protective of his "Tubemen" project, the intended next step in Grineer evolution, lacking the genetic weaknesses of clone rot or aging. Early fruits of his labor can be seen in the Grineer Manics, dangerous lunatics that are ''significantly'' more agile than your common Grineer grunt and employ TeleportSpam.
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* ''ComicBook/HybridForce'': [[BigBad Dr. Insomnia]] is a MadScientist and leader of the terrorist organization Testify. He abducted numerous people and genetically altered them into [[HalfHumanHybrid plant/animal people]] to help him in his plans to TakeOverTheWorld.

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