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*In the ''Gensokyo20XX'' series, this is played straight in three instances. The first time is with Keine and, besides the fact it was terminal, the symptoms were only described as "pneumonia and lumps in her lungs". The second time is with Reimu's mother, Reiko, and she passed away of a long term illness, although this is justified in that they didn't know what she has and neither could they diagnose it but it is implied to have had something to do the radioactive fallout. The third time is with Ran and, apparently, it's chronic but not terminal, however, it does leave her with paralysis.
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* In Webcomic/KillLaKillAU, while they are not terminal, although severe, some of the illnesses Ryuuko suffers from are not named and neither are her symptoms described, however, she does tend to get put on life support (she is shown with breathing tubes in her nose and hooked up to an active heart monitor) and is often attached to machines and intravenous drips.

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* In Webcomic/KillLaKillAU, while they are not terminal, although severe, some of the illnesses Ryuuko suffers from are not named and neither are her symptoms described, however, she does tend to get put on life support (she is shown with breathing tubes in her nose and hooked up to an active heart monitor) and is often seen attached to machines and intravenous drips.
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*In Webcomic/KillLaKillAU, while they are not terminal, although severe, some of the illnesses Ryuuko suffers from are not named and neither are her symptoms described, however, she does tend to get put on life support (she is shown with breathing tubes in her nose and hooked up to an active heart monitor) and is often attached to machines and intravenous drips.


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*From Wiki/{{Killerbunnies}}, we have Anwen's condition and not too much information is known about it besides the fact that will eventually kill her, along with it being progressive.
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* ''Anime/VariableGeo'': Satomi's kid brother, Daisuke, suffers from an unspecified medical condition that keeps him bedridden with a hacking cough and, occasionally, seizures. The costs of his treatments are expensive, [[PerpetualPoverty even with Satomi working two full-time jobs.]] Which is why she originally wanted to enter the VG tournament in hopes of winning the prize money and real estate.
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* ''Literature/InfernalDevices'': [[spoiler: Jem's. It was caused by a demon drug that was used to torture him and his parents when he was younger. There is no known cure for it, and he has to keep taking a specific drug to keep on fighting - as Brother Enoch says, taking the drug means a slow death, but keeping him off the drug would mean a quick one.]]

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* ''Literature/InfernalDevices'': ''Literature/TheInfernalDevices'': [[spoiler: Jem's. It was caused by a demon drug that was used to torture him and his parents when he was younger. There is no known cure for it, and he has to keep taking a specific drug to keep on fighting - as Brother Enoch says, taking the drug means a slow death, but keeping him off the drug would mean a quick one.]]
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* Any KeyVisualArts game will have at least one IllGirl that suffers from this, with the exception of ''VisualNovel/{{Planetarian}}'' where the disease is [[spoiler:low battery power with no way to recharge]].

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* Any KeyVisualArts game will have at least one IllGirl that suffers from this, with the exception of ''VisualNovel/{{Planetarian}}'' where the disease is [[spoiler:low battery power with no way to recharge]]. Thus one of the alternate titles for this page, "Key AIDS".
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[[folder:Fanfiction]]
* In Fanfic/TravelsOfTheTrifecta, Paul and Reggie's mother died of an unnamed terminal illness. [[spoiler: Paul learns that he has the same mysterious illness because it's genetic. It seems to have periodic coughing up blood, physical frailty and weakened immune system as general symptoms but it is not stated to be any real-life disease. Given that Pokemon has animals that don't exist in real life, the Pokemon world having its own genetic diseases isn't too unusual.]]
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* This is essentially the fate of [[spoiler: The Mother]] in ''Series/HowIMetYourMother]]. The disease is fatal, and that's pretty much all we know about it.

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* This is essentially the fate of [[spoiler: The Mother]] in ''Series/HowIMetYourMother]].''Series/HowIMetYourMother''. The disease is fatal, and that's pretty much all we know about it.
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* ''Franchise/KagerouProject'': Haruka Kokonose ([[spoiler:Konoha's former self]]) has a rather ambiguous illness, which periodically lands him in hospital for weeks on end due to "attacks", and prevents him from participating in physical activities, implying it's some sort of heart condition. [[spoiler:He dies at 17, after a year-long {{Timeskip}} following his introduction, but his final attack is implied to have been brought on by [=SnakePossessed=]!Kenjirou, so we'll never know how long he would have actually survived on his own]].

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* ''Franchise/KagerouProject'': Haruka Kokonose ([[spoiler:Konoha's former self]]) has a rather ambiguous illness, which periodically illness (although a shot in the ''Konoha's State Of the World'' PV seems to imply it's a heart condition) that lands him in hospital for weeks on end due to "attacks", weeks, and prevents him from participating in physical activities, implying it's some sort of heart condition. activities. [[spoiler:He dies at 17, after a year-long few-months-long {{Timeskip}} following after his introduction, but his final attack is implied to have been brought introduction. However, since it was triggered by the BigBad on by [=SnakePossessed=]!Kenjirou, so purpose, we'll never know how long he would have actually survived lasted on his own]].
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* ''Franchise/KagerouProject'': Haruka Kokonose ([[spoiler:Konoha's former self]]) has a rather ambiguous illness, which periodically lands him in hospital for weeks on end due to "attacks", and prevents him from participating in physical activities, implying it's some sort of heart condition. [[spoiler:He dies at 17, after a year-long {{Timeskip}} following his introduction, but his final attack is implied to have been brought on by [=SnakePossessed=]!Kenjirou, so we'll never know how long he would have actually survived on his own]].
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* ''Series/BuffyTheVampireSlayer'': In the comics, it was retroactively explained that Drusilla was tortured by an "Inquisitor" while in Prague, including the use of a magic torture chair, leaving her in a frail condition. Spike initially hopes the Hellmouth will restore her, but later learns that the blood of her sire (Angel) can cure her affliction.
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* Appears as Drummant's gift in ''Literature/AnnalsOfTheWesternShore''. {{Justified}} because that seems to be the whole ''point'' of the Drum gift, which is called "wasting". The victim just gets weaker and weaker for no apparent reason until they eventually die, which takes about a year. [[spoiler:This is how Melle, Orrec's mother, dies.]]
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* This is essentially the fate of [[spoiler: The Mother]] in ''Series/HowIMetYourMother]]. The disease is fatal, and that's pretty much all we know about it.
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* Trisha from ''FullmetalAlchemist'' died of such a disease. It's never stated what it was but fans consider it either stress-related or cancer.

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* Trisha from ''FullmetalAlchemist'' ''Manga/FullmetalAlchemist'' died of such a disease. It's never stated what it was but fans consider it either stress-related or cancer.
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* Trisha from ''FullmetalAlchemist'' died of such a disease. It's never stated what it was but fans consider it either stress-related or cancer.
* Similarly Tsukimi's deceased mother in ''PrincessJellyfish'' had a vague, deteriorating disease that apparently lasted a few years. Eventually she was hospitalized and died.
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Pulled for being Just A Face And A Caption.


[[quoteright:270:[[{{Webcomic/Homestuck}} http://static.tvtropes.org/pmwiki/pub/images/mituna_fanart_9364.jpg]]]]
[[caption-width-right:270:And that's not even [[ApologizesALot the]] [[AmbiguousDisorder worst]] [[HatesBeingTouched of]] [[MoodSwinger it...]]]]
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many, many brackets :)


[[caption-width-right:270:And that's not even [[ApologizesALot the]] [[AmbiguousDisorder worst]] [[HatesBeingTouched of]] [[MoodSwinger it...]]

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[[caption-width-right:270:And that's not even [[ApologizesALot the]] [[AmbiguousDisorder worst]] [[HatesBeingTouched of]] [[MoodSwinger it...]]
]]]]
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[[quoteright:270:[[{{Webcomic/Homestuck}} http://static.tvtropes.org/pmwiki/pub/images/mituna_fanart_9364.jpg]]]]
[[caption-width-right:270:And that's not even [[ApologizesALot the]] [[AmbiguousDisorder worst]] [[HatesBeingTouched of]] [[MoodSwinger it...]]
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Creator/JMichaelStraczynski has mentioned one riff on this, in which a soap opera writer supposedly put a character into a coma with very specific and carefully-researched symptoms, for a plot that was only supposed to last a couple of episodes... and then realized that if the character's recovery was delayed, he could continue to crank out script after script without ever needing to worry about a pink slip, since nobody else on the writing team knew enough about the disease to write the character's recovery. The actress didn't mind either, since she got a paycheck day after day for a few minutes' laying absolutely still in bed. The producers were somewhat less than pleased at this.[[note]]Rumor has it that a couple of years later, the same writer called the producers asking if they needed his services again; he was told that the producers were still in a coma.[[/note]]

The anime trope of the IllGirl suffers from the same plague of vague. See its page for the full story but the gist of it is the same; some kind of fraility to gain sympathy.

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Creator/JMichaelStraczynski has mentioned one riff on this, in which a soap opera writer supposedly put a character into a coma with very specific and carefully-researched symptoms, for a plot that was only supposed to last a couple of episodes... and then realized that if the character's recovery was delayed, he could continue to crank out script after script without ever needing to worry about a pink slip, since nobody else on the writing team knew enough about the disease to write the character's recovery. The actress didn't mind either, since she got a paycheck day after day for a few minutes' laying lying absolutely still in bed. The producers were somewhat less than pleased at this.[[note]]Rumor has it that a couple of years later, the same writer called the producers asking if they needed his services again; he was told that the producers were still in a coma.[[/note]]

The anime trope of the IllGirl suffers from the same plague of vague. See its page for the full story but the gist of it is the same; some kind of fraility frailty to gain sympathy.
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** Although Alzheimers' Disease, which normally takes years and years to build up, slew Mike Baldwin in a matter of mere ''months'' in ''CoronationStreet''

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** Although Alzheimers' Disease, which normally takes years and years to build up, not only progressed ten times faster than real life, but then slew Mike Baldwin in a matter of mere ''months'' in ''CoronationStreet''
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** Although alzheimers' Disease, which normally takes years and years to build up, slew Mike Baldwin in a matter of mere ''months'' in ''CoroinationStreet''

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** Although alzheimers' Alzheimers' Disease, which normally takes years and years to build up, slew Mike Baldwin in a matter of mere ''months'' in ''CoroinationStreet''''CoronationStreet''
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Mike Baldwin: the quickest ever death from Alzheimers

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** Although alzheimers' Disease, which normally takes years and years to build up, slew Mike Baldwin in a matter of mere ''months'' in ''CoroinationStreet''
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* Any KeyVisualArts game will have at least one IllGirl that suffers from this, with the exception of ''VisualNovel/{{Planetarian}}'' where the disease is [[spoiler:Reverie/Yumemi suffers from low battery power with no way to recharge]].

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* Any KeyVisualArts game will have at least one IllGirl that suffers from this, with the exception of ''VisualNovel/{{Planetarian}}'' where the disease is [[spoiler:Reverie/Yumemi suffers from low [[spoiler:low battery power with no way to recharge]].
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* Any KeyVisualArts game will have at least one IllGirl that suffers from this.

to:

* Any KeyVisualArts game will have at least one IllGirl that suffers from this.this, with the exception of ''VisualNovel/{{Planetarian}}'' where the disease is [[spoiler:Reverie/Yumemi suffers from low battery power with no way to recharge]].
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[[folder:Literature]]
* ''Literature/InfernalDevices'': [[spoiler: Jem's. It was caused by a demon drug that was used to torture him and his parents when he was younger. There is no known cure for it, and he has to keep taking a specific drug to keep on fighting - as Brother Enoch says, taking the drug means a slow death, but keeping him off the drug would mean a quick one.]]
[[/folder]]
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* MadScientist Ghinias Sakhalin in ''MobileSuitGundamThe08thMSTeam'' has some sort of disease that he has to take medication every day for. It mostly looks like paranoid schizophrenia, but he does have some poorly defined physical symptoms as well. The symptoms seem to fit Wilson's Disease, a genetic disorder that prevents the body from metabolizing copper properly whose most common symptoms are brain damage that often presents with schizophrenia-like symptoms and liver disease.
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* The first episode of ''MrShow'' opens with Ronnie Dobbs doing a PSA for his disease "Entitilitus." He notes that no one knows where it comes from or what it is but "entitilitus kills." Toward the end of the episode, when Terry sells the rights to make a {{Biopic}} of Ronnie [[spoiler:after he dies]], movie!Ronnie reveals to movie!Terry that he suffers from entitilitus [[spoiler: [[DiedInYourArmsTonight then dies in his arms]]]].
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--> Her condition was a case of ''terminal moe'', a dangerous illness which crops up in anime whenever they want to make a character more sympathetic through illness but don't want to actually attribute a real illness to them.

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--> -> Her condition was a case of ''terminal moe'', a dangerous illness which crops up in anime whenever they want to make a character more sympathetic through illness but don't want to actually attribute a real illness to them.
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--> Her condition was a case of ''terminal moe'', a dangerous illness which crops up in anime whenever they want to make a character more sympathetic through illness but don't want to actually attribute a real illness to them\\
--''[[http://www.fanfiction.net/u/1263379/gabriel_blessing Gabriel Blessing]] comment on the real illness behind [[{{Sekirei}} Chiho]]'s condition''

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--> Her condition was a case of ''terminal moe'', a dangerous illness which crops up in anime whenever they want to make a character more sympathetic through illness but don't want to actually attribute a real illness to them\\
--''[[http://www.
them.
-->--''[[http://www.
fanfiction.net/u/1263379/gabriel_blessing Gabriel Blessing]] comment on the real illness behind [[{{Sekirei}} Chiho]]'s condition''

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