- Disowned Adaptation: The real Patch Adams himself was dissatisfied with the film, saying that it is more commercial and focuses more on him being funny than his actual methods note . He was also annoyed that Robin Williams did not bother to donate any of his $21 million salary to his institute, although he did not dislike Williams as a whole and applauded his support for St. Jude Children's Hospital. In fact, the two were otherwise pretty good friends, so much so Adams would later write for Time Magazine a heartwarming farewell to Williams after he committed suicide.
- What Could Have Been: Tom Hanks was considered for the title role, but was busy shooting Saving Private Ryan and declined. Bill Murray was also considered.
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