- Blooper: Jennifer Hale is credited for Starfire, who doesn't speak, while she's uncredited for Killer Frost, who she did voice.
- Crossdressing Voices: Rachael MacFarlane as Billy Batson.
- Role Reprise:
- Tim Daly, Kevin Conroy, Clancy Brown, C.C.H. Pounder, and Jennifer Hale reprise their respective DC Animated Universe roles of Supermannote , Batman, Lex Luthor, Amanda Waller, and Killer Frost.
- In the French dub, several voice actors from previous adaptations reprised their roles here:
- From the Batman Film Series: Jacques Ciron as Alfred.
- From the DC Animated Universe: In addition to Alfred, Emmanuel Jacomy as Superman/Clark Kent.
- From The Batman: In addition to Alfred, Adrien Antoine as Batman/Bruce Wayne.
- From Batman: The Brave and the Bold: In addition to Batman, Paolo Domingo as Billy Batson and Thierry Murzeau as Gorilla Grodd.
- While Tim Daly had worked with Kevin Conroy and Clancy Brown before when they appeared in Superman: The Animated Series, this is his first time working with C.C.H. Pounder in a DC production as his involvement in the short-lived revival of The Fugitive forced him to be darrined by George Newbern as Superman for Justice League.
