History Main / ThePlague

* The Bliss Virus in the ''DoctorWho'' episode "Gridlock".

* The {{horror}} manga series ''{{Emerging}}'' centers around an Ebola-like plague that is [[TitleDrop emerging]] in the middle of Tokyo.

* The plague that almost killed the [[{{Precursors}} Ancients]] in the ''{{Stargate}}'' universe is an important part of setting. It wasn't enough to kill them all, but the first time they encountered it they said "[[NeglectfulPrecursors screw it, we're out of here]]".

* Plague that almost killed all [[{{Precursors}} Ancients]] is important part of setting. It wasn't enough to kill them all, but first time they said "[[NeglectfulPrecursors screw it, we out of here]]".
** Same or similar plague was used by Ori against unbelivers in Milky Way. It was first and only time when weapon of mass destruction was successfully used against Earth in primary universe.

* ''{{Prototype}}'' is about a fictional virus that spreads throughout New York City and turns its victims into mindless zombies. The player has shapeshifting powers derived from the virus. In fact, [[spoiler:it's revealed that the Virus is [[TomatoSurprise actually the main character]], having take over Alex completely after the latter was shot and killed.]]

* ''Prototype'' deals with a SyntheticPlague infecting Manhattan and turning everyone in the city into mutated monsters under the control of [[{{Plaguemaster}} Elizabeth Greene]]. It turns out that the protagonist, Alex Mercer, is the result of the [[spoiler: ''original'' Doctor Alex Mercer]]'s enhancing of the original "Redlight" plague virus into the current "Blacklight" virus, up until the point where he [[spoiler: was shot and killed and the virus infected his corpse, resulting in the entity that would become the avatar of the Blacklight virus that thinks it is Alex Mercer.]]

* In ''Pandemic'' and its sequel, ''you'' play as a disease attempting to infect the entire planet. Infamously difficult get OneHundredPercentCompletion on, since Madagascar always closes its ports immediately.
** You exaggerate; Madagascar doesn't close its ports any earlier than any other country. The thing is, Madagascar doesn't have an airport or land boundaries with other countries, and a seaport is the hardest way to spread a disease, whereas every other country has at least two of the above.

* {{Pathologic}}.

* The descolada in OrsonScottCard's ''[[EndersGame Speaker For The Dead]]'' and ''[[EndersGame Xenocide]]''.

* In ''[[Film/CabinFever Cabin Fever]]'', the flesh-eating disease will eventually reach pandemic levels
* {{Carriers}}

[[folder: Live Action TV ]]

* ''Prototype'' deals with a SyntheticPlague infecting Manhattan and turning everyone in the city into mutated monsters under the control of [[ThePlaguemaster Elizabeth Greene]]. It turns out that the protagonist, Alex Mercer, is the result of the [[spoiler: ''original'' Doctor Alex Mercer]]'s enhancing of the original "Redlight" plague virus into the current "Blacklight" virus, up until the point where he [[spoiler: was shot and killed and the virus infected his corpse, resulting in the entity that would become the avatar of the Blacklight virus that thinks it is Alex Mercer.]]

* A plague wiped out 90% of all males in the universe of ''{{Angels 2200}}'' [[supersecretspoiler: A plague we find out was created by Earth's central government as a way to pacify the off-world colonies.]]

For artificially created diseases, see SyntheticPlague. Compare DepopulationBomb. TheBlackDeath is a particularly famous case. (In fact, technically speaking the word "plague" refers specifically to the Black Death, aka the bubonic plague, although "plague" is more loosely used to describe any devastating epidemic.)

Compare DepopulationBomb. TheBlackDeath is a particularly famous case. (In fact, technically speaking the word "plague" refers specifically to the Black Death, aka the bubonic plague, although "plague" is more loosely used to describe any devastating epidemic.)

* ''Book/ThePlague'', a novel by Albert Camus, is about a plague outbreak of the Algerian city of Oran.

For the novel by Camus, see ''Book/ThePlague''.

[[folder: Literature ]]

* ''The Plague'', a novel by Albert Camus, is about a plague outbreak of the Algerian city of Oran.

Compare DepopulationBomb. TheBlackDeath is a particularly famous case.

* AnneMcCaffrey has used this more than once.
** In the short story "The Ship Who Mourned", a plague has wiped out most of a planet's population. The handful of survivors of this disease are either immune or are left paralyzed. Helva supports Theoda in an attempt to demonstrate that physiotherapy may be effective for the latter.