The Mystery Case Files series adores its continuity nods, and it shows. Spanning 23 games plus several spinoffs and counting, seldom are the games that don't include any nod to previous games in the series, several games like Rewind or Moths to a Flame even being pure unadultered Continuity Porn.
- Prime Suspects:
- Vincent Gavone, another character from Prime Suspects, is said to be a member of a crime syndicate called S.T.A.I.N.. It is the organization the Master Detective disbanded in Huntsville.
- Several badges the Master Detective has earned during her time in Huntsville are among the hidden objects the player has to seek in the Auto Salvage.
- Madame Fate
- Art the Carny, from Madame Fate, is heavily implied to be Arthur Lugen, a character from Prime Suspects.
- Scribbled on the counter of one of the ticket office booths is the signature of Emma Ravenhearst from the previous game.
- When clicking too many times at random on the hidden object scenes, Madame Fate might scold the player with a "You're not in Huntsville anymore !".
- And, of course, there is the ending, which reveals that Madame Fate’s murderer is Charles Dalimar, the Big Bad from the previous game.
- Millionheir
- On the newspaper clipping announcing Phil's disappearance, one of the sections seemingly detail the credentials of the detective hired to search form him, and the pictures show the titles of the four previous games of the series (Huntsville, Prime Suspects, Ravenhearst and Madame Fate).
- There is a booth in the gaming room than features some sort of fortune telling machine with a "Madame Fate" panel on it.
- At the end of the game, Phil T. Rich decides to convert his gigantic mansion into an amusement park. The news clipping shown right after the scene shows that said amusement park was Fate's Carnival, and one of the headlines says that "Madame Fate found a home". Although, future entries of the series contradict this, as they show that Fate's Carnival is far older than that; possibly Phil T. Rich merely offered his estate as a permanent site for a carnival that used to move from town to town.
- Dire Grove
- The Detective now owns a Madame Fate bobblehead doll that sits within her car that laughs just like the real deal. This same doll would reappear in Escape from Ravenhearst and Key To Ravenhearst.
- Carved on a tree are the initials "CD+ER" in a heart, standing for « Charles Dalimar + Emma Ravenhearst ». The same carving reappears in 13th Skull, this time as a graffiti on the tavern’s crane game.
- 13th Skull
- The file entry detailing the Master Detective’s encounter with Momma Aimee states that she has not had the disquieting feeling that someone had foreseen her arrival since her introduction to Madame Fate.
- A magazine seen at the Landry’s feature Puddles the Clown, from ‘’Madame Fate’’, on its cover.
- The Malgrave Incident
- Abe Stinkin, a suspect from Prime Suspects, is seen on a newspaper.
- Shadow Lake
- A ‘’Madame Fate’’ pachinko game can be found in the Bitterford pharmacy. It even plays a remix of said game’s theme song.
- Key to Ravenhearst
- In the lighthouse, there is a piece of Memorabilia hailing from Fate's Carnival featuring Lance the Sword Swallower.
- The ship captain's diary shows that he went on a trip to Fate's Carnival and he praises Bianca, the daredevil diva, for her performance.
- Broken Hour
- Benjamin Wright, the slightly loony ghost hunter, aspires at joining the Ghost Patrol crew from Shadow Lake.
- The Master Detective finds the wallet of the deceased captain from Key to Ravenhearst, who was already mentioned to have visited Fate’s Carnival before. This is even lampshaded by the Master Detective.
"Hey - I know him! The good captain surely had a thing for visiting strange places."- One of the later puzzles in the game feature Gwendolyn and Charlotte from Key to Ravenhearst, the 13th Skull from the eponymous game and Madame Fate’s hands.
- The Black Veil
- At the beginning of the game, the Master Detective rescues a reporter that is trapped in a van about to fall in a ravine. The identity of the reporter? Alison Sterling, who was one of the students the Master Detective rescued in Dire Grove.
- In Maggie's house, there is a piece of tape with the picture of Twyla Tangle, the Contortionist from Madame Fate.
- Near the end of the game, the Master Detective experiences a near-death experience during which she has visions of Ravenhearst Manor, Dire Grove and Madame Fate.
- Incident at Pendle Tower
- Two posters, one representing Madame Fate herself and the other her trailer, appear in the locker from the construction worker’s cubicle. The Master Detective herself is surprised to see these here.
- Stickers of both a raven and Isis (Madame Fate’s cat from Fate’s Carnival) appear in Verity Wright’s car.
- When the Master Detective reaches the mirror dimension, she briefly alludes to the Shade from The Countess, hoping she would not cross paths with a similar entity there.
- A Crime in Reflection
- Due to the similar circumstances, the Master Detective regularly mentions how the case at hand reminds him of the events from The Countess.
- The tarot cards that Carol finds in the Bonus Chapter all are from the collectible tarot deck from The Harbinger, which themselves were already a nod to various characters and locations from the series.
