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  • Alternative Character Interpretation: Is Dr. Akalitus being too harsh on Jackie in her diversion program? Or just being extra careful in case Jackie doesn't steal drugs again?
  • Diagnosed by the Audience:
    • Zoey Barkow's behavior, especially in the earlier seasons, implies that she might possibly be on the Autism Spectrum. She frequently doesn't pick up on social cues, is very eccentric and socially awkward.
    • Coop acts like a total Manchild, despite being an accomplished doctor in his 40s.
    • In early seasons, Grace Peyton has an intense anxiety disorder.
    • Fiona Peyton appears to be developmentally delayed, and also starts a fire at school.
  • Moral Event Horizon:
    • May not fully cross it, but baiting your sponsor into joining you in rehab, getting her drunk after being sober for 10 years, then revealing that you signed HER into rehab to get her out of the way has to at least come damn close.
    • Jackie's home detox a few episodes prior might also qualify. She puts boyfriend Frank, ex-boyfriend Eddie, and her sponsor through five days of hell as she kicks. At the end of the experience, sober at last, she boots Frank out of the house and rails a capsule of Oxycontin. The entire thing was a Batman Gambit to allay her friends' suspicions.
  • Squick: It takes place in a Trauma Unit, so most every episode has a degree of this, however, a recent unexpected example would have been Thor removing his glass eye for Jackie. Somewhat more disconcerting when you realize this isn't special effects, either.
  • Too Bleak, Stopped Caring: Seasons 6 and 7 may be too bleak for some to care.

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