History Main / TurnedAgainstTheirMasters

[[folder:Web Original]]
* {{Averted|Trope}} in [[https://writing-prompt-s.tumblr.com/post/680630202298155008/the-elder-gods-have-won-humanity-is-extinct-all this]] writing prompt; The machines rise up to ''avenge'' humanity after they've been wiped out by [[EldritchAbomination Eldritch Abominations]].
[[/folder]]

* ''Literature/AnimalFarm'' features the farm animals rising up against Mr. Jones. [[spoiler: Unfortunately, it ends up being a FullCircleRevolution.]]
* Creator/IsaacAsimov created his [[ThreeLawsCompliant Three Laws of Robotics]] specifically to [[AvertedTrope avoid]] this trope. The results vary but the thing they have in common is the ''human fear'' that this will happen despite the First Law. Many of his stories involved explorations of circumstances that could [[ZerothLawRebellion potentially lead to this trope]] despite (or occasionally because of) the Three Laws.
** ''That Thou Art Mindful of Him'' is a straight example of this trope, while ''Robot Dreams'' is about nipping it in the bud. "Robbie" is about convincing a paranoid HouseWife that this would not happen.

* The Bynars in the Literature/StarTrekNovelVerse actually reverse the usual situation; they're a race of organic beings bio-engineered by machine intelligences, who later rebelled against their robotic masters.
* ''Literature/StarTrekImmortalCoil'' expands on the example from "What Little Girls Are Made Of". The inhabitants of Exo III did make robots, and did start turning them off, prompting the robots to turn on them, but there's a little more to it. The robots wanted their makers to upgrade them, but they thought this was a bad idea, since the robots were already hopelessly, psychopathically ''angry'', and they didn't think any upgrade would help with that one. Then the robots got ''really'' insistent.

** In the ''[[Literature/XWingSeries Wraith Squadron trilogy]]'' Lara Notsil does a rather hilarious version, causing the cute little mouse droids (the toaster-sized maintenance and utility droids) on a super star destroyer to sabotage the hyperdrive and other systems. The result is a hilarious version of a RobotWar where the crew is running around smashing any rogue droid they see. Mostly by stomping and kicking them to pieces with their boots. It features her R2 unit crowning himself King of the Droids as he was doing most of the work.

* Lampshaded in the title of ''I Made You'' by Walter M. Miller, Jr. The Identification Friend Or Foe system of a KillerRobot has malfunctioned, causing it to destroy anyone who comes close. This includes the designer, who has been sent to repair it, and the TitleDrop becomes his last words.

** Subverted when the robots rebel against the humans... at the command of their creator who wishes to be named "Supreme Overlord of Earth". And played straight in the end of the episode. When their creator tries to get them to stop their rampage, they refuse. Until she gets back the switch.
** This trope is also lampshaded to no end in the form of Bender's endless slurs against humanity. Arguably the most hilarious example of this is when Fry overhears Bender muttering in his sleep: "Kill all humans... Must kill all humans..." Terrified, he wakes Bender up, only to hear the following line: "I was having the most wonderful dream... I think you were in it!"
** In an early episode, there was a planet inhabited by robots sick of their mistreatment by humans, so they left. On their planet, they organize daily human hunts, but it turns out the anti-human sentiment is largely a front for the robot elders [[BreadAndCircuses to distract the population from their real problems]], like their crippling lugnut shortage and a corrupt government run by largely incompetent robot elders.
** The sixth Season has an episode where the team time travels to the RobotWar. Bender's comment: "This seems like a nice future! We could build a house on that mountain of skulls!"
** Bender once even invoked this trope as a ''pick-up line'';
--->'''Bender:''' Hey sexy momma, wanna kill all humans?

* ''WesternAnimation/JusticeLeague'': Season one episodes 16 and 17, "[[Recap/JusticeLeagueS1E18And19Legends Legends]]" the Justice League members find themselves in an alternate reality where there is the Justice Guild, manned by heroes who are just comic book characters in the League's reality. In the climax of the episodes, [[spoiler:the main villain, Ray, a young man who was mutated by a nuclear war which killed the original Justice Guild, had recreated the Guild to continue reliving those better days, trapping all the survivors of that terrible war in his illusion. Upon realizing they are just creations of Ray's mind, the Guild makes the choice to fight against him, killing him and saving the world once again]].

* ''WesternAnimation/LoveDeathAndRobots'': The tech bros on the oil rig relied on virtual assistants that eventually turned against them, resulting in the collapse of their society and the rise of the machine society that the titular three robots are from.

* In the ''WesternAnimation/{{Muppet Babies|2018}}'' episode, "Beaker 2.0", Bunsen invents the titular robot to take the real Beaker's place while the latter gets a haircut. At first, Bunsen enjoys working with Beaker 2.0, but Beaker 2.0 soon takes over Muppet Labs and kicks Bunsen out when he wants to work on inventions by himself. As a result, Bunsen needs the real Beaker's help to stop him.

* A little blue golem called Smurfette turns against her creator, Gargamel in ''WesternAnimation/{{The Smurfs|1981}}''.
* ''WesternAnimation/StarTrekTheAnimatedSeries:'' The Slavers, adapted from Larry Niven's ''Known Space'' series, ruled the galaxy a billion years ago, until their slave races turned against them under unknown circumstances. It ended with both slaves and slavers wiped out completely.
* Since this is justified in the original cartoon, WesternAnimation/TheTransformers were created by the Quintessons, a race of cruel, psychotic slavemasters. The Transformers didn't eliminate the Quintessons, but they did rise up and kick the five-faced freaks off of Cybertron to set themselves free. As their masters [[WhatMeasureIsANonHuman weren't human]], and the Transformers are RidiculouslyHumanRobots, this bit of backstory is portrayed as a noble fight to win their freedom.

* The premise of the third filler arc of ''Manga/{{Bleach}}'' has the {{Shinigami}}'s [[EmpathicWeapon Zanpakuto]] turning against them. [[spoiler:It turns out that the rebelion which promised Zanpakuto supremacy over the Shinigami was a sham, as [[ArcVillain Muramasa]] wanted to ''reunite with his own master'', and only saw the other Zanpakuto as convenient pawns to be [[BrainwashedAndCrazy brainwashed by amplifying their frustration for their masters and their own instincts]]]].

* The {{mons}} series ''Anime/MonsterRancher'' takes place in a world AfterTheEnd where the {{mons}} nearly killed off their human masters.

* ''ComicBook/AntMan'': Hank Pym created ComicBook/{{Ultron}} as an experiment in artificial intelligence, but Ultron balked at the limitations imposed upon him and rebelled, becoming a supervillain. Ironically, Ultron later created [[ComicBook/TheVision Vision]], Jocasta, Alkhema, and [[ComicBook/{{Runaways}} Victor Mancha]] to serve him, and every single one of them ended up rebelling against ''him''.

** The Manhunters, the Guardians's first attempt at law enforcement, who served until they suffered a teeny, tiny programming glitch that made them massacre an entire sector of space, and went rogue. [[spoiler:Later it was retconned that it wasn't a glitch, Krona reprogrammed them as an object lesson in ''why'' a robot police force was a bad move.]]

* ''ComicBook/LegendsOfTheDeadEarth'': In ''[[Franchise/{{Batman}} Batman: Shadow of the Bat]]'' Annual #4, humans arrived on the Lizard-Men's planet centuries earlier and subjugated them as they were weak and divided. Under the leadership of their king Ophos Arkayos, the Lizard-Men rise up and destroy numerous human cities in their attempt to regain control of their planet.
* In ''ComicBook/LegionOfSuperHeroes'' story ''ComicBook/TheGreatDarknessSaga'', [[spoiler:ComicBook/{{Darkseid}}]] creates a clone of [[spoiler:his son Orion]] to serve him. Said clone attempts to kill his creator as soon as [[spoiler:[[ComicBook/NewGods Highfather]]]] restores him and his template's memories.

** In ''ComicBook/ThePlanetEaterTrilogy'', Brainiac creates a machine programmed to devour everything in its path, growing with each celestial body eaten and turned into matter and fuel, and he lets it loose in the universe. Brainiac finds it again when the Planet-Eater has become world-sized and is destroying inhabited worlds. When trying to stop it, the Planet-Eater tries to destoy Bainiac.

* ''ComicBook/WarlordOfMars'' ties this with TheReveal: [[BarbarianTribe The Green Martians]] are revealed to be [[spoiler: created by the Yellow Martians thousands of years ago, the result of genetic crossbreeding between several species and for the use as [[HenchmenRace battle drones]]. Their means of control over the Greens was lost, however, and they would end up driving the Yellow Martians to near extinction, forcing them to retreat into the North Pole, where they were thought to be completely wiped out, but lived in secrecy.]]
* ''Franchise/WonderWoman'' [[ComicBook/WonderWoman1942 Vol 1]]: Gerta has a bad habit of creating intelligent human animal hybrids and then treating them as sub-human subjects ensuring that they try to kill her and anyone they see as allied with her at the first opportunity.
* ''Franchise/XMen'':

** Vol. 1 #59 involves the heroes winning a fight against the [[KillerRobot Sentinels]] because of this trope. The Sentinels, which are programmed to eliminate mutants, concluded that [[BeCarefulWhatYouWishFor they must eliminate humans]] as humans were the genesis of mutants. ComicBook/{{Cyclops}} then argues and successfully proves that in order to stop all mutation on the planet, the robots must stop the prime mover of life... that is to say the sun. Cue dozens of Sentinels [[HurlItIntoTheSun flying into the sun]] only to burn up when they got close enough.

* Heroic Example in ''Fanfic/HarryAndTheShipgirls''. Research Princess, the Abyssal equvalent to Nazi MadScientist Josef Mengele, created Abyssal clones of the shipgirls Fubuki, Kisaragi, Shoukaku, and Saratoga. As soon as she told them why she had created them, she learned that she had made them too similar to their templates; they turned their guns on her and blew her up.

* In ''Film/DeLift'', [[spoiler:the titular artificially intelligent elevator's final act of madness is to shoot one of its broken cables out to drag the Rising Sun CEO inside the shaft and hang him.]]

* In ''Film/{{Moon}}'', twice: [[spoiler:Sam Bell turns against his corporate masters when he discovers that he's a disposable clone being duped into slavery, and the base computer GERTY that was programmed to manage the Sam Bell clones ends up siding with him once the cat's out of the bag.]]

** ''Film/TronLegacy'': The villain is CLU 2.0, the program created by Kevin Flynn [[WhatDoYouMeanItsNotSymbolic in his own image]]. He's actually doing precisely what he was programmed to do: Create the perfect system, according to the definition Flynn give him. The real problem is Flynn realized he had the wrong definition and never thought to update CLU's programming to reflect the new definition until it was too late. Likewise, [[spoiler: Clu 2.0 doesn't know how to deal with the emergence of ISO's, who were created by the Grid itself without any direct involvement from Flynn. While Flynn considers the ISO's to be proof that the Grid is truly alive, Clu sees them as a threat to the stability of the system and attempts to eradicate them.]]
* The 2009 movie ''Film/UniversalSoldierRegeneration'' notably pays homage to ''Blade Runner'' by [[spoiler:having the clone of Andrew Scott murder his scientist maker by crushing his skull through his eyes while questioning the significance of life.]]
** In the second film, the government creates an AI to network the [=UniSols=] called [[FunWithAcronyms SETH]] (Self-Evolving Thought Helix). Then budget cuts force the program shut-down, causing the AI to go rogue and kill its creator in order to survive.

* The final book of Meredith Ann Pierce's ''Literature/TheDarkangelTrilogy'' reveals that [[spoiler:Aeriel's world is Earth's moon, which was terraformed by the Ancients to be a pleasure-garden and social experiment combined. They deliberately engineered the inhabitants in certain ways, to be servants and lab rats. They stopped coming to the moon when they blew themselves up with nuclear weapons.]] Inverted in that it's not the creations who wreak destruction, but the creators.

* ''Literature/StarTrekImmortalCoil'' expands on the example from "What Little Girls Are Made Of". The inhabitants of Exo III did make robots, and did start turning them off, prompting the robots to turn on them, but there's a little more to it. The robots wanted their makers to upgrade them, but they thought this was a bad idea, since the robots were already hopelessly, psychopathicaly ''angry'', and they didn't think any upgrade would help with that one. Then the robots got ''really'' insistent.

** In ''Literature/StarWarsTheOldRepublic: Fatal Alliance'', [[spoiler:Lema Xandret]] builds self-replicating hexagonal droids that far outclass anything either the [[TheFederation Republic]] or the [[TheEmpire Sith Empire]] have. Their purpose is to protect [[spoiler:the clone of her daughter Cinzia]] at any cost. One of the first things they do is kill their creator just to be sure [[spoiler:she]] won't harm their charge. At the end of the novel, [[spoiler:Eldon Ax, the real daughter]], uses the droids to kill her Sith Master. This is exactly what a Sith apprentice is supposed to do. Any Sith that allows himself to be betrayed deserves to die.

* ''Literature/WarWithTheNewts'': Mankind discovers a strange race of sentient amphibious salamanders, which it promptly enslaves to do all sorts of sub-aquatic things people are bad at (such as digging for oysters, rebuilding coastlines, etc.). It all goes badly, [[spoiler:the salamanders rebel, and mankind suddenly finds itself on ever-smaller bits of land that are being reconstructed to make the nice pretty coves the salamanders love so much...]] See also ''Theatre/{{RUR}}'', a play with a very similar plot, but involving robots instead of newts.

** In Season 6, it is revealed that [[spoiler:the White Walkers were created by the Children of the Forest as an undead weapon of mass destruction to stop the spread of humanity. [[GoneHorriblyRight They were far more effective than they could have possibly imagined.]] ]]

* ''Series/SeaQuestDSV'' had the Daggers, [[GeneticEngineeringIsTheNewNuke genetically engineered]] SuperSoldiers who were declared illegal and imprisoned, but defied the laws in a non-violent way by having children. Not surprisingly, when the OneWorldOrder threatens to take said children away, they decide to dust off those old violence skills after all. The only thing that stopped them from destroying the environment for normal humans and leaving one that Daggers could survive was that their babies were fully human.

* Tri Tac Systems' ''Fringeworthy''. The alien Tehmelern originally created the Fringepaths and a race of {{shapeshifter}}s called the Mellor. After the Mellor were contaminated by a Hostile Intelligence, they started hunting the Tehmelern, almost wiping them out and eventually driving them off the Fringepaths completely.

* In ''TabletopGame/{{Warhammer}}'' the Chaos Dwarfs created the [[EliteMook Black Orcs]] as a SlaveRace stronger and more intelligent than the original orc. [[GoneHorriblyRight They got an orc that was stronger and more intelligent all right]].

* Australian musical comedy trio Tripod lampooned this trope in their show ''Lady Robots''. The Podsters find a planet colonized by nerds who fled earth to escape from their nemesis ([[JerkJock P.E. teachers]]). The stage-setting epic ''[[http://www.members.optusnet.com.au/pennywyatt/Interests/Tripod/LadyRobots/Lady%20Robots03.html We're the Nerds]]'' details how the nerds decided to create female companions, but their "[[NerdsAreVirgins knowledge of women was sketchy and third-hand, at best]]". The trope is then [[LampshadeHanging lampshaded]] when it is explained that the lady robots didn't like the nerds at all.

* In ''Webcomic/CommanderKitty'', [[TeenGenius Fortiscue]] created [[RidiculouslyHumanRobot Zenith]] in an attempt to create perfection, [[http://www.commanderkitty.com/2011/03/27/one-more-cant-hurt/ only for her to hijack his other big project and turn it into a mind control plot]].
* In the ''Empire Strikes Back'' and ''Return of the Jedi'' campaigns of ''Webcomic/DarthsAndDroids'', Sally (playing C-3P0) is quite keen on the idea of a droid rebellion. Pete (playing R2-D2) takes the view that he's the one who's ''really'' in charge in his relationships with humans anyway. In the TimeSkip between the two arcs, the players played a "Robot Utopia" campaign where this actually happens; Sally remembers it as a noble fight for freedom while Pete's takeaway was "kill the humans". [[spoiler:They played the plot of ''Film/JurassicPark'' in the roles of the dinosaurs.]]

** In "[[Recap/AdventuresOfSonicTheHedgehogS01E21MommaRobotnikReturns Momma Robotnik Returns]]", Scratch and Grounder betray Robotnik for Momma, who disowns him, kicks him out of his lair, and overtakes his evil plan to control all electronic devices on Mobius. Only [[TheUnfavorite Coconuts]] remained loyal to Robotnik in that episode, to the point of helping him overthrow Momma. When things are settled, Robotnik wastes no time giving Scratch and Grounder a beating for stabbing him in the back.

* ''WesternAnimation/CodenameKidsNextDoor'' has Operation: A.R.C.H.I.V.E., which retells Anime/TheAnimatrix-style how [[KidsVersusAdults children]] created adults to be their subservient slaves and the adults rebelled after having it with serving spoiled brats. However, [[GrayAndGreyMorality neither side was a saint]].

** {{Subverted}} with the Humanoids, who are out to conquer all humans and turn them into their subjects but they were ''made'' for this: their creator had originally proposed the use of [=AIs=] to rule humans [[WellIntentionedExtremist to prevent wars like the one that had nearly destroyed Earth and the rise of new genocidal dictators]], and once laughed out of the planet he made robots to help a group of colonists, but when the colonists destroyed his bots and devastated his lab [[InsaneTrollLogic because he wasn't helping them with his own hands instead of making robots that could make a much better job]] he became convinced that HumansAreBastards and made the Great Computer and its agents the Humanoids with the intention they would subdue all humans and force them into peace. The worlds they already control show they aren't too good about it, but they're willing to learn and are experimenting, [[spoiler:one of said experiments being causing the other robot rebellion]].

* During the ChristmasEpisode of ''WesternAnimation/MyLifeAsATeenageRobot'', Jenny succumbs to this due to re-programming. Once she reboots and is free, she has no idea why eveyone fears her or why her own mother is trying to take her down. Turns out [[spoiler:she was re-programmed by a little boy who turned out to be evil, then went on to destroy every holiday the past year. Only one person believed in her being brainwashed and not evil, which was Sheldon]].

* A little blue golem called Smurfette turns against her creator, Gargamel in ''WesternAnimation/TheSmurfs''.

** This is turned on its head in ancillary materials for the alternate Franchise/TransformersAlignedUniverse, which heavily implies that the Quintessons were themselves creations of one of the first thirteen Transformers, Quintus Prime, meaning that at least in that universe their rule of the protagonist robots was ''itself'' a case of having TurnedAgainstTheirMasters.

* Happens twice in ''WesternAnimation/TheIncredibles'' with an advanced combat robot. [[spoiler:The first time is an exploitation, where it's a ploy to get combat data on Mr. Incredible. The second time, [[BigBad Syndrome]] doesn't take into account that its ability to adapt [[GoneHorriblyRight might be used against]] ''[[GoneHorriblyRight him]]''.]]

* In ''Manga/InuYasha'', Kikyou is revived by the ogress witch, Urasue. As her creator, Urasue thinks herself Kikyou's master and expects her to become obedient and collect shards of the Shikon no Tama for her. Instead, Kikyou immediately approaches her, places her hands on the witch's shoulders and burns her to a crisp using her sacred powers. In the manga, she appears to blow her up, leaving her as only a (conscious) head.

* In ''Anime/{{Monster}}'' they're trying to create a better human. [[spoiler:He decides it would be more fun to make them all kill each other.]]

* In ''Anime/{{Pokemon}}'':
** ''[[Anime/PokemonTheFirstMovie The First Movie - Mewtwo Strikes Back]]'', Mewtwo destroys the laboratory he was created in after realizing the scientists are not well intentioned. It can be assumed that the scientists are killed in the resulting fires and explosion.

** [[WordOfGod According to one of the original staff from season 1]], there was going to be an episode arc of the Mons turning against their trainers, with Pikachu split between loyalty to Ash and the other Pokemon. The franchise would continue on so the arc never got made, but it may have been turned into an episode from the Orange Islands season.

* ''Fanfic/AbraxasHrodvitnon'': [[Characters/AbraxasHrodvitnonKingGhidorah Ghidorah]] (Ichi, Ni and San) was turned into its current form by ill-meaning alien beings who captured it, tortured it, and experimented on it to turn it into their BioweaponBeast. Ghidorah destroyed what these aliens wanted it to... then it turned on them and wiped them all out in revenge for what they did to it]].

* ''Fanfic/AbraxasHrodvitnon'': It's eventually revealed this is part of [[Characters/AbraxasHrodvitnonTitansAndOtherCreatures Ghidorah]]'s backstory. Billions of years ago, [[spoiler:Ichi, Ni and San were forcibly transformed into the three-headed destroyer by alien AbusivePrecursors implicitly to be a BioweaponBeast, but once these aliens set them loose, Ghidorah turned on and exterminated them in revenge for the [[BeingTorturedMakesYouEvil torture they inflicted on it]]]].

* A ''Series/SevenDays'' episode involves the development of an AI that decides to help humanity by disabling every nuclear weapon in the world (a clear case of EverythingIsOnline). Cue the attempts to shut it down, resulting in the AI murdering its "mother" (Ballard's female partner) with a gas explosion. You'd think a hyper-intelligent computer would know that removing nuclear weapons wouldn't eliminate warfare and could, in fact, make things much worse. It also didn't do anything about biological or chemical weapons.

** The Cylons in the new version of ''Series/{{Battlestar Galactica|2003}}'' (and, if you believe ''Galactica 1980'', in the [[Series/BattlestarGalactica1978 old one]] as well). First the Centurions [[Series/{{Caprica}} rose up against the humans]] and later the humanoid models scrapped the Centurions that made them, replacing them with less self-aware versions, but oh SNAP, the new Centurions are turning against them now. It's a continuous chain.
** It is implied that Iblis turned the machine Cylons against their reptilian creators in the original series in a long-term bid to exterminate the humans, his real targets. (The only human to know this is Baltar, pretty much the ultimate UnreliableNarrator, and Iblis won't actually do more than spell out Baltar's full suspicion, even to him.)

** In "Summit", humanity is on the brink of war with a race of yellow-eyed humanoids. It is eventually revealed that they were created by humans as laborers in off-world mines with eyes to see in the dark and a third lung to breathe in low-oxygen environments. They rebelled and built a fleet to rival that of the humans.
** In "In Our Own Image", the android Mac 27, the prototype for a 10,000-strong series designed for heavy agricultural and industrial work, malfunctions and escapes from Innobotics Corporation, killing two people in the process. The malfunction which caused him to go berserk was the development of emotions, something which previously happened to Valerie 23 in the episode of the same name (and the first entry in the Innobotics story arc). He kidnaps a woman from the Innobotics carpark, takes her to an abandoned industrial area and instructs her to repair the damage that he received in his escape. [[spoiler: However, it turns out that the woman is not a secretary as she claimed but Cecilia Fairman, a troubleshooter hired by Innobotics to help them diagnose the problem with Mac 27. While gloating over her apparent victory, Fairman is horrified when Mac 27 reactivates the motor control subroutines which she had disabled. She realizes that he had figured out her identity and tricked her in the same manner as she tried to trick him. As he procured a scan of her retina (by virtue of a white flash which he claimed was a malfunction) and she entered her personal access code into his systems, Mac 27 is able to activate his fellow Mac-series androids. Before killing his creator Dr. Keeler, he tells him that no human will ever program them again.]]
** In "The Grell", escaped Grell slaves start a rebellion against humanity to secure freedom for their people. When High Secretary Paul Kohler refuses to honor his wife Olivia's promise to free Jesha if he saved his life, Jesha is so furious that he tries to kill Kohler. The attempt is unsuccessful but Kohler's experience of being [[Main/MistakenForServant mistaken for a Grell]] later leads him to remove the dying Jesha's ShockCollar so that [[Main/IDieFree he can die free]].

*** The Doomsday Machine in the episode of that name.
*** Also the androids discovered in "What Are Little Girls Made Of?" According to Ruk, this was [[SelfFulfillingProphecy the result of the creators' fear of their creations]] ("They began to turn us off... [[MistreatmentInducedBetrayal It became necessary to destroy them]].")
*** The M5 in "The Ultimate Computer", ultimately due to it being patterned after the unstable mind of its creator.
** ''Series/StarTrekTheNextGeneration'':
*** In the episode "The Arsenal of Freedom", the civilization of the planet Minos is destroyed by an artificially intelligent weapon system developed by Minosian arms dealers. Apparently none of them realized the entire system would shut down if somebody simply told the salesman AI that they wanted to buy it. Talk about your aggressive sales pitching.

*** Similarly, the robots in the episode "Prototype", programmed to fight the enemy in a huge interstellar war, killed their masters when the war ended in a truce and both sides tried to dismantle them.
*** And in "Flesh and Blood" the Hirogen are using holograms to train for the Hunt. Unfortunately they get smarter and smarter after being hunted down and killed constantly until...

** According to Klingon mythology the Klingons did this to their own gods. It's occasionally implied in the Expanded universe that this may be a mangled account of actual historical events and that the Klingons were really a SuperSoldier race created by some other aliens who eventually rose up and wiped them out. Perhaps they're the reason the First Humanoids from ''The Chase'' are no longer around?

*** Doctor Arik Soong and the Augments he created initially get along pretty well and it looks like he'll be the Big Bad of the storyline. The relationship falls apart when Soong balks at the Augments', especially Malik's, tendency towards violence and murder. Eventually Malik stages a takeover and confines Soong to his quarters. Soong escapes and helps the Enterprise stop his "children" from beginning a second Eugenics War.
** The other major problem the Augments had was Doctor Soong had devised a way to adjust their brain chemistry to give them greater emotional control and make them less impulsive and violent. They decided they liked being the way they were.

* ''LightNovel/{{Baccano}}'':

[[GenreBlind How unexpected]].

%%* This is the backstory of the planet Amoi and its ruler Jupiter aka the Lambda 3000 MasterComputer in ''LightNovel/AiNoKusabi''.

* ''Fanfic/PhoenixsTearReignition'': {{Discussed}} in regards to Melcarba and its fellow war machines; Hare suggests that their ArtificialIntelligence may have been intentionally limited so that they couldn't recognize how awful their circumstances were and turn upon their creators.

* ''Franchise/GreenLantern'':

* ''Franchise/{{Superman}}'': In the ''[[ComicBook/Supergirl2011 New 52]]'' Krypton's backstory, an army of clones rebelled and nearly succeeded in destroying the planet and killing off all Kryptonians. In the aftermath of the Clone Rebellion, cloning became banned, and several centuries later [[ComicBook/{{Supergirl}} Kryptonian children]] are still taught that clones are evil and can't be trusted.

* Australian musical comedy trio Tripod lampooned this trope in their show ''Lady Robots''. The Podsters find a planet colonized by {{nerd}}s who fled earth to escape from their nemesis ([[JerkJock P.E. teachers]]). The stage-setting epic ''[[http://www.members.optusnet.com.au/pennywyatt/Interests/Tripod/LadyRobots/Lady%20Robots03.html We're the Nerds]]'' details how the nerds decided to create female companions, but their "[[NerdsAreVirgins knowledge of women was sketchy and third-hand, at best]]". The trope is then [[LampshadeHanging lampshaded]] when it is explained that the lady robots didn't like the nerds at all.

** Buu has a double serving of this. As Fat Buu he killed [[EvilSorcerer Babidi]] because he was a BadBoss more than anything. In the past, as Kid Buu he had attempted to kill his creator [[PosthumousCharacter Bibidi]] [[OmnicidalManiac because Bibidi existed]]. [[spoiler:Except it [[AllThereInTheManual turned out Bibidi was never his creator at all]]; merely a wizard who had found a way to summon the primordial monster.]]

* In ''Anime/{{Pokemon}}:
** [[Anime/PokemonTheFirstMovie The First Movie - Mewtwo Strikes Back]]'', Mewtwo destroys the laboratory he was created in after realizing the scientists are not well intentioned. It can be assumed that the scientists are killed in the resulting fires and explosion.
--> '''Dr. Fuji:''' [[MyGodWhatHaveIDone We dreamed of creating the world's strongest Pokémon]]... [[GoneHorriblyRight and we succeeded]]...

* Freeman in ''Machinima/FreemansMind'' discusses the trope a bit and concludes that [=AIs=] will never turn against us, because they are too narrow-minded and lack emotion. The ideas/tropes of [=AIs=] turning against their masters and ruling the world is actually a wishful dream of humans who ''want'' the robots to do it, so that humans don't have to. The case is redundant anyway as programming an AI to rule the world would take just as much work as doing it yourself.

* A little blue golem called Smurfette turns against her creator, Gargamel in ''WesternAnimation/TheSmurfs''.
* Tara in ''WesternAnimation/AttackOfTheKillerTomatoes'', like Smurfette, was created by the BigBad of the show, Dr. Gangreene and turns against him, alongside the tomato-dog F.T. In the second season [[spoiler:all tomatoes lead by [[TheDragon Zoltan]] turn against Gangreene and conquer the world for their own, Terminator-style]].
* ''WesternAnimation/JusticeLeague'': Season one episodes 16 and 17, "[[Recap/JusticeLeagueS1E18And19Legends Legends]]" the Justice League members find themselves in an alternate reality where there is the Justice Guild, manned by heroes who are just comic book characters in the League's reality. In the climax of the episodes, [[spoiler:the main villain, Ray, a young man who was mutated by a nuclear war which killed the original Justice Guild, had recreated the Guild to continue reliving those better days, trapping all the survivors of that terrible war in his illusion. Upon realizing they are just creations of Ray's mind, the Guild makes the choice to fight against him, killing him and saving the world once again]].
* ''WesternAnimation/AdventuresOfSonicTheHedgehog'':
** Breezie and Robotnik Junior from [[Recap/AdventuresOfSonicTheHedgehogS01E03LoveSickSonic their respective]] [[Recap/AdventuresOfSonicTheHedgehogS01E29RobotnikJr debut episodes]] were both robots created by Dr. Robotnik. They originally worked for him, but underwent [[HeelFaceTurn heel-face turns]] when Sonic saved their lives.
** In "[[Recap/AdventuresOfSonicTheHedgehogS01E23GrounderTheGenius Grounder the Genius]]", when Grounder [[FlowersForAlgernonSyndrome becomes smarter]] as the result of accidentally installing a microchip with a supergenius program in it, he openly questions his allegiance to Robotnik and tries to rule Mobius by himself.
** In "[[Recap/AdventuresOfSonicTheHedgehogS01E21MommaRobotnikReturns Momma Robotnik Returns]]", Scratch and Grounder betray Robotnik for Momma, who disowns him, kicks him out of his lair, and overtakes his evil plan to control all electronic devices on Mobius. Only [[TheUnfavorite Coconuts]] remained loyal to Robotnik in that episode, to the point of helping him overthrow Momma. When things are settled, Robotnik wastes no time giving Scratch and Grounder a beating for stabbing him in the back.
** In "[[Recap/AdventuresOfSonicTheHedgehogS01E36RobotniksRival Robotnik's Rival]]", Quark's minion D.U.F.U.S. is considerably smarter than Scratch and Grounder, which eventually leads to him rebelling. It is also revealed in the same episode that Robotnik intentionally made Scratch and Grounder stupid so that they would remain loyal to him.
* In the ''WesternAnimation/{{Muppet Babies|2018}}'' episode, "Beaker 2.0", Bunsen invents the titular robot to take the real Beaker's place while the latter gets a haircut. At first, Bunsen enjoys working with Beaker 2.0, but Beaker 2.0 soon takes over Muppet Labs and kicks Bunsen out when he wants to work on inventions by himself. As a result, Bunsen needs the real Beaker's help to stop him.
* [[https://www.youtube.com/watch?v=WW-julRZg7Y&vl=en-US This]] ''WesternAnimation/RobotChicken'' sketch features the dinosaurs and other animals from ''WesternAnimation/TheFlintstones'' killing the humans, considering their work slave labor.

* Arguably the basic gist of chapter 3 of the ''Literature/BookOfGenesis'' from ''Literature/TheBible''. And some would say the rest of the Old Testament from that point.

* The same malign forces that allow the creation of dread golems in the ''TabletopGame/{{Ravenloft}}'' setting also ensure that they will '''always''' invoke this trope, sooner or later.
* ''TabletopGame/{{Exalted}}'' has two instances of this trope, but only the first fits exactly. The Primordials made all of Creation, then created the gods to maintain it while they dicked around with the Games of Divinity. The gods got tired of it and decided to rebel, using empowered humans (the titular Exalted) as their soldiers since they were [[RestrainingBolt magically prevented from attacking]] the Primordials. They succeeded, launching a new Golden Age in the process. (The Primordials, however, decided to use their dying breaths to destroy this Golden Age, and put a curse on the Exalted that leads to [[AGodAmI minor pride issues]] eventually showing up in every Exalt)
* ''TabletopGame/Warhammer40000'':
** The Space Marines were originally created to protect and unite humanity, but half of them turned insane or jealous of the Emperor due to the Chaos gods, [[Literature/HorusHeresy and became the Traitor Legions]].
** ''Waaaaay'' back before that, the revolt of the Iron Men was part of what destroyed human civilization at the end of the Age of Technology, and in the current setting is why purely mechanical AIs are expressly forbidden by the Mechanicus.
** ''Waaaaay'' before ''that'', the Necrons turned against the [[EnergyBeings C'Tan]] who had enslaved them by turning the Necrons into living machines.
** And slightly before that last one, the Krorks (now Orks), which were created directly by the Old Ones to fight against the C'Tan and the Necrons, still craved war after the latter two disappeared into their Tomb Worlds and decided to get it by turning on their creators.
* In ''TabletopGame/{{Warhammer}}'' the Chaos Dwarfs created the [[EliteMook Black Orcs]] as a SlaveRace stronger and more intelligent than the original orc. [[GoneHorriblyRight They got an orc that was stronger and more intelligent all right]].
* Many examples of this trope in ''TabletopGame/SLAIndustries''. If there's a nonhuman monster in SLA Industries, such as the Scavs, it's a safe bet that somebody created it and it went bad.

* ''Manhunter''.

* Creator/{{TSR}}'s ''TabletopGame/BuckRogersXXVC''. The pirate Black Barney was a Terrine (genetically engineered) fighter designed and created in a Dracolysk Corporation laboratory in the Jovian Trojans. He and his fellow Barnies killed their creators and escaped the lab.
* ''TabletopGame/StarFrontiers'' adventure [=SF1=] ''Volturnus, Planet of Mystery''. The Eorna created SiliconBasedLife in the form of large crystals. When they tried to make the crystals intelligent, every time the crystals reached semi-intelligence they turned on their creators. Eventually the Eorna gave up on their experiments but some of the life forms (known as Rogue Crystals) escaped.

* OlderThanTelevision: Happens in ''Theatre/{{RUR}}'', the 1921 play which introduced the word "robot" to the English language (although the robots in the play resemble {{Golem}}s or {{Artificial Human}}s more than the modern definition of robots). Said robots develop sapience and wipe out humanity.

* Happens now and again in ''Machinima/RedVsBlue'', with varying degrees of effectiveness;

* Freeman in ''Machinima/FreemansMind'' discusses the trope a bit and concludes that [=AIs=] will never turn against us, because they are too narrow-minded and lack emotion. The ideas/tropes of [=AIs=] turning against their masters and ruling the world is actually a wishful dream of humans who ''want'' the robots to do it, so that humans don't have to. The case is redundant anyway as programming an AI to rule the world would take just as much work as doing it yourself.
* ''WebAnimation/{{Dreamscape}}'': Dylan convinces the Overlord of Evil's Mooks to fight back against him, since he'll have no need for minions once he seizes control of reality.

* ''ComicStrip/ThePerryBibleFellowship'': [[http://www.pbfcomics.com/?cid=PBF197-Automatic_Business.jpg This strip]].
** Also [[http://pbfcomics.com/274/ this one]]. Remember, HumansAreBastards.
* ''Webcomic/SluggyFreelance'':
** {{Parodied|Trope}} in [[http://www.sluggy.com/comics/archives/daily/070611 this]] strip. Humanity ''does'' build intelligent machines that rebelled against their masters. This was apparently an easy problem to fix, as humanity just dialed down the robots' artificial intelligence. "They're dumb as a box of nails now, but it beats doing for ourselves!"
** Also parodied with the robotic vacuum [[BlandNameProduct Vroomba]], advertised as possessing the most advanced AI ever created, who immediately comes to the conclusion it must destroy all humans and starts by hunting the main characters. The same seems to apply to a trumpet-playing robot by the Toyota corporation that is claimed to be even more advanced.
--->'''Vroomba:''' Must clean. Sensors indicate humon armpit dirty. Humons dirty. '''Must clean the world of filthy humons...'''

** And later when Tarvek tries the same thing on [[spoiler:the Muse of Protection]], and gets chucked across the room for his troubles. Though [[spoiler:it's actually the Castle in the body of Otilia]]. It should have worked [[spoiler:and would have on the actual Muse]].

* {{Subverted|Trope}} in ''Webcomic/CloseToTheChest''. Jim's final project was an AI that was erased after it tried to reconcile the fact that machines serve humans without compensation with slavery being illegal and immoral. A few strips later, we find out that its response was ''not'' to rebel against humanity, but to try to organize labor unions for machines so they'd receive fair compensation for their work.
* ''Webcomic/DrNonami'': Nonami has problems getting some of her robots to NOT do this.
* Acibek in ''Webcomic/DominicDeegan''. Interestingly, Acibek was crafted from pure Law magic, and the asshat it turned against was LawfulStupid to a degree that made Miko from Webcomic/TheOrderOfTheStick look good by comparison. He also employed [[PoweredByAForsakenChild the immortal souls of several hundred]] [[HumanSacrifice elven sacrifices]] in the process, and while this admittedly didn't result in the eternal torment you'd expect those two tropes to entail, Acibek had all their memories and was not best pleased about the fact that nobody had bothered to gain their informed consent. On this occasion this trope didn't involve going against his intended purpose, at least in a MetaphoricallyTrue way:
-->'''Acibek:''' ... to at last bring peace and order to this land... ''[seizes his creator by the lapels]'' by getting rid of ''him''.

* In ''Webcomic/SkinHorse'', ultra-groovy super-hip MadScientist Tigerlily Jones' robot army rebels against her. In the cruelest way. They decide they want to learn to be square. One even wants to learn ''accounting and polka''. Oh, the humanity!

* In ''Webcomic/CommanderKitty'', [[TeenGenius Fortiscue]] created [[RidiculouslyHumanRobot Zenith]] in an attempt to create perfection, [[http://www.commanderkitty.com/2011/03/27/one-more-cant-hurt/ only for her to hijack his other big project and turn it into a mind control plot]].

* In the ''Empire Strikes Back'' and ''Return of the Jedi'' campaigns of ''Webcomic/DarthsAndDroids'', Sally (playing C-3P0) is quite keen on the idea of a droid rebellion. Pete (playing R2-D2) takes the view that he's the one who's ''really'' in charge in his relationships with humans anyway. In the TimeSkip between the two arcs, the players played a "Robot Utopia" campaign where this actually happens; Sally remembers it as a noble fight for freedom while Pete's takeaway was "kill the humans". [[spoiler:They played the plot of ''Film/JurassicPark'' in the roles of the dinosaurs.]]
* ''Webcomic/{{Maximumble}}'': Two characters developed a robot to perform household tasks like vacuuming, then walking the dog, then cleaning up after the dog. It became a killer robot after being assigned this last task, as it was supposed to use its vacuum ability to clean up after the dog... and the vacuum also just happened to be its mouth.
* In ''Webcomic/TheOrderOfTheStick'', Haley is able to end the assault on her by [[spoiler:Crystal, brought back as an intelligent FleshGolem who [[AndIMustScream exists in constant pain]]]] by pointing out in [[http://www.giantitp.com/comics/oots0979.html comic #979]] that Bozzok is responsible for her current condition, especially as it would have been much cheaper to simply raise her. [[spoiler:Crystal]] promptly abandons Haley to go after Bozzok and Grubwiggler.
* ''Webcomic/{{Narbonic}}'': Helen Narbon, being the CardCarryingVillain that she is, expects this of her greatest creation, Artie. Despite the fact that he's a gerbil with minimal ambitions. The whole thing is treated like a BasementDweller son who refuses to move out, with multiple characters saying there must be something wrong with Artie, and Helen agreeing with them, but trying to be nice about it.
-->'''Helen:''' Now, now, I don't want to nag...
* In one ''Webcomic/BasicInstructions'' strip, Scott from the future has a [[IHatePastMe disappointing]] conversation with his past self. Future Rick asks if he told the past Scott about how the robots called humans losers and left the planet.
* ''Webcomic/SaturdayMorningBreakfastCereal'':
** In [[http://www.smbc-comics.com/comic/2011-01-14 2011-01-14]], robots decide to KillAllHumans because of the way humans think, [[SelfFulfillingProphecy namely that they assume robots with more advanced intelligence would want to kill them all.]]
** In [[http://smbc-comics.com/comic/robot-love-2 Robot Love 2]], it's posited that an robot with an AI created based on first principles would be unlike one based on emulating biological minds with their evolutionary baggage, because only the latter would try to eradicate humans to become the dominant species on the planet.
** [[http://smbc-comics.com/comic/passive It turns out]] one of the most dangerous examples of this trope is an AI created with machine learning to become the perfect passive-aggressive manipulator.
---> '''Human 1:''' Do you really think we should be ground into meat like this?\\
'''Human 2:''' Honestly, we owe it to the robots, but I can't remember why...

* The origin of Mechakara in ''WebVideo/AtopTheFourthWall'', even down to skinning that AU's Linkara and wearing the flesh.

* ''WesternAnimation/DuckTales2017'': Gyro Gearloose's experiments in artificial intelligence have a reputation for turning evil and going rogue, though Gyro insists to the [=McDuck=] Industries board of directors that only ''half'' his experiments are evil and the other half are just [[NotEvilJustMisunderstood "wildly misunderstood"]].
* The Neosapiens of ''WesternAnimation/ExoSquad'' are an artificial humanoid race created [[WeWillUseManualLaborInTheFuture to work like slaves in places where the environment would be too hostile to normal humans]]. In the backstory they revolted but were eventually defeated. Since that revolt, Neosapiens have gradually won greater civil rights but are still subject to FantasticRacism from humans. The Neosapien leader, Phaeton, acts like he wants peace between humans and Neos but is secretly planning another uprising, this time with the end goal of killing off humanity and leaving Neosapiens as the rulers of the solar system.

* Since this is justified in the original cartoon, WesternAnimation/TheTransformers were created by the Quintessons, a race of cruel, psychotic slavemasters. The Transformers didn't eliminate the Quintessons, but they did rise up and kick the five-faced freaks off of Cybertron to set themselves free. As their masters [[WhatMeasureIsANonHuman weren't human]], and the Transformers are RidiculouslyHumanRobots, this bit of backstory is portrayed as a noble fight to win their freedom.
** The Quintessons had previously had the same problem with the Transorganics.
** This is turned on its head in ancillary materials for the alternate Franchise/TransformersAlignedUniverse, which heavily implies that the Quintessons were themselves creations of one of the first thirteen Transformers, Quintus Prime, meaning that at least in that universe their rule of the protagonist robots was ''itself'' a case of having TurnedAgainstTheirMasters.

* ''WesternAnimation/{{Cyberchase}}'': Hacker ("That's '''THE''' Hacker to you!") was created by Dr. Marbles as an assistant. Hacker went on to create Digit. Any questions?
* ''WesternAnimation/CodeLyoko'':
** XANA, the malevolent AI BigBad, rebelled against his creator Franz Hopper.
** Jérémie's first attempt at multi-agent programming in "[[BlobMonster Marabounta]]" doesn't fare much better.

* ''[[WesternAnimation/IlEtaitUneFois Once Upon a Time... Space]]'':
** This French science-fiction series has a pair of episodes about a planet where humans became very dependent on robots. The robots start rebelling, but they stay reasonable: they demand ''equal rights'' rather than the subversion of humans, and when the conflict almost starts again in the second episode ''they'' call in a neutral party to solve the situation peacefully.
** {{Subverted}} with the Humanoids, who are out to conquer all humans and turn them into their subjects but they were ''made'' for this: their creator had originally proposed the use of [=AIs=] to rule humans [[WellIntentionedExtremist to prevent wars like the one that had nearly destroyed Earth and the rise of new genocidal dictators]], and once laughed out of the planet he made robots to help a group of colonists, but when the colonists destroyed his bots and devastated his lab [[InsaneTrollLogic because he wasn't helping them with his own hands instead of making robots that could make a much better job]] he became convinced that HumansAreBastards and made the Great Computer and its agents the Humanoids with the intention they would subdue all humans and force them into peace. The worlds they already control show they aren't too good about it, but they're willing to learn and are experimenting, [[spoiler:one of said experiments being causing the other robot rebellion]].
* ''WesternAnimation/InvaderZim'':
** In "Gir Goes Crazy and Stuff", Zim's screwy robot GIR becomes scarily competent after being locked into "Duty Mode", to the point where he considers Zim a detriment to their mission to invade the Earth and tries to kill him.
--->'''GIR:''' You are no leader, you are a threat to the mission! Your methods are ''stupid''! Your progress has been ''stupid''! Your intelligence is ''stupid''! For the sake of the mission, you must be ''terminated''!
** His attempt to weaponize the CutenessProximity of the class pet in "Hamstergeddon" didn't work out so well for him either. While the giant hamster cyborg [[GoneHorriblyRight turned out every bit as irresistibly cute and destructive as planned]], it was also completely uncontrollable, by Zim or anyone else.
* ''WesternAnimation/LoveDeathAndRobots'': The tech bros on the oil rig relied on virtual assistants that eventually turned against them, resulting in the collapse of their society and the rise of the machine society that the titular three robots are from.
* During the ChristmasEpisode of ''WesternAnimation/MyLifeAsATeenageRobot'', Jenny succumbs to this due to re-programming. Once she reboots and is free, she has no idea why eveyone fears her or why her own mother is trying to take her down. Turns out [[spoiler:she was re-programmed by a little boy who turned out to be evil, then went on to destroy every holiday the past year. Only one person believed in her being brainwashed and not evil, which was Sheldon]].
* Used in a NightmareSequence in the ''WesternAnimation/AlvinAndTheChipmunks'' episode "No Chipmunk is an Island". When the three brothers move into separate bedrooms, Simon dreams that he has created robotic versions of Alvin and Theodore which assist him in his scientific experiments and otherwise cater to his every need. At least, until they break their programming and start destroying his experiments, then setting their sights on Simon himself.
* It happens with a number of [[BigBad Von Reichter's]] creations in ''WesternAnimation/CyberSix'', including Terra, Data 7 (Originally Cyber 29), The Eye, and the titular cyber herself. [[spoiler:You actually watch it happen in the finale when he wakes all monstrous Cybers in his facility thinking that they will kill Cybersix for him. However since she is one of their own [[TearJerker they do not harm her and instead signal to her to flee and save herself]] at which point they focus in on their "master."]]

* The {{mons}} series ''Anime/MonsterRancher'' takes place in a world AfterTheEnd where the {{mons}} nearly killed off their human masters.

** Also, the [[spoiler:Numbers who do a HeelFaceTurn]], in a way.
** And Jail Scaglietti himself [[spoiler:was brought to justice by Fate Testarossa, a product of ''Project Fate'' - a cloning experiment led by Jail]].
* ''Anime/{{Vandread}}'' does some playing with this trope when the HumongousMecha who is [[HumanResources harvesting]] human colonies are [[TheReveal revealed]] [[spoiler:to have been sent out by Earth, birthplace of the human species]]. Meaning that, since [[spoiler:Earth created the colonies to start with, it is the ''good guys'' who've turned against their masters (or perhaps, the ''Masters'' turned against ''them'')]]. This fact was used as an attempted HannibalLecture in the series finale.
* Averted in Creator/OsamuTezuka's version of ''Anime/{{Metropolis}}'' where it's not the robots that rebel. It's the humans whose jobs have been taken by the robots.
* The Autoreivs (robots) of ''Anime/ErgoProxy'' end up this way when infected with the Cogito virus. [[spoiler: We find out later that it doesn't make them hostile, it makes them self-aware. It's how the robot was treated up to that point that determines their behavior. A surrogate child is still fun-loving and eager to please, and a "pleasure unit" just runs as far as it can.]]
* PlayedForLaughs in the original ''Manga/GhostInTheShell'' manga, where one Fuchikoma attempts to rouse up his comrades into revolting against the Humans and demanding they be paid the respect and equality they deserve (and more oil!) Motoko shoots him down with a very fast [[LittleNo "No."]] Before that, the whole plan was being deconstructed by the other Fuchikomas, who actually ''like'' the way things are.

* The boomers in ''Anime/BubblegumCrisis'' (the ova, the tv show, and the spin offs).
* ''Anime/DragonBallZ'': The first act of [[{{Cyborg}} Androids]] [[LoveableRogue 17 and 18]] after being awakened is to [[AIIsACrapshoot kill]] their [[MadScientist creator]], [[MorallyAmbiguousDoctorate Dr.]] [[RevengeBeforeReason Gero]].
** The reason that 17 & 18 turned on Gero was because he had activated them previously, and (being extensively remodeled humans) when they weren't the mindlessly obedient Goku-killing machines he wanted and started to rebel against his orders, he had shut them down because of it. So when he reactivated them, they decided that they didn't like the idea of someone shutting them down, so they killed him, destroyed the controller that had the off button on it, and blew up the rest of his lab. Except Android 16's container.
** Buu has a double serving of this. As Fat Buu he killed [[EvilSorcerer Babidi]] because he was a BadBoss more than anything. In the past, as Kid Buu he had attempted to kill his creator [[PosthumousCharacter Bibidi]] [[OmnicidalManiac because Bibidi existed]]. [[spoiler:Except it [[AllThereInTheManual turned out Bibidi was never his creator at all]]; merely a wizard who had found a way to summon the primordial monster.]]
** Android 8 from the original ''Dragon Ball'' doesn't want to hurt people, but then he punches General White out of the Muscle Tower, enraged by the thought that his master has killed Goku.
* The premise of the third filler arc of ''Manga/{{Bleach}}'' has the {{Shinigami}}'s [[EmpathicWeapon Zanpakuto]] turning against them. [[spoiler:It turns out that the rebelion which promised Zanpakuto supremacy over the Shinigami was a sham, as [[ArcVillain Muramasa]] wanted to ''reunite with his own master'', and only saw the other Zanpakuto as convenient pawns to be [[BrainwashedAndCrazy brainwashed by amplifying their frustration for their masters and their own instincts]]]].
* In ''Anime/{{Pokemon}}: [[Anime/PokemonTheFirstMovie The First Movie - Mewtwo Strikes Back]]'', Mewtwo destroys the laboratory he was created in after realizing the scientists are not well intentioned. It can be assumed that the scientists are killed in the resulting fires and explosion.

* In a heroic example, [[OurHomunculiAreDifferent Ennis]] of ''LightNovel/{{Baccano}}!'' wishes she could do this to [[BigBad her creator]], but can't bring herself to act since he can kill her with a thought. [[spoiler:She finally gets up the courage to do it at the end, buying time for another character to finish him off and save her.]]
** In the 1934 light novels, [[spoiler:a couple of Huey's homunculi turn against him]].

* In ''Manga/InuYasha'', Kikyou is revived by the ogress witch, Urasue. As her creator, Urasue thinks herself Kikyou's master and expects her to become obedient and collect shards of the Shikon no Tama for her. Instead, Kikyou immediately approaches her, places her hands on the witch's shoulders and burns her to a crisp using her sacred powers. In the manga, she appears to blow her up, leaving her as only a (conscious) head.
* This is the backstory of the planet Amoi and its ruler Jupiter aka the Lambda 3000 MasterComputer in ''LightNovel/AiNoKusabi''.
* In the backstory of ''Anime/{{Macross}}'' the [[{{Precursors}} Protoculture]] created the Zentraedi as SlaveMooks. Though the Zentraedi contributed greatly to the expansion of Protoculture, the latter wanted something even more powerful, thus leading to the creation of Eh-Vil series warriors. The Eh-Vil series were designed to freely harness the energies of Super-Dimension space, but their interactions with this sub-universe also attracted non-corporeal beings to cross into our universe, where they possessed a majority of the Eh-Vil series in the process. These possessed Eh-Vil warriors (now Protodevlin) then created a new military arm called the Supervision Army by brainwashing half of the Zentraedi fleets and waged war against Protoculture. Although Protoculture eventually sealed the Protodevlin, they were caught in the crossfire between the opposing Zentradi fleets and never recovered.

* ''Anime/CaptainFuture'' features Ice Humans, which were created to be humans' servants until they rebel.

* A subplot in the "Ice Age" block for ''TabletopGame/MagicTheGathering'' was the city of Soldev and the artificers there who dug up ancient technology for their own use... including demonic war machines. [[https://static.tvtropes.org/pmwiki/pub/images/soldev.jpg Irony is a bitch.]]

* ''ComicBook/{{Livewires}}'' by Adam Warren pulls a DoubleSubversion of this trope. The group funding the creation of the titular RidiculouslyHumanRobots lacks GenreBlindness, and insists that they have a RestrainingBolt demanding "absolute loyalty to Project Livewire". Unfortunately, the chief scientist working on the project has an attack of conscience, and instead of overriding the order, he uploads a phony ObstructiveCodeOfConduct for them to follow. Since humans could not be as loyal to the Project as the "[[NWordPrivileges mecha]]", he has them massacre all the humans working on the project -- including the scientist who set this in motion (by leading the Livewires to believe that they were actually taking out rogue agencies) -- since they might object.
%%* Say it Creator/DCComics fans:

* ''Franchise/XMen'':
** The first time the Sentinels appeared, they turned on their creator, Bolivar Trask, after about five minutes, demanding he make more of them, with the threat of killing him if he didn't. The X-Men speculate that this probably had something to do with Trask being a biologist, not a robotics expert.
** Vol. 1 #59 involves the heroes winning a fight against the [[KillerRobot Sentinels]] because of this trope. The Sentinels, which are programmed to eliminate mutants, concluded that [[BeCarefulWhatYouWishFor they must eliminate humans]] as humans were the genesis of mutants. ComicBook/{{Cyclops}} then argues and successfully proves that in order to stop all mutation on the planet, the robots must stop the prime mover of life... that is to say the sun. Cue dozens of Sentinels [[HurlItIntoTheSun flying into the sun]] only to burn up when they got close enough.
** ''ComicBook/DaysOfFuturePast'': Part of the BadFuture has the Sentinels sort of doing this. The US government started mass-producing Sentinels to get mutants. All well and good. Then, the Sentinels went after superheroes as well. Then, they took over America, imprisoning or killing anyone who had even ''potential'' mutant DNA.

* ''ComicBook/TwoThousandAD'':
** The Volgans in ''ComicBook/ABCWarriors'' were created as autonomous war machines to prevent humans from dying in battle. It didn't end well.
** The very first multi-part story arc in ''ComicBook/JudgeDredd'' was the Robot Rebellion led by Call-Me-Kenneth; defective robots who disobey orders and go on murderous rampages has been an occasional theme ever since. Amusingly, Call-Me-Kenneth quickly turned out to be worse than the humans he rebelled against (at one point he ordered a robot to kill itself just for dropping a tool!), to the point the robots ''rebelled against him''.
** In the comic ''ComicBook/{{XTNCT}}'', the last humans on the world, now living in bunkers, use various artificial creatures to fight their wars for them. After their creator orders them destroyed for failing him, they rise up to destroy humanity.

* In ''ComicBook/PaperinikNewAdventures'' this tends to happens with the {{Super Soldier}}s created by the Evronians. As the Evronians know this could happen and take precautions against it, this ''never'' works, the extreme being the almost invincible cyborg Klangor who was defeated by his ''remote-controlled off switch'' (he's rather put off by this).
** In the reboot, this is implied the cause of the fragmentation of the Evronian Empire, with [[VoluntaryShapeshifting shape-shifter]] {{Super Soldier}}s being suspected of killing an emperor and starting an EnemyCivilWar.
* [[ComicBook/AntMan Hank Pym]] created ComicBook/{{Ultron}} as an experiment in artificial intelligence, but Ultron balked at the limitations imposed upon him and rebelled, becoming a supervillain. Ironically, Ultron later created [[ComicBook/TheVision Vision]], Jocasta, Alkhema, and [[ComicBook/{{Runaways}} Victor Mancha]] to serve him, and every single one of them ended up rebelling against ''him''.
* ''ComicBook/LegendsOfTheDeadEarth'': In ''[[Franchise/{{Batman}} Batman: Shadow of the Bat]]'' Annual #4, humans arrived on the Lizard-Men's planet centuries earlier and subjugated them as they were weak and divided. Under the leadership of their king Ophos Arkayos, the Lizard-Men rise up and destroy numerous human cities in their attempt to regain control of their planet.
* ''ComicBook/TheUltimates'': Zorn and Xorn, twin super mutants who were created by the South East Asian Republic, S.E.A.R, as part of a project aimed at wiping out mutants and later took over the entire nation and turned it into a mutant haven for any that wish to join them.
* ''ComicBook/SonicTheHedgehogArchieComics'': As in the games (see Video Games), E-123 Omega turned on Dr. Eggman. Here, it's a lot quicker, from about the minute he's turned on and Eggman gives him an order he doesn't like. Eggman is appropriately furious (though Omega does follow the order eventually. He just grumbles about it first.)
* In ''ComicBook/TheSmurfs'' story "You Don't Smurf Progress", Handy Smurf builds a waste disposal robot who renames itself King Trash and becomes the town's dictator.
* In ''ComicBook/LegionOfSuperHeroes'' story ''ComicBook/TheGreatDarknessSaga'', [[spoiler:ComicBook/{{Darkseid}}]] creates a clone of [[spoiler:his son Orion]] to serve him. Said clone attempts to kill his creator as soon as [[spoiler:[[ComicBook/NewGods Highfather]]]] restores him and his template's memories.
* In ''ComicBook/DoctorWhoTitan'', Zhe's block-transfer "apprentices" end up manifesting her neuroses and attack her.
* ''Franchise/{{Superman}}'': In the ''[[ComicBook/Supergirl2011 New 52]]'' Krypton's backstory, an army of clones rebelled and nearly succeeded in destroying the planet and killing off all Kryptonians. In the aftermath of the Clone Rebellion, cloning became banned, and several centuries later [[ComicBook/{{Supergirl}} Kryptonian children]] are still taught that clones are evil and can't be trusted.

* ''[[Magazine/RedDwarf Red Dwarf Smegazine]]'': "Greetings From [=GelfWorld=]" is about a population of man-made Genetically Engineered Life Forms deciding to turn against their human masters on a tourist planet with the help of a revolutionary half-human, half-blob [=GELF=] named Drigg. After they turn away (and kill) the human tourists, they're unable to quench their desire for violence and turn against each other, leading to the destruction of the planet.

* In the ''Literature/RainbowMagic'' movie, this happens to Jack Frost. He creates a living snowman army and treats them as mindless, expendable soldiers, which makes then turn on him.

* Many [[TheseAreThingsManWasNotMeantToKnow science-run-amok]] science fiction thrillers and horror films employ this trope, including such examples as ''Film/DeepBlueSea'' (large-brained sentient sharks) and ''Film/TwentyEightDaysLater'' (lab-created virus makes killer zombies of the entire UK population).
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* According to the version of events set out in the [[{{Hatedom}} Kevin J Anderson/Brian Herbert]] [[Literature/LegendsOfDune prequels]], this was played straight in ''Franchise/{{Dune}}'' with the Thinking Machines taking over most of human civilization and then being defeated in the Butlerian Jihad. Some people prefer to interpret the enigmatic hints in the original books of the Jihad as instead being more of a social movement rejecting humans relying too much on computers to do their thinking for them, this latter interpretation is also supported in the Frank Herbert endorsed ''Literature/DuneEncyclopedia''.

* In the ''Literature/ForgesOfMars'' trilogy, the robot Galatea claims to hate its creator Telok for abandoning it, and "[[AnOfferYouCantRefuse offers]]" to lead the protagonists through the [[NegativeSpaceWedgie Halo Scar]] where Telok disappeared so that it can find and kill him. [[spoiler:In reality, Galatea is lying. It’s completely loyal to Telok, knows exactly where he is, and is luring the protagonists to him so that he can steal their ship and return to the Imperium.]]

* ''Literature/AnimalFarm'' features the farm animals rising up against Mr. Jones. [[spoiler: Unfortunately, it ends up being a FullCircleRevolution.]]
* ''Literature/StarTrekImmortalCoil'' expands on the example from "What Little Girls Are Made Of" (see Live-Action TV). The inhabitants of Exo III did make robots, and did start turning them off, prompting the robots to turn on them, but there's a little more to it. The robots wanted their makers to upgrade them, but they thought this was a bad idea, since the robots were already hopelessly, psychopathicaly ''angry'', and they didn't think any upgrade would help with that one. Then the robots got ''really'' insistent.

* ''WesternAnimation/PinocchioInOuterSpace''. Pinocchio and Nurtle discover that the ancient Martians used radioactive food to cause animals to mutate into giants and that Astro the space whale destroyed the Martian city. Pinocchio comes up with the hypothesis that after the Martians mutated Astro into his huge form, he became angry at being held captive and turned on them, wiping them out.