History DelicateAndSickly / AnimeAndManga

* Three male characters in ''{{Another}}'' have this. Our protagonist Kouichi Sakakibara has pneumothorax ([[http://en.wikipedia.org/wiki/Pneumothorax collapsed lung]]),[[spoiler:and he's hospitalized due to it for almost a month at the start of the story, making him miss his first day at [[NewTransferStudent his new school]] and thus missing several details about what will go on]]; Ikuo Takabayashi has [[HeartTrauma a heart condition]] [[spoiler:[[KilledOffForReal and it takes away his life]]]], and Daisuke Wakui is asthmatic.

** According to WordOfGod, Austria spent some years in a wheelchair. It's not explained ''when'' this happened, but {{fanon}} speculates that it may have taken place either after the dissolution of the Austro-Hungarian Empire or right after WorldWarII.

* Hayate Gekko from ''{{Naruto}}'', who looks pale and sickly and has a huge IncurableCoughOfDeath. [[spoiler: Again, he died, but his illness isn't the cause. [[HeKnowsTooMuch He heard the plans of Orochimaru and the Sunagakure people]] and paid for it.]]

** [[spoiler:Itachi, afflicted with an unspecified illness that gives him BloodFromTheMouth]].

* Kaoru "Kaoru-no-Kimi" Orihara from ''OniisamaE'' was held back a year due to an unspecified illness, and when the story begins she has just returned to Seiran Highschool. As such, she not only [[BerserkButton hates it when people neglect their physical well-being]], but sometimes collapses in fits of pain and needs both rest and painkillers. [[spoiler:What's her ailment? ''Breast cancer'', and she even had to go through a ''mastectomy'' at age 16, which caused her to break up with her then-boyfriend Takehiko (the titular Oniisama), and when she returned, she kept her illness a secret from most of her classmates until the symptoms of a possible relapse were shown towards the end.]] What happens to her varies according to the different continuities: [[spoiler:In both of them she goes to Germany with Takehiko after they rekindle their relationship... but while she lives on and they stay HappilyMarried [[BabiesEverAfter with a child]] in the anime, in the manga Kaoru ''does'' die two years after leaving Japan.]]

** We meet [[ElegantClassicalMusician Hijiri Minase] when he has just ''stopped'' being an IllBoy, having had a cornea transplant to fix his eyesight. [[DealWithTheDevil And then things go]] FromBadToWorse.

* Helen in ''Anime/SonicX'' is a paraplegic. Doesn't stop her from having fun, especially around the much more mobile Sonic.

* Tsubaki Kakyouin aka "Tsubaki-hime" and [[spoiler:Muraki's fiancée]] Ukyou Sakuraiji, both from ''YamiNoMatsuei''. Tsubaki has an extremely weak heart, [[spoiler: which led Muraki and other people to kidnap her OnlyFriend Eileen and then kill her to harvest her heart. When Tsubaki learns about this, [[MindRape she]] [[SplitPersonalityTakeover does not]] [[RoaringRampageOfRevenge take]] [[ICannotSelfTerminate it]] [[KillTheCutie well]].]]

* Subverted with Izumi Curtis from ''Manga/FullMetalAlchemist'': a [[EeriePaleSkinnedBrunette pale]], slender, [[SexyMentor attractive]] IronWoobie with frequent attacks of BloodFromTheMouth. It's sometimes PlayedForLaughs when she coughs up blood on someone who upsets her, she can kick your ass, {{bears|AreBadNews}}' asses, and her [[HugeGuyTinyGirl gigiantic]] [[BigBeautifulMan husband]]'s ass, and it generally need not be said that you [[DontYouDarePityMe shouldn't pity her]], because she's so fierce. Also, [[spoiler:she gets better... though only in the manga and the ''Brotherhood'' series, as in the first anime she passes away in between the events of the GrandFinale and TheMovie.]]

* ''Manga/KatekyoHitmanReborn'': Chrome Dokoro/Nagi will die if Mukuro [[spoiler: or currently Daemon Spade]] isn't giving her illusionary organs to replace the ones that she lost when she was hit by a car.

* In the second season fo ''GetBackers'', one of Ban and Ginji's missions is to get a very rare type of blood (named the "Bombay Blood") for an Ill Girl named Yumiko, who needs an urgent transfusion or she'll die in few days. It turns out that Akabane has a dose of it and they have to fight him and his partner Maguruma. [[spoiler: It's also revealed that Ginji [[TheLostLenore had an Ill Girl friend]] in the Infinite Fortress days and she died due to lack of treatment, so he's [[MyGreatestFailure determined to not fail again]] for Yumiko's sake]]. They get the Bombay Blood, and Yumiko is saved.

* Yuki Miyata from ''{{Moshidora}}''. Her illness is not specified, aside of being a congenital one; her hospitalization requires her best friend Minami to take her place as the local CuteSportsClubManager. [[spoiler: Unfortunately, Yuki does NOT get better.]]

* Three show up in ''HonooNoAlpenRose'': Clara (temporary but plot-important illness [[spoiler: that has her brother rat out Jeudi and lundi to get money for her medicine]]), Marie ([[spoiler: confined to a wheelchair, but starts to walk after befriending Lundi]], and specially [[spoiler: Jeudi's MissingMom Helene (weak heart and almost total blindness after the accident that separated her from Jeudi.)]]

* One of the two reasons why [[HaouAiren Kurumi Akino]] [[PromotionToParent is the main breadwinner]] of the family is that her mother is an ill girl and thus she cannot take a regular job. The other is that Kurumi's father died two years before the story started.
* Asa Shigure from ''{{Shuffle}}'' suffers a mysterious illness that often leaves her bedridden, and starts becoming worse as time passes. [[spoiler: It's not an illness, but PowerIncontinence: her weak half-demon body cannot handle the strong magic inherited from her mother, the demon Ama, but Asa utterly refuses to use said power because Ama suffered ''horribly'' due to them and thus she doesn't want her mother to be sad. Rin has to [[TakeAThirdOption take a VERY risky third option]] to force her release said energy, and almost dies for it.]]

* The title character of ''Binetsu Shoujo'' ([[LampshadeHanging "Feverish Girl"]]), Rina Kisaragi. She had anemia and tends to pass out quite a bit, so she often goes to a local hospital for check-ups.

** Since this is a series about sports, there aren't many boys with bad healths but their "places" are generally taken by characters who have serious [[GameBreakingInjury game breaking injuries]] at some points and cannot plau at full potential, lest their injuries will get worse and put their careers at risk. Some examples of this subversion are: [[spoiler: Wakashimazu]] and specially ''Tsubasa himself'' in the second part of the manga and in ''Shin''; Wakabayashi, [[spoiler: Misaki]] and [[spoiler: the South Korean captain Cha Inchon]] from the ''World Youth Cup'' manga.

** [[spoiler:Itachi, afflicted ith an unspecified illness that gives him BloodFromTheMouth]].

** A plot point in a later case. [[spoiler: A lady named Hatsune Kamon had a congenital illness named [[http://en.wikipedia.org/wiki/Turner_Syndrome Turner Syndrome]], which only appears in women since it's associated to X chromosomes. It made her look ''extremely'' different from her [[HalfIdenticalTwin half-identical]] [[LongLostSibling long-separated]] twin brother Raita Banba... [[TwinCest the guy]] [[SurpriseIncest she was going to marry]]. Alongside '''several''' other factors, [[DespairEventHorizon this totally broke poor Hatsune's heart and mind]] once she found out, and she ultimately was DrivenToSuicide. [[FromBadToWorse And for even worse]], Raita was mitakenly accused of killing her, and Conan/Kogoro had to work hard to get him free.]]

** A plot point in a later case. [[spoiler: A woman named Hatsune Kamon had a congenital illness named [[http://en.wikipedia.org/wiki/Turner_Syndrome Turner Syndrome]], which only appears in women since it's associated to X chromosomes. It made her look ''extremely'' different from her [[HalfIdenticalTwin half-identical]] [[LongLostSibling long-separated]] twin brother Raita Banba... [[SurpriseIncest the guy she was going to marry]]. Alongside '''several''' other factors, [[DespairEventHorizon this totally broke Hatsune's mind]] once she found out, and she ultimately was DrivenToSuicide. [[FromBadToWorse And for even worse]], Raita was accused of killing her, and Conan/Kogoro had to work hard to get him free.]]

* ''Manga/DetectiveConan''

* In the MagicKaito special ''Tears of Love for the Black Knight'' (based on a story from the fourth manga volume), FBI agent Jack Connelly's son Kenta is one of these, and he needs surgery to get better. [[spoiler: His father is so desperate to get enough money [[HealthcareMotivation that he becomes a thief named Nightmare]] so he can gather cash and Kenta can be operated on. At the end of the special Kaito Kid confronts Jack on how not only he's a "newbie" in regards to classy thievery, but on how this whole deal will ''badly'' hurt Kenta if he ever finds out, and attempts to get Jack to quit... [[DownerEnding It ends]] [[TearJerker in tears]].]]

** Since this is a series about sports, there aren't many boys with bad healths but their "places" are generally taken by characters who have serious [[GameBreakingInjury game breaking injuries]]. Some examples of this subversion are [[spoiler: Misaki]] and [[spoiler: Cha Inchon]] from the ''World Youth Cup'' manga.

** Played [[TearJerker heartbreakingly straight]] in the {{filler}}s, with a girl named Kaori whose older brother Todakuro is the ghost writer to a murdered novelist, Daisuke Torakura, who paid for her hospital bills in exchange for the guy's hard work. [[spoiler: We later learn the horrible truth: Kaori actually died a year ago because Torakura actually ''bribed her doctor into keeping her on '''painkillers only''' instead of paying for '''crucial''' and expensive treatment abroad (as per his end of the bargain)'', so Todakuro would remain indefinitely time as his subordinate, which ultimately killed her. Then, Torakura mantained the lie via keeping Todakuro locked in his countryside villa, telling him that Kaori (supposed to be in an American hospital) was going to get better. When poor Todakuro found out the truth from the guilt-ridden nurse who used to tend to Kaori, he went nuts with pain and murdered Torakura. AssholeVictim seems a bit lenient. Basically, Torakura was MovingTheGoalposts.]]
** A plot point in a later case. [[spoiler: A muder victim named Hatsune Kamon had a congenital illness named [[http://en.wikipedia.org/wiki/Turner_Syndrome Turner Syndrome]], which only appears in women since it's associated to sex chromosomes. It made her look ''extremely'' different from her [[HalfIdenticalTwin half-identical]] [[LongLostSibling long-separated]] twin brother Raita Banba... [[SurpriseIncest the guy she was going to marry]]. Alongside ''several'' other factors, [[DespairEventHorizon this totally broke Hatsune's mind]] once she found out, and she ultimately was DrivenToSuicide. Bad thing, Raita was accused of killing her, and Conan/Kogoro had to work hard to get him free.]]

%%%** Hotaru Tomoe
%%%** One-time character Misa-chan from the Stars season.
%%%* Megumi aka Megu, Suigintou's medium and MoralityPet from ''RozenMaiden''.

%%* Usopp's best friend Kaya from ''Manga/OnePiece''. She got better later, though.

* Even in the afterlife, Hisoka Kurosaki from ''YamiNoMatsuei00 encounters side-effects from his empathy (being in large crowds and/or witnessing a particularly gruesome vision) and [[spoiler: curse marks]] (whenever [[spoiler: Muraki]] is nearby). He is also extremely sensitive to the sun and he can't hold his liquor well at all.

** A further subversion is that Yukimura does in fact have a specific illness (Guillain-Barré syndrome, a disease of the nervous syndrome) which led to some fan complaints after [[spoiler:he recovered, [[YouFailYourMedicalBoardsForever because this condition is incurable.]]]]
*** Handwaved in an author's note, apparently: he does ''not'' suffer from Guillain-Barré, but from a similar illness... which is not mentioned.

* Jun Misugi from ''CaptainTsubasa'', forced to withdraw from soccer because he's got a weak heart. [[spoiler: He ''partially'' gets better later. [[HesBack He can play again]] after an operation, but [[FragileSpeedster is frequently plagued by stamina problems]] and takes [[TheStrategist a strategist and Smart Guy role]] instead.]]

* Tsubaki Kakyouin aka "Tsubaki-hime" and [[spoiler:Muraki's fiancée]] Ukyou Sakuraiji, both from ''YamiNoMatsuei''. Tsubaki has an extremely weak heart, [[spoier: which led Muraki and other people to kidnap her OnlyFriend Eileen and then kill her to harvest her heart. When Tsubaki learns about this, [[MindRape she]] [[SplitPersonalityTakeover does not]] [[RoaringRampageOfRevenge take] [[KillTheCutie it well]].]]

%%%* Tsubaki Kakyouin aka "Tsubaki-hime" and [[spoiler:Muraki's fiancée]] Ukyou Sakuraiji, both from ''YamiNoMatsuei''.

* ''[[SailorMoon Sailor Moon S]]'': {{Anti Villain}}ess An occasionally fell into the archetype, getting tired and out of breath easier than [[BrotherSisterIncest her "brother/lover"]] Ali/Seijuuro. Although in An's case this was caused by her starving, since she refused to eat regular food like Ali did, and humans' life energy wasn't available every time she needed it.

** Rin (stomach ulcers [[spoiler: coming from her BrokenBird personality and the stress of her [[AbusiveParents horrible former home life]] ]]) and [[spoiler: Akito (unclear illness that comes from the stress of being the God of the Zodiac, which may be the same sickness that killed her father Akira)]]. Even though they're sick, they both scare the living crap out of people: Rin because she's headstrong and harsh, [[spoiler: Akito because she's the feared leader of the Sohma clan.]]
** In [[spoiler: Akito]]'s case, her illness [[spoiler: ''may'' be more psychosomatic than anything. She's shown doing a LOT better in the health fields after her HeelFaceTurn.]]

* [[spoiler: Akira Sohma, Akito's father]] in FruitsBasket. He always was frail [[spoiler: due to being the God of the Zodiac (as it's mentioned above)]], and by the time the series starts [[spoiler: he's been dead for years. His daughter Akito inherits said illness.]]

* Kosumo Koganehara from MichiyoAkaishi's ''TowaKamoShirenai'' was born with a weak heart, and in fact the manga starts when she has a seizure during her treatment in the USA and needs an urgent transplant, but her extremely rare blood type doesn't allow for an easy one. The donor that saves her life just ''happens'' to be Himiko, a {{Miko}} and MagicalGirlWarrior who has just died via an HeroicSacrifice to save a child, so Kosumo inherits her powers alongside her heart and blood and must take up her demon slaying mission - with the help of Himiko's TallDarkAndHandsome guardian, Hitsuji.

* Toji Suzuhara's off camera sister in ''NeonGenesisEvangelion'': After the injuries she suffers among the civilians caught in the middle of the fight in the first two episodes, Toji is eventually recruited as the pilot of Unit 03 in exchange for her being transferred to NERV's medical facilities. However, [[spoiler:Toji himself is severely crippled when an Angel takes over his Eva.]]