History Main / OncePerEpisode

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** The fourth case is always [[spoiler:a case of BigGuyFatalitySyndrome, with TheBigGuy accepting their death. The trial ends in a TearJerker and the crime was a NecessaryEvil committed in order to protect everyone (from execution, starvation, or the [[EverybodysDeadDave the truth about the outside world]]]]).

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* ''WebVideo/{{Chubbyemu}}'': "...-emia meaning presence in blood." Bernard will almost always discuss blood condition with this phrase, often when the patient of the episode develops one. It's often thrown into episodes where the patient ''doesn't'' contract a blood condition, such as the "2 liters of fiber supplement" episode mentioning how fiber supplement helps against hypercholestrolemia.

[[folder:Web Comics]]

* ''WebVideo/KentuckyBallistics'' has quite a few {{running gag}}s, but one thing never changes: the tables that the host Scott [=DeShields=] sets up to place his targets are ''always'' destroyed at the end.

* Every Ke$ha song parody by ''The Key of Awesome'', includes Ke$ha's disapproving parents.

* ''WebVideo/UnclearedZeroPointZero'': The dreaded #DGR level ''will'' be among the uncleared levels DGR plays in every episode, no exceptions.

** The fourth case is always [[spoiler:a case of BigGuyFatalitySyndrome, with TheBigGuy accepting their death. The trial ends in a TearJerker and the crime was a NecessaryEvil committed in order to protect everyone (from execution, starvation, or the [[EveryonesDeadDave the truth about the outside world]]]].

** The fourth case is always [[spoiler:a case of BigGuyFatalitySyndrome, with TheBigGuy accepting their death. The trial ends in a TearJerker and the death was committed for a noble cause and protect everyone from [[AwfulTruth the truth about the outside world]]]].

* In every installment of ''VideoGame/DarkSouls'', there is a fight where you have to kill an old hero who has lost his mind, with sad and lowkey music playing.
** In the first installment, it is the final battle against Gwyn, who has lost his mind after burning for thousands of years to prolong the Age of Fire.
** In the second installment, it is Vendrick, the old king of Lothric who contracted the Undead Curse and eventually succumbed to it after being betrayed by his wife.
** In the third installment, it is the battle against the Soul of Cinder. At first the music is rather dramatic, but as it enters phase 2, it becomes a reprise of the music that played in the fight against Gwyn in the first game, as the boss is an amalgamation of every person who has linked the Fire to continue the Age of Fire, starting with Gwyn.

** ''WesternAnimation/SleepingBeauty'': When Aurora hears about her [[DangerousSixteenthBirthday 16th birthday]] from the fairies.

* ''WebVideo/{{Chubbyemu}}'': "...-emia meaning presence in blood." Bernard will almost always discuss blood condition with this phrase, often when the patient of the episode develops a blood condition. It's often thrown into episodes where the patient ''doesn't'' contract a blood condition, such as the "2 liters of fiber supplement" episode mentioning how fiber supplement helps against hypercholestrolemia.

** Every game also has at least one named ally die over the course of the game, with the player having the ability to [[EverythingsDeaderWithZombies bring them back as a zombie later on]], though ''4'' does abandon part of this trend. [[spoiler: No chance of bringing back any of your allies that died when the Earth got destroyed, sadly]]

** Zero is revealed to be [[spoiler:the player]], though what this actually means is different between games [[note]]In 999, the player is young Akane seeing the future through Junpei's perspective, and current Akane is Zero; in ''VLR'', the protagonist Sigma is Zero (though the player is controlling his past self unknowingly inhabiting his future self's body and unaware that his future self is Zero); and in ''ZTD'' the player's viewpoint is that of Zero (Delta) watching the scene through security cameras[[/note]].

* ''Franchise/HomeAlone'':

** Optimus Prime killng an antagonist by going for their face/head.

* In all three ''[[Franchise/GuardiansOfTheGalaxy Guardians of the Galaxy]]'' films, despite acting tough and is one of the more [[{{Jerkass}} jerkish]] Guardians (less so as his CharacterDevelopment goes on), [[Characters/MCURocketRaccoon Rocket]] is the one who sheds [[TenderTears tears of empathy]] for someone in every film of the trilogy:

* Each issue of ''ComicBook/AstroCity'' ends with a street sign reading "You Are Now Leaving Astro City. Please Drive Carefully." Stories that span multiple issues have each one end with a "To Be Continued" sign instead.

* ''ComicBook/{{Diabolik}}'' tends to have TheBigDamnKiss at/near the end of every story, usually a SmoochOfVictory between the titular VillainProtagonist and his lover Eva.
* During Creator/MarkWaid's run on ''Franchise/TheFlash'', every issue started with the lines "I'm Wally West -- the fastest man alive," or some variation thereof. On rare occasion, especially when Wally or a member of his family needs to deliver a speech with emotional punch, other writers still riff on this.
* ''ComicBook/GrooTheWanderer'' has featured many once-an-issue gags in its time, from the fairly subtle 'hidden message' in each issue (usually something helpful such as 'This Is The Hidden Message'), through the ever-changing job titles given to co-writer Mark Evanier (WhatExactlyIsHisJob), to the [[EveryoneChasingYou Everyone Chasing Groo]] ending, complete with SpoofAesop.
* Creator/MattFraction[='s=] ComicBook/{{Hawkeye}} always starts with Clint thinking "Okay, this looks bad" or some variation of it.
* Marvel Comics' Mr. Immortal [[TheyKilledKennyAgain dies]] in all of his appearances.
* Every issue of ''Comicbook/SpiderGirl'' opens with "Your name is May 'Mayday' Parker, and you are the daughter of Spider-Man," or some variation of it.

* In all three ''[[Franchise/GuardiansOfTheGalaxy Guardians of the Galaxy]]'' films, despite acting tough and is one of the more [[{{Jerkass}} jerkish]] Guardians (less so as his CharacterDevelopment goes on), [[Characters/MCURocketRaccoon Rocket]] is the one who sheds [[HumanizingTears tears]] of empathy for someone in every film of the trilogy:

** In all three ''[[Franchise/GuardiansOfTheGalaxy Guardians of the Galaxy]]'' films, despite acting tough and is one of the more jerkish Guardians (less so as his Character Development goes on), [[Characters/MCURocketRaccoon Rocket]] is the one who sheds [[HumanizingTears tears]] of empathy for someone in every film of the trilogy:
*** ''[[Film/GuardiansOfTheGalaxy2014 Vol. 1]]'': When Groot is about to die.
*** ''[[Film/GuardiansOfTheGalaxyVol2 Vol. 2]]'': During Yondu's funeral.
*** ''[[Film/GuardiansOfTheGalaxyVol3 Vol. 3]]'': [[spoiler: When he saves all the baby raccoons and sees all the other animals in the cages]].

** In all three ''Guardians of the Galaxy'' films, despite acting tough and one of the more jerkish Guardians (less so as his Character Development goes on), [[Characters/MCURocketRaccoon Rocket]] is the one who sheds [[HumanizingTears tears]] of empathy for someone in every film of the trilogy:

*** ''[[GuardiansOfTheGalaxyVol2 Vol. 2]]'': During Yondu's funeral.
*** ''[[GuardiansOfTheGalaxyVol3 Vol. 3]]'': [[spoiler: When he saves all the baby raccoons and sees all the other animals in the cages]].

** In all three ''Guardians of the Galaxy'' films, despite acting tough and one of the more jerkish Guardians (less so as his Character Development goes on), [[Rocket]] is the one who sheds [[HumanizingTears tears]] for someone in every film of the trilogy:
''[[Film/GuardiansOfTheGalaxy2014 Vol. 1]]'': When Groot is about to die.
''[[GuardiansOfTheGalaxyVol2 Vol. 2]]'': During Yondu's funeral.
''[[GuardiansOfTheGalaxyVol3 Vol. 3]]'': [[spoiler: When he saves all the baby raccoons and sees all the other animals in the cages]].