It inspired following writers to give their stories a Darker and Edgier tone. Then again, Chip 'n Dale: Rescue Rangers' canonical setting begged for darker and more intense stories.
Also, it introduced Chip and Dale's fanonical last names that many Rangerphiles have adopted ever since, including in Fan Fiction.
Memetic Mutation: At the fan forum The Acorn Cafe, there is a meme created by 8-Bit Star that states that certain things have been "invented by Ivana M. Killjoy to distract us while she kills the Rangers."
One-Scene Wonder: Rhyme and Reason brings back many one-shot characters from the show. It actually differs from later CDRR fanfics in that it doesn't feature the famous Ensemble Darkhorses like Foxglove or Tammy a lot, if at all, while including characters never to be seen again in fanfic.
Tough Act to Follow: Early Rangerphiles thought they could impossibly write anything even close to Rhyme and Reason, so they didn't write anything at all until the next CDRR fanfic that was published turned out vastly different. That said, Rhyme and Reason did rake in Golden Acorn Awards for Best All-Time Fanfic (tying with Of Mice and Mayhem ever since that one was released) for almost as long as it was eligible.