History Main / EvilutionaryBiologist

* ''LightNovel/BoogiepopSeries'': The Towa Organization sees it as its duty to help push humanity forward in its evolution as well as seeking out and destroying the individuals who pose a threat to that goal. Much of the conflict in the series is the direct result of their actions, including the creation of Manticore, a human eating monster cloned from an alien. In the novels it seems that Towa wants to keep the "over-evolved" individuals in check and prevent the evolution of humanity in larger scale -- ironically, they enforce this ideology with Synthetic Humans who have very little difference to the "over-evolved" individuals, except that most of them are absolutely loyal to Towa Organization.

* ''LightNovel/ACertainMagicalIndex'': Creator/AleisterCrowley ([[BeethovenWasAnAlienSpy yes, that one]]) is, in this universe, the founder and leader of [[{{Tomorrowland}} Academy City]], a scientifically advanced city located within Tokyo that is comprised mostly of students. Said students are [[DifferentlyPoweredIndividual espers]] whose studies are mainly focused on the development of PsychicPowers, which they gain through a combination of drug treatment and hypnosis, and the usefulness of which are ranked from [[PowerLevels Levels]] [[WhatKindOfLamePowerIsHeartAnyway 1]] through [[PersonOfMassDestruction 5]]. Every esper is essentially a human guinea pig in a massive citywide experiment conducted by the scientists that run Academy City, who range from the [[ForScience amoral]] to the downright [[MadScientist insane]] (the Kihara family), and Aleister himself [[spoiler: is a former magician who turned his back on magic after growing disillusioned with a world in which humans allowed their destiny to be controlled by the magical "phases" that can affect a person's fortune. It's implied that his ultimate goal for the espers is to use the unique energy they unconsciously emit, known as [[AppliedPhlebotinum AIM fields]], to rid the world of magic, which he believes will direct humanity towards its ideal course in which people are freed from fate and mysticism, and the world is built up from the efforts of individuals rather than that of [[RageAgainstTheHeavens the gods]]]].

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Why the Evilutionary Biologist believes this is necessary varies, as do his methods. Some Evilutionary Biologists simply believe that humanity has erred in its domination of the environment, and thus our very survival as a species is threatened unless they force us to continue evolving. Others see change and so-called improvement as [[ForScience goals in and of themselves]], and resolve to use scientific advancement to cause them. Still others seek to create a new race of [[BioAugmentation biologically superior]] {{transhuman}}s or just the UltimateLifeForm with the power of science, either because they see humans as having outlived their time on the planet or because of a genuine desire to improve the human condition. Some will just be a MakerOfMonsters. They often subscribe to the philosophies of [[TheSocialDarwinist Social Darwinism]] and "[[WellIntentionedExtremist The Ends Justify the Means]]". It's not uncommon for them to [[DarwinistDesire practice what they preach]] and marry someone they see as fit and worthy for them.

Regardless, because of his dedication, the Evilutionary Biologist is willing to break laws, engage in [[PlayingWithSyringes experimental alterations upon other human beings]], and ruin lives for [[UtopiaJustifiesTheMeans the higher goal]]. Their creations are no less exempt; whether they're ReplacementGoldfish, with the CloningBlues, or genetically "programmed" to have [[VillainousLineage evil]], their "children" are doomed to live sad, short, [[TurnedAgainstTheirMasters rebellious]] lives, unless they really ''do'' feel [[TrulySingleParent parental]]. They will never realize that EvilEvolves, and will never be able to identify themselves as the villains.

%%* ''Anime/BlueSubmarineNo6'': EmperorScientist Dr. Zorndyke.
* Dr. Clone from ''Anime/DoraemonNobitasGreatAdventureInTheSouthSeas'' is an evil geneticist expelled from the 22nd Century scientific community who delights in tainting the DNA of living beings into creating horrifying monstrosities, whom are then sold off to the black market in trading mutated animals. He's about to convert Jacks' beloved HeroicDolphin ally into a dolphin-GiantCrab fusion before the heroes intervenes.

* ''Manga/BrynhildrInTheDarkness'': Takachiho, an amateur ''geologist'' who stumbles upon alien corpses and technology while exploring a mine for gold, gets the [[SarcasmMode brilliant idea]] to replace all of humanity with {{Half Human Hybrid}}s using the alien's own FantasticNuke to do it and, with a group of like minded individuals, spends 100 years rounding up ''children'' under the age of ten and having "researchers", at gun point, perform [[PlayingWithSyringes horrific experiments]] indistinguishable from ColdBloodedTorture on them to unlock their "true potential" just to achieve this end. At the start of the story, [[FridgeHorror he's on the cusp of succeeding]].

* ''Anime/MobileSuitGundamSEED'': [[MadScientist Dr. Ulen Hibiki]], although he hadn't really built his views around evolutionary dead-end, still wanted to advance the human race as much as possible ForScience. So, to produce his [[ArtificialHuman Ultimate Coordinator]], he didn't stop before using his own yet unborn (in fact, just conceived) son, [[spoiler:Kira Yamato]], as well as many others, as a guinea pig for his experiments. The fact that he eventually succeeded didn't help him, though, when [[TorchesAndPitchforks he was lynched by an angry mob]].
%%* ''Manga/AstroBoy'' has a lot of run-ins with guys like this. His own father even became one.
%%* In ''Anime/BagiTheMonsterOfMightyNature'', another Creator/OsamuTezuka creation, [[spoiler:Ryo's mother was one of these.]] (this is a zero-context example. Please do not unhide until further context has been added.)
* ''LightNovel/BoogiepopSeries'': The Towa Organization sees it as its duty to help push humanity forward in its evolution as well as seeking out and destroying the individuals who pose a threat to that goal. Much of the conflict in the series is the direct result of their actions, including the creation of Manticore, a human eating monster cloned from an alien. In the novels it seems that Towa wants to keep the "overevolved" individuals in check, and prevent the evolution of humanity in larger scale -- ironically they enforce this ideology with Synthetic Humans who have very little difference to the "overevolved" individuals, except that most of them are absolutely loyal to Towa Organization.
* ''Anime/MagicalGirlLyricalNanohaStrikers'': Dr. Jail Scaglietti, the MadScientist behind [[CloningBlues Project F]] and several other ArtificialHuman related experiments. According to [[SmugSnake Quattro]], his ultimate goal is the completion of biomanipulation technology and the creation of a space to do that. That at least several hundred thousand people would die in the process is acceptable collateral damage.
* ''Anime/MacrossFrontier'': [[spoiler:[[MagnificentBastard Grace O'Connor]], the resident MadScientist]]. In Episode 24 [[spoiler: she]] directly stated that [[spoiler:her main goal is for humanity to become greater than [[{{Precursors}} the Protoculture]]]].
%%* ''Manga/KingOfThorn'': Zeus.
* In ''Manga/{{Naruto}}'', it's Orochimaru's StartOfDarkness: he just wants to learn all the jutsu in the world, and when he realizes he can't in a normal human lifetime, he starts experimenting to put himself above all else. It's more just for his own sake than for the world's, and he's using human guinea pigs left and right.
* In ''Manga/{{Bleach}}'', we have Szayelaporro Granz, the eighth Espada, who is obsessed with reaching [[AGodAmI perfection]].
* ''Manga/SoulEater'': Medusa would count: experimenting on children with black blood and reviving the kishin, thus allowing his madness to spread, in her mind means the same as allowing evolution to take over. Her older sister Arachne started off a example when she 'borrowed' the work of an {{Anthropomorphic Personification}} and combined witch and human souls to create the first [[EquippableAlly Weapons]]. The effects have lasted centuries, with the Weapon forms even changing over time; there are several gun-type Weapons alongside the older swords or polearms.
* ''Manga/ProjectARMS'': Keith White thinks that his pursuit of knowledge leaves him perfectly justified to kill, experiment on, mutate, torture, and otherwise ruin the lives of the human test subjects he works with, most of them children. By the series' end, he has taken to [[AGodAmI declaring himself God]] and insisting that he'll nuke the planet so he can remake it in his image. [[spoiler:The irony is that the sentient alien meteor he was using for this plan, Azreal, only came to Earth because it was drawn to the novelty of human emotions, after spending millions of years alone in space. It helps the protagonists instead, since it doesn't want to be alone.]]
* ''Anime/NeonGenesisEvangelion'': SEELE's goal is to [[spoiler:merge all of humanity and an EldritchAbomination together]] because they feel humanity has otherwise "stagnated" as a species.
* ''Webcomic/OnePunchMan'': Dr. Genus, founder of the "House of Evolution". He creates genetically-spliced monstrosities out of his extreme contempt for regular old human beings. [[spoiler:Witnessing Saitama's unexplainable and completely illogical strength causes him to give up on science and just start selling takoyaki instead.]]
* ''Manga/TokyoGhoul'': Dr. Akihiro Kanou, a MadScientist obsessed with the creation of superior {{Half Human Hybrid}}s. His ghoulization experiments have an incredibly high mortality rate, with over a 1000 people killed in his efforts to create his hybrids. He claims that he's doing it to free humanity from their cage, but considering that he's [[TheSociopath a sociopath]] that readily lies to everyone around him, it's difficult to tell how much of this is true. His study at his old laboratory was filled with "hybrids" he'd created by stitching together preserved insect bodies to create things like "Scorpion-Butterflies".
* ''LightNovel/ACertainMagicalIndex'': Creator/AleisterCrowley ([[BeethovenWasAnAlienSpy yes, that one]]) is, in this universe, the founder and leader of [[{{Tomorrowland}} Academy City]], a scientifically advanced city located within Tokyo that is comprised mostly of students. Said students are [[DifferentlyPoweredIndividual espers]] whose studies are mainly focused on the development of PsychicPowers, which they gain through a combination of drug treatment and hypnosis, and the usefulness of which are ranked from [[PowerLevels Levels]] [[WhatKindOfLamePowerIsHeartAnyway 1]] through [[PersonOfMassDestruction 5]]. Every esper is essentially a human guinea pig in a massive citywide experiment conducted by the scientists that run Academy City, who range from the [[ForScience amoral]] to the downright [[MadScientist insane]] (the Kihara family), and Aleister himself [[spoiler: is a former magician who turned his back on magic after growing disillusioned with a world in which humans allowed their destiny to be controlled by the magical "phases" that can affect a person's fortune. It's implied that his ultimate goal for the espers is to use the unique energy they unconsciously emit, known as [[AppliedPhlebotinum AIM fields]], to rid the world of magic, which he believes will direct humanity towards its ideal course in which people are freed from fate and mysticism, and the world is built up from the efforts of individuals rather than that of [[RageAgainstTheHeavens the gods]]]].

* Creator/MarvelComics is filled with these: Mister Sinister, Phaeder, Maelstrom and also possibly [[Characters/MarvelComicsApocalypse Apocalypse]], depending on how strict a definition of biologist is used.
** ''ComicBook/{{Captain Marvel|MarvelComics}}'': The Supreme Intelligence of the Kree has committed monstrous atrocities against his own people in order to spur their evolutionary development.
** [[Characters/MarvelComicsMagneto Magneto]] also dabbled into this a bit, with his creation of the Mutates, genetically-altered mutant {{Mooks}} created when the normal-variety mutants just weren't cutting it in his [[TheSocialDarwinist Social Darwinist]] army.
** ''ComicBook/MarvelZombies'': [[AdaptationalVillainy Reed Richards]] [[NotBrainwashed doesn't get infected]], but [[spoiler:infects [[ComicBook/FantasticFour his entire team]] with the zombie interdimensional bug]], claiming it's the best course of evolution mankind has been presented with. Being an [[ExpendableAlternateUniverse expendable]] CrapsackWorld, this is just the beginning...
** ''ComicBook/NewWarriors'' once had the team fight a supervillain team called Eugenix, whose goal was to improve the human race by killing or sterilizing everyone who they deemed genetically inferior.
** ''ComicBook/TheUltimates'': Gregory Stark is so good at this, and at so many other things, that he made a clone of [[ComicBook/TheIncredibleHulk Hulk]] with Bruce Banner's intellect, and a clone of Franchise/SpiderMan, just in his free time.
** Predating almost all of these is the High Evolutionary (yeah), who can [[HeelFaceRevolvingDoor sometimes]] come across as actually a rather reasonable person. Unfortunately his AGodAmI delusions of grandeur keep driving him to take the theory of evolution and beat it into submission with a sack of rusty doorknobs in order to make his experiments work.
** Marvel's most notable example is probably Miles Warren, aka the Jackal, an enemy of Franchise/SpiderMan. He had a lot of fun cloning Peter Parkers (and Gwen Stacies). Most of the blame for ComicBook/TheCloneSaga was his.
* ''Comicbook/{{Zenith}}'': Dr. Payne created the second generation superhumans with the explicit intent that they replace humanity. [[spoiler:They did. After a fashion.]]
* Franchise/TheDCU:
** ''ComicBook/InfinityInc'': Dr. Love is a mad obstetrician who created the supervillain team Helix by experimenting on the unborn children of pregnant women under his care.
** ''Comicbook/LegionOfSuperHeroes'': 1000 years from now, [[Characters/BatmanRasAlGhul Ra's Al Ghul]] will plot to crash the Moon into the Earth to force humanity to [[ArtisticLicenseBiology pre-emptively evolve]] to prevent it.

** ''ComicBook/Superboy1994'': Dabney Donovan, one of the co-founders of the cloning project Cadmus, is a MadScientist who feels cloning is the way of the future and humans besides himself are basically worthless. The "Hyper-Tension!" arc gives a horrifying look at what he would become if allowed to experiment to his satisfaction, and it involves "cloning" deceased super-heroes into an obedient army of disturbing mix-and-match people who only vaguely resemble those they were cloned from and taking over the earth.
** ''ComicBook/SupermanDoomsdayHunterPrey'': Bertron, an ancient alien who created the creature Doomsday. He was HoistByHisOwnPetard millions of years ago in the days of prehistoric Krypton, but unfortunately for the rest of the universe "The Ultimate" lives on to this day.
* ''ComicBook/TheFilth'': Spartacus Hughes, or at least he tries to be. His dabblings in this seem less like a plan to change humanity than just a particular twisted way of amusing himself.
* ''ComicBook/TheTransformersMegaseries'': has Jhiaxus, who among other things introduced gender to Cybertron just because he could (never mind that the person he did this to went insane in the process), and CombiningMecha (which was also insane), not to mention [[spoiler:turning an entire planet into a replica Cybertron. It's implied he did this to more than one planet.]] Just because he wanted to accelerate Cybertronian evolution.

%%* In ''FanFic/MegaManRecut'', Otto "Raptor" Moreau is this.

* The villain(s) of ''WesternAnimation/{{Felidae}}'' turn out to be doing this with cats -- Preterius through his [[SanitySlippage increasingly inhumane]] AnimalTesting [[PlayingWithSyringes experiments]] with the aim of creating a HealingFactor-inducing serum, [[spoiler:and Claudandus through his SuperBreedingProgram with the aim of breeding cats back to their original, ferocious form.]]

* ''Franchise/{{Saw}}'': Jigsaw isn't a scientist, but an engineer, which still fits the trope well; instead of participating in scientific experimentation, he uses the applied science of engineering to build {{Death Trap}}s. Similarly, his concerns are social rather than biological or genetic -- he's disgusted with the indolence and sloth he sees surrounding him; without the "will to live", humanity would face extinction. His preferred solution is to force people in {{Deadly Game}}s where they have to mutilate themselves or kill someone else.
* ''Film/{{Prometheus}}'': [[spoiler:Attempting to make something better than humans, David conducts experiments with the Chemical A0-3959X.91–15 mutagen that eventually result in the creation of the Xenomorphs.]]
* ''Film/TheManWithTwoBrains'': Dr. Michael Hfuhruhurr is in many ways one of these; as well as being not-quite-all-there and his developing God-complex, he confidently predicts a day where his research will allow "brilliant minds to live on in the bodies of dumb people" and the like. He's somewhat lacking in the evil department, though, as for all the MadScientist CharacterDevelopment that occurs, he's a bit too decent and moral to actually kill in order to achieve his ends.

** ''Film/AViewToAKill'': Carl Mortner, TheDragon to [[BigBad Max Zorin]], is a Josef Mengele {{expy}} who partook in a SuperBreedingProgram to create {{Super Soldier}}s for the Nazis during World War II. His thinking regarding selective breeding has shades of TheSocialDarwinist, commenting how his principles on horse breeding can be also applied to create the "ideal" human. In fact, he did indeed created a generation of extremely intelligent psychopaths, Zorin being one of them. This isn't surprising, as the real Nazis also believed (and attempted) that.
* ''Film/TheSpirit'': The Octopus is trying to find the secret to immortality and godhood. He actually created the titular hero in one of his experiments when he brought a dead cop back to life. The Octopus' {{Mooks}} are also apparently artificial creations.
* In ''Film/KamenRiderTheFirst'', the organization Shocker's name stands for "Sacred Hegemony Of Cycle Kindred Evolutional Realm."

* ''Film/MurdersInTheRueMorgue'': Dr. Mirakle, the villain. Although insane, his theory of the descent of man from ape ancestors is impressive, given that the film is set 15 years before UsefulNotes/CharlesDarwin published ''On the Origin of Species'' (though it had already been posited before).
* ''Literature/TheIslandOfDoctorMoreau'': The various film adaptations -- ''Film/IslandOfLostSouls'', ''Film/TheIslandOfDrMoreau1977'', ''Film/TheIslandOfDrMoreau1996'' -- make Dr. Moreau into one of these. The original Moreau in the book wasn't trying to improve the species (ours or otherwise), but to refine and explore the limits of his ''unorthodox surgical techniques''.
* ''Film/ManOfSteel'': Faora, one of the villains, delivers a lengthy speech to Superman about how "evolution always wins".

-->'''Erik Lensherr:''' If you're in there, I'd like you to know that I agree with every word you said. We are the future. [[spoiler:But, unfortunately, you killed my mother]].
* ''Film/TheAmazingSpiderMan'': Dr. Connors is driven by a vision of a "world without weakness" in which everyone is equal, the limits of the human body having been overcome through science. While he has traces of the Lizard virus in his system, he comes to the conclusion that his Lizard form is a superior creature devoid of human weaknesses, and that his vision can be made a reality by making everyone like him, even if that means forcing the change upon everyone against their will.
-->'''The Lizard:''' I sought to create a stronger human being, but there's no such thing! Human beings are weak, pathetic, feeble-minded creatures... why be human at all, when we can be so much '''more'''?
* ''Franchise/JurassicPark'': Doctor [[AdaptationalVillainy Henry]] [[MadScientist Wu]] seems to be shaping up to be this in the ongoing ''[[Film/JurassicWorld Jurassic]] [[Film/JurassicWorldFallenKingdom World]]'' trilogy. According to his actor, B.D Wong, the main reason Wu has created such nefarious experiments like the ''Indominus rex'' and the ''Indoraptor'' (both of whom are basically AxCrazy dinosaurian [[BioweaponBeast bioweapons]]) is because he seemingly believes he's truly looking at some sort of bigger picture for our planet.
* ''Film/TheFly1986'': For a stretch, Seth Brundle becomes this. After successfully teleporting himself through space via his telepods, Seth has remarkably enhanced strength, stamina, virility, etc. He believes this to be a wonderful unintentional result of the teleportation process, and that anyone else who uses the teleporter will become a superperson. Thus he starts pressuring his lover Veronica to be teleported -- "And I won't wear you out; we'll be the perfect couple! The Dynamic Duo!" When she objects -- both due to her nervousness about the process ''and'' the stranger changes she's seeing in him, such as odd hairs growing out of a wound on his back, a pronounced SweetTooth, and his less-dorky personality -- he is furious, declares her a coward, and sets out to find "someone who'll keep up with me", leading to a tryst with another woman. Only Veronica's timely arrival at the loft stops him from forcibly teleporting her. Shortly after this he comes to realize what's ''actually'' happening to him -- a fly was in the teleporter when he made his fateful trip and he was genetically fused with it. He is slowly becoming a hideous HalfHumanHybrid of human and insect; all of the "improvements" are a result of this and the [[BodyHorror downside is just beginning to show]]. This realization smashes this trope and his ego to pieces.
* ''Film/TheCarRoadToRevenge'': Talen, the BigBad, believes that he is perfecting humanity and giving it the tools it needs to survive. He secures test subjects through kidnapping and human trafficking, and pays his gang by installing cybernetic upgrades in them.
* ''Film/ResidentEvilFilmSeries'': The Umbrella Corporation has shades of this. They started out as just making biological weapons, but upon discovering the zombies the virus created may have useful properties they began conducting super soldier experiments with the same virus. One of the scientists becomes infected himself, overdoses on the vaccine, and turns into a zombie/human/something else hybrid and declares himself the next evolutionary step.
* In ''Film/TheFreakmaker'', Prof. Nolter believes that creating a race of human/plant hybrids will save the human race by eliminating starvation. He undertakes his research by having TheIgor abduct university students so he can experiment on them.
* In ''Film/ScreamAndScreamAgain'', Dr. Browning is looking to create the race of perfect beings by removing limbs and organs from the undeserving and giving them to the worthy.
* ''Film/IslandOfTheFishmen'': Amanda's father, Professor Ernest Marvin, has been experimenting on the native humans of the island in order to create a race of amphibious humanoid creatures that will replace humanity as the Earth's dominant species once humans go extinct.
* In ''Film/AJollyBadFellow'', Professor Bowles-Otterly is a [[TheSocialDarwinist Social Darwinist]] who advocates the removal of those he considers useless to society. However, he veers into Eviutionary Biologist territory when he also advocates the euthanasia of the insane, the physically deformed, the mentally deficient, etc.
* ''Film/PainkillerJane'': Erfan enhances humans by genetic modification, saying they'll achieve a higher state of evolution in doing so.
* Professor Martin Collingwood in ''Film/TheTitan'' is seeking to genetically transform the volunteer test subjects so they can survive on Titan. His goal is laudatory in that he's trying to save the human race, but when the subjects start dying or going insane he's urged to stop and reevaluate the results. He refuses to do so because right now he has the funding and support for his project and wants to race ahead while he has the chance, even though he admits he has no idea what the end result will be.

* An unusual {{aver|tedTrope}}sion in ''Literature/TheIslandOfDoctorMoreau''. While Moreau does conduct horrific experiments on animals with the intent to [[UpliftedAnimal uplift them]] to human form, he is more concerned with [[MadDoctor perfecting his surgical techniques]] than how the products of his efforts would benefit evolution. He even remarks that he could just as well have turned sheep into llamas as animals into humans; the latter was simply more [[MadArtist artistically satisfying]] to him.
%%* ''Literature/{{Duumvirate}}'': The Operator has devoted his life to being one of these. (this is a zero-context example. Please do not unhide until further context has been added.)
* In ''Literature/OryxAndCrake'', Crake is the consummate Evilutionary Biologist. He designs a new, "perfected" species of human, the Children of Crake, [[spoiler: and decides that humans must be destroyed to make room for them. This plan is [[TheBadGuyWins pretty much entirely successful]]; while the superplague he creates doesn't quite kill ''everyone'', there is [[TheEndOfTheWorldAsWeKnowIt absolutely no hope of human civilization ever coming back]].]]
* ''Literature/EndersShadow'': Dr. Volescu genetically engineers super-intelligent humans [[spoiler:that have super-short lifespans as a side-effect]].
* In ''Literature/TheBeastsOfValhalla'' by George C. Chesbro, Siegmund Loge is a Nobelist (often a bad sign in Chesbro's work), famed for his work on a mathematical tool used to predict whether a species is too far along the road to extinction to be saved. In his unpublished, un-peer-reviewed work, he has come to the conclusion that humanity is a doomed species, and must be forced to mutate into MixAndMatchCritters to give it a chance to try again. Experiments on human subjects who didn't volunteer, check. German background, check; bonus, in that he is a fanatical Music/RichardWagner fan. Looks like Santa Claus and has a [[VillainWithGoodPublicity great public image]], and has awesome talents in attracting black budget funding from governments who don't know he's on other people's payrolls or what his agenda is.
* ''Literature/HumanxCommonwealth'': The Meliorare Society is a group of brilliant scientists and genetic engineers who recklessly violated proscriptions against human eugenics in order to "[[ForScience explore the potential of the human genome]]". They worked by posing as [[{{Masquerade}} fertility specialists]], among other things, with the plan to reclaim the "superior" children once they started manifesting powers and thereby prove themselves to the galaxy. Instead, several of their more grotesque failures came to light and they were outlawed and hunted down. Those not killed outright were subjected to [[LaserGuidedAmnesia selective mindwipe]], and all of the subjects that could be found were either given mercy killings or "altered" to be as normal as possible. The last few remaining Meliorares went into hiding, carrying their dreams of vindication with them. Flinx, the main protagonist, is one of the subjects who slipped through the cracks, mainly by not manifesting his awesome PsychicPowers until much later in his life, and he has several encounters with Meliorare fugitives who attempt to "reclaim" him. This has not ended well for them.
* ''Literature/BeyondThisHorizon'': {{Subverted|Trope}}. The world government genetically engineers everybody for maximum genetic perfection (or, at least, elimination of imperfection), except for a carefully guarded population of "control naturals", and strongly encourages particularly hopeful genetic matches, as between the hero and heroine. The subversion is that this is presented as entirely a good thing. (This society is sometimes described as a "socialist" state but bears more in common with Technocracy. Everybody gets a small annual dividend from the output of the whole global economy as if it were a corporation in which all are stockholders; control naturals get a larger dividend, enough for a livable income, in compensation for their genetic inferiority and inability to compete with the average person.)
* Creator/FrankHerbert:
** In two of the author's fictional settings, the planets Dosadi and [[Franchise/{{Dune}} Salusa Secundus]] are both brutally inhospitable prison worlds created to force the beings left on them to adapt and become stronger. The effect seen is more of a cultural (and physical conditioning) change than evolution, though.
** Also in ''Dune'', there's the Bene Tleilax which created such things as [[VoluntaryShapeshifting Face Dancers]] that later on in the series can become "perfect mimics" by absorbing the memories of the individual they've... replaced.
* ''Literature/BraveNewWorld'': {{Subverted|Trope}}. The World State engineers everyone into [[FantasticCasteSystem five castes]], Alpha through Epsilon, ranked by intelligence. The point is to keep everything exactly the way it is forever; [[EvilLuddite technological progress is restrained for the same reason]]. The Savage asks World Controller Mustapha Mond "If you can get anything you want out of those bottles, why not make everybody an Alpha-double-plus?" Mond says they once tried colonizing an island with nothing but Alphas as an experiment, but it quickly degenerated into civil war; everybody wanted to be boss and nobody wanted to do the scutwork. ''Brave New World'' is especially dystopian in that the lower intelligence of the lower castes is not a natural product of genetic variability or even "evolution" in the usual sense. Instead, they've been deliberately handicapped by the introduction of toxins during gestation and development.

* Cyrus, the main villain of ''Literature/SpaceAssassin'', a cruel despot who travels across the galaxy in his PlanetSpaceship and regularly sends his robotic minions to abduct sentient lifeforms on various planets for him to mutant, transform and dissect to his liking. His lair is filled with mutated minions of his working, the scariest being a six-armed [[FrankensteinsMonster Frankensteinian Monster]] called a "Deity" which is seemingly made by stitching together a dozen differrent life forms.
* ''Literature/SpaceTrilogy'': Professor Weston develops interplanetary travel so humanity and their descendants (whatever they evolve into) could go out into the stars and survive throughout the cosmos. However, Weston doesn't care that this plan may involve wiping out other intelligent life. (In the second book, he abandons this goal in favor of a New Age-y philosophy he dubs "Spiritual Evolution", which has nothing to do with this trope.) The trope is taken further in the third book, where the N.I.C.E. plans to replace all organic life with a machine life.
* ''Literature/TheTurnerDiaries'' by white-supremacist William Luther Pierce (writing as Andrew Macdonald) recounts a racial war that ends with the death of all Jews, nonwhites and "mongrels" -- all of them, everywhere in the world. Most white people also die in the fighting and general disruption; the population of the United States is reduced to 50 million. Only those bearing "especially valuable genes" survive. This fulfills the dream of the "Great One" (Hitler) for an "all-White world." The historical Hitler would at least have allowed the non-whites to live on as slaves. The necessity of this appears to be based on "Cosmotheism," a belief-system that is Pierce's own invention, which is a curious mish-mash of the seemingly incompatible beliefs of racism and panentheism, firmly advocating GoalOrientedEvolution that he claimed would lead white people to the status of God.

* ''Literature/TheChrysalids'': An ironic step-sibling of this trope forms the basis of the novel. In a [[AfterTheEnd post-apocalyptic]] future (the apocalypse is phrased in religious terms by the characters as "The Tribulation", and implied to have been a nuclear disaster or war), a primitive, theocratic society seeks to exterminate all {{mutants}}, whether plant, animal or human. While not [[TheSocialDarwinist Social Darwinists]] or scientists, the members of this culture are nevertheless striving to "restore" the purity of life on Earth, in an effort to get back into God's good graces.
* ''Literature/{{Fingerprints}}'': The doctor who first researched psychic abilities, [[spoiler:Steve Mercer]]. He eventually came to regret his work and tried to undo it, but did ''not'' perform a HeelFaceTurn and remained a WellIntentionedExtremist -- just one with different intentions.
* ''Literature/YoungBond'': In ''Literature/SilverFin'', Lord Randolph Hellebore is obsessed with breeding the perfect soldier and is not above experimenting his brother and son in pursuit of his goal.
* ''Literature/GalacticMilieu'' features Marc Remiliard, whose goal is to accelerate the psychic development of the human race to the same level as [[spoiler:his prochronistic mutant brother Jac a disembodied brain]], he had [[VillainWithGoodPublicity good PR]] and merely told everyone he wanted to let people adopt some cool DesignerBabies.
* ''Literature/TheWheelOfTime'': Aginor, one of the Forsaken, is revealed to have been personally responsible for the creation of all of the BigBad's monstrous {{Mooks}}, having performed [[ThoseWackyNazis Josef Mengele]]-esque experiments on his fellow human beings by the thousandfold.
* ''Literature/GhostWalkers'': Dr. Peter Whitney cruelly experimented on orphan girls by inserting animal DNA and altering their psychic abilities. After it went wrong, he tried again with soldiers. Subverted in that Whitney is a genius and has developed many scientific breakthroughs, but he doesn't really worry about ethics or other people.

* ''Literature/AMacabreMythOfAMothMan'' has no less than three. Vincent Mordein tried to unlock the secrets of the human brain [[spoiler:and ended up sticking a penny-sized chip in Jack Daw's head, giving him the ability to control crows]]. Dr. Wu performed gene-splicing on multiple subjects, including Ozzy and Moth-man. And Dante Eclipse performed experiments on the cult he heads, believing that humanity is inherently flawed and they must transcend their species to survive.

* ''Literature/JacobsLadderTrilogy'': The Builders who created ''Jacob's Ladder'' belonged to a religious cult of Evilutionary Biologists who believed that humanity could only advance by facing constant adversity. They expected and indeed hoped for massive amounts of suffering and death among the crew in order to make the survivors stronger.
* ''Literature/ThisImmortal'': Downplayed. George Emmet is not the villain of the piece, but lives purely [[ForScience for science]] and exhibits a LackOfEmpathy, which causes him to do whatever he thinks would improve a species without considering what the moral implications would be. When, at the end of the book, his wife Ellen is pregnant again, he wants to [[GuineaPigFamily try embryo surgery to create a child capable of breathing underwater]]... Ellen isn't having any of that, though.
* ''Literature/StarshipsMage'': The Eugenicists in the backstory started out by quietly manipulating human lineages on Earth to encourage magic in their families. They later took over the Mars colony and began overtly controlling the population and force-breeding test subjects, triggering a war with Earth.

* ''Literature/StarTrekTheEugenicsWars'': The scientists of Chrysalis are attempting to make a new breed of humanity to inherit the world. They're even developing a special strain of streptococcus that the supermen are immune to so they can clear the way for them.
* ''Literature/JoeLedger'': Cyrus Jakoby in ''Dragon Factory'' plans to purify humanity of all "inferior" races through genetically-modified diseases -- but he also creates a race of perfect slaves to toil for the remaining few. Not surprising since in reality he's [[spoiler:UsefulNotes/JosefMengele himself]].
* ''Literature/CuriosityHouse'': Nicholas Rattigan, the BigBad, was driven insane by the atrocities of World War II and thinks the only way to save humans from dying in such horrific ways again is to induce special abilities that will make them harder to kill, even if it means caging test subjects like animals and risking some not surviving the processes. [[spoiler:The four protagonists learn in the first book they are the few successful results of Rattigan's experiments.]]
* ''Literature/TheGoldenHamsterSaga'': Professor Fleischkopf, the villain of ''Freddy in Peril'', dissects hamsters' brains while they're still alive in order to research the nature of the mind. He hopes to discover the genetic underpinnings of intelligence so he can rid the world of "knuckleheads."

** In AudioPlay/BigFinishDoctorWho, [[AbsoluteXenophobe Rassilon]], Founder of Time Lord Society, tried to prevent any races evolving that could threaten the Time Lords. He seeded other worlds to make sure life like the Time Lords would evolve and imprisoned races in other Universes which are in the dungeons of his Foundry.

* ''Series/OrphanBlack'': Dr. Aldous Leekie. His Neolution movement is all about "self-directed evolution" and he sees no problem in creating human clones or experimenting on them to advance this goal.
* In ''Series/KagakuSentaiDynaman,'' the villains' collective name is the Jashinka -- from ''jashin'' (evil god) and ''shinka'' (evolution). In other words, their name ''actually translates to "Evilution."'' However, their plan to convert humans didn't go so well, so they went the usual mass destruction route.

** Dr. Arik Soong was the more benign flavor of Evilutionary Biologist, who balked at his creations' evil natures. He later switches to machines, and his descendant in ''Series/StarTrekTheNextGeneration'' ends up being just a really innovative scientist (however, even his first creation turns evil).
** Dr. Phlox in "[[Recap/StarTrekEnterpriseS01E13DearDoctor Dear Doctor]]", where he refuses to help the Valakians despite having a cure to the plague that's threatening to wipe out their entire species. Why would the good doctor refuse to help them, you might you ask? Because the Menk, a Neanderthal-like subspecies that lives on the planet, will apparently only reach their [[EvolutionaryLevels evolutionary breakthrough]] once the Valakians are dead. Despite the fact there is absolutely no proof that they will evolve or that the presence of the Valakians is hindering their development in anyway. Particularly baffling, since without the Valakians, the Menk would have died out ''centuries'' ago.
* ''Series/StarTrekDeepSpaceNine'': The Dominion established its rule through this trope. Their stormtroopers are bred from birth to fight and made dependent on drugs to keep them docile. Their emissaries are programmed to believe the Founders (the head honchos) are gods. The Dominion isn't above letting loose a super-plague to punish insurgents, either. [[BlackAndGrayMorality Not that the Federation is above it either]]. However, the Federation [[NoTranshumanismAllowed expressly bans genetic augmentation]], which is a major plot point for one of the characters who was illegally genetically modified as a child. While said character ([[spoiler:Dr. Bashir]]) turned out for the better, many of his other cohorts [[WithGreatPowerComesGreatInsanity weren't so lucky]].
* ''Series/{{Primeval}}'': Helen Cutter is a different kind of Evilutionary Biologist: in her own words, she wants to [[spoiler:save the world, not humanity. She ends up going back to the Pliocene to kill hominids and prevent the human race from ever evolving]].
* On ''Series/{{Heroes}}'', Arthur Petrelli wants to make SuperSerum generally available for this reason.
* ''Series/StargateAtlantis'': Michael eventually becomes one of these, with his plans to create a race of [[HalfHumanHybrid human-Wraith hybrids]] and wipe everyone else out. His first experiments were possibly the most atrocious, with him forcibly implanting people with Iratus bug eggs so he could find out the effect of different levels of DNA from either species, creating some sort of Xenomorph-esque monsters in the process.
* ''Series/MurdochMysteries'': In "[[Recap/MurdochMysteriesS3E8FutureImperfect Future Imperfect]]", Dr. Dryus Alger is a prominent member of the Eugenics Society who is abducting dogs and conducting illegal experiments in his attempts to 'perfect' humanity.
* ''Series/MidsomerMurders'': The mastermind behind the murders in "Master Class" is obsessed with the work of Sir Francis Galton, the developer of eugenics, and particularly his belief that 'imperfections' could be bred out of the human race. He attempts to put this theory into practice with his own family.
* ''Series/LawAndOrderSVU'': In "[[Recap/LawAndOrderSpecialVictimsUnitS7E2Design Design]]" Dr. [=McManus=] is very concerned by what he perceives as a drop in average IQ, so he's paying men with high ones to donate sperm hoping it can be raised. Stabler calls him a Nazi trying to make a {{master race}}. Cragen refers to him as "[[{{Literature/Frankenstein}} Dr. Frankenstein]]". Wong says he's considered brilliant in the genetics field and invented many highly innovative selection techniques, but his eugenicist views are very controversial. However, he seems to abide by medical ethics, though his daughter April (unbeknownst to him) certainly does ''[[MedicalRapeAndImpregnate not]]''.

** Fabius Bile, like most things in the setting, is this trope turned up to eleven. His master race are superpowered versions of the existing {{Super Soldier}}s, with the difference that they're all homicidal megalomaniacs, and he's turned the population of entire planets into shambling mutants with his experiments. Oh, and did we mention that his [[LabcoatOfScienceAndMedicine labcoat]] is [[GenuineHumanHide sewn from human skin]]? His most ambitious project? [[spoiler:To clone the Emperor.]]

** An inversion by Ahriman, who turned the entire Thousand Sons legion (the ones loyal to Tzeentch) into living coffins to STOP the mutations/evolution. Needless to say, he is not well liked, even among the Thousand Sons.
%%* ''TabletopGame/{{GURPS}}'': Dr. Mara Omokage in ''GURPS Bio-Tech'' and ''TabletopGame/TranshumanSpace''.
* ''TabletopGame/{{Rifts}}'' has Dr. Desmond Bradford. He is head of the Lone Star Complex, a Pre-Rifts genetic engineering facility that experimented in intelligent mutant animals. Bradford has created a variety of mutant animal soldiers for the [[TheEmpire Coalition States]], but also secretly performs experiments on humans, attempting to create powerful psychic humans. Note that [[EvenEvilHasStandards even the Coalition]] would pale if they knew what he was up to. Not that Bradford cares; he literally believes [[AGodAmI that he is a god]], and is above such petty things as "morals" or "ethical concerns".
* ''TabletopGame/AirshipPirates'': The backstory involves an Evilutionary Biologist that confined most of humanity to fortified Victorian cities and let the rest of the world get taken over by nature.
* ''TabletopGame/TeenageMutantNinjaTurtlesAndOtherStrangeness'': The game featured Doctor Feral. A wealthy humanitarian scientist of [[LawfulGood Scrupulous]] alignment, the good Doctor spends his time honestly working toward a better future for all of humanity. His list of medical advances is long, he donates his medical expertise to assist in difficult cases, and even paid to send his maid's children to college. Too bad he only thinks [[WhatMeasureIsANonHuman of human life as being sacred]] and can routinely be found [[TheyWouldCutYouUp vivisecting sentient mutant animals]] in his [[SupervillainLair underground lab]] while he works on that human immortality drug he is pretty sure he is close to finishing. In a game where all the characters are [[PlayerCharacter intelligent mutant animals]] he tends to come off as a less than altruistic person.
* ''TabletopGame/SirenTheDrowning'' features Echidna, leader of the Current of Oceanus, who wishes to improve Humanity through her experiences so they will have more chance to survive the upcoming [[TheEndOfTheWorldAsWeKnowIt Deluge]]. Unfortunately, she is completely insane, and does so by turning any human she gets her hands into monstrous non-sapient {{Fish Pe|ople}}rson called a Voldianoi.
* ''TabletopGame/TranshumanSpace'' is a relatively low-key near-ish future SF setting, and so doesn't feature ''very'' many mad scientists. However, genetic engineering is ''quite'' advanced, and some of its practitioners do slip into a tendency to do things just because they ''can.''

* ''VideoGame/BinaryDomain'': Yoji Amada [[spoiler:Junior]]'s goal is to create a new race of androids who will infiltrate civilization and... live, eventually supplanting humanity as a saner dominant species in the long run. Note that he doesn't care about the rest of humanity, but believes that the world is on the brink and his creations will not survive otherwise. [[spoiler:The hollow children's ability to literally interbreed with actual humans to create Hybrids, [[ArtificialHuman purely-biological genetically-modified humans]], is the main shocker.]]

* ''VideoGame/Fallout1'':
** The Master was very much an adherent of Evilutionary tenets in the WellIntentionedExtremist mold (certainly, the backdrop of a [[AfterTheEnd post-nuclear apocalypse]] lent his reasoning some gravitas). The Enclave, the adversary of the sequel ''VideoGame/Fallout2'', [[spoiler:was in fact a kind of inversion of this trope. Being among the last "pure-breed humans" in the world, they were planning to commit genocide of all the various mutated strains of humanity that had cropped up, effectively "turning back the clock" on evolution. It is up for discussion whether one of the optional courses of action towards the end of the game, in which the PlayerCharacter convinces one of the scientists responsible for the plan to turn the [[WeaponOfMassDestruction WMD]] they had intended to use for this upon his fellows instead, is a case of using the Evilutionary argument in a more "benign" context]]. Science characters, after passing a skill check, can [[spoiler:point out that the Master's Super Mutants are entirely sterile and thus doomed to extinction. They're actually ''physically incapable'' of biological evolution]].
** ''VideoGame/FalloutNewVegas'': The ''Old World Blues'' DLC has the Think Tanks, with Dr. Borous in particular being responsible for the [[WickedWasps Cazadores]] and [[MixAndMatchCritters Nightstalkers]] (which he claims are as [[MetaphoricallyTrue docile as they are sterile]]) as well as subjecting his dog Gabe to some pretty terrible experiments (though it's possible to [[MyGodWhatHaveIDone make him feel regret for the latter]]). They're also responsible for a [[FesteringFungus special spore]] that infects living people and have made lobotomized people into psychotic zombies (or Lobotomites), a process that you barely manage to survive due to the bullet in your head from the beginning of the game.

%%* ''VideoGame/HouseOfTheDead'': Curien is one of these, though [[LoveMakesYouEvil he]] [[JumpingOffTheSlipperySlope wasn't]] [[MadScientist always]]. Goldman has the mentality of one of these, but he isn't a scientist, he's a OmnicidalManiac CorruptCorporateExecutive who dabbles in science. (this is a zero-context example. Please do not unhide until further context has been added.)
* ''VideoGame/MetalGearSolid2SonsOfLiberty'''s infamous GainaxEnding had the Colonel [[spoiler:AI]] justifying the Patriots by referring to this with regards to ''cultural'' evolution, considering the Internet to be what disrupted natural selection. (''VideoGame/MetalGearSolid4GunsOfThePatriots'' would reveal that they were probably less than honest about this motivation.)

* ''Franchise/ResidentEvil'': The Umbrella Corporation, makers of such fine biological weapons as [[ZombieApocalypse the T-Virus]] and [[ImplacableMan the Nemesis]].

** Last but not least, there's Wesker's evil plot itself from the same game as above. To put it in his own words, "Natural selection leaves the survivors '''STRONGER''' and '''BETTER'''."

* ''VideoGame/SkeletonKrew'' have it's main villain being [[NamesToRunAwayFromReallyFast Moribund Kadaver]], an evil geneticist and biologist whose experiments caused massive amount of human prisoners to mutate into nightmarish abominations.

-->''"Evolution's in a rut, natural selection at an all time low. Shipping out fresh meat will incite territorial rages again, will strengthen and advance us. Even create new breeds."''
* ''VideoGame/{{Wild ARMs 4}}'': The scientists who ran the White Orphanage took orphaned children and used a variety of cruel methods to attempt to mass-produce artificially evolved humans who could use the eponymous [=ARMs=]. Of all their subjects, only nineteen survived the initial experiments, and only two were not eventually killed or turned into mutated horrors.
* ''VideoGame/WingCommander IV'': The BigBad is [[spoiler:a WellIntentionedExtremist that let his extremism evolve into a Nazi Germany-style pogrom, including developing a nanotech-based bioweapon that kills based on preselected genetic criteria. It kills by altering the celluar RNA of a infected person that doesn't measure up, whose ''own immune system'' attacks them, liquefying their flesh. Slowly. At first it's thought that it's a plague, until the main protagonist finds out the truth behind this, and another weapon that destroys ships by [[MadeOfExplodium somehow]] igniting the atmosphere within, turning spacecraft into impromptu furnaces) during a covert mission to the BigBad's stronghold/spaceship. It doesn't exactly help that the BigBad is a member of the same military that the protagonist is, and is actually higher in rank]]. The purported reason behind all this is that "humanity has gotten weak" without the perpetual warring of the first three games, and needs to be "pruned to be able to face the next adversary". Naturally, the protagonist has to stop this out of moral indignation, and the BigBad is deliberately inciting another war through his use of this stuff.
* ''VideoGame/XKaliber2097'' has Dr. Blast, the scientist who performs Morph experimentations to create legion of mutants and monsters. You battles him in his own research lab, filled with his creations, and Blast even injected himself with his own chemicals to transform into a monster.
* In ''VideoGame/{{Headhunter}}'', the BigBad, unbeknownst to TheDragon, was creating a race of super-humans, the first of which he called... Adam. He was also releasing a virus that would wipe out humanity (himself included) and which Adam was immune to -- any humans left alive would be quickly wiped off the face of the Earth by Adam. Since there was only one creature (so no Eve) made and "he" didn't have any genitalia, it's not very clear how said super-race would have been built.
* In ''VideoGame/IHaveNoMouthAndIMustScream'', Nimdok's story involves him facing the fact that he was a Nazi scientist and Josef Mengele's partner and [[TheAtoner atoning]] for his actions. [[HoistByHisOwnPetard His experiments later come back to bite him]] when AM uses them (for example, a youth serum created via the deaths of countless Jewish children) to torture him and the other remaining humans.
* ''VideoGame/MegaManX'': Quite a few villains follow the robotic version of this, trying to improve the technological advancement of their species beyond what humans made them for. Lumine and Sigma (in the MHX remake) actually mention evolution. In the ''VideoGame/MegaManZX'', both [[spoiler:Serpent]] and much more notably [[spoiler:Master Albert]] fit this trope to a T. In addition, it is possible that [[spoiler:Master Thomas]] is an example of this trope as well. [[spoiler:[[TheStarscream Prometheus]]]] calls out [[spoiler:Albert]] on this point, however, declaring that his grand plan of evolution is nothing but a farce and "epic sham", [[spoiler:and considering Albert's AGodAmI tendencies, he might have something of a point]].
* ''VideoGame/DragonQuestIV'': The primary plot concerns the application of the "Secret of Evolution" to make monsters into more powerful monsters.
* ''Franchise/MassEffect'': Shepard's crew can't go two weeks without tripping over ''some'' hideously immoral experiment. Usually involving [[NGOSuperpower Cerberus]] or [[BigBad the Reapers]] in some manner.
** Mordin is a subversion. "No testing on species capable of calculus. Simple rule. Never broke it." He is, however, willing to engage in ''very'' DirtyBusiness -- like upgrading the [[DepopulationBomb genophage]] -- if he feels it will prevent future casualties. Mordin's loyalty mission involves his disillusioned student Maelon, who is willing to conduct brutal experiments to undo the damage they caused. Maelon admits that what he's doing is monstrous, but is already so disgusted with himself he feels he has nothing to lose. Despite this, [[spoiler:[[TheExtremistWasRight Maelon's research proves vital in the third game in securing a future for the Krogan]]]].
** In ''VideoGame/MassEffect3'', we finally meet Miranda's father, Henry Lawson, a man who [[DesignerBabies creates offspring]] based on [[{{Narcissist}} his own genetic template]] and then discards them when [[YouHaveFailedMe they don't live up to his expectations]]. After going through Sanctuary, where he [[spoiler:lured thousands of people promising shelter, only to turn them into husks]], it's clear that he's even more monstrous than Miranda said he was.
* ''VideoGame/NintendoWars'': Caulder, the Big Bad of ''Advance Wars: Days of Ruin''. Strictly speaking, "evolution" isn't his goal, but he's a MadScientist whose involvement in [[spoiler:cloning]] gets him pretty close to this trope. It turns out that [[spoiler:he is actually a clone who killed the original, then made clones of himself in an attempt to sell a clone army]].
* ''VideoGame/BatmanArkhamAsylum'': The Riddler comes off as shades of this, [[SmugSnake justifying]] his actions by pointing out that if the residents of Gotham weren't so stupid they wouldn't die in his traps.
* ''VideoGame/ShinMegamiTenseiStrangeJourney'': In a sense, this is Mitra's motivation. On encountering humans, he begins experimenting on them to see what they can do without. The problem is that, since demons are made of spirit, he doesn't seem to understand that we need such things as "a functioning brain", "blood", "air", and "skin"...
* ''VideoGame/ChronoTrigger'': If you bring Lucca and/or Robo to the final battle, they reveal that Lavos has the DNA of all living creatures on Earth inside of itself. Then they work out why: Lavos ''caused'' human evolution from primitive cavemen to modern-day humanity. Why? Because it's a PlanetEater, and sentient life is more filling, particularly if it's intelligent.
* ''VideoGame/RWBYGrimmEclipse'': [[BigBad Dr. Merlot]] believes the [[TheHeartless Creatures of Grimm]] to be the ultimate form of evolution and has experimented on them to see how far he can take them to perfection and give them a purpose in life as also explained in his VillainSong "Lusus Naturae".
* ''VideoGame/{{Overwatch}}'': Moira O'Deorain is single-minded in her pursuit of knowledge (when she spawns she says, "Science will reveal the truth"), and she has wound up working with [[NebulousEvilOrganisation Talon]] because the multitude of ethical and moral issues with her experiments have made her such a controversial figure that she can't get work.
* ''VideoGame/TheNewOrderLastDaysOfEurope'' features Trofim Lysenko, the technocratic ruler of Magnitogorsk. A [[HistoricalVillainUpgrade historical person]] known for his pseudoscientific beliefs and ardent support of [[LamarckWasRight Lamarckist]] interpretations that living organisms inherit the acquired traits of their forebears and that plants can acquire desirable traits if they grow under extreme duress, he came to the "realization" that this can apply to humans, too, and to promote the desirable traits is necessary for mankind's benefit. In the abandoned city of Magnitogorsk, Lysenko set up a massive system of "experimental chambers", where kidnapped people are subjected to torture in his futile attempts to confirm those theories and turn prisoners into {{Super Soldier}}s that will help him to liberate the war-torn Russia from Nazi Germans and warlords.

* ''Webcomic/DresdenCodak'': Kim Ross moves towards this trope over the comic's run. Starting with [[TheSingularity a basis in technological transhumanism]], she's been stealing memories from hapless passersbys to help create an AI model to help trigger this event. She tries to allow the time-travelling AI that practically lands in her lap to develop in the present, doing the same thing more quickly, ''despite'' the current evidence that says it'll probably wipe out most of humanity in the process. Currently she's gotten her hands on a mini-version and is uploading her model into it. Oh, and she's the protagonist. At the end of the arc where she encounters the time travelling AI, she has somewhat learned to not take her beliefs to the extreme of misanthropy and human inferiority the way her future self did.
%%* ''Webcomic/SaturdayMorningBreakfastCereal'':
%%** Parodied [[http://www.smbc-comics.com/comics/20081030.gif here]].
%%** And again [[http://www.smbc-comics.com/?db=comics&id=1695#comic here]].
* ''Webcomic/EverydayHeroes'': Parodied. As a ShoutOut to Creator/{{Marvel|Comics}}'s High Evolutionary (mentioned above), two members of the S.A.V.E.U.S. team were created by the Somewhat-Below-Average Evolutionary.

* ''Webcomic/GirlGenius'': Dr. Dmitri Vapnoodle specialized in making monsters for the purpose of "culling the herd." Though of course he was careful to engineer in absolute loyalty to himself so he wouldn't be one of the culled.
* ''Webcomic/{{Magellan}}'': Professor George Lonsdale, (the real) BigBad of [[http://magellanverse.com/comic/altruistic/ "Worst Field Trip Ever"]], truly believes that [[LEGOGenetics splicing animal and human DNA]] is the next big evolutionary leap. But then, he's also clearly shown as experimenting on innocents ([[GuineaPigFamily including his own son]]) ForTheEvulz as much as anything else.
* In ''Webcomic/TheDragonDoctors'', Preston Chang turned himself into the Crax, a species that starts out as parasites until they grow to take control of their hosts and become amorphous blob creatures, and can adapt to practically anything but cold. All so that Chang could become immortal. Kili, the shaman, faces Chang in the spirit world twice, the first time when removing a Crax from a patientl; his spirit is driven off and the parasite defeated. The second time he just shows up and drags her through a bunch of painful memories in an attempt to drive her to surrender her body to him. [[spoiler:Then she realizes that she was talking to a ghost -- the Crax's hyper-fast evolution had determined that Chang's megalomaniacal mind was a weakness and [[http://dragondoctors.dhscomix.com/archives/comic/ch-15-page-26 discarded him]], then evolved into harmless gut flora.]]
* ''Webcomic/{{Narbonic}}'': Many mad scientists fall into this, some to create new life because it's somehow 'better', others because they just can. Helen Narbon, for example, likes gerbils, and one such product, Artie, notes how the gerbil is a much more ecologically sustainable form. [[spoiler:Near the climax of ''Narbonic'', a group of conservative-minded hamsters take this logic to its natural conclusion, seeking to wipe out almost all of humanity.]]

** As well as the other ways in which he's an utterly raving MadScientist, Professor Farnsworth often rants about creating, amongst other things, a "[[Film/BrideOfTheMonster race of atomic supermen]]", which he once actually did in order to win a basketball game.
** ''Futurama'' also had an episode of its ''Franchise/TheTwilightZone'' parody, ''The Scary Door'', which featured one of these. He combined the most evil genes from the world's most evil creatures to form the evilest creature of them all:
--->"[[HumansAreTheRealMonsters It turns out it's man]]."
* ''WesternAnimation/ActionMan2000'': Doctor X was a textbook Evilutionary Biologist obsessed with triggering the [[EvolutionaryLevels next step in human evolution]] by causing all sorts of disasters in the hopes of culling unfit humans and cause beneficial mutations in the survivors.

* ''WesternAnimation/StreetSharks'': Dr. Paradigm starts out like this, as evidenced by his monologue about how great his human test subjects will be post-transformation and sans those silly human morals. He abandons that pretty early and switches to simply taking over the town/world though. This is after getting a taste of his own medicine makes him seven kinds of AxCrazy though.

* ''WesternAnimation/LegionOfSuperheroes'' has Dr. Londo who was responsible for transforming [[GuineaPigFamily Timber Wolf]] into what he is now. It's also heavily implied that he wasn't the only test subject and subtly implied that he was aware of his father's work before he was transformed.
* ''WesternAnimation/ExoSquad'': Dr. Ketzer was a genetic engineer who altered a group of villagers ([[ProfessorGuineaPig and himself]]) in the Amazon to give them plant-like abilities. He also infected [[spoiler:Nara Burns]] with the mutating agent as a ploy to get Marsh to do his dirty work for him.
* ''WesternAnimation/MightyMax'': Dr. Eggbert Zygote's goal is to use his evolution machine to create a perfect race of humans. In practice, he mostly just makes monsters.
* ''WesternAnimation/DexHamiltonAlienEntomologist'': Syrrus's goal is to breed an army of super insects to allow him to take over the galaxy.
* ''WesternAnimation/DinoSquad'': Victor Veloci wants to turn regular animals into prehistoric creatures and return Earth to the rule of the dinosaurs.
* ''WesternAnimation/Ben10'': Doctor Animo is obsessed with advancing the evolution of planet Earth ''[[TheUnfettered by any means necessary]]''.

----
->Oh, can't you see/You've got subpar genes/How the planet aches/From every breath you take.

** ''VideoGame/FalloutNewVegas'': The ''Old World Blues'' DLC has the Think Tanks, with Dr. Borous in particular being responsible for the [[DemonicSpiders Cazadores]] and [[MixAndMatchCritters Nightstalkers]] (which he claims are as [[MetaphoricallyTrue docile as they are sterile]]) as well as subjecting his dog Gabe to some pretty terrible experiments (though it's possible to [[MyGodWhatHaveIDone make him feel regret for the latter]]). They're also responsible for a [[FesteringFungus special spore]] that infects living people and have made lobotomized people into psychotic zombies (or Lobotomites), a process that you barely manage to survive due to the bullet in your head from the beginning of the game.

* ''VideoGame/TombRaider'': Jaqueline Natla wants to use Atlantis' powers to create a predator for humans, thereby giving evolution "a kick in the pants".

* [[Sanji's father]] Vinsmoke Judge from ''Manga/OnePiece''. He rules a kingdom with an iron fist and is very abusive to his son [[spoiler:Sanji]]. [[spoiler:He specializes in CreatingLife and genetically engineering humans at the peak of physical prowess. Not to mention he modified his own children to become SuperSoldier {{Tyke Bombs}}s with the cost of their human emotions and empathy.]]

* ''TabletopGame/{{Rifts}}'' has Dr. Desmond Bradford. He is head of the Lone Star Complex, a Pre-Rifts genetic engineering facility that experimented in intelligent mutant animals. Bradford has created a variety of mutant animal soldiers for the [[TheEmpire Coalition States]], but also secretly performs experiments on humans, attempting to create powerful psychic humans. Note that [[EvenEvilHasStandards even the Coalition]] would pale if they knew what he was up to.

* ''Series/BabylonFive'': Both the Shadows ''and'' the Vorlons attempted to force the evolutionary development of the younger races. Disagreement about the best way to go about this eventually led to all out war.

* In ''Literature/The BeastsOfValhalla'' by George C. Chesbro, Siegmund Loge is a Nobelist (often a bad sign in Chesbro's work), famed for his work on a mathematical tool used to predict whether a species is too far along the road to extinction to be saved. In his unpublished, un-peer-reviewed work, he has come to the conclusion that humanity is a doomed species, and must be forced to mutate into MixAndMatchCritters to give it a chance to try again. Experiments on human subjects who didn't volunteer, check. German background, check; bonus, in that he is a fanatical Music/RichardWagner fan. Looks like Santa Claus and has a [[VillainWithGoodPublicity great public image]], and has awesome talents in attracting black budget funding from governments who don't know he's on other people's payrolls or what his agenda is.

* In ''The Beasts of Valhalla'' by George C. Chesbro, Siegmund Loge is a Nobelist (often a bad sign in Chesbro's work), famed for his work on a mathematical tool used to predict whether a species is too far along the road to extinction to be saved. In his unpublished, un-peer-reviewed work, he has come to the conclusion that humanity is a doomed species, and must be forced to mutate into MixAndMatchCritters to give it a chance to try again. Experiments on human subjects who didn't volunteer, check. German background, check; bonus, in that he is a fanatical Music/RichardWagner fan. Looks like Santa Claus and has a [[VillainWithGoodPublicity great public image]], and has awesome talents in attracting black budget funding from governments who don't know he's on other people's payrolls or what his agenda is.

* ''Literature/TheVorkosiganSaga'': The Cetagandan haut [[FantasticCasteSystem caste]], especially the women, are basically running a very long-term genetic engineering project to turn themselves into TranshumanAliens.

* ''Literature/JoeLedger'': Cyrus Jakoby in ''Dragon Factory'' plans to purify humanity of all "inferior" races through genetically-modified diseases -- but he also creates a race of perfect slaves to toil for the remaining few. Not surprising since in reality he's [[spoiler:[[ThoseWackyNazis Josef Mengele]] himself]].

* ''VideoGame/MetalGearSolid2'''s infamous GainaxEnding had the Colonel [[spoiler:AI]] justifying the Patriots by referring to this with regards to ''cultural'' evolution, considering the Internet to be what disrupted natural selection. (''VideoGame/MetalGearSolid4'' would reveal that they were probably less than honest about this motivation.)

[[folder:Fan Fiction]]

[[folder:Film -- Animation]]

[[folder:Film -- Live-Action]]

* ''Franchise/{{Saw}}'': Jigsaw from the movie franchise is not a scientist, but an engineer, which still fits the trope well: instead of participating in scientific experimentation, he uses the applied science of engineering to build his traps. In a similar variation, his concerns are social rather than biological or genetic -- he is disgusted with the indolence and sloth he sees surrounding him. Without the "Will to Live", humankind faces extinction. His preferred solution is to maim and murder people in interesting ways.

* Professor Martin Collingwood in ''Film/TheTitan'' is seeking to genetically transform the volunteer test subjects so they can survive on Titan. His goal is laudatory in that he's trying to save the human race, but when the subjects start dying or going insane he's urged to stop and reevaluate the experiment. He refuses to do so because right now he has the funding and support for his project and doesn't want to risk stopping it, even though he admits he has no idea what the end result will be.

Whenever an Evilutionary Biologist appears on the scene -- they are the most common form of villainous biologist in many games and SpeculativeFiction media -- be on guard for a ScienceIsBad [[AnAesop aesop]] to rear its ugly head.

Compare DesignerBabies, UpliftedAnimal, SuperBreedingProgram, and {{Transhuman}}.

* ''Webcomic/OnePunchMan'': Dr. Genus, founder of the "House of Evolution". He creates genetically-spliced monstrosities out of his extreme contempt for regular old human beings.

* ''VideoGame/CrashBandicoot'': Drs. Neo Cortex and Nitrus Brio created the Evolvo-Ray[[note]]well, Brio did but Cortex took all the credit[[/note]] that created most of the mutant animals, Crash included.

** ''ComicBook/CaptainMarVell'': The Supreme Intelligence of the Kree has committed monstrous atrocities against his own people in order to spur their evolutionary development.

* ''Film/ResidentEvil'': The Umbrella Corporation has shades of this. They started out as just making biological weapons, but upon discovering the zombies the virus created may have useful properties they began conducting super soldier experiments with the same virus. One of the scientists becomes infected himself, overdoses on the vaccine, and turns into a zombie/human/something else hybrid and declares himself the next evolutionary step.

[[quoteright:348:[[ComicBook/TheLeagueOfExtraordinaryGentlemen https://static.tvtropes.org/pmwiki/pub/images/evilutionarybiologist.jpg]]]]

[[folder:Film -- Live Action]]

** ''VideoGame/FinalFantasyVII'': Professor Hojo embodies every trope associated to Evilutionary Biologists and Mad Scientists. A thoroughly nasty piece of work, he's pretty much responsible for all the tragedies and deaths in the game and its spinoffs.

* In ''Fanfic/ChildOfTheStorm'', [[MadScientist Arnim Zola]] moonlights as this. Worryingly, however, he learned his trade from someone even worse... [[spoiler:Sinister.]]