- LGBT Fanbase: As a Furry Webcomic about a canonically gay couplenote living together, the strip gets a fair bit of interest from the LGBT portion of the Furry Fandom.
- Tearjerker: Although it exists outside the main canon, Vinci's ultimate fate. He spends his life in and out of hospitals battling cancer, until Arty dies saving a woman from a burning house. The cancer picks that moment to return, and faced with the prospect of having his adopted daughter become his caretaker, Vinci commits suicide. As punishment, he's sent to hell and his memory is altered to one in which he spent his entire life alone. Things get better in the end, but it's gratuitously awful nonetheless.
http://tvtropes.org/pmwiki/pmwiki.php/YMMV/VinciAndArty
FollowingYMMV / Vinci and Arty
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