Juniper is the one who put out Anise's eye.
She's so self-destructive because she can't let go of her guilt. Ellie and Pumpkin are destined to become superheroes like Tarra.
At one point, Ellie reveals that the Fusion Dance with Tarra is how her (and Pumpkin's) breasts grew so big, and Rusche states in the FAQ that Pumpkin (and presumably Ellie) is literally becoming Tarra, or at least a replica thereof. Next time Tarra tangles with Tired Guy and his group of miscreants, she'll have reinforcements.