Tear Jerker / An American Tail: The Treasure of Manhattan Island

• While The Treasure of Manhattan Island doesn't really have any specific moments that will leave you bawling, it's a surprisingly depressing movie in its own right, tackling themes of racism, police brutality and sweatshops. It doesn't even have much of a happy ending. The underground Native Americans decide that Europeans are incapable of sharing the upper world with them (having witnessed Police Brutality and a race riot), so they seal off the main tunnel. And the villains behind it only get off with a slap on the wrist. The An American Tail universe really is a bit of a Crapsaccharine World.
• Fievel tearing up upon realizing just how horrible the Europeans were to the Native Americans, and feeling partly responsible (though his family only recently moved to the country).