YMMV / Peglin

• Game-Breaker:
  • As The Spiffing Brit shows, grab the "Bad Cheese"^note Deal (20 x # reloads damage to all enemies when reloading) and the "Round Guard"^note You are immune to attack damage while reloading relics and the game becomes an idle simulator where enemies die while keeping you safe (so long as you have a number of orbs less than or equal to your number of discards).
  • Pre-nerf Critsomallos Fleece, full stop. With it, hitting consecutive Crits in a single shot multiplies your damage by 1.3x for each one. With lots of Crits on the board (doable with Critiball or later with Duplication Potion), it's easy to rack up millions of damage in a single shot. While the Fleece was nerfed in an update to make the damage boost additive rather than multiplicative, its old behavior was given to the Ancient Fleece, a secret relic exclusive to Custom mode.
  • Summoning Circle + Matryorbshka. Summoning Circle throws out copies of the next orb in your deck, up to 3 copies at level 3. Matryorbshka has Multiball that scales with its level, resulting in 8 orbs on the pegboard at level 3. Put them together and you get something that clears the pegboard in one turn, and promptly kills whatever you're aiming at.