Both the original movie and the sequel crop up here and there because of the absurdity of dragging a dead body by pretending it's still alive becoming iconic.
- Weekend at Bernie's is Rachel Green's favourite movie.
- It's also a favourite of the gang in How I Met Your Mother...
- One of Barney's "plays" (tricks he uses to try and get laid) is based on the fact that Bernie gets laid despite being dead. Barney also states at one point that in the event of his death he would like Ted and Marshall to take his body to the Hamptons and re-enact the movie (quite possibly in the hope of getting laid after dying).
- In "How Lily Stole Christmas", Ted references the sequel as a means of insulting Lily's sense of humour.Ted: Remember that time we heard her laughing, and we thought she was watching Weekend at Bernie's, but it turned out she was watching Weekend at Bernie's II!
- There's even an episode in season 8 called "Weekend at Barney's".
- Additionally, the Season 9 episode "Rally" has that "Weekend at Barney's" play, which is for the gang to put sunglasses on Barney's comatose & drunk body during the pre-wedding photos, and no-one would be the wiser. Barney was delighted to learn his friends actually pulled off "Weekend at Barney's" (or so they told him).
- The Goldbergs has Bill getting cold feet at his wedding and locking himself in the closet. Beverly threatens to drag his lifeless body to the altar and move his mouth to say "I do" if he doesn't come out to which Bill responds "You're gonna Weekend at Bernie's me?"
- An episode of Murdoch Mysteries (entitled "Weekend at Murdoch's") has Murdoch trying to catch an assassin by making it seem like one of his victims is still alive.
- In an episode of NCIS, a character who needs to establish an alibi is too embarrassed to say which film he was watching at the time in question. The team assumes he was watching porn, but he eventually admits that it was Weekend at Bernie's II.
- In The Office (US) episode "Grief Counseling", Michael Scott makes the Scranton employees attend a session talking about dealing with death, but no one else takes it seriously and tell fake stories about losing relatives that are mostly based on movies. Michael catches on when he realizes Kevin's story is retelling Weekend At Bernie's.
- In the Seinfeld episode "The Comeback", Elaine rents the sequel on video after Kramer recommends it. She's not impressed, resorting to shouting at her TV while watching it.Elaine: Bernie's dead, you morons!
- In "Doomcoming" from Yellowjackets, Shauna has killed her lover Adam and called him in her fellow Yellowjackets Natalie and Taissa, claiming he's the one who blackmailed them. Taissa says that they can't just leave him there and Shauna replies that they can't exactly Weekend at Bernie's him out the door either.
- The Angry Video Game Nerd: In his review of Greendog: The Beached Surfer Dude!, the Nerd describes the game's soundtrack as sounding like the Weekend at Bernie's soundtrack being played with trash cans and cheap kazoos.
- Climate Town: "It's Time To Let Coal Die
" starts with a Weekend at Bernies parody, comparing lugging around a corpse and pretending it's alive to trying to keep the coal industry alive by propping up the failing companies with taxpayer money instead of helping the miners get new jobs in actual renewables.
- The Amazing World of Gumball: A non-fatal occurrence in "The Ad" where the goats the Wattersons rented their house to pass out from shock but the family assumed they died. They decided to drag their bodies all across town, prop them up to look like they're enjoying themselves, take pictures of them for an album, and drop them off on a train back home so everyone will think they died of natural causes during the ride. The male goat was even named Bernie.
- In the Beavis and Butt-Head episode "Most Wanted", the main characters watch a trailer for Weekend at Bernie's Part 7, featuring a visibly decaying Bernie and the tag-line: "Bernie's still dead, and he's stiffer than ever!"
- In the Black Dynamite episode "The Shit That Killed the King or Weekend at Presley's" a morbidly obese and unhealthy Elvis Presley is sent to the black community as a special DEA agent and seemingly dies after biting into an unhealthy snack, forcing Black Dynamite's posse to move his body out of their territory and avoid being framed (since Nixon purposefully sent Elvis to die there and excuse a nuclear strike on black people). Elvis however turns out to be still alive, having just passed out from food coma.
- Looney Tunes Cartoons: In "Moody at the Movies", the Three Bears go to a theater to see Weekend at Daffy's.
- In The Oblongs episode "Bucketheads" Creepy Susie tells to a jerkass shop assistant: "Soon you will be dead, then we dig up your grave and make your corpse do embarrassing things, ala Weekend at Bernie's!"
- Regular Show: As referenced by the title, the plot of "Weekend at Bensons" has Modecai and Rigby making Benson look like he's alive (albeit really tired and not in the mood to talk) after their latest screw-up knocked him out cold.
- Rick and Morty: "Rixty Minutes" features a trailer for a movie Jerry Smith wrote and directed in another universe titled Last Will and Testimeow: Weekend at Dead Cat Lady's House II, the film's premise consisting of a spoof of Weekend at Bernie's where a Crazy Cat Lady dies and her cats subsequently move her corpse around to make it appear that she's still alive.
- Viciously parodied in Robot Chicken with a skit spoofing Hannah Montana. Hannah Montana is killed by a Loony Fan, and her friends try to protect her secret identity as Miley Cyrus by stealing her corpse to get her back to school for an important test. On the way they run into Lindsay Lohan, who drags them and Hannah's corpse on a ridiculous adventure. Eventually, Hannah's battered and ragged corpse is brought to school only for her dad to show up and reveal her identity. As Hannah's classmates mob her corpse to get an autograph, it gets thrown out the window and splatters on the sidewalk. The whole thing turns out to be a Disney Channel executive threatening a sobbing Miley Cyrus that they'll end her show like this if "she ever gets knocked up like that Zoey 101 whore."
- Rocko's Modern Life: In "Bye Bye Birdie", Rocko and Heffer are tasked with looking after Turdy, Filburt's pet bird, while Filburt goes to the hospital. Turdy dies after Heffer sits on him, but Heffer tries to convince Rocko that Turdy is still alive by dressing him in surfer clothes and spinning him on a record player.
- The Simpsons episode "Weekend at Burnsie's" takes its title from the movie and shares the same premise; Homer and Smithers believe that Mr. Burns has died and try to make it appear that he's still alive. Turns out, he's merely unconscious, not dead.
