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* ''Literature/RangersApprentice'' -- "Halt's Peril": At first, taking out a Genovesan assassin in exchange for Halt getting a nick on the arm seems like a good trade. Then Halt starts behaving erratically, and it turns out the crossbow bolt was poisoned, forcing Will to go all over the country tracking down both the surviving assassin (to get more information about the poison) ''and'' a skilled healer, in an effort to save Halt's life.
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* In the first episode of ''[[Anime/JapanSinks Japan Sinks: 2020]]'', Ayumu gets a small cut on her leg as she escapes from the wrecked locker room. She never gets this cut treated, and over the course of the series, we see it get more and more infected until she's ultimately forced to get the leg amputated in the final episode.
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* In the first episode of ''[[Anime/JapanSinks Japan Sinks: 2020]]'', Ayumu gets a small cut on her leg as she escapes from the wrecked locker room. She never gets this cut treated, and over the course of the series, we see it get more and more infected until she's ultimately forced to get the leg amputated in the final episode.
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* In ''Literature/MagicalGirlRaisingProject'', Cranberry dies after being scratched by Tama. The light novel notes that Cranberry's wounds are only superficial and that, had anyone else scratched her, she would have been all right. However, Tama's magic means the slightest abrasion inflicted by her will cause a three-foot wide hole to open up in whatever (or whoever) she scratched, which is precisely what happens to Cranberry whose entire upper body is destroyed as a result.
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* In ''Literature/TheCurseOfChalion'', Royse Teidez gets scratched by a captive leopard while killing it in the (mistaken) belief that it's a focus of the titular Curse. He refuses to have the injury tended, it becomes infected, and Teidez falls into a fever and dies.
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* ''Literature/WorldOfTheFiveGods'': In ''The Curse of Chalion'', Royse Teidez gets scratched by a captive leopard while killing it in the (mistaken) belief that it's a focus of the titular Curse. He refuses to have the injury tended, it becomes infected, and Teidez falls into a fever and dies.
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* ''Literature/TheBrotherbandChronicles'' has Tecumsah take what appears to be a minor injury when a blade grazes her temple in battle. However, head wounds are not to be messed with, and she complains of slight dizziness and then [[DiedInYourArmsTonight dies in Stig's arms]].
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* ''Literature/TheBrotherbandChronicles'' ''Literature/{{Brotherband}}'' has Tecumsah take what appears to be a minor injury when a blade grazes her temple in battle. However, head wounds are not to be messed with, and she complains of slight dizziness and then [[DiedInYourArmsTonight dies in Stig's arms]].
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* ''Film/TheDayAfterTomorrow'': When trying to help a woman escape a trapped taxi, Laura gets a fairly nasty cut on her leg due to something sharp underwater. Turns out the cut [[MajorInjuryUnderreaction she brushes off]] ends up getting infected due to the dirty storm surge water, and without proper treatment, she'd end up dying of blood poisoning.
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* ''Film/TheDayAfterTomorrow'': When trying to help a woman escape a trapped taxi, Laura gets a fairly nasty cut on her leg due to something sharp underwater. Turns out the cut [[MajorInjuryUnderreaction she brushes off]] ends up getting infected due to the dirty storm surge water, and without proper treatment, she'd end up nearly dying of blood poisoning.
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* In ''{{Webcomic/Drowtales}}'' this is what ultimately dooms the legendary warrior Quain'tana. During a duel with Sarv'swati she gets a cut on her cheek that she initially ignores, only for the wound to fester because the blade was coated in some sort of poison (implied to be some sort of fungus since she states only splashing alcohol on it gives her any relief). This means when one of her generals attempts a coup she is weakened, and ultimately succumbs to her injuries after killing the traitorous general.
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* ''Literature/TheBrotherbandChronicles'' has [[spoiler:Tecumsah]] take what appears to be a minor injury when a blade grazes her temple in battle. However, head wounds are not to be messed with, and she complains of slight dizziness and then [[DiedInYourArmsTonight dies in Stig's arms]].
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* ''Literature/TheBrotherbandChronicles'' has [[spoiler:Tecumsah]] Tecumsah take what appears to be a minor injury when a blade grazes her temple in battle. However, head wounds are not to be messed with, and she complains of slight dizziness and then [[DiedInYourArmsTonight dies in Stig's arms]].
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* ''Literature/TheBrotherbandChronicles'' has [[spoiler:Tecumsah]] take what appears to be a minor injury when a blade grazes her temple in battle. However, head wounds are not to be messed with, and she complains of slight dizziness and then [[DiedInYourArmsTonight dies in Stig's arms]].
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* ''Fanfic/{{Dangerverse}}'': Even the slightest scratch from a silver blade will cause a werewolf to essentially burn up from the inside out, their body crumbling into ashes within seconds. Three major werewolf antagonists are dispatched this way.
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* ''TabletopGame/MageTheAwakening'': As physical manifestations of Platonic ideals, Astras have one function that they perform ''perfectly''. One example is a sword that instantly kills anyone it strikes.
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* ''Franchise/{{Gundam}}'': In episode 8 of ''Anime/MobileSuitGundam0083StardustMemory'', South Burning of the Earth Federation gets into a skirmish with Zeon's Cima Garahau, sustaining minor damage to his GM Custom in the process. Unfortunately, said "minor damage" includes sparking wiring and a slowly-leaking fuel cell, which eventually causes the mobile suit to explode without warning while Burning is still inside it -- tragically, [[HisNameIs right before he's able to reveal]] the details of Zeon's [[NukeEm Operation Stardust]] to his EFF comrades.
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* ''Franchise/{{Gundam}}'': In episode 8 of ''Anime/MobileSuitGundam0083StardustMemory'', South Burning of the Earth Federation gets into a skirmish with Zeon's Cima Garahau, sustaining minor damage to his GM Custom in the process. Unfortunately, said "minor damage" includes sparking wiring and a slowly-leaking fuel cell, which eventually causes the mobile suit to explode without warning while Burning is still inside it -- tragically, [[HisNameIs right before he's able to reveal]] the details of Zeon's [[NukeEm Operation Stardust]] Stardust to his EFF comrades.
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* ''LightNovel/MushokuTenseiJoblessReincarnation'': The catalyst for the BadFuture timeline is Roxy getting bitten by a mouse. It just so happens this mouse is infected with Magic Stone Disease, which just so happens to be incurable by any means short of God-tier healing magic, and just so happens to be fatal to women who are pregnant, which Roxy just so happens to be at the time. (The local {{Jerkass God|s}} is manipulating events to ensure that all these "just so happens" happen ''just so''.) To say that Rudeus takes her death poorly would be [[DespairEventHorizon something of an understatement]].
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* ''LightNovel/MushokuTenseiJoblessReincarnation'': ''Literature/MushokuTenseiJoblessReincarnation'': The catalyst for the BadFuture timeline is Roxy getting bitten by a mouse. It just so happens this mouse is infected with Magic Stone Disease, which just so happens to be incurable by any means short of God-tier healing magic, and just so happens to be fatal to women who are pregnant, which Roxy just so happens to be at the time. (The local {{Jerkass God|s}} is manipulating events to ensure that all these "just so happens" happen ''just so''.) To say that Rudeus takes her death poorly would be [[DespairEventHorizon something of an understatement]].
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* ''Series/TheTenthKingdom'': The evil Queen's [[PoisonedWeapons poisoned comb]] kills within seconds from the slightest injury. When she tries to strangle Virginia in their final confrontation, Virginia pulls it from her hair and [[KarmicDeath scratches her cheek with it]], leaving her just enough time for a DyingTruce.
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* ''Series/TheTenthKingdom'': ''Series/The10thKingdom'': The evil Queen's [[PoisonedWeapons poisoned comb]] kills within seconds from the slightest injury. When she tries to strangle Virginia in their final confrontation, Virginia pulls it from her hair and [[KarmicDeath scratches her cheek with it]], leaving her just enough time for a DyingTruce.
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* Khal Drogo in ''Series/GameOfThrones'' suffers much the same fate as his book counterpart -- receiving a shallow cut on the chest that becomes infected, leaving him at death's door, and then being rendered catatonic when the healing ritual is intentionally botched. In this case, however, the chest wound is received not during battle, but during a challenge from one of his own men, and wouldn't have happened at all if Drogo hadn't ''[[HoistByHisOwnPetard cut his own chest with the challenger's knife]]'' in order to make a point about how outclassed the guy was. If Drogo hadn't decided to show off, the plot of the show would have turned out very differently.
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* Khal Drogo in ''Series/GameOfThrones'' suffers much the same fate as his book counterpart -- receiving a shallow cut on the chest that becomes infected, leaving him at death's door, and then being rendered catatonic when the healing ritual is intentionally botched. In this case, however, the chest wound is received not during battle, battle but during a challenge from one of his own men, and the chest wound wouldn't have happened at all if Drogo hadn't ''[[HoistByHisOwnPetard cut his own chest with the challenger's knife]]'' in order to make a point about how outclassed the guy was. If Drogo hadn't decided to show off, the plot of the show would have turned out very differently.
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* During the climactic duel in ''Theatre/{{Hamlet}}'', Hamlet is winning against Laertes but gets slashed by Laertes' blade, which was coated in poison by Claudius to ensure Hamlet's death. Hamlet still manages to [[MutualKill mortally wound Laertes]], kill Claudius, and make a big speech before succumbing to the poison.
* During the climactic duel in ''Theatre/{{Hamlet}}'', Hamlet is winning against Laertes but gets slashed by Laertes' blade, which was coated in poison by Claudius to ensure Hamlet's death. Hamlet still manages to [[MutualKill mortally wound Laertes]], kill Claudius, and make a big speech before succumbing to the poison.
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* During the climactic duel in ''Theatre/{{Hamlet}}'', Hamlet is winning against Laertes but gets slashed by
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* ''VideoGame/BatmanArkhamOrigins'': When Batman encounters Copperhead, she manages to scratch him across the cheek. While a minor scratch, [[PoisonousPerson her fingernails are tipped with poison]] and he soon becomes delirious and starts to hallucinate while fighting to make his way to area where Alfred can drop the antidote. All while likewise fending off Copperhead's attacks.
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* ''VideoGame/BatmanArkhamOrigins'': When Batman encounters Copperhead, she manages to scratch him across the cheek. While a minor scratch, [[PoisonousPerson her fingernails are tipped with poison]] poison]], and he soon becomes delirious and starts to hallucinate while fighting to make his way to an area where Alfred can drop the antidote. All while likewise fending off Copperhead's attacks.
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