In episode 5, Kirie shoves Yuuko aside with a "Get out of my way." Odd kind of interaction to be considered heartwarming, but this is the first time Kirie's acknowledged Yuuko directly, and they both reflect on it.
The Manga ends with Yuuko and Teiichi getting a mock marriage ceremony. Yuuko can leave the school now, so Keiichi can be with her for the rest of his life and beyond.