Kimble is finally able to confront the One-Armed Man and find out why the man killed Kimble's wife.
Lloyd Chandler's wife Betsy giving him an epic "The Reason You Suck" Speech when he claims that he was trying to protect her (from people gossiping about him being over at Helen's house and/or suspecting that he was the killer) by not confessing that he witnessed Helen's murder and has known all along that Richard was innocent, blasting him for both his failure to help Helen and in allowing Richard to suffer for the past 4 years, bluntly telling him that it was himself he was trying to protect because he couldn't bear for people to know he'd been such a coward and further blasting him for trying to use her as an excuse.
Gerard is able to resolve his conflict as a by-the-book cop to figure out what really happened that night, coming to terms he'd been pursuing an innocent man, and bringing justice to the entire matter.
A notable moment is when Gerard questions the One-Armed Man, who has an alibi for that time period that Gerard, having obsessed over the case for its full duration, systematically cuts down until the alternative seems to be all that's left and he explodes, "Did you kill Helen Kimble?"
The finale is one in and of itself. When it was announced the show was going to end production, the producers decided that the fans deserved a resolution to the Series Goal, but the network balked and refused to pay for it, as providing a definitive ending would have no syndication potential, and nobody cared about the fate of a fictional character anyway. So the producers paid for it, out-of-pocket, because they were convinced that it was the right thing to do. The network had so little faith in it that they aired it in the dump month of August, when hardly any new primetime television is produced, but it was a monster hit, the highest rated episode in television history for almost 15 years until "Who Shot J.R.?" Their decision was totally vindicated and (although it took the industry a while to catch on) we owe them for the entire concept of the Grand Finale in series television. To this day, the finale is fondly remembered as one of the greatest and most satisfying ever.
The pilot episode of The Remake garnered a six-minute standing ovation when shown to test audiences.
Keep in mind that Kimble is, for all his intelligence and fortitude, a doctor, while Sykes, despite the one arm, is a head of security and contract killer. And Kimble still manages to overpower him with the help of a fortunate distraction, slamming the train to a stop to throw Sykes off his feet, and then just whaling on him until he goes down.
When Kimble calls out his so-called friend Nichols for setting in motion everything bad that has happened in the movie, then capping it off by opening a can of WHUP-ASS on him.
"There's a man back there in a blue coat waving a gun and screaming. ...At a woman." Doubles as a Funny Moment in the midst of all this nail-biting tension when Gerard comes running around the corner, screaming "STOP THAT MAN!", and the officers, thanks to what Kimble has told them, do exactly what they're trained to do and restrain Gerard.
Simply put, the train is REAL. They did not use a model. The wreck, which was filmed on the Great Smokey Mountain Railroad in North Carolina, has never been cleaned up and is a highlight of eastbound Tuckasegee River excursions.
When Kimble is trapped by Gerard at the edge of the dam. His choices are to 1) get arrested yet again to sit on death row or 2) jump. He jumps.
The entire hotel sequence, from start to finish. It starts with Kimble walking into a hotel in full view of everyone to call out Nichols in public, then leads to them fighting across multiple floors, getting absolutely wrecked but refusing to go down, and ends in the laundry with Gerard revealing that he solved the case and convincing Kimble to turn himself in, just in time for Kimble to save his life with a well-placed pipe whack.
It's a little behind the scenes, but the fact that, in real life, Harrison Ford got a painful bone spur early in filming but held off getting it fixed so he'd have an authentic limp as Richard Kimble is a CMOA for him.
Gerard's Establishing Character Moment, getting the guard on the bus to admit that Kimble might have survived just minutes after his arrival.
When Kimble calls Gerard:
Kimble: Do you remember what I told you in the tunnel? Gerard: I remember it was noisy. Well, I think you said something like... "you didn't kill your wife." Kimble: Remember what you told me? Gerard: I remember you were pointing my gun at me. Kimble: You said, "I don't care." Gerard: Yeah, Richard, that's right, I don't care. I'm not trying to solve a puzzle, here. Kimble: Well, I am trying to solve a puzzle. And I just found a big piece. (puts the phone down on the desk and leaves)
Just the fact that Kimble, with presumably no police or investigative background is able to do within weeks what the detectives and his lawyer couldn't is incredibly remarkable.
Also, the fact that he puts the phone down on the desk instead of just hanging up, knowing that they must be tracing the call. He's taunting them.
He's also making sure they finish the trace and enter Sykes' home. Since Kimble broke in, the authorities can legally enter and search without a warrant.
Kimble shows how seriously he takes his Hippocratic Oath when he runs into a boy with a fractured sternum. After asking a few questions and determining the boy will die under his current treatment, Kimble changes his orders to the correct ones with no hesitation, knowing full well the attention it will draw. And he saves that boy's life.
.Kimble: I didn't kill my wife!Gerard: I don't care!