History Main / TheImmune

* In ''Film/{{Contagion}}'' Mitch Emhoff turns out to be naturally immune.

** In ''VideoGame/ResidentEvil7Biohazard'', both Ethan Winters and Zoe Baker are this to a degree, downplaying the trope. [[spoiler:Ethan is heavily resistant to the MindControl aspect of the mutamycete's fungal infection, and so he doesn't start to begin suffering it until the final minutes of the game. Zoe, meanwhile, seems to be completely immune to the MindControl side of the infection, which is why she is TheUnfavorite amongst her infected kin, but this doesn't protect her from Eveline's ability to simply kill off those who are infected with her fungus, even after taking the fungicidal serum.]]

* Vaccines are meant to immunize people.

* In ''Skinwalkers'' the key to curing lycanthropy are the antigens in a half-werewolf, half-human boy's blood.
* Joanie in ''Warning Sign'' is immune to the bio-engineered HatePlague because she's the only pregnant woman in the quarantined facility; the special hormones in her blood is what keeps her safe and is the basis of the cure. WhatDoYouMeanItsNotSymbolic?

* In the television version of the ''WesternAnimation/XMen'' "Legacy Virus" storyline, Cable came back in time to ensure that {{Wolverine}} would be infected with the titular virus, because his healing factor would both render him immune and lead to the creation of certain antibodies that would protect mutants from later plagues (Cable came back because Bishop's time-travelling experience prevented the virus making the jump to mutants on a large scale; infecting Wolverine was Cable's compromise so that both their goals could succeed).

* Reimi in ''VideoGame/StarOceanTheLastHope''. This is because [[spoiler:as a Seed of Hope, she is genetically engineered for survival on new and unknown worlds]]. Unfortunately, she ended up with a case of SurvivorGuilt when a radiation leak killed off all of her friends except for her.

** Non-mammals are immune to lycanthropy, so Alex calls in a wadjet (SnakePerson) doctor to help with the outbreak in Australia.

* There are some relatively rare cases of people who are totally immune to [[UsefulNotes/COVID19Pandemic COVID-19]] without any vaccination (i.e. din't catch it at all, weren't sick, weren't asymptomatic carriers and didn't produce antibodies against it).

* In the television version of the ''WesternAnimation/XMen'' "Legacy Virus" storyline, Cable came back in time to ensure that {{Wolverine}} would be infected with the titular virus, because his healing factor would both render him immune and lead to the creation of certain antibodies that would protect mutants from later plagues.

* ''Franchise/DeadRising'': Due to zombie-fighting gameplay of the series, none of the playable protagonists (or even [=NPCs=] to a lesser extent[[note]]they will only turn undead '''after''' being killed by zombies[[/note]]) ever get infected by zombie attacks in-game. In-story, some people are more resistant to the zombie virus than others; such resistants include [[spoiler:Frank West and Tyrone King]]. The apparent immunity of Chuck Greene, star of ''VideoGame/DeadRising2'', while unexplained, is a natural step up from that. ''VideoGame/DeadRising3'''s [[TheHero hero]], Nick is immune to zombification because [[spoiler:Carlito inoculated Nick with the cure instead of the zombie virus like the other orphans to ensure that his ZombieApocalypse would not be unstoppable.]]

* ''Franchise/DeadRising'': Due to zombie-fighting nature of the series, none of the playable protagonists (or even [=NPCs=] to a lesser extent[[note]]they will only turn undead after being killed by zombies[[/note]]) ever get infected by zombie attacks during gameplay. It's used as a plot point in the first three games. Some people are more resistant to the zombie virus than others; such resistants include [[spoiler:Frank West and Tyrone King]]. [[VideoGame/DeadRising3 Chuck's]] apparent immunity, while unexplained, is a natural step up from that. Nick Ramos, protagonist of [[VideoGame/DeadRising3 3]] is immune due to [[spoiler:being a secret failsafe created by the mastermind behind the zombie outbreaks]].

* In ''VideoGame/DeadRising3'', [[spoiler:protagonist Nick]] is immune to zombification. This is because [[spoiler:Carlito inoculated Nick with the cure instead of the zombie virus like the other orphans to ensure that his ZombieApocalypse would not be unstoppable.]]

* On ''Series/MyNameIsEarl'', the "Witch Lady" tried to [[SlippingAMickey drug Catalina's tea]], with the intent of storing her in the basement along with all the others she intended to kill [[DisproportionateRetribution for bullying her]]. Catalina gets down into the basement, but explains that she wasn't affected by the drug because [[FridgeHorror so many men have tried to slip her date-rape drugs in the past that she's immune to them]]. She then explains that she only pretended to be knocked out and allowed herself to be bagged and tossed in the basement is that she felt sorry for the Witch Lady.

* There was a ''Series/StarTrekVoyager'' episode where B'Elanna's unborn baby provided the cure to a Klingon disease.
** And come to think of it, she was also the source of the cure for the Vidiian Phage
** Also from ''Series/StarTrekTheOriginalSeries'', Pavel Chekov in the episode "The Deadly Years." The landing party members age rapidly, except for him, which provides the key to discovering the ImprobableAntidote.

* In Scott Westerfeld's ''Literature/{{Peeps}}'' Carriers for some unknown reason get the benefits of the parasite that causes "vampirism" while still managing to remain sane. Night vision, super strength, and long lifespans without the urge to commit cannibalism (just a craving for rare meat and a high libido) or aversion to everything they loved before infection. Unfortunately they can transmit the parasite with as little as a kiss, those who work as hunters usually start out with their exes.

* Everyone who lives through the first act of ''Literature/TheStand''. Captain Trips' initial symptoms' resemble a cold or flu, so many don't realize how sick they are without a doctor who knows what to look for, meaning the plague rapidly knocks out 99% of humanity.

* In ''[[Literature/{{Divergent}} The Divergent Trilogy]]'', [[spoiler:Tris is able to resist serums, like most Divergents. She is notably able to fight off Candor's truth serum in ''Insurgent'', and cannot be killed by the Bureau's death serum in ''Allegiant''. At multiple points, it is mentioned that her ability to resist is beyond that of most Divergents]].

* In ''Literature/TheLordOfTheRings'', Tom Bombadil is the only being completely unaffected by the One Ring (it cannot even make him vanish when he puts it on his finger), implied to be because there is nothing he desires in the world that the Ring can tempt him with. The Council of Elrond considers giving the Ring into his keeping because of this, but the problem is that the very cause of this immunity means he wouldn't be a good guardian--he wouldn't be able to appreciate how important the Ring is and would casually toss it aside and forget about it.
** As Tom doesn't seem to fit anywhere into Middle-Earth's greater cosmology (only really becomes apparent if you read ''Literature/TheSilmarillion'', where the connectedness of everything else is laid out), it's possible that the Ring doesn't work on him because he is somehow ''outside'' its influence.

* Everyone who lives through the first act of ''Literature/TheStand''.

* Dr. Robert Neville in virtually every adaptation of ''Literature/IAmLegend''.

* A big focus of ''Literature/TheAndromedaStrain'' was finding out why two people were immune to the disease when everyone else died
** What made it interesting was that they were [[spoiler:immune for similar, yet different reasons. The old man was an alcoholic, so his blood pH was acidic, and the baby was hyperventilating through crying, which made his blood pH alkaline. Turns out the Andromeda Strain could only survive within a narrow pH range]].

* The ''VideoGame/PerfectDark: Initial Vector'' novel.

* The plot of ''Film/PokemonDetectivePikachu'' involves a gaseous PsychoSerum called R, which temporarily shuts down a Pokémon's higher cognitive functions and drives them into a berserk rage. Detective Pikachu ends up inhaling the stuff at multiple points but is never effected (though the movie never draws direct attention to this). [[spoiler:That's because he's actually a FusionDance of Pikachu and Tim's father Harry. Since his mind isn't that of a Pokémon, it can't affect him.]]

* The plot of ''Film/PokemonDetectivePikachu'' involves a gaseous PsychoSerum called R, which temporarily shuts down a Pokémon's higher cognitive functions and drives them into a berserk rage. Detective Pikachu ends up inhaling the stuff at multiple points but is never effected (though the movie never draws direct attention to this). [[spoiler:That's because he's actually a FusionDance of Pikachu and Tim's father Harry. Since his mind isn't that of a Pokémon, it can't effect him.]]

* Of the few surviving humans in ''Film/DawnOfThePlanetOfTheApes'', it's stated that most are immune to ALZ-113/Simian Flu.

* The protagonist of ''Film/IAmLegend'' is one of the few humans that are immune to the disease. He spend the next three years trying to synthesise a cure out of his blood for the humans that instead mutated into the feral Darkstalkers. [[note]]In the 2007 film he's not the only immune survivor, in every [[Film/TheLastManOnEarth other]] [[Film/TheOmegaMan adaptation]] of the [[Literature/IAmLegend book]]he is the last uninfected human, ever.[[/note]]

* The protagonist of ''Film/IAmLegend'' is one of the few humans that are immune to the disease. He spend the next three years trying to synthesise a cure out of his blood for the humans that instead mutated into the feral Darkstalkers.
** In the Will Smith version he's not the only one, in every other adaptation he is the last uninfected human, ever.