The film
- California Doubling: The film is set in St. Petersburg, Florida. Filming took place in Savannah and Tybee Island, Georgia.
- Cast the Expert: The lecturer at the end of the film is played by Jordan Ellenberg, a mathematician and the film's mathematics consultant. He notes that the film cut his lecture and spliced two lines together to make what he was saying incorrect.
- Method Acting: Mckenna Grace actually memorized all the equations Mary writes in the film and didn't have to rely on off-camera notes or prompts for scenes where Mary is working at the blackboard.
- Romance on the Set: Chris Evans and Jenny Slate dated in real-life for some time after the filming of Gifted.
- Similarly Named Works: No relation to The Gifted (2017), an X-Men TV series by FOX, also released in 2017.