The number of editors Transmetropolitan had over the course of its run: 6. The number of skulls on sticks in front of Spider's house, helpfully labeled "These were editors": 6.
Transients are both biologically transient in the sense that their bodies are transitioning from one state to another, but the fact that the stigma against them forces them to the outskirts of society makes them cultural transients as well.
Spider wears a pair of shades with one slender rectangular lens and one round lens. Yelena wears shades with slender rectangular lenses and Channon wears shades with round lenses.
In the second volume, the group who shuns contact with the City mentions they like Spider's column. Of course they do! It's a confirmation that the City is just as bad as their Creed says. It's even titled "I Hate It Here"!
The final page of issue 33 has Spider pick up a dead bird from the ground and eat it. It's an odd thing to see (even in this universe) considering he's never done that before... except it fits his namesake: a lot of spiders do eat birds.
Why does Fred Christ never finish his transition? He spends the entire series half-human, half-Gray, while characters who have spent significantly less time as Transients are fully alien.
He not only never finishes his transition, he's very clearly half-human and half-gray with a neat line between the halves. That clean of a division is likely intentional and for symbolic reasons.
