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* Elsa in ''Fanfic/BecomingFree'' almost never gets sick due to being AnIcePerson. Most normal viruses and illnesses don't effect her.

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* Elsa in ''Fanfic/BecomingFree'' almost never gets sick due to being AnIcePerson. Most normal viruses and illnesses don't effect her.affect her.
* [[Manga/MyHeroAcademia Izuku Midoriya]] in ''Fanfic/CursedBlood''. In this story, Izuku has a Quirk that manifests in the form of micro-organisms that inhabit his blood. However, it doesn't actually make Izuku immune - the micro-organisms just wipe out any foreign cell or virus entering Izuku's body before it interacts with anything else.
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* Suzu of ''Manga/AyakashiTriangle'' mentions she's never gotten sick, attributing it to her being an ayakashi medium. It's also a bit of joke on her [[IdiotsCannotCatchColds scatterbrained attitude]].

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* Suzu of ''Manga/AyakashiTriangle'' mentions she's never gotten sick, attributing it to her being an ayakashi medium. It's also a bit of joke on her [[IdiotsCannotCatchColds scatterbrained attitude]]. The only time she seemingly gets sick, [[YourMindMakesItReal it's actually just a fit of stress]].
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* [[spoiler:Rosalia Rosellini]] in ''[[VideoGame/TraumaCenter Trauma Team]]'' is miraculously able to exist in perfect symbiosis with a super-virus [[spoiler:and implied MysticalPlague]] that renders her immune to any other form of disease. Unfortunately this applies only to that character, and anyone else who contracts the virus falls victim to a deadly infection with amped-up symptoms of viral hemorrhagic fever (VHF) that kills in a matter of days.
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* [[Franchise/SonicTheHedgehog Shadow the Hedgehog's]] status as the UltimateLifeform isn't solely due to sheer power, it's because he's TheAgeless and has a perfect immune system, and thus biologically immortal. [[spoiler:His creator was aiming for this to save his terminally ill daughter.]]
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[[folder:Anime & Manga]]

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[[folder:Anime & and Manga]]



* Poison Ivy from ''Franchise/{{Batman}}'' is said to be immune to all toxins and diseases, this becomes a plot point in ''Batman: Contagion'' in which Batman asks her help to deliver an experimental cure for the [[ThePlague Ebola Gulf-A]] into a quarantined area.
* The ComicBook/LegionOfSuperHeroes once fought a villain named Immune whose sole superpower was resistance to all forms of disease.
* In ''ComicBook/TeenTitans'' one of the side effects of Beast Boy's powers is that he's incapable of getting sick. This apparently didn't carry over to the cartoon, since one episode had him getting a cold.
* The ''ComicBook/IncredibleHulk'' is immune to pretty much every disease on Earth, including AIDS. This becomes a plot point when his old friend Jim Wilson returns to his life having contracted AIDS, and has to deal with the dilemma whether to give Jim a transfusion of his blood which could save his life, but condemn him to a life much like his. He doesn't go through with it.
* In the ''ComicBook/JudgeDredd'' story "No Future", the four dreaded Dark Judges accidentally ended up in a future Earth populated solely by very technologyically advanced {{Transhuman}}s. Judge Mortis was a bit confused that his [[MakeThemRot rotting touch]] had zero effect on his would-be victim, until the latter explained that their environment protects them from all contagions, including Mortis himself.
* ''ComicBook/{{PS238}}'': [[FlyingBrick F.I.S.S. metahumans]] have superpowered immune systems alongside everything else and are immune to most common forms of sickness. [[spoiler:Even an alien bio-weapon is defeatable in its early stages by a F.I.S.S. blood donation, though a PowerNullifier is needed to keep the blood from killing the patient afterwards]]. Guardian Angel is also immune to disease, but that's because her GuardianEntity prevents all harm from coming to her -- [[spoiler:when the same PowerNullifier is used on her it turns out she has no 'natural' immune system from birth at all and she is killed by a ''Rhinovirus'' infection.]]
* In Marvel Comics - whether it's being an Eternal, a god, a Herald of Galactus, etc. if a character has immortality then a total immunity to disease is also part of the package.
* ''ComicBook/{{Promethea}}'', being a sort of avatar of human imagination, is at one point stated to be "disease-proof."

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* Poison Ivy from ''Franchise/{{Batman}}'' ''ComicBook/{{Batman}}'' is said to be immune to all toxins and diseases, this diseases. This becomes a plot point in ''Batman: Contagion'' Contagion'', in which Batman asks her help to deliver an experimental cure for the [[ThePlague Ebola Gulf-A]] into a quarantined area.
* The ComicBook/LegionOfSuperHeroes once fought fight a villain named Immune whose sole superpower was is resistance to all forms of disease.
* In ''ComicBook/TeenTitans'' ''ComicBook/TeenTitans'', one of the side effects of Beast Boy's powers is that he's incapable of getting sick. This apparently didn't carry over to [[WesternAnimation/TeenTitans2003 the cartoon, cartoon]], since one episode had him getting a cold.
* The ''ComicBook/IncredibleHulk'' ComicBook/TheIncredibleHulk is immune to pretty much every disease on Earth, including AIDS. This becomes a plot point when his old friend Jim Wilson returns to his life having contracted AIDS, and has to deal with the dilemma whether to [[SuperhumanTransfusion give Jim a transfusion of his blood blood]] which could save his life, but condemn him to a life much like his. [[ReedRichardsIsUseless He doesn't go through with it.
it]].
* In the ''ComicBook/JudgeDredd'' story "No Future", the four dreaded Dark Judges accidentally ended end up in a future Earth populated solely by very technologyically technologically advanced {{Transhuman}}s. Judge Mortis was is a bit confused that his [[MakeThemRot rotting touch]] had zero effect on his would-be victim, until the latter explained explains that their environment protects them from all contagions, including Mortis himself.
* ''ComicBook/{{PS238}}'': [[FlyingBrick F.I.S.S. metahumans]] have superpowered immune systems alongside everything else and are immune to most common forms of sickness. [[spoiler:Even an alien bio-weapon is defeatable in its early stages by a F.I.S.S. blood donation, though although a PowerNullifier is needed to keep the blood from killing the patient afterwards]]. afterwards.]] Guardian Angel is also immune to disease, but that's because her GuardianEntity prevents all harm from coming to her -- [[spoiler:when the same PowerNullifier is used on her her, it turns out that she has no 'natural' immune system from birth at all and she is killed by a ''Rhinovirus'' infection.]]
infection]].
* In Marvel Comics - the Franchise/MarvelUniverse, whether it's being an Eternal, [[ComicBook/TheEternals Eternal]], a god, or a Herald of Galactus, etc. [[Characters/MarvelComicsGalactus Galactus]], if a character has immortality then a total immunity to disease is also part of the package.
* ''ComicBook/{{Promethea}}'', being a sort of avatar of human imagination, is at one point stated to be "disease-proof.""disease-proof".



* In ''Film/TheManWhoCouldCheatDeath'', Dr. Bonnet explains to Dr. Gerrard that ever since he had the first transplant that granted him eternal youth, he has never been sick, never had a headache or a toothache, or even a blemish on his skin. And so long as he has a transplant every ten years, he never will.

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* In ''Film/TheManWhoCouldCheatDeath'', Dr. Bonnet explains to Dr. Gerrard that ever since he had the first transplant that granted him eternal youth, he has never been sick, never had a headache or a toothache, or even a blemish on his skin. And so So long as he has a transplant every ten years, he never will.



* In the ''Literature/{{Newsflesh}}'' series, a genetically modified virus means people are immune to the common cold and never get cancer. Instead they turn into zombies.
* The vampires of the Literature/BlackDaggerBrotherhood very very rarely have to worry about illness, and never human ones--as Wrath points out 'I couldn't catch anything you might give me' and are immune to cancer (which is handy, because several of them smoke like chimneys!) This also extends to having STDImmunity (lucky for sex-obsessed Rhage!)

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* In the ''Literature/{{Newsflesh}}'' series, a genetically modified virus means people are immune to the common cold and [[CureForCancer never get cancer.cancer]]. Instead they turn into zombies.
* The vampires of the Literature/BlackDaggerBrotherhood very ''Literature/BlackDaggerBrotherhood'' very rarely have to worry about illness, and never human ones--as ones -- as Wrath points out 'I couldn't catch anything you might give me' and are immune to cancer (which is handy, because several of them smoke like chimneys!) chimneys). This also extends to having STDImmunity (lucky (luckily for sex-obsessed Rhage!)Rhage).



* This is one of the superhuman, vaguely-[[OurElvesAreDifferent elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princesses Maegelle and Daenerys-daughters of Jaehaerys I-died of grayscale and what sounds like a flu, Aegon III of consumption, Viserys II of a unknown illness [Which admittedly may have been poison], Daeron II and his two immediate heirs of the Great Spring Sickness, Jaehaerys II-Daenerys' own grandfather-of another unknown illness, and Maester Aemon of pneumonia), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons''.]]

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* This is one of the superhuman, vaguely-[[OurElvesAreDifferent elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princesses Maegelle and Daenerys-daughters Daenerys -- daughters of Jaehaerys I-died I -- died of grayscale and what sounds like a flu, Aegon III of consumption, Viserys II of a unknown illness [Which illness[[note]]which admittedly may have been poison], poison[[/note]], Daeron II and his two immediate heirs of the Great Spring Sickness, Jaehaerys II-Daenerys' II -- Daenerys' own grandfather-of grandfather -- of another unknown illness, and Maester Aemon of pneumonia), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons''.]]Dragons'']].



* In ''Literature/{{Emergence}}'', hominems are immune to any infectious disease that humans can contract. However, they are not immune to food poisoning, as one hominem learns while also learning he's actually a hominem (he'd always thought he was human).
* ''Literature/{{City of Bones|1995}}'' by Creator/MarthaWells: Krismen are bio-engineered to be highly resistant to the venom of various desert creatures, as well as immune to heatstroke and most diseases that afflict humans—and also can't be affected by [[spoiler: Wardens' soul reading or the Inhabitants' MindRape]]. However, they can contract infection from bad wounds or from forcing foreign objects into their pouch.
* ''Literature/{{Warbreaker}}'': Holding Breath strengthens the immune system, so that [[TheSoulless Drabs]] are more vulnerable to disease while those with several hundred Breaths on up are essentially immune to sickness. [[spoiler: This ends up screwing Vivenna over when she has to temporarily give up her stockpile of Breath, and suddenly comes down with multiple diseases that Breath was holding at bay.]]

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* In ''Literature/{{Emergence}}'', hominems [[HumanSubspecies hominems]] are immune to any infectious disease that humans can contract. However, they are not immune to food poisoning, as one hominem learns while also learning he's actually a hominem (he'd always thought he was human).
* ''Literature/{{City of Bones|1995}}'' by Creator/MarthaWells: ''Literature/CityOfBones1995'': Krismen are bio-engineered to be highly resistant to the venom of various desert creatures, as well as immune to heatstroke and most diseases that afflict humans—and also can't be affected by [[spoiler: Wardens' [[spoiler:Wardens' soul reading or the Inhabitants' MindRape]]. However, they can contract infection from bad wounds or from forcing foreign objects into their pouch.
* ''Literature/{{Warbreaker}}'': Holding Breath strengthens the immune system, so that system; thus, [[TheSoulless Drabs]] are more vulnerable to disease disease, while those with several hundred Breaths on up are essentially immune to sickness. [[spoiler: This [[spoiler:This ends up screwing Vivenna over when she has to temporarily give up her stockpile of Breath, and suddenly comes down with multiple diseases that Breath was holding at bay.]]



* ''Series/TheOuterLimits1995'' episode "The New Breed" involves prototype nanites developed to make this a reality. Basically, the nanites are designed to move through the body and look for any cellular abnormalities. The damaged or mutated cells would then be restored to their original state. And yes, someone even accused the scientist who developed them of playing God. Unfortunately, a friend of his decides to inject himself with the nanites before they're fully tested. Given the nature of the series, things [[GoneHorriblyWrong go horribly wrong]].

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* ''Series/TheOuterLimits1995'' ''Series/TheOuterLimits1995'': The episode "The "[[Recap/TheOuterLimits1995S1E15TheNewBreed The New Breed" Breed]]" involves prototype nanites [[{{Nanomachines}} nanites]] developed to make this a reality. Basically, the nanites are designed to move through the body and look for any cellular abnormalities. The damaged or mutated cells would then be restored to their original state. And yes, someone even accused accuses the scientist who developed develops them of playing God. Unfortunately, a friend of his decides to inject himself with the nanites before they're fully tested. Given the nature of the series, things [[GoneHorriblyWrong go horribly wrong]].



* A variation with the [[HumanAlien Irathient]] in ''Series/{{Defiance}}''. They are immune to most diseases, but they can still be carriers. This is one of the reasons they are looked down upon by most races, especially since they are inherently distrustful of vaccines.
* Played with in the American version of ''[[Series/TheOfficeUS The Office]]''. Dwight claims that he has never been sick in his life. Jim rightly points out that Dwight shouldn't have any immunities then.
* This was the plot of the 1970s series ''The Immortal''. The protagonist was immune to all known diseases and a lot of people wanted to chase him down and get his blood because of it.

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* A variation with the [[HumanAlien [[HumanAliens Irathient]] in ''Series/{{Defiance}}''. They are immune to most diseases, but they can still be carriers. This is one of the reasons they are looked down upon by most races, especially since they are inherently distrustful of vaccines.
* Played with in the American version of ''[[Series/TheOfficeUS The Office]]''.''Series/TheOfficeUS''. Dwight claims that he has never been sick in his life. Jim rightly points out that Dwight shouldn't have any immunities then.
* This was is the plot of the 1970s series ''The Immortal''. ''Series/TheImmortal''. The protagonist was is immune to all known diseases diseases, and a lot of people wanted want to chase him down and get his blood because of it.



** Anti-Paladins, on the other hand, are immune to the ''effects and symptoms'' of diseases, but they can still be ''infected'' and thus act as ''carriers'' to (deliberately) ''spread'' plagues and diseases to others. A prestige class called "[[NamesToRunAwayFromReallyFast Cancer Mage]]" is designed to [[ExploitedImmunity weaponize a similar immunity]].

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** Anti-Paladins, on the other hand, are immune to the ''effects and symptoms'' of diseases, but they can still be ''infected'' and thus act as ''carriers'' to (deliberately) ([[{{Plaguemaster}} deliberately]]) ''spread'' plagues and diseases to others. A prestige class called "[[NamesToRunAwayFromReallyFast "[[TheTopicOfCancer Cancer Mage]]" is designed to [[ExploitedImmunity weaponize a similar immunity]].



* One option for the "Life Support" power in ''TabletopGame/{{Champions}}'' is Immunity to All Terrestrial Diseases, 5 points. Or you can just buy Immunity to a specific disease, but if you want multiple immunities it's cheaper to just buy the whole thing.

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* One option for the "Life Support" power in ''TabletopGame/{{Champions}}'' is Immunity to All Terrestrial Diseases, 5 points. Or you can just buy Immunity to a specific disease, but if you want multiple immunities immunities, it's cheaper to just buy the whole thing.



--->"They will be untouched by plague or disease, no sickness will blight them."
** Averted by the Death Guard legion and other Plague Marines, who sold themselves to the service of Nurgle, the god of pestilence and decay, after they were infected with a plague (created by Nurgle himself) so virulent even their enhanced immune systems couldn't cope with it and selling their souls was the only way to survive. Similarly, in the novel ''[[Literature/SpaceWolf Ragnar's Claw]]'' a group of Space Wolves is sickened by mere proximity to an Unclean One, a greater daemon of Nurgle.

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--->"They --->''"They will be untouched by plague or disease, disease; no sickness will blight them."
"''
** Averted {{Averted|Trope}} by the Death Guard legion and other Plague Marines, who sold themselves to the service of Nurgle, the [[{{Plaguemaster}} god of pestilence and decay, decay]], after they were infected with a plague (created by Nurgle himself) so virulent even their enhanced immune systems couldn't cope with it and selling their souls was the only way to survive. Similarly, in the novel ''[[Literature/SpaceWolf Ragnar's Claw]]'' Claw]]'', a group of Space Wolves is sickened by mere proximity to an Unclean One, a greater daemon of Nurgle.



* ''TabletopGame/{{GURPS}}'' 3E had the Advantage called Immunity To Disease, which gave complete immunity to all diseases. The Advantage called Immortality included Immunity To Disease.

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* ''TabletopGame/{{GURPS}}'' 3E had has the Advantage called Immunity To to Disease, which gave gives complete immunity to all diseases. The Advantage called Immortality included includes Immunity To to Disease.



* In ''TabletopGame/{{Aberrant}}'', Novas are immune to all baseline (i.e. normal human) diseases. However, some Nova specific diseases have begun to evolve (or been created).
* ''TabletopGame/ChroniclesOfDarkness:'' A number of the game's splats (including [[TabletopGame/WerewolfTheForsaken werewolves]], [[TabletopGame/PrometheanTheCreated Prometheans]], and the fan-made [[TabletopGame/LeviathanTheTempest Leviathans]]) gain their Supernatural Potency as a bonus to resist poison or disease.

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* In ''TabletopGame/{{Aberrant}}'', Novas are immune to all baseline (i.e. normal human) [[{{Muggles}} baseline]] diseases. However, some Nova specific diseases have begun to evolve (or been created).
* ''TabletopGame/ChroniclesOfDarkness:'' ''TabletopGame/ChroniclesOfDarkness'': A number of the game's splats (including [[TabletopGame/WerewolfTheForsaken werewolves]], [[TabletopGame/PrometheanTheCreated Prometheans]], and the fan-made [[TabletopGame/LeviathanTheTempest Leviathans]]) gain their Supernatural Potency as a bonus to resist poison or disease.



** Though it's worth mentioning that, according to the in-game codex, they are not immune to everything "at the same time". Basically, they have clusters of unassigned STEM cells (which can turn into any type of cell possible but haven't) in their bodies even during adulthood. So, when they are faced with life-threatening situations, these cells change to counter that (Krogan use this in Bloodpack by beating Vorcha, making them get thicker skins). If a new disease is introduced, these cells make sure that Vorcha are immune, but the number of these clusters is limited and when they are used up, they can't regrow. In other words, the Vorcha immune to Omega plague would have probably died if exposed to a normal deadly disease.

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** Though However, it's worth mentioning that, according to the in-game codex, they are not immune to everything "at the same time". Basically, they have clusters of unassigned STEM stem cells (which can turn into any type of cell possible but haven't) in their bodies even during adulthood. So, when they are faced with life-threatening situations, these cells change to counter that (Krogan (krogan use this in Bloodpack by beating Vorcha, vorcha, making them get thicker skins). If a new disease is introduced, these cells make sure that Vorcha vorcha are immune, but the number of these clusters is limited and when they are used up, they can't regrow. In other words, the Vorcha vorcha immune to Omega plague would have probably died if exposed to a normal deadly disease.



** The Corprus Disease in ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'' grants the infected immunity to all other diseases--at the cost of major case of insanity and BodyHorror. If the player follows the storyline, however, they will contract Corprus and be healed of its negative effects in short succession--while retaining the nifty perk of perfect immunity to everything.
** In ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]'', being a werewolf likewise makes you immune to all diseases. Also, with enough skills & materials you can enchant an equipment to fully protect you from diseases, or find such items through luck(which is the prerequisite to unlock disease immunity enchantment through destroying it).

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** The Corprus Disease in ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'' grants the infected immunity to all other diseases--at diseases -- at the cost of major case of insanity and BodyHorror. If the player follows the storyline, however, they will contract Corprus and be healed of its negative effects in short succession--while succession -- while retaining the nifty perk of perfect immunity to everything.
** In ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]'', being a werewolf likewise makes you immune to all diseases. Also, with enough skills & materials you can enchant an equipment to fully protect you from diseases, or find such items through luck(which luck (which is the prerequisite to unlock disease immunity enchantment through destroying it).



* VideoGame/CastlevaniaLordsOfShadow2: Being a vampire cursed with CompleteImmortality, Gabriel Belmont/Dracula is naturally immune to all poisons and diseases, such as when he is exposed to a [[SyntheticPlague artificially-engineered virus]] that turns humans into monsters instantly, he is completely unaffected. There are not even ill effects for drinking their corrupted blood.
* According to the unit lore for VideoGame/WarCraft III's Death Knight hero, Paladins are immune to all disease, including the Plague of Undeath that was at the time choking the kingdom of Lordaeron. The terrified common folk became suspicious of the Paladins' seemingly perfect health while wading in so much sickness and death, and shunned and persecuted them, believing that they were actually infected. Some Paladins eventually decided ThenLetMeBeEvil and became Death Knights. Much later in VideoGame/WorldOfWarcraft, a quest line involves a Paladin of the Argent Crusade being infected by the Plague, apparently contradicting this.

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* VideoGame/CastlevaniaLordsOfShadow2: ''VideoGame/CastlevaniaLordsOfShadow2'': Being a vampire cursed with CompleteImmortality, Gabriel Belmont/Dracula is naturally immune to all poisons and diseases, such as when he is exposed to a an [[SyntheticPlague artificially-engineered virus]] that turns humans into monsters instantly, he is completely unaffected. There are not even ill effects for drinking their corrupted blood.
* According to the unit lore for VideoGame/WarCraft III's ''VideoGame/{{Warcraft}} III'''s Death Knight hero, Paladins are immune to all disease, including the Plague of Undeath that was at the time choking the kingdom of Lordaeron. The terrified common folk became suspicious of the Paladins' seemingly perfect health while wading in so much sickness and death, and shunned and persecuted them, believing that they were actually infected. Some Paladins eventually decided ThenLetMeBeEvil and became Death Knights. Much later later, in VideoGame/WorldOfWarcraft, ''VideoGame/WorldOfWarcraft'', a quest line involves a Paladin of the Argent Crusade being infected by the Plague, apparently contradicting this.



[[folder:Web Comics]]
* ''Webcomic/TheOrderOfTheStick'': The Crimson Mantle, an artifact created by the Dark One, god of goblinkind, grants his high priest Redcloak immunity to disease (and extended youth). In the print-only prequel ''Recap/StartOfDarkness'', he is the only one in his party unaffected by a disease created by Lirian, a powerful druid, that blocks all spellcasting abilities. Since he retains his powers, he is able to help Xykon turn into a lich; being undead (and therefore also immune to disease) restores Xykon's spellcasting and allows them to break out of Lirian's captivity.

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[[folder:Web Comics]]
[[folder:Webcomics]]
* ''Webcomic/TheOrderOfTheStick'': The Crimson Mantle, an artifact created by the Dark One, the god of goblinkind, grants his high priest Redcloak immunity to disease (and extended youth). In the print-only prequel ''Recap/StartOfDarkness'', ''[[Recap/TheOrderOfTheStickStartOfDarkness Start of Darkness]]'', he is the only one in his party unaffected by a disease created by Lirian, a powerful druid, that blocks all spellcasting abilities. Since he retains his powers, he is able to help Xykon turn into a lich; being undead (and therefore also immune to disease) restores Xykon's spellcasting and allows them to break out of Lirian's captivity.



* In ''WesternAnimation/XMen'', Wolverine's HealingFactor also grants him quick recovery from almost any disease. This becomes a major plot point in a two-part episode: Bishop and Cable both travel back in time to prevent a bioengineered plague from wiping out mutantkin; the former is trying to prevent the disease entirely to save billions of lives in the near future, the latter is from ''further'' in the future where the virus' effect stabilized aspects of the mutant gene preventing worldwide extinction of both humans and mutants. Cable solves the problem by allowing Wolverine to get infected with the plague. Wolverine recovers in minutes, and his immune system now has antibodies that can be used to manufacture a vaccine for the plague, preventing the deadly epidemic while passing along the beneficial aspects required to preserve Cable's timeline.

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* In ''WesternAnimation/XMen'', ''WesternAnimation/XMenTheAnimatedSeries'', Wolverine's HealingFactor also grants him quick recovery from almost any disease. This becomes a major plot point in a two-part episode: Bishop and Cable both travel back in time to prevent a bioengineered plague from wiping out mutantkin; mutantkind; the former is trying to prevent the disease entirely to save billions of lives in the near future, the latter is from ''further'' in the future where the virus' effect stabilized aspects of the mutant gene preventing worldwide extinction of both humans and mutants. Cable solves the problem by allowing Wolverine to get infected with the plague. Wolverine recovers in minutes, and his immune system now has antibodies that can be used to manufacture a vaccine for the plague, preventing the deadly epidemic while passing along the beneficial aspects required to preserve Cable's timeline.
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In RealLife, diseases are a constant and major threat to survival, even for individuals who lead less adventurous lives. And while the human immune system can perform amazing feats of self-preservation at times, no one is truly safe in the face of new, hitherto unseen virus strains and bacteria mutations (not to mention [[TheTopicOfCancer cancer]]).

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In RealLife, diseases are a constant and major threat to survival, even for individuals who lead less adventurous lives. And while the human immune system can perform amazing feats of self-preservation at times, times and has a knack of being able to counter almost anything you can throw at it, no one is truly safe in the face of new, hitherto unseen virus strains and bacteria mutations (not to mention [[TheTopicOfCancer cancer]]).
cancer]]). After all, with the exception of vaccination and some influence from genetics, you have to get sick to become immune to something in the first place.
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* Dragons in ''Manga/MissKobayashisDragonMaid'' are immune to all diseases, which is good considering that their massive size often makes personal hygiene a hassle. However, this ends up throwing a wrench in Kanna's attempts to pull a CaretakerReversal with Saikawa in her SpinOff.

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* Dragons in ''Manga/MissKobayashisDragonMaid'' are immune to all diseases, which is good considering that their massive size often makes personal hygiene a hassle. However, this ends up throwing a wrench in Kanna's attempts to pull a CaretakerReversal with Saikawa in her SpinOff.SpinOff, and Tohru's lack of reference for the severity of different illnesses in the main series means that [[MinorInjuryOverreaction she runs herself ragged trying to find medicine for Kobayashi when she comes down with a fever]].
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* The ComicBook/{{Legion of Super-Heroes}} once fought a villain named Immune whose sole superpower was resistance to all forms of disease.

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* The ComicBook/{{Legion of Super-Heroes}} ComicBook/LegionOfSuperHeroes once fought a villain named Immune whose sole superpower was resistance to all forms of disease.
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* The Windup people of ''Literature/TheWindupGirl'' all have total disease immunity as part of their [[ComboPlatterPowers suite of genetic alterations]]. This is a huge benefit in dystopian future Earth where genetic engineering gone wild has led to an explosion of man-made diseases.

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* The Windup people of ''Literature/TheWindupGirl'' all have total disease immunity as part of their [[ComboPlatterPowers suite of genetic alterations]]. This is a huge benefit in dystopian future Earth where genetic engineering gone wild has led to an explosion of man-made diseases. The EvilGenius generipper who helped bring about this CrapsackWorld argues it would be better to upgrade humanity as a whole than fight a losing battle against pandemics.
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* This is one of the superhuman, vaguely-[[OurElvesAreDifferent elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princess Maegelle-daughter of Jaehaerys I-died of grayscale, Aegon III of consumption, Viserys II of a unknown illness [Which admittedly may have been poison], Daeron II and his two immediate heirs of the Great Spring Sickness, and Jaehaerys II-Daenerys' own grandfather-of another unknown illness), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons''.]]

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* This is one of the superhuman, vaguely-[[OurElvesAreDifferent elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princess Maegelle-daughter (Princesses Maegelle and Daenerys-daughters of Jaehaerys I-died of grayscale, grayscale and what sounds like a flu, Aegon III of consumption, Viserys II of a unknown illness [Which admittedly may have been poison], Daeron II and his two immediate heirs of the Great Spring Sickness, and Jaehaerys II-Daenerys' own grandfather-of another unknown illness), illness, and Maester Aemon of pneumonia), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons''.]]
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** Some {{Prestige Class}}es gain similar immunities; the Tattooed Monk can pick a TattooOfPower granting immunity to natural diseases (and later, to poison and aging); the Contemplative, a prestige class for divine casters with a stronger rapport with their deity, grant complete immunity to natural and magical diseases with the first level.

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** Some {{Prestige Class}}es gain similar immunities; the Tattooed Monk can pick a TattooOfPower PowerTattoo granting immunity to natural diseases (and later, to poison and aging); the Contemplative, a prestige class for divine casters with a stronger rapport with their deity, grant complete immunity to natural and magical diseases with the first level.



* In ''TabletopGame/Warhammer40000'':

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* In ''TabletopGame/Warhammer40000'':
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* In ''Fanfic/WithAKeyAndAKite'', part of Eliza Schuyler Hamilton’s superpower is that she has a HealingFactor and is immune to infections and diseases. When everyone in her house gets scarlet fever, she doesn't, and drinking at homes with cholera still doesn’t give her any ailments.
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* ''TabletopGame/ChroniclesOfDarkness:'' A number of the game's splats (including [[TabletopGame/LeviathanTheTempest Leviathans]], [[TabletopGame/WerewolfTheForsaken werewolves]], and [[TabletopGame/PrometheanTheCreated Prometheans]]) gain their Supernatural Potency as a bonus to resist poison or disease.

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* ''TabletopGame/ChroniclesOfDarkness:'' A number of the game's splats (including [[TabletopGame/LeviathanTheTempest Leviathans]], [[TabletopGame/WerewolfTheForsaken werewolves]], and [[TabletopGame/PrometheanTheCreated Prometheans]]) Prometheans]], and the fan-made [[TabletopGame/LeviathanTheTempest Leviathans]]) gain their Supernatural Potency as a bonus to resist poison or disease.
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* ''ComicBook/{{Promethea}}'', being a sort of avatar of human imagination, is at one point stated to be "disease-proof."
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* Suzu of ''Manga/AyakashiTriangle'' mentions she's never gotten sick, attributing it to her being an ayakashi medium. It's also a bit of joke on her [[IdiotsCannotCatchColds scatterbrained attitude]].
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* ''TabletopGame/ChroniclesOfDarkness:'' A number of the game's splats (including [[TabletopGame/LeviathanTheTempest Leviathans]], [[TabletopGame/WerewolfTheForsaken werewolves]], and [[TabletopGame/PrometheanTheCreated Prometheans]]) gain their Supernatural Potency as a bonus to resist poison or disease.
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dewicking our elves are better per trs


* The elves in ''Franchise/TolkiensLegendarium'' are [[OurElvesAreBetter utterly unaffected by diseases, along with other nifty talents]].

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* The elves in ''Franchise/TolkiensLegendarium'' are [[OurElvesAreBetter [[OurElvesAreDifferent utterly unaffected by diseases, along with other nifty talents]].



* This is one of the superhuman, vaguely-[[OurElvesAreBetter elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princess Maegelle-daughter of Jaehaerys I-died of grayscale, Aegon III of consumption, Viserys II of a unknown illness [Which admittedly may have been poison], Daeron II and his two immediate heirs of the Great Spring Sickness, and Jaehaerys II-Daenerys' own grandfather-of another unknown illness), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons''.]]

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* This is one of the superhuman, vaguely-[[OurElvesAreBetter vaguely-[[OurElvesAreDifferent elven]] characteristics popularly attributed to [[RoyalBlood the Targaryens]] in ''Literature/ASongOfIceAndFire'', with Daenerys being confident enough of this that she personally tends to people dying of the flux ([[CallARabbitASmeerp i.e. dysentery]]). As to the accuracy of this belief, there are multiple historical cases related in the books of Targaryens getting ill (Princess Maegelle-daughter of Jaehaerys I-died of grayscale, Aegon III of consumption, Viserys II of a unknown illness [Which admittedly may have been poison], Daeron II and his two immediate heirs of the Great Spring Sickness, and Jaehaerys II-Daenerys' own grandfather-of another unknown illness), [[spoiler:and Dany is displaying mysterious symptoms of ''something'' at the end of ''A Dance with Dragons''.]]
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* In Marvel Comics - whether it's being an Eternal, a god, a Herald of Galactus, etc. if a character has immortality then a total immunity to disease is also part of the package.
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* The Windup people of ''Literature/TheWindupGirl'' all have total disease immunity as part of their [[ComboPlatterPowers suite of genetic alterations]]. This is a huge benefit in dystopian future Earth where genetic engineering gone wild has led to an explosion of man-made diseases.
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* ''ComicBook/{{PS238}}'': [[FlyingBrick F.I.S.S. metahumans]] have superpowered immune systems alongside everything else and are immune to most common forms of sickness. [[spoiler:Even an alien bio-weapon is defeatable in its early stages by a F.I.S.S. blood donation, though a PowerNullifier is needed to keep the blood from killing the patient afterwards]]. Guardian Angel is also immune to disease, but that's because her GuardianEntity prevents all harm from coming to her -- [[spoiler:when the same PowerNullifier is used on her it turns out she has no 'natural' immune system from birth at all and she is killed by a ''Rhinovirus'' infection.]]
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* ''Literature/{{Warbreaker}}'': Holding Breath strengthens the immune system, so that [[TheSoulless Drabs]] are more vulnerable to disease while those with several hundred Breaths on up are essentially immune to sickness. [[spoiler: This ends up screwing Vivenna over when she has to temporarily give up her stockpile of Breath, and suddenly comes down with multiple diseases that Breath was holding at bay.]]
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[[folder:Fan Works]]
* Elsa in ''Fanfic/BecomingFree'' almost never gets sick due to being AnIcePerson. Most normal viruses and illnesses don't effect her.
[[/folder]]
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Black Best Friend has been renamed to Token Black Friend, it's unclear whether this is actually an example of that trope.


* The ''ComicBook/IncredibleHulk'' is immune to pretty much every disease on Earth, including AIDS. This becomes a plot point when his old friend [[BlackBestFriend Jim Wilson]] returns to his life having contracted AIDS, and has to deal with the dilemma whether to give Jim a transfusion of his blood which could save his life, but condemn him to a life much like his. [[TearJerker He doesn't go through with it]].

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* The ''ComicBook/IncredibleHulk'' is immune to pretty much every disease on Earth, including AIDS. This becomes a plot point when his old friend [[BlackBestFriend Jim Wilson]] Wilson returns to his life having contracted AIDS, and has to deal with the dilemma whether to give Jim a transfusion of his blood which could save his life, but condemn him to a life much like his. [[TearJerker He doesn't go through with it]].it.

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* Poison Ivy from Franchise/{{Batman}}, is said to be immune to all toxins and diseases, this becomes a plot point in ''Batman: Contagion'' in which Batman asks her help to deliver an experimental cure for the [[ThePlague Ebola Gulf-A]] into a quarantined area.

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* Poison Ivy from Franchise/{{Batman}}, ''Franchise/{{Batman}}'' is said to be immune to all toxins and diseases, this becomes a plot point in ''Batman: Contagion'' in which Batman asks her help to deliver an experimental cure for the [[ThePlague Ebola Gulf-A]] into a quarantined area.



[[folder:Film]]
* In ''Film/TheManWhoCouldCheatDeath'', Dr. Bonnet explains to Dr. Gerrard that ever since he had the first transplant that granted him eternal youth, he has never been sick, never had a headache or a toothache, or even a blemish on his skin. Amd so long as he has a transplant every ten years, he never will.

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[[folder:Film]]
[[folder:Films -- Live-Action]]
* In ''Film/TheManWhoCouldCheatDeath'', Dr. Bonnet explains to Dr. Gerrard that ever since he had the first transplant that granted him eternal youth, he has never been sick, never had a headache or a toothache, or even a blemish on his skin. Amd And so long as he has a transplant every ten years, he never will.



* In ''{{Literature/Doom}}'', Arlene gives Jill a sex ed talk during the LA mission. Afterward, she laments that humanity had beaten [=STDs=], including AIDS, just in time for aliens to wipe out most of the species.

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* In ''{{Literature/Doom}}'', ''Literature/{{Doom}}'', Arlene gives Jill a sex ed talk during the LA mission. Afterward, she laments that humanity had beaten [=STDs=], including AIDS, just in time for aliens to wipe out most of the species.



* Goa'uld hosts in ''Series/StargateSG1'' are immune to diseases thanks to the symbiote's innate HealingFactor (it can also heal diseases that the host has before the Goa'uld is implanted). [[{{Mooks}} Jaffa]], which serve as incubators to Goa'uld larvae, have a lesser version of this immunity and must enter a meditative trance to heal.
** This is actually part of a deal worked out between the [[HumansByAnyOtherName Tau'ri]] and the [[LaResistance Tok'ra]]. Since the Tok'ra require the host's consent before being implanted, Daniel offers sending them hosts from among the terminally ill. The ill would likely agree to become a Tok'ra host in exchange for a cure. Jacob Carter (Sam's father) becomes the first. The Tok'ra symbiote Selmak cures his cancer. In return, Jacob's military experience proves invaluable to the Tok'ra.

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* Goa'uld hosts in ''Series/StargateSG1'' are immune to diseases thanks to the symbiote's innate HealingFactor (it can also heal diseases that the host has before the Goa'uld is implanted). [[{{Mooks}} Jaffa]], which serve as incubators to Goa'uld larvae, have a lesser version of this immunity and must enter a meditative trance to heal.
**
heal. This is actually part of a deal worked out between the [[HumansByAnyOtherName Tau'ri]] and the [[LaResistance Tok'ra]]. Since the Tok'ra require the host's consent before being implanted, Daniel offers sending them hosts from among the terminally ill. The ill would likely agree to become a Tok'ra host in exchange for a cure. Jacob Carter (Sam's father) becomes the first. The Tok'ra symbiote Selmak cures his cancer. In return, Jacob's military experience proves invaluable to the Tok'ra.



* This was the plot of the 1970s series ''The Immortal.'' The protagonist was immune to all known diseases and a lot of people wanted to chase him down and get his blood because of it.

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* This was the plot of the 1970s series ''The Immortal.'' Immortal''. The protagonist was immune to all known diseases and a lot of people wanted to chase him down and get his blood because of it.



** Characters of ThePaladin class are immune to all forms of sickness, thanks to their piety and favor with the gods. Consequentially, if they [[FallenHero Fall]], their immunity to disease is revoked with all the other bonuses.

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** Characters of ThePaladin class of 3[[superscript:rd]] level and higher are immune to all forms of sickness, thanks to their piety and favor with the gods. Consequentially, if they [[FallenHero Fall]], their immunity to disease is revoked with all the other bonuses.



** In 1st Edition, several monster types were immune to disease, such as hollyphants, shades, and werebears.

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** The Monk class gains "Purity of body" at 5[[superscript:th]] level, which gives immunity to natural diseases. This is considered much less interesting than the Paladin power, since natural diseases are easy to heal by any mid-level cleric, and even without access to magic any character with good fortitude saves is likely to recover naturally in a few days. Magical and supernatural diseases, now, tend to be much nastier.
** Some {{Prestige Class}}es gain similar immunities; the Tattooed Monk can pick a TattooOfPower granting immunity to natural diseases (and later, to poison and aging); the Contemplative, a prestige class for divine casters with a stronger rapport with their deity, grant complete immunity to natural and magical diseases with the first level.
** In 1st 1[[superscript:st]] Edition, several monster types were immune to disease, such as hollyphants, shades, and werebears.



* In ''TabletopGame/{{Warhammer 40000}}'':

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* In ''TabletopGame/{{Warhammer 40000}}'':''TabletopGame/Warhammer40000'':



-->"They will be untouched by plague or disease, no sickness will blight them."
** Averted by the Death Guard legion & other Plague Marines, who sold themselves to the service of Nurgle, the god of pestilence and decay, after they were infected with a plague (created by Nurgle himself) so virulent even their enhanced immune systems couldn't cope with it and selling their souls was the only way to survive. Similarly, in the novel ''[[Literature/SpaceWolf Ragnar's Claw]]'' a group of Space Wolves is sickened by mere proximity to an Unclean One, a greater daemon of Nurgle.

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-->"They --->"They will be untouched by plague or disease, no sickness will blight them."
** Averted by the Death Guard legion & and other Plague Marines, who sold themselves to the service of Nurgle, the god of pestilence and decay, after they were infected with a plague (created by Nurgle himself) so virulent even their enhanced immune systems couldn't cope with it and selling their souls was the only way to survive. Similarly, in the novel ''[[Literature/SpaceWolf Ragnar's Claw]]'' a group of Space Wolves is sickened by mere proximity to an Unclean One, a greater daemon of Nurgle.



[[folder:Webcomics]]

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[[folder:Webcomics]][[folder:Web Comics]]



'''Burns:''' ''[[ComicallyMissingThePoint Indestructible…]]''

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'''Burns:''' ''[[ComicallyMissingThePoint Indestructible…]]''Indestructible...]]''
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* In ''Film/TheManWhoCouldCheatDeath'', Dr. Bonnet explains to Dr. Gerrard that ever since he had the first transplant that granted him eternal youth, he has never been sick, never had a headache or a toothache, or even a blemish on his skin. Amd so long as he has a transplant every ten years, he never will.
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* In ''TabletopGame/{{Aberrant}}'', Novas are immune to all baseline (i.e. normal human) diseases. However, some Nova specific diseases have begun to evolve (or been created).
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* This was the plot of the 1970s series ''The Immortal.'' The protagonist was immune to all known diseases and a lot of people wanted to chase him down and get his blood because of it.
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Cross-wicking from City Of Bones 1995

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* ''Literature/{{City of Bones|1995}}'' by Creator/MarthaWells: Krismen are bio-engineered to be highly resistant to the venom of various desert creatures, as well as immune to heatstroke and most diseases that afflict humans—and also can't be affected by [[spoiler: Wardens' soul reading or the Inhabitants' MindRape]]. However, they can contract infection from bad wounds or from forcing foreign objects into their pouch.
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* In ''Literature/{{Emergence}}'', hominems are immune to any infectious disease that humans can contract. However, they are not immune to food poisoning, as one hominem learns while also learning he's actually a hominem (he'd always thought he was human).
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* Archie in ''WesternAnimation/ClassOfTheTitans'' is descended from Achilles. While he lacks his ancestor's invulnerability, he does exhibit this trope, extending to immunity to supernatural plagues like the ones in Pandora's Box.

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