- Jerkass Woobie: Bill is an arrogant jerk who's emotionally reserved to the extreme, but he also had a pretty abusive childhood, is legitimately trying to make the world a better place and suffers pretty severe backlash to an overall benevolent study.
- Les Yay: Libby and Virginia. In the season 3 premier, they get into bed together, have a heart-to-heart, hold hands, and even kiss.
- Seasonal Rot: Season 1 was very well received. Season 2 started great, but after the time skip the show started to focus on plotlines too distant from the study that serves as the show's premise, such as Austin becoming a diet pill salesman, or Betty and Helen's attempt to have a baby (though, such plotlines were already present earlier in the show, with Dr. Depaul's cancer, which was seen as a high point of the show).
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