As a Moments subpage, all spoilers are unmarked as per policy. You Have Been Warned.
General
- It says something that the scariest parts of the series are its main protagonists. Take Crypto himself, a sadistic and genocidal nigh-unstoppable killing machine who is able to rip out the brain stems of humans, destroy entire towns and cities, and even manages to wipe out an entire government agency and alien race. Not to mention, he manages to become President of the United States in the end of the first game. If not for the game's over-the-top tone, he'd be terrifying.
- His weapons, too. He's able to anal probe people into ripping their brains out and has a Disintegrator Ray as one of his main arsenal. By Path of the Furon, Crypto can summon underground monsters to eat unsuspecting people, cause a meteor shower to land, pause time, summon black holes with a pistol, and even cause a tornado with his saucer. Way more terrifying in the hands of someone like Crypto than it sounds epic.
- Also keep in mind, Crypto is just one Furon, and he's capable of fighting the army to a standstill. Now picture a full invasion force.
- The reveal that Furons are only experimenting on and probing humans because Furon DNA has become damaged and sterile due to their use of atomic weaponry over the millennia and humans have pure Furon DNA in their genome. How? Because ancient Furons came to Earth after destroying Mars and "let off some steam" on the early human population.
Destroy All Humans!
- The fate of Miss Rockwell in the mission "Earth Women Are Delicious". Crypto hypnotizes her to run off into the woods, her dialogue implying that she's fully aware of what's happening to her but can't do anything to stop it. Crypto's dialogue (especially in the original version; the remake Bowdlerised it somewhat, but not entirely) implies that some of the experiments performed on her are sexual in nature. The newspaper epilogue reveals that she survived and was dumped back on Earth, but got thrown in an asylum afterwards.
- During "This Island Suburbia", Crypto opts to use the Jumbo Probe on an uncooperative Majestic agent. The agent's face face begins to drain and looks decomposed, outright turning grey in the remake. Crypto's commentary doesn't help as he really channels Jack Nicholson.Crypto: Hurts, don't it, monkey boy? You want it to stop, don't you? Then give Daddy what he needs.
Destroy All Humans! 2
- The intro shows Pox taunting a brain stem he's about to experiment on, implying that all the brains you've collected as DNA are still perfectly alive and aware until Pox is done with them.
- The Blisk, the true villains of the second game. Having been driven off Mars by the Furons many years ago, a few refugees crash-landed with their warship in Tunguska during 1908 in a supposed meteor crash. Having the ability to disguise as humans and with their native language being close to Russian, they managed to kickstart the 1917 Russian revolution and took complete control of the USSR. Their goal? To irradiate and waterlog the earth, using the Cold War to fuel the building of nuclear warheads, and wipe out humanity in the process. Even Pox is horrified to learn that they survived.
- Milenkov tells Crypto that every Premier before him (namely Vladimir Lenin, Joseph Stalin, but not Leon Trotsky) were all Blisk, while implying that they too used the Earth for "shore leave". They make Crypto look like a saint in comparison.
- Tunguska, the fourth region of the game where most of the plotline pieces together, is creepy in itself. The area is constantly dark and devoid of anything but green smog, with Red Army soldiers and KGB agents constantly walking the streets and shooting dead possible trespassers to their own base, and the gunfights between Blisk Mutants and security members on the streets. Not to mention how grimly fitting the music and the wolf howls in the area sounds.
- The fate of Sergei. After Milenkov captures Natalya off-screen, he mentions infecting him with spores, and that's the last we ever hear of him. Even after Crypto saves Natalya, neither of them bother to save him (then again, Milenkov mentions that trying to cure him wouldn't work), so he's left there to suffer from agony as most Blisk Mutants do.
- In fact, Sergei is one of the Blisk Mutants you have to fend off shortly after the cutscene. He can end up killed in any number of ways available to the player, without ever knowing that Sergei was there, or he can be Anal Probed and cured. At which point Sergei, being unarmed, likely within striking range of the other Blisk Mutants, and with the immediate area having scattered pockets of lethal radiation, is likely to die very quickly. Should Sergei survive, he'll simply run off into the distance without a word, never to be seen again.
- Reprobed shows the Blisk Mutant transformation scenes in far more detail. The spores rapidly cover the victim as their body distorts. The Blisk Mutants are significantly more terrifying here, being covered in green bulbous spores, a Slasher Smile with a forked tongue, and a skeletal body.
