History Characters / ResidentEvil4

A servant of Salazar that now works as a scientist for Los Iluminados. Although we only ever hear from him through notes, Isidro is the one who created both the Novistadors and Salazar's two bodyguards. Initially presented as just a minor new character for a few notes in the remake, Isidro eventually turns out to be the true identity of Verdugo.\\

* TheUnseen: In a sense. While Leon does have multiple encounters with Isidro in the castle, we never get to see what he used to look like before he became Verdugo.

* ActionSurvivor: Ashley may get captured (quite a bit), but she's a normal young woman thrown in a ludicrous scenario that would pose considerable danger to any average person. When the player briefly controls her at one point, she lacks Leon's combat training, but she makes up for it by outrunning and outsmarting Saddler's minions by throwing anything she can grab onto at them, while keeping her nerves together enough to solve puzzles that will aid her escape. She slowly becomes one throughout the course of the remake where she goes from being scared out of her wits to a confident survivor who assists Leon many times; this is also reflected in the gameplay where she starts resisting her captors more often while being carried away as the game proceeds.

* AmbiguouslyRelated: [[spoiler:The way the requests are written suggests he's related to Ramón by referring a stolen emerald as "our heirloom" and defacing Ramón's portrait (and there's a golden egg in the throne room that he's deathly allergic to), and has an understandable contempt for the cult. The fact that he's an arms dealer who's willing to sell weapons to Leon suggests he procured his weapons somewhere if he's wealthy enough to buy and tune them for him]].

* AdaptationalNiceGuy: Subverted. The 2023 remake Saddler is presented on the surface as a WellIntentionedExtremist who sincerely believes in what he preaches that Las Plagas is the key to achieving world peace, unlike the original game where it was implied that he didn't truly believe in the teachings of Los Iluminados and was more interested in accumulating power and taking over the world. However, as Luis notes in Saddler's Animus, the cultist leader is still a megalomaniacal man whose idea of "utopia" is to force the entire world into a deranged culture where daily ritual murders and total oppression are the norm, making it clear that he's only "nice" in the sense that he's convinced of his own twisted self-righteousness.

** In the original game, Krauser falls to the dark side because he ''liked'' his work with SOCOM so much, so when he [[spoiler:all but loses one arm and faces an end to his military career, he turns to Wesker.]]

* AdaptationalNiceGuy: Subverted. The 2023 remake Saddler is presented on the surface as a WellIntentionedExtremist who sincerely believes in what he preaches that Las Plagas is the key to achieving world peace, unlike the original game where it was implied that he didn't truly believe in the teachings of Los Iluminados and was more interested in accumulating power and taking over the world. However, as Luis notes in Saddler's Animus, the cultist leader is still a megalomaniacally twisted man whose idea of "utopia" is a deranged culture where daily ritual murders and total oppression are the norm, making it clear that he's only "nice" in the sense that he's convinced of his own twisted self-righteousness.

* AdaptationalNiceGuy: A downplayed example, since he's still a megalomaniac-to-murderously twisted man in the 2023 remake, but now framed as a WellIntentionedExtremist who sincerely believes what he preaches. The original game implied that he didn't truly believe in the teachings of Los Iluminados and was more interested in accumulating power and taking over the world - though the localization has a line about barring the United States to not "police the world forever". The remake has him claiming that he wants to spread Las Plagas because he wants to bring peace and unity to a world that he sees is filled with hate and suffering. As a result, the remake's version of Saddler does not share the original incarnation's bigotry against Americans.

* SoProudOfYou: In the remake, Ashely saves ''Leon's'' life multiple times with her resourcefulness and bravery; when she asks whether he could be her bodyguard on a ''permanent'' basis, he shows his newfound ''respect'' for her by explaining that he refused because she has ''already'' become a hero who can take on the world ''without'' him by her side.

-->'''-- Luis Sera, 4 (2005)'''\\\

-->'''-- Luis Serra-Navarro, 4 (2023)'''\\\

* BreakOutTheMuseumPiece: His weapon of choice is a Mauser C96 "Red 9", which has not been in production since World War I. An interesting choice for someone who can make laser weaponry (the P.R.L), though as the Mauser [=C96=] was (and still is) popular in Spain [[note]] to the point Spain actually produced a copy- the Astra Model 900- in large numbers, but this copy is chambered in the original 7.63x25mm Mauser cartridge as opposed to the 9x19 one that Luis carries and uses [[/note]] , it is understandable.

* StraightManAndWiseGuy: The Wise Guy to Leon's StraightMan when they're together, being the one to crack jokes and act charming. This dynamic is even more pronounced in the remake due to Luis's expanded screentime.

'''Saddler:''' ''(makes a "Guess I walked into that one." laugh)'' Enjoy the fun.

* AdaptationalHairstyleChange: From a brown, slicked back hair in the original to absolute baldness in the 2023 remake. This was likely done to display the growing Plagas on his head.

* EyesDoNotBelongThere: He's got an eye in his mouth that only pops out when he's taken a lot of damage. He also has eyes on the legs that grow out of his face in OneWingedAngel mode.

* EvilCounterpart: For Leon. Both are love using knives, worked for the US government, and even served on the same mission in ''Darkside Chronicles''. Both of them were also heavily traumatized by events relating to bioweapons, but used those feelings to fuel different causes; Leon dedicates his life to protecting the world from bioweapons, while Krauser is corrupted by the power they offer and now threatens to unleash one on the world. The remake furthers their comparison with a key shot of both characters staring into their ''[[RuleOfSymbolism reflections]]'' on their knives at different points, first when Leon gets a glimpse at Krauser's perspective thanks to Saddler's HiveMind, [[spoiler:and then right before he finishes off Krauser in their final battle.]]

* FirstNameBasis: Invoked in the remake. He insists on being referred to only by his first name, Ramón.

* AdaptationalVillainy: In the original, Ramón is implied to have been a more composed and decent man before the Plaga infection drove him into madness, judging from his housekeeper's note. The remake changes this by establishing that he was already an evil bastard long before Saddler entered the picture, with the housekeeper now recalling that Ramón had a violent and sadistic temperament even as a child.
* AintTooProudToBeg: In the remake, [[spoiler:when he is moments away from death, rather than trash-talk Leon yet again. Ramón screams out and pathetically begs his master, Lord Saddler, to save him.]]