Retroactive Recognition: Before rising to prominence as a voice actor for shows like Tiny Toon Adventures, Uncle Beano was Joe Alaskey's most well-known on-screen role. Alaskey would eventually become the full-time voice of Daffy Ducknote only Mel Blanc, who died in 1988, has a longer tenure voicing Daffy's role until passing away in 2016.
Steve Burton's debut role was as Evie's boyfriend Chris Fuller. He would later become famous for playing Jason Quartermaine/Morgan on General Hospital.
On the production side, future Simpsons showrunner Mike Scully was a producer and wrote a whole bunch of episodes.