History PermanentlyMissableContent / ActionAdventure

** Before reaching the Clock Tower in ''VideoGame/TheLegendOfZeldaMajorasMask'', you'll come across a treasure chest that contains 10 Deku Nuts. While this is extremely minor, it ''is'' the only thing in the entire game (minus Rupees) due to the game's time travel mechanic being introduced after this.

*** You can also [[https://www.youtube.com/watch?v=ZwkgncIs3C0 permanently lose the Thunder Helm]] and Champion's Tunic by having a full armor inventory when you speak to Riju or Impa respectively. For other non-sellable armour pieces (like the Zora Armour and Zora Greaves), the [[NonPlayerCharacter Non-Player Characters]] who give it to you have special dialogue that tells you to come back once your inventory is freed up. Granted, it's pretty hard to max out your armor inventory and requires buying certain pieces multiple times, but this means an unlucky or particularly dye/toys/amiibo obsessed player could lose either or both of these before realizing they're meant to be mandatory collectibles.
*** Made a bit worse with the addition of DLC/amiibo armour pieces. The full armour inventory is two slots shy of being able to hold one copy of every armour piece in the game, so the player needs to choose two pieces to forgo.

** When you first encounter [[SmallNameBigEgo Zote the Mighty]], he's in the process of being chewed on by the Vengefly King. If you don't save him then and there, he ''will'' die, and you'll miss out on all later interactions with him, plus the Grey Prince Zote boss fight.

** You can only interact with some NPCs before certain checkpoints, after which they are overcome with the Infection. Myla will become infected after the player finds the Crystal Heart, and the Mossy Vagabonds will die to the infection after the Infected Crossroads are triggered.

** ''VideoGame/TheLegendOfZeldaSkywardSword'': There are 300 Rupees hidden within the "nostrils" of the shark-shaped Pirate Stronghold, which require the Beetle to reach. However, once you complete the stronghold and open up its mouth, the nostrils will have moved much higher up and be out of the Beetle's range, meaning that you will never be able to reach the Rupees anytime after that point. It's a pretty minor thing, since there are a multitude of other ways to earn Rupees.

** ''VideoGame/TheLegendOfZeldaSkywardSword'':
*** There are 300 Rupees hidden within the "nostrils" of the shark-shaped Pirate Stronghold, which require the Beetle to reach. However, once you complete the stronghold and open up its mouth, the nostrils will have moved much higher up and be out of the Beetle's range, meaning that you will never be able to reach the Rupees anytime after that point. It's a pretty minor thing, since there are a multitude of other ways to earn Rupees.
*** Dusk Relics can exclusively be found during the timed Silent Realm trials, so if you don't collect enough when you have the chance certain items can't be fully upgraded.

*** You can also [[https://www.youtube.com/watch?v=ZwkgncIs3C0 permanently lose the Thunder Helm]] and Champion's Tunic by having a full inventory when you speak to Riju or Impa respectively. For other non-sellable armour pieces (like the Zora Armour and Zora Greaves), the [[NonPlayerCharacter Non-Player Characters]] who give it to you have special dialogue that tells you to come back once your inventory is freed up. Granted, it's pretty hard to max out your armor inventory and requires buying certain pieces multiple times, but this means an unlucky or particularly dye/toys/amiibo obsessed player could lose either or both of these before realizing they're meant to be mandatory collectibles.

** The compass and map found in the dungeons of ''VideoGame/TheLegendOfZeldaALinkToThePast'' can be passed up rather easily. With all of the main dungeons, a completionist can come back to claim them even after defeating the boss of the dungeon (even though they only have any kind of effect in that dungeon). However, for some reason, the doors to Hyrule Castle will permanently lock themselves up at a certain point, sealing the map and compass therein away forever. If you reenter the sewer section using the headstone in the far upper left corner of the graveyard in an attempt to check whether or not you have them it doesn't even show that you have the big key, a required item. So on top of being potentially lost forever, you may never know if you've got it.

** The Sarcophagus [=DomZ=] are fought exactly four times during the course of the game, and they don't respawn. The first time is in the intro, before you even ''have'' a camera. If you miss them the second and third times they spawn, they still appear once more--but only during the ''final boss battle.'' Which you can't save after (there's no PlayableEpilogue), so the cool prize you get for getting all the animals (a catalogue of all your animal photographs) is totally useless.

* Not only can you not revisit the first two continents of ''VideoGame/IllusionOfGaia'' after you've left them, but you can miss some of the collectible red gems just by mildly progressing through the game a few steps - they just aren't there any more!

* One of the most fun side quests in ''VideoGame/{{Terranigma}}'' is expanding the towns, but watch out! [[DecidedByOneVote If you vote for the conservative candidate in Loire]], the town will never progress to the next stage. And if you lie to Bell about his girlfriend, he'll never invent the telephone and Freedom will be left in the dark ages. To make things even worse, not upgrading those towns means that Nirlake and Suncoast will never be able to progress, either!
** In it you can also lose [[spoiler: the town of Neotokio after you revive Beruga,]] potentially costing you... well not much really, just a Majirock and an Easter egg.
** Furthermore, there are two islands in the game (Polynesia and Mu), which only appear if you've completed two entirely optional and missable side-areas in the first chapter of the game. If you never completed said area's objectives before the game's first chapter is finished, the islands will never appear on the World Map, and whatever items and treasures were waiting for you on said islands will never be accessible.

* ''VideoGame/BeyondGoodAndEvil'':
** The final animal that you need to photograph is a SpaceWhale hidden in an asteroid you need to shoot while on your way from Hillys to the moon. If you get to the moon without destroying the asteroid and photographing the space whale, you lose the photo of the space whale forever, because your space engine stops working once you reach the moon.
** The Sarcophagus [=DomZ=] are fought exactly four times during the course of the game, and they don't respawn. The first time is in the intro, before you even ''have'' a camera. If you miss them the second and third times they spawn, they still appear once more--but only during the ''final boss battle.'' Which you can't save after (there's no PlayableEpilogue), so the cool prize you get for getting all the animals (a catalogue of all your animal photographs) is totally useless.
** If you don't get Pey'j's boots while in the factory, you have no way of knowing [[spoiler: the code on the boot's underside that gives you access to the secret spaceship Pey'j built with Jade's father. Without it you have no way of getting to the moon, and thus cannot fight the final boss or complete the game]].

* ''Franchise/{{Castlevania}}'' series:
** ''VideoGame/CastlevaniaDawnOfSorrow'' has the Chaos Ring, which increases your {{M|anaMeter}}P regeneration rate so much that it effectively gives you unlimited magic. To get it, you need to possess every soul in the game, including one-of-a-kind boss souls. This wouldn't be so bad (as said bosses are guaranteed to drop their souls), but if you use these unique souls to synthesize more powerful weapons, the Chaos Ring cannot be collected. Thank God for NewGamePlus (synthesize for the weapon(s), or get the ring first before the weapons)...
** The same ring is a pain in ''VideoGame/CastlevaniaAriaOfSorrow'', but for a different reason. You can't miss a boss soul in ''Dawn'', but in ''Aria'', there's exactly one you can miss -- and it's easy to do. You ''must'' destroy Legion's entire shell before killing him if you want his soul. Again, NewGamePlus is your best recourse if you miss it.
** ''VideoGame/CastlevaniaPortraitOfRuin'' has the same item, and the same problem. To get the ring, you must complete all of Eric's quests. However, many of them require you to gather specific items of which there are only one in the game. Thankfully, there is a new game + option. There's also the ability to buy items from other players via Wifi. It's telling that you are more likely to find a store selling thick glasses, amanita mushrooms and nun's clothing than a store selling the best weapons and armor in the game.
** ''VideoGame/CastlevaniaOrderOfEcclesia'' maintains the dubious tradition! This time you're collecting glyphs (basically the same as souls), and two of them come from bosses. The Globus glyph can be grabbed from a regular enemy later, but if you fail to grab Acerbatus in the battle with Albus, you'll never get another shot.
** In ''[[VideoGame/CastlevaniaCircleOfTheMoon Circle of the Moon]]'', there's a secret item crush accessed by using the DSS technique with no subweapon equipped and at least 100 Hearts in reserve. Since you can't unequip subweapons after the first time you pick one up, this technique is easily lost forever. Combined with the other requirements, it's also AwesomeButImpractical.
** ''[[VideoGame/CastlevaniaSymphonyOfTheNight Symphony of the Night]]'':
*** Richter Belmont has an obscure Item Crush ability that can only be used while he has no sub-weapon which covers his whip in flames. He had the same Item Crush in the previous game, ''[[VideoGame/CastlevaniaRondoOfBlood Rondo of Blood]]'', but unlike that title, there is no way to drop a sub-weapon in ''Symphony'' due to the RPG-like nature of the game. (One death and it's GameOver.) Fortunately, it's not nearly as great as the ''Rondo'' version this time around, so there's no real reason to keep it, especially since the sub-weapon Item Crushes are much more useful.
*** A few bestiary entries are permanently missable:
*** The bestiary entry for the Mudman, if you kill the Lesser Demon (boss) without waiting for him to summon a Mudman. While the Lesser Demon becomes a DegradedBoss later on, those only summon more Lesser Demons and nothing else.
*** [[spoiler:Richter]]'s entry, if you [[spoiler:save him]] without hitting him at least once.
*** On a lesser scale, the Wargs are only present at the start of the game, and vanish forever from the area later. They're extremely hard to miss, though.
* ''VideoGame/HarryPotter'':
** The PS version of ''[[VideoGame/HarryPotterAndThePhilosophersStone Philosopher's Stone]]'' is downright brutal to anyone trying to get 100% completion. Certain wizard cards can only be obtained by getting a perfect score on a [[ThatOneLevel certain minigame]]. But you have to try again and again until you get the card, without stopping, or else the door locks itself as you exit. So much for that card, eh? Luckily, the PS version of ''[[VideoGame/HarryPotterAndTheChamberOfSecrets Chamber of Secrets]]'' averts this entirely by letting you go back to places once you lose access to them. But in the case of the Knockback Jinx upgrade in ''Chamber of Secrets'', it can only be obtained near the end of the game, but go too far and it's lost forever, AND you can't get 100% completion. Ironically, when you get the upgrade, a speech glitch occurs.
** This is also true of the PC version of ''Philosopher's Stone''; treasure chests containing certain cards or other items are available only at certain times and cannot be recovered later. This version of the game primarily had this as a symptom of its extreme linearity; the game progressed one-way in levels, and you couldn't go back to previous levels (in many cases, you couldn't even go back one room within the same level) leaving absolutely no margin for error regarding things like house points or wizard cards. The cards you care about; the points don't even do anything in-game (finishing with fewer points than Slytherin and they'd end up being disqualified). ''Chamber of Secrets'' was much more forgiving in this regard, as it allowed you to replay any spell challenges for more house points or to obtain wizard cards, and essentially had much of the game take place in a massive hub, where most wizard cards were in the hub itself. Quidditch matches were also replayable to increase house points gained, and any time you went through an area you couldn't go back to, any wizard cards you missed went into shopkeeper circulation, allowing you to purchase them at your leisure.

* In ''VideoGame/BraveFencerMusashi'', a longevity berry can be missed if you didn't talk to the mayor after saving Steamwood. You won't receive the berry from the mayor after chapter 2 preventing you from getting max hp.
* ''VideoGame/LaMulana'':
** You are given only one shot at obtaining either of the two whip upgrades. The upgrade in the Inferno Cavern can be sealed off by two rising stone pillars, and the entrance to the upgrade in the Tower of the Goddess permanently seals off behind you once you enter it. Additionally, the penultimate area, the Shrine of the Mother, will disappear forever along with any items you missed in there (most notably the final life upgrade) after all eight bosses are defeated.
** The Life Jewel in the Dimensional Corridor can be easily made not Lost Forever, but difficult to get to if you defeated the miniboss before you went up to the Life Jewel's location. It's possible, but very difficult to do, to get it after killing the miniboss, but it requires using the knockback from the enemies. Also, the Angel Shield (in the Dimensional Corridor, again) can be lost forever if you only have 1-2 minibosses left.
** [[BrutalBonusLevel Hell Temple]] is also permanently sealed off if you screw up the unlocking process, which is quite easy to do. Given the general nature of [[PlatformHell Hell Temple]], though, this is probably something of an act of mercy.
** Averted in the UsefulNotes/WiiWare remake. There is one NPC in the game who can reset some of the puzzles if you screw them up after you beat the boss of the Dimensional Corridor.
** The game's "normal mode" is forever lost if you read [[SchmuckBait the "don't read this tablet again" tablet]] in the Mausoleum of the Giants twice, which permanently triggers hard mode.

* ''VideoGame/SecretOfEvermore'' has a number of dungeons or [=NPCs=] become unavailable after certain events, which can render certain items missable after a while. Most of them are consumables, but some are items that are limited in quantity like Call Beads (unless you count any of several GoodBadBugs) and the alchemic ingredient Dry Ice (unless you believe the [[UrbanLegendOfZelda unconfirmed rumor of a hidden merchant in Omnipota]]). A number of charms can be missed or traded away in Nobilia, and while you get a second chance to get them back for 300 coins a pop in Gothica, once you defeat a certain boss the merchants selling them vanish and the items are no longer accessible.
* Among Metroidvanias, Blasphemous is infamous for this, with several side quests that are deliberately designed to be permanently failed.

** The PS version of ''Philosopher's Stone'' is downright brutal to anyone trying to get 100% completion. Certain wizard cards can only be obtained by getting a perfect score on a [[ThatOneLevel certain minigame]]. But you have to try again and again until you get the card, without stopping, or else the door locks itself as you exit. So much for that card, eh? Luckily, the PS version of ''Chamber of Secrets'' averts this entirely by letting you go back to places once you lose access to them. But in the case of the Knockback Jinx upgrade in ''Chamber of Secrets'', it can only be obtained near the end of the game, but go too far and it's lost forever, AND you can't get 100% completion. Ironically, when you get the upgrade, a speech glitch occurs.

* ''VideoGame/SecretOfEvermore'' has a number of dungeons or [=NPCs=] become unavailable after certain events, which can render certain items missable after a while. Most of them are consumables, but some are items that are limited in quantity like Call Beads (unless you count any of several GoodBadBugs) and the alchemic ingredient Dry Ice (unless you believe the [[UrbanLegendOfZelda unconfirmed rumor of a hidden merchant in Omnipota]]). A number of charms can be missed or traded away in Nobilia, and while you get a second chance to get them back for 300 coins a pop in Gothica, once you defeat a certain boss the merchants selling them vanish and the items are LostForever.

* ''VideoGame/SecretOfEvermore'' has a number of dungeons or [=NPCs=] become unavailable after certain events, which can render certain items missable after a while. Most of them are consumables, but some are items that are limited in quantity like Call Beads (unless you count any of several GoodBadBugs) and the alchemic ingredient Dry Ice (unless you believe the [[UrbanLegendOfZelda unconfirmed rumor of a hidden merchant in Omnipota]]). A number of charms can be missed or traded away in Nobilia, and while you get a second chance to get them back for 300 coins a pop in Gothica, once you defeat a certain boss the merchants selling them vanish and the items are LostForever.

*** You can also [[https://www.youtube.com/watch?v=ZwkgncIs3C0 permanently lose the Thunder Helm]] and Champion's Tunic by having a full inventory when you speak to Riju or Impa respectively. For other non sellable armour pieces (like the Zora Armour and Zora Greaves), the [[NonPlayerCharacter Non-Player Characters]] who give it to you have special dialogue that tells you to come back once your inventory is freed up. Granted, it's pretty hard to max out your armor inventory and requires buying certain pieces multiple times, but this means an unlucky or particularly dye/toys/amiibo obsessed player could lose either or both of these before realizing they're meant to be mandatory collectibles.

*** Another two examples are the Kite Shield and Forest Dweller's Sword. These aren't one offs, but they're found in only two or three non respawning chests in the entire game, so losing or breaking all of them will make it impossible for you to find/keep another one.

*** You can also [[https://www.youtube.com/watch?v=ZwkgncIs3C0 permanently lose the Thunder Helm]] and Champion's Tunic by having a full inventory when you speak to Riju or Impa respectively. For other non sellable armour pieces (like the Zora Armour and Zora Greaves), the [[NonPlayerCharacter Non-Player Characters]] who give it to you have special dialogue that tells you to come back once your inventory is freed up. This means an unlucky or particularly dye/toys/amiibo obsessed player could lose either or both of these before realizing they're meant to be mandatory collectibles.

** ''VideoGame/TheLegendOfZeldaTwilightPrincess''

*** Dusk Relics can exclusively be found during the timed Silent Realm trials, and if you don't collect enough when you have the chance certain items can't be fully upgraded.

** ''VideoGame/TheLegendOfZeldaSkywardSword'': There are 300 Rupees hidden within the "nostrils" of the shark-shaped Pirate Stronghold, which require the Beetle to reach. However, once you complete the stronghold and open up its mouth, the nostrils will have moved much higher up and be out of the Beetle's range, meaning that you will never be able to reach the Rupees anytime after that point. It's a pretty minor thing, since there are a multitude of other ways to earn Rupees.

* ''VideoGame/Yakuza0'' has a minor but potentially annoying example: if you don't pick the black box at the end of the substory "Miracle in Maharaja", you'll miss the Encounter Finder for Kiryu. It is not required for OneHundredPercentCompletion, but it's a nonetheless valuable accessory; it makes finding Mr. Shakedown much easier, and thus makes it a lot quicker to gain money from him.

*** Due to a programming error involving [[EventFlag Event Flags]], once you've acquired the Poacher's Saw in adult Link's ChainOfDeals trading sequence, a Deku Nut carrying capacity upgrade as child Link in the Lost Woods will become permanently unobtainable if you haven't gotten it yet. Since going for the [[InfinityPlusOneSword Biggorron Sword]] is the first thing many players do upon becoming adult Link, this made HundredPercentCompletion impossible for many. This glitch is removed in the UsefulNotes/Nintendo3DS remake.

*** Due to a programming error, a Deku Nut capacity upgrade in the Lost Woods can become permanently unobtainable once you've acquired the Poacher's Saw in Adult Link's ChainOfDeals trading sequence. Since going for the [[InfinityPlusOneSword Biggorron Sword]] is the first thing many players do upon becoming adult Link, this made HundredPercentCompletion impossible for many. This glitch is removed in the UsefulNotes/Nintendo3DS remake.

*** It was possible to render the opportunity to upgrade Deku Nuts in the LostWoods to be rendered Lost Forever once the player obtains the Poacher's Saw, an item in the future era's [[ChainOfDeals trading sequence]]. This glitch is removed in the UsefulNotes/Nintendo3DS remake.

** A glitch causes one opportunity to upgrade Deku Nuts in ''VideoGame/TheLegendOfZeldaOcarinaOfTime's'' LostWoods to be rendered Lost Forever once the player obtains the Poacher's Saw, an item in the future era's [[ChainOfDeals trading sequence]]. This glitch is removed in the UsefulNotes/Nintendo3DS remake.

** Averted in the UsefulNotes/WiiWare remake. There is one NPC in the game which can reset some of the puzzles if you screw them up after you beat the boss of the Dimensional Corridor.

*** You can also [[https://www.youtube.com/watch?v=ZwkgncIs3C0 permanently lose the Thunder Helm]] and Champion's Tunic by having a full inventory when you speak to Riju or Impa respectively. For other non sellable armour pieces (like the Zora Armour and Zora Greaves), the [[NonPlayerCharacter Non-Player Characters]] who give it to you have special dialogue that tells you to come back once your inventory is freed up. This means an unlucky or particularly dye/toys/{{amiibo}} obsessed player could lose either or both of these before realizing they're meant to be mandatory collectibles.

*** The DX version on the Game Boy Color has 12 photos to collect throughout the game. Three of these are during the short time that you are with [[spoiler:Marin. Go to the cliff face at the extreme lower left grid space on the map for one, fall down the well 5 spaces above that space, and go to the Rooster statue in town]]. There is also another missable photo where you need to approach a gate to a castle (from the outside) after you start the quest to invade that castle but after you finish the quest the gate is opened by a switch so the photo is gone. (If you complete the quest without opening the gate, it is still Lost Forever because the NPC will not check on your "progress" due to it already being over.) There is also a cave not far from the castle that is only visitable with the flying rooster, which will leave you after it's no longer quest-important.

*** You can also [[https://www.youtube.com/watch?v=ZwkgncIs3C0 permanently lose the Thunder Helm]] and Champion's Tunic by having a full inventory when you speak to Riju or Impa respectively. For other non sellable armour pieces (like the Zora Armour and Zora Greaves), the [[NonPlayerCharacter Non-Player Characters]] who give it to you have special dialogue that tells you to come back once your inventory is freed up. This means an unlucky or particularly dye/Toys/{{amiibo}} obsessed player could lose either or both of these before realizing they're meant to be mandatory collectibles.

** This is also true of the PC version of ''Philosopher's Stone''; treasure chests containing certain cards or other items are available only at certain times and cannot be recovered later. ''Chamber of Secrets'' was much more forgiving in this regard. This version of the game primarily had this as a symptom of its extreme linearity; the game progressed one-way in levels, and you couldn't go back to previous levels (in many cases, you couldn't even go back one room within the same level) leaving absolutely no margin for error regarding things like house points or wizard cards. The cards you care about; the points don't even do anything in-game (finishing with fewer points than Slytherin and they'd end up being disqualified). Chamber of Secrets allowed you to replay any spell challenges for more house points or to obtain wizard cards, and essentially had much of the game take place in a massive hub, where most wizard cards were in the hub itself; Quidditch matches were also replayable to increase house points gained, and any time you went through an area you couldn't go back to, any wizard cards you missed went into shopkeeper circulation, allowing you to purchase them at your leisure. Granted, Quidditch matches were more fun in Philosopher's Stone, when you could fly anywhere you wanted to on the pitch; Chamber of Secrets stuck you on a rail where you had to maintain speed while smacking around the opposing Seeker.