- What Could Have Been: The comic was originally going to be called The Pseudoscientists, and was very different from the comic we know and love today.
- Lanyon was originally much more antagonistic towards the Society, actively trying to shut them down.
- Jekyll and Frankenstein originally met when the former was nineteen and on an Arctic expedition.
- Whilst looking for Mr. Hyde, Rachel and Co. initially went to (female) Sherlock Holmes for help instead of Lucy.
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