History Main / DiseaseBleach

* [[DaChief Hyoue Kuroda]] from Manga/CaseClosed is fully grey despite [[YoungerThanTheyLook only being 50]] for the same reason he's [[EyeScream missing an eye]], having spent a decade in a coma following a severe accident (specifically [[spoiler: getting t-boned by a truck while fleeing from [[TheSyndicate The Black Organization]]).]]

* In the second ''Manga/{{Gintama}}'' movie, Be Forever Yorozuya, there is an outbreak of a disease called the White Plague, and one of the symptoms is that the hair goes white. This happens to [[spoiler: Shimura Otae, who is implied to have died before the timeline reset.]] Also, [[spoiler: Sakata Gintoki, whose hair is normally silver, turns completely white due to being the host of this disease.]]
* In ''Literature/HalfPrince'', [[spoiler: Long Dian's]] hair has turned white, apparently due to his life-threatening disease. [[spoiler: He regains black hair when he gets a synthetic body.]]

** This happens to in Part 4 to Yukako Yamagishi when she uses her [[FightingSpirit Stand]] [[PrehensileHair Love Deluxe]] too much or if she takes too much damage.
** In the ''Stardust Crusaders'' anime adaptation, this happens to [[spoiler: D'Arby]] during his VillainousBreakdown.
* In ''Manga/{{Naruto}}'', this happens to [[spoiler:Nagato]] when he [[spoiler: uses the Outer Path - Samsara of Heavenly Life Technique to bring BackFromTheDead everyone he killed when he invaded Konoha]]: the strain causes his hair to go white before [[RedemptionEqualsDeath he dies]]. [[spoiler: Kabuto later revives him with Impure World Reincarnation, and Nagato's hair is still white, that is until he absorbs some of Killer B's chakra, causing his hair to turn red again.]]

* ''Manga/TokyoGhoul'': After enduring ten days of ColdBloodedTorture at the hands of [[TortureTechnician Yamori]], Kaneki's hair turns white from the trauma.

* The title character of ''ComicBook/{{XIII}}'' has a grey streak on his left temple where a bullet scratched him pre-amnesia.

* Cleo of Wetmoon has her hair fall out and once it regrows it's white.

* ''Film/{{It|1990}}'': Henry Bowers's brown hair turns white and he is driven insane after seeing IT's true form.

* ''Film/{{Se7en}}'': Victor, the Sloth victim, has suffered this alongside a mess of other BodyHorror, his brunette hair turning grayish-white inside just a year.

* In Bram Stoker's ''Literature/{{Dracula}}'', Jonathan's hair begins to go grey after his imprisonment at the Count's castle. It's believed by some to be another way in which he grows to mirror Dracula himself, similar to his personality change and growing fixation on his weapons. Of course, this gets even more patently ridiculous later on: after Mina explains all the deprivations the Count has been secretly putting her through and the fact that he's setting her up to become another vampire thrall, Jonathan's hair is ''explicitly'' stated as going stark white right then and there, [[ArtisticLicenseBiology grown hair and all]].

* Literature/TheTalmud discusses a Jewish scholar whose hair turned white at the age of 17 due to him being overworked.

* ''Series/DoctorWho'': In [[Recap/DoctorWhoS30E17E18TheEndOfTime "The End of Time"]], [[spoiler:the Master's]] hair [[LockedIntoStrangeness turns white]] following a sabotaged [[CameBackWrong resurrection]]. He happens to be slowly dying, exacerbated by CastFromLifespan superpowers that his HorrorHunger cannot entirely deal with.
* On ''Series/IZombie'', one of the first signs of someone becoming a zombie is their hair turning white, followed by their skin.

[[caption-width-right:350:[[Literature/{{Dracula}} Jonathan Harker]], before and after a stay at the Castle of {{Dracula}}.]]

* ''WesternAnimation/TheDragonPrince'': This seems to be one of the early consequences of TheCorruption caused by DarkMagic. Claudia develops a streak of white hair after [[spoiler:sacrificing a fawn to heal her brother's paralysis]]. Later, [[spoiler:half her hair turns white after bringing her father BackFromTheDead]].

* In ''Manga/OnePiece'', Hody Jones and his crew had their hair turn white after overdosing on energy steroids, giving them a large power boost, but shortening their lifespans.