Summaries of the comic's story arcs:
- "Cowardly Lion": A day in the life of the Project Skin Horse employees as they go to bring in a genetically-enhanced lion.
- "The Borrowers": Tip tries to make peace among the many forms of intelligent life that have developed in the office basement over several decades.
- "Wild Things": Unity urges Sweetheart to go on a destructive rampage.
- "I Can Fly": The team investigates the case of a military helicopter that used to be a video game nerd named Nick.
- "Dead Dogs"/"Big Bad Wolves": Tip is in charge of a mission to Alaska. Involves werewolves and sapient canids.
- "Tin Soldier": It appears to be Moustachio's turn to go on a rampage. Also features the return of Dr. Lee from "I Can Fly".
- "Brave Little Toasters": Gorgeous and FUNKY mad scientist brought in to repair Moustachio due to his breakdown from the events in Tin Soldier.
- "And All the Lovely Ladies": Tip and Konstantin must mud-wrestle. The ladies of SH gather to watch.
- "Come Swing From My Branches": The SH team is mobilized to serve notice to a Genius Loci, a sentient swamp.
- "If I Ran the Zoo": Unity and Nick are sent to investigate the mysterious fire at The Cypress, while Sweetheart and Tip go to a talking animal convention.
- "Once And Future": Unity wants to be a Notary Public, which coincidentally involves becoming part of an Ancient Order in Idaho, where Dr. Lee is looking into rogue robot sightings.
- "Choose" While Sweetheart deals with issues, two former acquaintances of Nick investigate his disappearance.
- "A Wrinkle in Time": A short guest-written story in which Dave Davenport's time machine goes wrong, and an infinite number of Arties try to steal Tip's dress.
- "Railway Children": SH and Anasigma (represented by Dr. Lee, Violet, and Sergio) are both invited to a mobile city of mad scientists and must compete to see which gets to represent them to the outside world.
- "My House Is Me": The team visits a disused amusement park with sapient animatronics, to try to get some answers about the Old War.
- "My Brother Sam is Dead": Dr. Lee perfects her brain-dispensing machine to improve human/zombie relations. Skin Horse escorts her to California, where Dead Rights legislation is being enacted.
- "The Terrible, Horrible, No Good, Very Bad Day": Skin Horse gets back from California to discover that Gavotte has gone stupid, and everyone needs the Basement Dweller files.
- "Grillo Parlante": The return of Jonah and Nera from "Choose", who now runs a conspiracy website.
- "Mixed-Up Files": Mr. Green does some exposition, Tigerlily Jones escapes from the Institute, and Skin Horse reforms to infiltrate A-Sig.
- "Looking Glass Land": The new Skin Horse gets organised and visits a parallel universe where "My Brother Sam" went differently.
- "Can't Catch Me": Ginny joins Skin Horse and goes on an entirely routine mission where nothing could possibly go wrong...
- "What Big Teeth": Sweetheart tries to get ready for a meeting.
- "Purple Waves": With the Department of Irradiation defunct, Chris and Marcie are given the chance to regain their irradiator, but they're not the only ones after it.
- "Yes, Virginia": Skin Horse has a Secret Santa to improve morale.
- "Fun for Some": Nick playtests the VR Whimsyworld, with the help of Baron Mistycorn and a familiar AI.
- "Ghosts I Have Been": A guest-written story in which Remy tries to help a spirit possessing an alligator.
- "Sure as You're Born": Skin Horse goes on an unofficial mission to support a vote for nonhuman rights, and discovers an old enemy is involved.
- "Unsinkable": Jonah and Nera investigate the fallout from the previous story and encounter Skin Horse, AG-I and a sea serpent.
- "The Hundred Dresses": Sweetheart uses drone technology to go on a date. It doesn't go well.
- "Angry at the Sky": Some kind of weather control threatens all Skin Horse's clients, and Mr Green is revealed.
- "Figgs and Phantoms": Mr. Green makes his move. Virginia finally learns what extirpation is.
- "The Iron Man": Tigerlily gets her mojo back and builds a really big robot.
- "Green Noah": Robot Fight Club.
- "Swiftly I Glide": The team infiltrates an A-Sig facility with surprising ease but conflicting mission goals.
- "A Life in the Woods": Tip finds himself on a new team with a familiar mission.
- "The Dreadful Future": Everyone's getting ominous dreams, but is that the real threat?
- "Muddled Wuddled Fuddled Duddled Fox": Renard has to pick a side.
- "The Lee of the Stone": A-Sig has a new target.
- "Off to the Fair": The team have to negotiate between Aimee, Tigerlily and Pavane.
- "Space-Bat-Angel-Dragon": Everything starts coming together, exactly as planned. Planned by who is another question.
- "Phantomwise": The grand finale!
