Offense
- Jeremy, God of Double Jumps (The Scout, Scoot, Scunt, Little Man, Ass Pancakes, Force of Nature) as a Intermediate God in the Hall of Abilities (House of Gaming)
- The Pyro, God(dess?) of Flamethrowers (W+M1 Pyro, That Thing/Freak, Buddy, The Butcher, Mute Freak) as an Intermediate God in the Hall of Ranged Weapons (House of Weapons)
Defense
- Mikhail, God of Gatling Guns (The Heavy Weapons Guy, The Heavy, Ivan, Misha, Fatty [by Scout], Hoovy, Fat Scout, Pootis, Stalingrad, The Russian) as an Intermediate God in the Hall of Firearms (House of Weapons)
- Dell Conagher, God of Percussive Maintenance (The Engineer, Engie) as an Intermediate God in the Hall of Technological Occupations (House of Machinery and Technology)
Support
- Mr. Ludwig, God of Top-Priority Target Healers (The Medic, Pocket Medic, Fritz Ludwig, The Undertaker [?]) as a Lesser God in the Hall of Physicians (House of Health and Diseases)
- Mick Mundy, God of Headshots (The Sniper, Mr. Mundy, Mun-dee, Sniper Rifle Guy, Australian Long-Shoot Man, Bruce, Cuntspam, Lucksman, Creditsman, The Hunter) as a Lesser God in the Hall of Methods of Killing (House of Slaughter)
- The Spy, God of Double-Reverse-Quadruple Agents (SPAH, SHPEE, Detective Jacques Murnau, The Detective, Corporal Detective Mannix, The Smoker) as a Demigod in the Hall of Traitor Archetypes (House of Betrayal and Treachery)
Non-Player Characters
- Saxton Hale, God of Australian Champions (Australian, CEO of Mann Co.Motto: , and The Man Who's Gonna Burn This Place to the Ground!) as an Intermediate God in the Hall of Nationality Archetypes (House of Cultures)
- Gray Mann, CEO of Money Spiders as an Intermediate God in the Hall of Currency (House of Commerce)
- Merasmus the Magician, Monoculus and the Horseless Headless Horsemann, The Triumvirate Gods of Damage Sponge Bosses (MERASMUS!, Wizard-Man, MONOCULUS!, HHH, Silas Mann) as Greater Gods in the Hall of Boss Design (House of Gaming)
