History Main / BubbleBoy

* In ''Manga/FullmetalAlchemist'', the original Homunculus [[spoiler:who later became "Father"]] was an amorphous alchemic creation who could not survive outside of a specially-prepared flask. [[spoiler:He then made a new "flask" [[HumanoidAbomination that's essentially a human body]], using the blood of a young slave man that he had befriended and tricked into it.]]

* Ethan Shields, an immunodeficient Stark-Fujikawa scientist in ''ComicBook/Marvel2099 Unlimited'', who was also the armoured superhero Galahad... or at least [[RemoteBody controlled the robot]] from within his protective forcefield.
* ''ComicBook/{{Jinty}}'' had a story called "Girl in a Bubble", which was ExactlyWhatItSaysOnTheTin. In this case, the girl was in the bubble not because of lack of immunity to germs, but because her guardian wanted to study the effects of being cut off from the outside world (although she claimed that the girl had no immune system in order to stop her escaping).
* Guardian Angel's BarrierWarrior powers in ''ComicBook/PS238'' have effectively made her this. Since nothing even temporarily harmful can reach her, she can't be immunized, and since the barrier keeps all disease away from her, she has never developed an immune system. When her barrier is temporarily taken away by a PowerNullifier, [[spoiler: she ends up dying as a result, but another character is able to bring her back]]. After that, her barrier ceases to be so proactive and she becomes [[BlessedWithSuck able]] to catch normal, non-life threatening diseases.

* ''ComicStrip/PearlsBeforeSwine'': Pig's sister Farina lives in a plastic bubble, though not because of her immune system but because she's a germaphobe. Shockingly, though, she's actually let other suitors like ''ComicStrip/{{Dilbert}}'' and ''[[ComicStrip/HagarTheHorrible HAGAR THE HORRIBLE]]'' inside, which drives her lover Rat insane.

* ''Film/TheBoyInThePlasticBubble'', starring Creator/JohnTravolta in the title role. A MadeForTV movie VeryLooselyBasedOnATrueStory (See RealLife). It became the TropeCodifier and the inspiration for most of the works which employ or parody the trope.
* The movie ''Film/BubbleBoy''. [[spoiler:It turned out his immune system recovered several years prior and he no longer ''needed'' the bubble -- [[MunchausenSyndrome it was just a way for his mother to control his life]].]]

* The more obscure and insane ''[[http://www.foywonder.com/current_columns/foy_0406.html Crystal Heart]]''. How insane? It includes a scene where the main character and Tawny Kitaen have "sex" ''by rubbing on either side of a crystal window''. Nuff said.

* Kenny from ''Series/BeingHumanUS''. He is in a fairly large room, so he has some comforts though. However, it is portrayed completely seriously. He comments that what he has is not living, and will walk out of the room when he turns 18. It's perhaps understandable that after figuring out Aidan is a vampire, he tries to convince him to turn him [[spoiler: things go horribly wrong from there.]]

* Though not quite a bubble, a teenage girl on ''Series/{{House}}'' who'd just undergone a heart transplant was confined to her sterile bedroom by her germ-paranoid mother.

* On ''Series/NorthernExposure'' Creator/AnthonyEdwards played a man who had developed severe allergies to artificial materials (basically, to US civilization). His whole house was encased in a bubble. At one point he borrowed a space suit from Maurice (a former astronaut) to go among the townsfolk.
* In the ''Series/{{Scorpion}}'' episode, "Don't Burst My Bubble", Happy went to check up on one of her online friends from her female engineers chat group. When she goes to her house, Happy discovers a tree has fallen on it, and that her friend is a "bubble girl". The episode then revolves around how to save her.
* The ''Series/{{Seinfeld}}'' episode "The Bubble Boy". The Bubble Boy was a bit of a {{Jerkass}} though.

* [[Myth/NorseMythology Baldur,]] in ''VideoGame/GodOfWar2018'', turns out to be one of these. He's blessed with invulnerability to all threats, physical or magical...[[BlessedWithSuck but the blessing utterly detached him from the physical world. He's unable to feel anything, whatsoever, right down to the ground he's standing on or the temperature of a room.]] [[BrokenAce A hundred years of that]] [[WithGreatPowerComesGreatInsanity has broken him]] by the time the game starts.

* In an episode of ''WebAnimation/WeeblAndBob'', a boy in a bubble (named "Bubble Boy") asks if Weebl's clean and if he can use his toilet. However he refuses to come out for fear of "the germs" (that's why he's in the bubble in the first place) and starts urinating in his bubble, and drowns in his own wee.

* ''WesternAnimation/OneHundredAndOneDalmatianStreet'' : In the episode "A Date with Destiny... Dallas and Deja Vu," Dylan is overprotective of the Triple D sisters to such an absurd degree that Dolly claims that he'd bubble wrap everyone if he could. On cue, Dawkins walks in and reveals that Dylan actually commissioned a "Puppy Bubble Wrapper," a gun that shoots bubble wrap balls that trap people inside and bounce them around. Later gets bricked as Dylan uses it to save Dallas and himself from falling to death in a plane stunt, sending him bouncing around the city.

* The ''WesternAnimation/EdEddNEddy'' episode "Cry Ed" revolves around Eddy stealing Jimmy's attention by trying to appear even more pathetic and frail than him. Once Edd is fed up with Eddy's pettiness, he takes to putting Jimmy in an inflated rubber glove. Miraculously, he is now immune to physical harm while in the glove and the Cul De Sac kids get more fun playing with Jimmy than babying Eddy.
* In the ''WesternAnimation/FamilyGuy'' episode "The Father, the Son, and the Holy Fonz", Stewie ends up one of these after a botched baptism makes him sick.

* White Knight of ''WesternAnimation/GeneratorRex'' keeps himself in a sealed room after an accident that cleansed him completely of the nanites that have infected everyone on the planet. Notable in that it's very hard to sympathize with him due to it being willing. And that he's a big jerk. White Knight explains that since he is the only being on the planet not infected with nanites, he is only person who can be fully trusted to not turn into an EVO and turn on his allies. Given his fear of germs, he probably would be quite happy to stay in his clean room even if it didn't give him a position of authority.
* In ''WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius'', when a disease is going around kids of town, Carl is put in a bubble by his father, who apparently [[GenerationXerox endured the same treatment]] for ''fourteen years''. Part of the reason is because of the Sick Patch the title character made; what started out as a ploy to get out of school went out of hand.
* On ''WesternAnimation/KaBlam'', a Sniz and Fondue cartoon had Fondue moving into a sanitized bubble habitat after being freaked out by a documentary on skin parasites Sniz showed him.
* ''WesternAnimation/KimPossible'': In "Mathter and Fervent", Ron gets turned into anti-matter by the episode's villain, and has to remain in a giant hamster ball until he is returned to normal to keep him from destroying things with his touch.
* ''WesternAnimation/TheLoudHouse'': In "Butterfly Effect", Lana becomes one after Lola becomes injured in a freak accident, and decides life's too short to take anymore risks.
* ''WesternAnimation/MyGymPartnersAMonkey'' has this episode where Adam has to be in a bubble because he was thought of having allergies. His animal schoolmates were even jealous about him.

* The main characters of ''WesternAnimation/{{Recess}}'' ended up in one of these when they faked the symptoms of a severe illness (they were aiming for a more minor one but [[TheSmartGuy Gretchen]] messed up).
* ''WesternAnimation/TheSimpsons'' episode "Little Girl in the Big Ten" had Bart in a bubble to prevent others from getting sick after being infected with the contagious "Panda Virus" from being bitten by a Chinese mosquito that was in a Krusty Burger toy.
* ''WesternAnimation/SouthPark''

* ''WesternAnimation/SpongebobSquarepants'':

* In the ''WesternAnimation/WeBareBears'' episode "[[Recap/WeBareBearsS4E30Bubble Bubble]]," Panda becomes this after germaphobia overtakes him.

* The ''WesternAnimation/EdEddNEddy'' episode "Cry Ed" revolves around Eddy stealing Jimmy's attention by trying to appear even more pathetic and frail than him. Once Edd is fed up with Eddy's pettiness, he takes to putting jimmy in an inflated rubber glove. Miraculously, he is now immune to physical harm while in the glove and the Cul De Sac kids get more fun playing with Jimmy than babying Eddy.

* On ''Series/NorthernExposure'' Anthony Edwards played a man who had developed severe allergies to artificial materials (basically, to US civilization). His whole house was encased in a bubble. At one point he borrowed a space suit from Maurice (a former astronaut) to go among the townsfolk.

* Ethan Shields, an immunodeficient Stark-Fujikawa scientist in ''ComicBook/{{Marvel 2099}} Unlimited'', who was also the armoured superhero Galahad... or at least [[RemoteBody controlled the robot]] from within his protective forcefield.

* ''Series/StarTrekTheNextGeneration'' has an episode where the ''Enterprise'' crew found kids in a sterile environment inside an abandoned facility. Subverted in that the kids' altered immune systems killed the surrounding germs, as well as possibly every other life form in that building.

* ''WesternAnimation/SouthPark'' plays with this in "[[Recap/SouthParkS3E12HookedOnMonkeyFonics Hooked on Monkey Fonics]]": Mark Cotswolds, who spent most of his life in homeschool, arrives at South Park Elementary School as this because of his parents' fear about public school. Cartman's first reaction is to ask Mark if he has an incurable disease, while the other boys' reaction is to put him out of the bubble to duct tape him on a bench.

** In "[[Recap/SouthParkS5E3SuperBestFriends Super Best Friends]]", Kyle becomes this as punishment after he attempts to tell Cartman they should leave the Blaintologists.

* ''WesternAnimation/SouthPark'':
** Subverted in "[[Recap/SouthParkS3E12HookedOnMonkeyFonics Hooked on Monkey Fonics]]": Mark Cotswolds, who spent most of his life in homeschool, arrives at South Park Elementary School as this because of his parents' fear about public school.

* ''WesternAnimation/JimmyNeutron'':
** Carl becomes a Bubble Boy when a disease is going around town. Part of the reason is because of the Sick Patch the title character made; what started out as a ploy to get out of school went out of hand.
** Carl's father has also stated that he used to be one.