The following have prominent roles in all three films:
- Scorpion
- Sub-Zero I
- Johnny Cage
- Liu Kang
- Raiden
- Shang Tsung
- Sub-Zero II
- Kitana
- Shao Kahn
- Quan Chi
- Mortal Kombat (1992): Sonya Blade, Kano, Reptile, Goro
- Mortal Kombat II: Jax, Baraka, Kung Lao, Jade, Smoke, Kintaro
- Mortal Kombat 3: Cyrax, Sektor, Kabal, Kurtis Stryker, Motaro
- Mortal Kombat Mythologies: Sub-Zero: Shinnok
- Mortal Kombat 4: Jarek
- Mortal Kombat: Deadly Alliance: Drahmin, Li Mei, Nitara, Kenshi
- Mortal Kombat: Deception: Dairou, Kira, Kobra
- Mortal Kombat X: D'Vorah, Erron Black, Ferra/Torr
- Mortal Kombat: Special Forces: Tremor, No Face
